Gata6 (GATA binding protein 6) - Rat Genome Database

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Gene: Gata6 (GATA binding protein 6) Mus musculus
Analyze
Symbol: Gata6
Name: GATA binding protein 6
RGD ID: 735651
MGI Page MGI
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including animal organ development; cardiac muscle hypertrophy in response to stress; and endodermal cell fate determination. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and heart. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA6 (GATA binding protein 6); INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA410133; GATA-6; GATA-binding factor 6; GATA-binding protein 6; transcription factor GATA-6
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391811,052,510 - 11,085,636 (+)NCBIGRCm39mm39
GRCm39 Ensembl1811,052,064 - 11,085,635 (+)Ensembl
GRCm381811,052,510 - 11,085,636 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1811,052,064 - 11,085,635 (+)EnsemblGRCm38mm10GRCm38
MGSCv371811,052,508 - 11,085,633 (+)NCBIGRCm37mm9NCBIm37
MGSCv361811,052,506 - 11,085,628 (+)NCBImm8
Celera1811,079,782 - 11,114,690 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map185.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-ethoxyethanol  (ISO)
2-methoxyethanol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-methylcholanthrene  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-fluorouracil  (EXP)
8'-apo-beta,psi-caroten-8'-al  (ISO)
9-cis-retinoic acid  (ISO)
acetic acid  (EXP)
aflatoxin B1  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-4-oxoretinol  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
ammonium chloride  (ISO)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (EXP)
beta-carotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromochloroacetic acid  (EXP)
cadmium dichloride  (ISO)
calciol  (EXP)
carbon nanotube  (EXP)
CHIR 99021  (ISO)
choline  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (EXP)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichromium trioxide  (ISO)
diclofenac  (EXP)
dimethyl sulfoxide  (ISO)
dimethylarsinous acid  (ISO)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
gentamycin  (ISO)
indometacin  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methylmercury chloride  (ISO)
N-ethyl-N-nitrosourea  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
nitrofen  (ISO)
NS-398  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
progesterone  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sulindac sulfone  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
trimellitic anhydride  (EXP)
uranium atom  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
warfarin  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ formation  (IMP)
cardiac muscle cell differentiation  (IEP,IGI,IMP)
cardiac muscle hypertrophy in response to stress  (IMP)
cardiac muscle tissue development  (IGI)
cardiac vascular smooth muscle cell differentiation  (ISO)
cell fate commitment  (IBA)
cellular response to BMP stimulus  (IDA)
cellular response to gonadotropin stimulus  (IDA)
cellular response to hypoxia  (ISO)
club cell differentiation  (IGI)
endodermal cell differentiation  (IMP)
endodermal cell fate determination  (IDA)
epithelial cell differentiation  (IBA,IMP)
gene expression  (IMP)
heart contraction  (IMP)
in utero embryonic development  (IMP)
intestinal epithelial cell differentiation  (ISO)
liver development  (IMP)
lung saccule development  (IGI)
male gonad development  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
negative regulation of sebum secreting cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (IBA,ISO)
negative regulation of transcription, DNA-templated  (ISO)
negative regulation of transforming growth factor beta1 production  (ISO)
negative regulation of transforming growth factor beta2 production  (ISO)
odontogenesis of dentin-containing tooth  (ISO)
outflow tract septum morphogenesis  (ISO)
pancreas development  (IMP)
pancreatic A cell differentiation  (IMP)
phospholipid metabolic process  (IGI)
positive regulation of angiogenesis  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of cardiac muscle cell apoptotic process  (ISO)
positive regulation of cardiac muscle cell proliferation  (IGI)
positive regulation of cardiac muscle myoblast proliferation  (ISO)
positive regulation of cardioblast differentiation  (IEP)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IGI,IMP,ISO)
positive regulation of transcription, DNA-templated  (IDA,ISO)
positive regulation of transforming growth factor beta activation  (ISO)
regulation of antimicrobial humoral response  (ISO)
regulation of cell cycle  (ISO)
regulation of gene expression  (IGI)
regulation of transcription by RNA polymerase II  (IEA)
regulation of transcription, DNA-templated  (IEA)
response to cAMP  (ISO)
response to estrogen  (IDA)
response to growth factor  (ISO)
response to retinoic acid  (ISO)
response to toxic substance  (ISO)
response to xenobiotic stimulus  (ISO)
sebaceous gland cell differentiation  (ISO)
sinoatrial node development  (IMP)
skin epidermis development  (ISO)
smooth muscle cell differentiation  (ISO)
tube morphogenesis  (IGI)
type B pancreatic cell differentiation  (IMP)
type II pneumocyte differentiation  (IGI)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta morphology  (IAGP)
abnormal aorta smooth muscle morphology  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cardiogenic mesoderm morphology  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal endoderm development  (IAGP)
abnormal fetal cardiomyocyte morphology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal heart layer morphology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal liver bud morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung epithelium morphology  (IAGP)
abnormal lung saccule morphology  (IAGP)
abnormal primitive endoderm morphology  (IAGP)
abnormal pulmonary alveolus epithelium morphology  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal visceral endoderm morphology  (IAGP)
absent alveolar lamellar bodies  (IAGP)
absent fetal ductus arteriosus  (IAGP)
absent heart  (IAGP)
absent heart tube  (IAGP)
absent primitive endoderm  (IAGP)
aorta dilation  (IAGP)
aorta hypoplasia  (IAGP)
aortic arch hypoplasia  (IAGP)
cyanosis  (IAGP)
decreased embryo size  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased fetal cardiomyocyte proliferation  (IAGP)
decreased inner cell mass proliferation  (IAGP)
decreased surfactant secretion  (IAGP)
double outlet right ventricle  (IAGP)
edema  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
hemorrhage  (IAGP)
increased embryonic epiblast cell apoptosis  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
interrupted aortic arch  (IAGP)
irregular heartbeat  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
oligodactyly  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
persistent truncus arteriosis  (IAGP)
polydactyly  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
preaxial polydactyly  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
reduced fertility  (IAGP)
retroesophageal right subclavian artery  (IAGP)
small embryonic epiblast  (IAGP)
small liver  (IAGP)
thick lung-associated mesenchyme  (IAGP)
thin myocardium  (IAGP)
thin myocardium compact layer  (IAGP)
thin ventricular wall  (IAGP)
ventricular septal defect  (IAGP)
References

Additional References at PubMed
PMID:7671812   PMID:8660897   PMID:8703130   PMID:8812463   PMID:9119112   PMID:9136932   PMID:9136933   PMID:9231805   PMID:9566909   PMID:9738004   PMID:9832509   PMID:9895320  
PMID:10067876   PMID:10349636   PMID:10364163   PMID:10518495   PMID:10608869   PMID:10617462   PMID:10739965   PMID:10779506   PMID:10888889   PMID:10892744   PMID:10922068   PMID:11042159  
PMID:11076861   PMID:11171334   PMID:11217851   PMID:11245568   PMID:11290504   PMID:11356841   PMID:11429286   PMID:11544199   PMID:11578865   PMID:11724781   PMID:11733512   PMID:11914369  
PMID:11937486   PMID:11959831   PMID:12114210   PMID:12130579   PMID:12149478   PMID:12466851   PMID:12530677   PMID:12606287   PMID:12606418   PMID:14511480   PMID:14516673   PMID:14610273  
PMID:14662776   PMID:14681479   PMID:15363409   PMID:15464586   PMID:15539431   PMID:15542856   PMID:15550397   PMID:15591218   PMID:15618518   PMID:15766748   PMID:15767668   PMID:15902305  
PMID:15929941   PMID:15987774   PMID:16137232   PMID:16141072   PMID:16141073   PMID:16162334   PMID:16199866   PMID:16199874   PMID:16293227   PMID:16458891   PMID:16510470   PMID:16557299  
PMID:16602821   PMID:16611361   PMID:16618415   PMID:16621466   PMID:16678776   PMID:16847256   PMID:16887115   PMID:16912278   PMID:16940177   PMID:17060609   PMID:17069789   PMID:17142311  
PMID:17164424   PMID:17274974   PMID:17303760   PMID:17397913   PMID:17428829   PMID:17605826   PMID:17615266   PMID:17936262   PMID:18159948   PMID:18191120   PMID:18206867   PMID:18212046  
PMID:18287559   PMID:18303859   PMID:18324732   PMID:18391535   PMID:18400219   PMID:18448675   PMID:18536717   PMID:18617694   PMID:18635606   PMID:18725515   PMID:18816845   PMID:18832096  
PMID:18974875   PMID:19015235   PMID:19084512   PMID:19174539   PMID:19501129   PMID:19551151   PMID:19649254   PMID:19666519   PMID:19706423   PMID:19782130   PMID:19889636   PMID:20059953  
PMID:20123909   PMID:20159597   PMID:20185795   PMID:20211142   PMID:20235219   PMID:20308546   PMID:20356956   PMID:20412781   PMID:20417598   PMID:20479880   PMID:20501701   PMID:20531244  
PMID:20558824   PMID:20705924   PMID:20826529   PMID:20925113   PMID:21126317   PMID:21127043   PMID:21138972   PMID:21146513   PMID:21262227   PMID:21267068   PMID:21350014   PMID:21471155  
PMID:21511879   PMID:21514437   PMID:21515253   PMID:21633169   PMID:21704616   PMID:21731673   PMID:21757651   PMID:21768366   PMID:21779394   PMID:21839733   PMID:21873635   PMID:21896782  
PMID:21908788   PMID:21954113   PMID:22001906   PMID:22116936   PMID:22315423   PMID:22327294   PMID:22424930   PMID:22431569   PMID:22434075   PMID:22554936   PMID:22589735   PMID:22607194  
PMID:22711520   PMID:22713603   PMID:22733991   PMID:22751695   PMID:22855527   PMID:22863011   PMID:22898775   PMID:22932696   PMID:22982455   PMID:22988430   PMID:23002247   PMID:23006325  
PMID:23006330   PMID:23028652   PMID:23193166   PMID:23213461   PMID:23275439   PMID:23369715   PMID:23471215   PMID:23554936   PMID:23565059   PMID:23728800   PMID:23747191   PMID:23760955  
PMID:23788624   PMID:23791728   PMID:23824537   PMID:24036311   PMID:24063807   PMID:24064357   PMID:24146773   PMID:24168030   PMID:24284823   PMID:24292013   PMID:24367609   PMID:24380800  
PMID:24391969   PMID:24415953   PMID:24449835   PMID:24472151   PMID:24504341   PMID:24550112   PMID:24586749   PMID:24633789   PMID:24650916   PMID:24661562   PMID:24662306   PMID:24698271  
PMID:24705356   PMID:24762537   PMID:24792964   PMID:24835466   PMID:24859004   PMID:24866383   PMID:24899573   PMID:24929016   PMID:24939938   PMID:24952462   PMID:24952961   PMID:24970044  
PMID:25015078   PMID:25024137   PMID:25127677   PMID:25209243   PMID:25294942   PMID:25340657   PMID:25488664   PMID:25495347   PMID:25569111   PMID:25588837   PMID:25596178   PMID:25613430  
PMID:25668066   PMID:25810521   PMID:25933105   PMID:25969542   PMID:26023924   PMID:26027919   PMID:26109048   PMID:26199412   PMID:26443623   PMID:26498761   PMID:26505174   PMID:26510866  
PMID:26511924   PMID:26678830   PMID:26687508   PMID:26932670   PMID:26979619   PMID:26996597   PMID:27062926   PMID:27289030   PMID:27292645   PMID:27320915   PMID:27352137   PMID:27601327  
PMID:27908934   PMID:28087629   PMID:28289135   PMID:28298438   PMID:28346476   PMID:28401892   PMID:28504705   PMID:28538179   PMID:28552557   PMID:28552559   PMID:28710293   PMID:28870993  
PMID:28952437   PMID:29101321   PMID:29168693   PMID:29197504   PMID:29263149   PMID:29335067   PMID:29339785   PMID:29388792   PMID:29412136   PMID:29445086   PMID:29454706   PMID:29509905  
PMID:29567669   PMID:29593216   PMID:29635272   PMID:29666070   PMID:29964027   PMID:30033638   PMID:30250184   PMID:30256721   PMID:30428088   PMID:30530745   PMID:30567484   PMID:30735538  
PMID:30842444   PMID:30886049   PMID:30959515   PMID:31006513   PMID:31048328   PMID:31120883   PMID:31231034   PMID:31315031   PMID:31320324   PMID:31422919   PMID:31982409   PMID:32145025  
PMID:32157212   PMID:32413083   PMID:32433954   PMID:32907838   PMID:32989249   PMID:33230114   PMID:33443158   PMID:33479343   PMID:33486744   PMID:34332615  


Genomics

Comparative Map Data
Gata6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391811,052,510 - 11,085,636 (+)NCBIGRCm39mm39
GRCm39 Ensembl1811,052,064 - 11,085,635 (+)Ensembl
GRCm381811,052,510 - 11,085,636 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1811,052,064 - 11,085,635 (+)EnsemblGRCm38mm10GRCm38
MGSCv371811,052,508 - 11,085,633 (+)NCBIGRCm37mm9NCBIm37
MGSCv361811,052,506 - 11,085,628 (+)NCBImm8
Celera1811,079,782 - 11,114,690 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map185.63NCBI
GATA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1822,169,589 - 22,202,528 (+)EnsemblGRCh38hg38GRCh38
GRCh381822,169,589 - 22,202,528 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371819,749,550 - 19,782,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361818,003,414 - 18,036,225 (+)NCBINCBI36hg18NCBI36
Build 341818,003,413 - 18,036,225NCBI
Celera1816,555,843 - 16,588,650 (+)NCBI
Cytogenetic Map18q11.2NCBI
HuRef1816,596,234 - 16,629,323 (+)NCBIHuRef
CHM1_11819,676,426 - 19,709,511 (+)NCBICHM1_1
Gata6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2182,188,121 - 2,219,532 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl182,188,121 - 2,219,532 (+)Ensembl
Rnor_6.0182,415,821 - 2,447,087 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,416,552 - 2,446,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,436,500 - 2,465,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,504,264 - 2,534,648 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1182,504,263 - 2,534,648 (+)NCBI
Celera182,065,111 - 2,096,513 (+)NCBICelera
RH 3.4 Map1810.8RGD
Cytogenetic Map18p13NCBI
GATA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11819,046,132 - 19,078,398 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01815,411,764 - 15,444,402 (+)NCBIMhudiblu_PPA_v0panPan3
GATA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1765,932,114 - 65,962,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha765,386,151 - 65,418,363 (-)NCBI
ROS_Cfam_1.0765,995,800 - 66,028,019 (-)NCBI
UMICH_Zoey_3.1765,662,867 - 65,695,075 (-)NCBI
UNSW_CanFamBas_1.0765,685,301 - 65,716,538 (-)NCBI
UU_Cfam_GSD_1.0765,985,181 - 66,017,395 (-)NCBI
Gata6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494461,971,676 - 62,001,620 (-)NCBI
SpeTri2.0NW_0049365501,814,336 - 1,844,399 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GATA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6107,282,847 - 107,314,634 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16107,282,709 - 107,314,725 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2699,758,773 - 99,790,688 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GATA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11858,312,328 - 58,345,472 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1858,311,482 - 58,343,746 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605033,085,880 - 33,119,030 (-)NCBIVero_WHO_p1.0
Gata6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247709,772,818 - 9,799,837 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Gata6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,084,567 - 11,085,060UniSTSGRCm38
MGSCv371811,084,565 - 11,085,058UniSTSGRCm37
Celera1811,113,622 - 11,114,115UniSTS
Cytogenetic Map18A1UniSTS
cM Map183.0UniSTS
RH124933  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,085,018 - 11,085,164UniSTSGRCm38
MGSCv371811,085,016 - 11,085,162UniSTSGRCm37
Celera1811,114,073 - 11,114,219UniSTS
Cytogenetic Map18A1UniSTS
cM Map183.0UniSTS
RH125931  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,085,032 - 11,085,281UniSTSGRCm38
MGSCv371811,085,030 - 11,085,279UniSTSGRCm37
Celera1811,114,087 - 11,114,336UniSTS
Cytogenetic Map18A1UniSTS
cM Map183.0UniSTS
Whitehead/MRC_RH18184.21UniSTS
UniSTS:237736  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,084,382 - 11,084,673UniSTSGRCm38
MGSCv371811,084,380 - 11,084,671UniSTSGRCm37
Celera1811,113,437 - 11,113,728UniSTS
Cytogenetic Map18A1UniSTS
cM Map183.0UniSTS
UniSTS:237737  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,085,041 - 11,085,300UniSTSGRCm38
MGSCv371811,085,039 - 11,085,298UniSTSGRCm37
Celera1811,114,096 - 11,114,355UniSTS
Cytogenetic Map18A1UniSTS
cM Map183.0UniSTS
PMC203309P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,084,869 - 11,084,949UniSTSGRCm38
MGSCv371811,084,867 - 11,084,947UniSTSGRCm37
Celera1811,113,924 - 11,114,004UniSTS
Cytogenetic Map18A1UniSTS
cM Map183.0UniSTS
Gata6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,063,048 - 11,064,603UniSTSGRCm38
MGSCv371811,063,046 - 11,064,601UniSTSGRCm37
Celera1811,091,789 - 11,093,344UniSTS
Cytogenetic Map18A1UniSTS
Gata6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381811,054,935 - 11,055,067UniSTSGRCm38
MGSCv371811,054,933 - 11,055,065UniSTSGRCm37
Celera1811,082,207 - 11,082,339UniSTS
Cytogenetic Map18A1UniSTS
Gata6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map18A1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142127Rafaril_mRafar interacting locus (mouse)Not determined18123108555Mouse
14928307Manh83_mmandible shape 83 (mouse)18126902168Mouse
11354953Mom21_mmodifier of Min 21 (mouse)18128760766Mouse
12801458Intmrm3_mintima/media ratio modifier 3 (mouse)18131587699Mouse
12801462Intim3_mintima modifier 3 (mouse)18131587699Mouse
13207585Mwmlpt3_mMorris water maze latency to platform, training, 3 (mouse)18133414682Mouse
13207589Mwmlpa3_mMorris water maze latency to platform, all, 3 (mouse)18133414682Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060800000Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961139571Mouse
4142250Idd21.3_minsulin dependent diabetes susceptibility 21.3 (mouse)Not determined18610840421513420Mouse
1558873Hrtfm7_mheart failure modifier 7 (mouse)Not determined18795390741954049Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:296
Count of miRNA genes:259
Interacting mature miRNAs:273
Transcripts:ENSMUST00000047762
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB034243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB119275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC130654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF179425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF197939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI120546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ243146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB042635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG079878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM214048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY084328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S82462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000047762   ⟹   ENSMUSP00000041774
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1811,052,470 - 11,085,635 (+)Ensembl
GRCm38.p6 Ensembl1811,052,470 - 11,085,635 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231831
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1811,052,508 - 11,057,583 (+)Ensembl
GRCm38.p6 Ensembl1811,052,508 - 11,057,583 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234512   ⟹   ENSMUSP00000157117
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1811,052,064 - 11,054,261 (+)Ensembl
GRCm38.p6 Ensembl1811,052,064 - 11,054,261 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234722
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1811,055,038 - 11,059,350 (+)Ensembl
GRCm38.p6 Ensembl1811,055,038 - 11,059,350 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234971
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1811,059,047 - 11,063,461 (+)Ensembl
GRCm38.p6 Ensembl1811,059,047 - 11,063,461 (+)Ensembl
RefSeq Acc Id: ENSMUST00000235081   ⟹   ENSMUSP00000157128
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1811,053,044 - 11,054,556 (+)Ensembl
GRCm38.p6 Ensembl1811,053,044 - 11,054,556 (+)Ensembl
RefSeq Acc Id: NM_010258   ⟹   NP_034388
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391811,052,510 - 11,085,635 (+)NCBI
GRCm381811,052,510 - 11,085,635 (+)NCBI
MGSCv371811,052,508 - 11,085,633 (+)RGD
Celera1811,079,782 - 11,114,690 (+)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017317834   ⟹   XP_017173323
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391811,054,036 - 11,085,636 (+)NCBI
GRCm381811,054,036 - 11,085,636 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034388   ⟸   NM_010258
- UniProtKB: Q61169 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017173323   ⟸   XM_017317834
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000041774   ⟸   ENSMUST00000047762
RefSeq Acc Id: ENSMUSP00000157128   ⟸   ENSMUST00000235081
RefSeq Acc Id: ENSMUSP00000157117   ⟸   ENSMUST00000234512

Promoters
RGD ID:6829241
Promoter ID:MM_KWN:24597
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   3T3L1_Day4,   ES_Cell,   Kidney,   Liver
Transcripts:NM_010258,   UC008EBJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361811,052,366 - 11,052,866 (+)MPROMDB
RGD ID:13677104
Promoter ID:EPDNEW_M22701
Type:initiation region
Name:Gata6_2
Description:Mus musculus GATA binding protein 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22702  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381811,052,467 - 11,052,527EPDNEW
RGD ID:13677106
Promoter ID:EPDNEW_M22702
Type:initiation region
Name:Gata6_1
Description:Mus musculus GATA binding protein 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22701  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381811,052,654 - 11,052,714EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107516 AgrOrtholog
Ensembl Genes ENSMUSG00000005836 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000041774 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157117 UniProtKB/TrEMBL
  ENSMUSP00000157128 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047762 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000234512 UniProtKB/TrEMBL
  ENSMUST00000235081 UniProtKB/TrEMBL
Gene3D-CATH 3.30.50.10 UniProtKB/Swiss-Prot
InterPro GATA_N UniProtKB/Swiss-Prot
  TF_GATA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transcription_factor_GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_GATA UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report mmu:14465 UniProtKB/Swiss-Prot
MGD MGI:107516 ENTREZGENE
NCBI Gene 14465 ENTREZGENE
PANTHER PTHR10071 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10071:SF23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GATA UniProtKB/Swiss-Prot
  GATA-N UniProtKB/Swiss-Prot
PhenoGen Gata6 PhenoGen
PRINTS GATAZNFINGER UniProtKB/Swiss-Prot
PROSITE GATA_ZN_FINGER_1 UniProtKB/Swiss-Prot
  GATA_ZN_FINGER_2 UniProtKB/Swiss-Prot
SMART ZnF_GATA UniProtKB/Swiss-Prot
UniProt A0A3Q4EHT4_MOUSE UniProtKB/TrEMBL
  A0A3Q4L2W4_MOUSE UniProtKB/TrEMBL
  GATA6_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P97729 UniProtKB/Swiss-Prot
  Q3UQJ2 UniProtKB/Swiss-Prot
  Q9QZK3 UniProtKB/Swiss-Prot