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Gene: Srd5a1 (steroid 5 alpha-reductase 1) Mus musculus
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Symbol: Srd5a1
Name: steroid 5 alpha-reductase 1
RGD ID: 11341
Description: Exhibits 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Involved in androgen biosynthetic process. Predicted to localize to several cellular components, including cell body fiber; neuronal cell body; and perinuclear region of cytoplasm. Is expressed in alimentary system; genitourinary system; hypothalamus; and liver. Human ortholog(s) of this gene implicated in prostate cancer and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1); PARTICIPATES IN testosterone biosynthetic pathway; steroid hormone biosynthetic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610031P22Rik; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; 4930435F02Rik; S5AR 1; SR type 1; Srd5; Srd5a-1; steroid 5-alpha-reductase 1; type 1 5alpha-reductase
Orthologs:
Homo sapiens (human) : SRD5A1 (steroid 5 alpha-reductase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Srd5a1 (steroid 5 alpha-reductase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srd5a1 (steroid 5 alpha-reductase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SRD5A1 (steroid 5 alpha-reductase 1)
Canis lupus familiaris (dog) : SRD5A1 (steroid 5 alpha-reductase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srd5a1 (steroid 5 alpha-reductase 1)
Sus scrofa (pig) : SRD5A1 (steroid 5 alpha-reductase 1)
Chlorocebus sabaeus (African green monkey) : SRD5A1 (steroid 5 alpha-reductase 1)
Heterocephalus glaber (naked mole-rat) : Srd5a1 (steroid 5 alpha-reductase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1369,573,449 - 69,611,442 (-)EnsemblGRCm38mm10GRCm38
GRCm381369,573,449 - 69,611,485 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371369,712,327 - 69,750,341 (-)NCBIGRCm37mm9NCBIm37
MGSCv361370,040,821 - 70,078,835 (-)NCBImm8
Celera1371,919,533 - 71,956,201 (-)NCBICelera
Cytogenetic Map13B3-C1NCBI
cM Map1335.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Srd5a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11341
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.