Lipe (lipase, hormone sensitive) - Rat Genome Database

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Gene: Lipe (lipase, hormone sensitive) Mus musculus
Analyze
Symbol: Lipe
Name: lipase, hormone sensitive
RGD ID: 10872
MGI Page MGI
Description: Enables carboxylic ester hydrolase activity; protein kinase binding activity; and serine hydrolase activity. Involved in ether lipid metabolic process and lipid catabolic process. Acts upstream of or within cellular lipid catabolic process and cellular response to cold. Located in cytosol; lipid droplet; and membrane. Is expressed in adipose tissue; ileum; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in arteriosclerosis; familial partial lipodystrophy type 6; and hypertension. Orthologous to human LIPE (lipase E, hormone sensitive type); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (R)-adrenaline; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933403G17Rik; H; hormone-sensitive lipase; HSL; monoacylglycerol lipase LIPE; REH; retinyl ester hydrolase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,078,952 - 25,097,911 (-)NCBIGRCm39mm39
GRCm39 Ensembl725,078,952 - 25,098,135 (-)Ensembl
GRCm38725,379,527 - 25,398,486 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,379,527 - 25,398,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv37726,164,546 - 26,181,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv36725,088,287 - 25,104,747 (-)NCBImm8
Celera719,994,853 - 20,011,313 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (EXP)
(R)-adrenaline  (EXP,ISO)
(R)-lipoic acid  (EXP)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose 6-phosphate  (EXP)
26-hydroxycholesterol  (EXP)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aldehydo-D-glucosamine 6-phosphate  (EXP)
all-trans-retinyl palmitate  (ISO)
amiodarone  (EXP)
ammonium chloride  (ISO)
ATP  (ISO)
beta-D-glucosamine 6-sulfate  (EXP)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
boric acid  (EXP)
bucladesine  (EXP,ISO)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
deoxycholic acid  (EXP)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dichlorine  (ISO)
dichloroacetic acid  (EXP)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
finasteride  (ISO)
flavonoids  (ISO)
gadolinium trichloride  (EXP)
genistein  (EXP)
glycidol  (ISO)
isoprenaline  (EXP,ISO)
L-methionine  (EXP)
Licarin A  (EXP)
lipoic acid  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
monosodium L-glutamate  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
nicotinic acid  (ISO)
ozone  (EXP,ISO)
papaverine  (ISO)
perfluorooctanoic acid  (ISO)
phosphatidylcholine  (EXP)
pirinixic acid  (EXP,ISO)
quercetin  (EXP)
resveratrol  (EXP,ISO)
rimonabant  (EXP)
rotenone  (ISO)
scopoletin  (ISO)
sirolimus  (EXP)
sodium arsenite  (EXP)
streptozocin  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
telmisartan  (EXP)
tenofovir disoproxil fumarate  (ISO)
Tesaglitazar  (ISO)
theophylline  (ISO)
titanium dioxide  (EXP)
troglitazone  (EXP,ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vinclozolin  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
caveola  (ISS)
cytoplasm  (ISO,ISS)
cytosol  (IDA,ISO)
extracellular space  (ISO)
lipid droplet  (IDA)
membrane  (IDA)
mitochondrion  (ISS)
nucleus  (ISS)
plasma membrane  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal fat pad morphology  (IAGP)
abnormal adipose tissue physiology  (IAGP)
abnormal brown adipose tissue morphology  (IAGP)
abnormal brown adipose tissue physiology  (IAGP)
abnormal cholesterol homeostasis  (IAGP)
abnormal circulating cholesterol level  (IAGP)
abnormal circulating free fatty acids level  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal epididymis morphology  (IAGP)
abnormal fat cell morphology  (IAGP)
abnormal fatty acids level  (IAGP)
abnormal feces composition  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal heart morphology  (IEA)
abnormal hepatic glucose production  (IAGP)
abnormal insulin secretion  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal lipid level  (IAGP)
abnormal lipolysis  (IAGP)
abnormal metabolism  (IAGP)
abnormal pancreatic beta cell morphology  (IAGP)
abnormal seminiferous tubule epithelium morphology  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermiogenesis  (IAGP)
abnormal testis morphology  (IAGP)
abnormal triglyceride level  (IAGP)
abnormal white adipose tissue morphology  (IAGP)
abnormal white adipose tissue physiology  (IAGP)
abnormal white fat cell morphology  (IAGP)
asthenozoospermia  (IAGP)
azoospermia  (IAGP)
decreased body weight  (IAGP)
decreased circulating adiponectin level  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glycerol level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased lean body mass  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased male germ cell number  (IAGP)
decreased muscle cell glucose uptake  (IAGP)
decreased skeletal muscle glycogen level  (IAGP)
decreased subcutaneous adipose tissue amount  (IAGP)
decreased susceptibility to diet-induced obesity  (IAGP)
decreased testis weight  (IAGP)
decreased triglyceride level  (IAGP)
decreased white adipose tissue amount  (IAGP)
enlarged heart  (IEA)
hyperglycemia  (IAGP)
impaired glucose tolerance  (IAGP)
increased bone mineral density  (IEA)
increased brain weight  (IEA)
increased brown adipose tissue amount  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating free fatty acids level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating leptin level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased fat cell size  (IAGP)
increased food intake  (IAGP)
increased lean body mass  (IEA)
increased oxygen consumption  (IAGP)
increased pancreatic beta cell mass  (IAGP)
increased percent body fat/body weight  (IAGP)
increased susceptibility to atherosclerosis  (IAGP)
increased triglyceride level  (IAGP)
insulin resistance  (IAGP)
male infertility  (IAGP)
oligozoospermia  (IAGP)
pancreatic islet hyperplasia  (IAGP)
reduced male fertility  (IAGP)
small testis  (IAGP)
References

Additional References at PubMed
PMID:7560076   PMID:7698747   PMID:7698777   PMID:8104872   PMID:8105016   PMID:8263420   PMID:8798769   PMID:8827514   PMID:9060404   PMID:9077551   PMID:9173930   PMID:9446609  
PMID:9582279   PMID:9615220   PMID:10349636   PMID:10639158   PMID:11042159   PMID:11063252   PMID:11076861   PMID:11076952   PMID:11316346   PMID:11440986   PMID:11522661   PMID:11551864  
PMID:11564684   PMID:11717312   PMID:11751901   PMID:11809748   PMID:12040188   PMID:12193545   PMID:12477932   PMID:12482847   PMID:12832420   PMID:12835327   PMID:12865325   PMID:12923228  
PMID:12954598   PMID:13129924   PMID:14643795   PMID:14657254   PMID:14752112   PMID:15142983   PMID:15220197   PMID:15242332   PMID:15271647   PMID:15292223   PMID:15345679   PMID:15550674  
PMID:15701680   PMID:15878856   PMID:15961788   PMID:16091387   PMID:16141072   PMID:16141073   PMID:16199803   PMID:16243839   PMID:16765472   PMID:16804080   PMID:16818490   PMID:16985254  
PMID:17026959   PMID:17074755   PMID:17114792   PMID:17134676   PMID:17215164   PMID:17711991   PMID:17886267   PMID:18335062   PMID:18337240   PMID:18480494   PMID:18492774   PMID:18572100  
PMID:18664600   PMID:18804448   PMID:18824087   PMID:19023560   PMID:19246492   PMID:19491295   PMID:19515989   PMID:19619509   PMID:19706782   PMID:19717842   PMID:19723498   PMID:19755426  
PMID:19785415   PMID:20107043   PMID:20143880   PMID:20435159   PMID:20534721   PMID:20625037   PMID:20950707   PMID:21111707   PMID:21180279   PMID:21241784   PMID:21267068   PMID:21454566  
PMID:21464445   PMID:21505145   PMID:21543206   PMID:21566206   PMID:21677750   PMID:21680814   PMID:21738729   PMID:21857651   PMID:21969372   PMID:22842588   PMID:22988039   PMID:23066022  
PMID:23362264   PMID:23369366   PMID:23431266   PMID:23471217   PMID:23878361   PMID:24086110   PMID:24194600   PMID:24196706   PMID:24265455   PMID:24440819   PMID:24797631   PMID:24891333  
PMID:24945349   PMID:25100058   PMID:25351614   PMID:25535287   PMID:25677823   PMID:25732851   PMID:25879679   PMID:26122391   PMID:26143381   PMID:26220403   PMID:27185876   PMID:27355565  
PMID:27489310   PMID:27596982   PMID:27626380   PMID:27754788   PMID:27920259   PMID:27974211   PMID:28364022   PMID:28459858   PMID:28488768   PMID:28851734   PMID:29232702   PMID:29728617  
PMID:30086728   PMID:30352954   PMID:30862682   PMID:30937958   PMID:32361002   PMID:33372146   PMID:33692445  


Genomics

Comparative Map Data
Lipe
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,078,952 - 25,097,911 (-)NCBIGRCm39mm39
GRCm39 Ensembl725,078,952 - 25,098,135 (-)Ensembl
GRCm38725,379,527 - 25,398,486 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,379,527 - 25,398,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv37726,164,546 - 26,181,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv36725,088,287 - 25,104,747 (-)NCBImm8
Celera719,994,853 - 20,011,313 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.78NCBI
LIPE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1942,401,514 - 42,427,388 (-)EnsemblGRCh38hg38GRCh38
GRCh381942,401,512 - 42,427,421 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371942,905,666 - 42,931,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,597,506 - 47,623,418 (-)NCBINCBI36hg18NCBI36
Build 341947,597,505 - 47,623,418NCBI
Celera1939,706,455 - 39,732,367 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,335,797 - 39,361,703 (-)NCBIHuRef
CHM1_11942,907,316 - 42,933,231 (-)NCBICHM1_1
Lipe
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2180,965,612 - 80,984,313 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl180,965,627 - 80,984,310 (-)Ensembl
Rnor_6.0182,248,031 - 82,266,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,248,046 - 82,266,727 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,511,504 - 83,530,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,663,791 - 80,682,480 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,741,901 - 80,760,591 (-)NCBI
Celera175,407,246 - 75,425,931 (-)NCBICelera
Cytogenetic Map1q21NCBI
Lipe
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555514,410 - 530,759 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955555511,085 - 531,165 (+)NCBIChiLan1.0ChiLan1.0
LIPE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11947,881,292 - 47,907,066 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,881,292 - 47,907,066 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01939,289,162 - 39,315,067 (-)NCBIMhudiblu_PPA_v0panPan3
LIPE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,987,862 - 112,006,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,988,029 - 112,006,461 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,412,499 - 111,431,532 (+)NCBI
ROS_Cfam_1.01112,598,798 - 112,617,839 (+)NCBI
UMICH_Zoey_3.11112,153,322 - 112,171,913 (+)NCBI
UNSW_CanFamBas_1.01111,788,548 - 111,807,575 (+)NCBI
UU_Cfam_GSD_1.01112,715,381 - 112,734,429 (+)NCBI
Lipe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,772,658 - 15,792,162 (+)NCBI
SpeTri2.0NW_004936706122,939 - 139,506 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIPE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,540,907 - 49,560,126 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,543,671 - 49,560,126 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,443,742 - 45,454,621 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q12NCBI
LIPE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,604,822 - 36,630,648 (-)NCBI
ChlSab1.1 Ensembl636,605,126 - 36,630,376 (-)Ensembl
Vero_WHO_p1.0NW_02366607314,849,833 - 14,875,994 (-)NCBI
Lipe
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624907360,462 - 379,266 (+)NCBI

Position Markers
RH131319  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38725,379,720 - 25,379,900UniSTSGRCm38
MGSCv37726,164,739 - 26,164,919UniSTSGRCm37
Celera719,995,046 - 19,995,226UniSTS
Cytogenetic Map7A3UniSTS
cM Map75.5UniSTS
U69543  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38725,379,714 - 25,379,843UniSTSGRCm38
MGSCv37726,164,733 - 26,164,862UniSTSGRCm37
Celera719,995,040 - 19,995,169UniSTS
Cytogenetic Map7A3UniSTS
cM Map75.5UniSTS
Whitehead/MRC_RH7367.16UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7269777136697919Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7346321287493512Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360000072900000Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined71028944244289559Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71060637344606511Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71278145246781452Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71278145246781452Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1333306047333196Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71343577947435779Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71360000047700000Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71690336849509583Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71899486940024609Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71958059053580679Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined72014282554142942Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72302446357024609Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72323914857239292Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72341710757417107Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:760
Count of miRNA genes:317
Interacting mature miRNAs:353
Transcripts:ENSMUST00000003207, ENSMUST00000054301, ENSMUST00000105177, ENSMUST00000149349
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001039507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC162443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC169209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF179427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF452490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY513432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01163929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U08187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U08188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U12765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000003207   ⟹   ENSMUSP00000003207
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,078,952 - 25,095,804 (-)Ensembl
GRCm38.p6 Ensembl725,379,527 - 25,396,379 (-)Ensembl
RefSeq Acc Id: ENSMUST00000054301   ⟹   ENSMUSP00000050935
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,079,070 - 25,089,531 (-)Ensembl
GRCm38.p6 Ensembl725,379,645 - 25,390,106 (-)Ensembl
RefSeq Acc Id: ENSMUST00000105177   ⟹   ENSMUSP00000100811
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,096,884 - 25,098,134 (-)Ensembl
GRCm38.p6 Ensembl725,397,459 - 25,398,709 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149349   ⟹   ENSMUSP00000123485
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,079,086 - 25,098,135 (-)Ensembl
GRCm38.p6 Ensembl725,379,661 - 25,398,710 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205698   ⟹   ENSMUSP00000146000
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,087,986 - 25,089,902 (-)Ensembl
GRCm38.p6 Ensembl725,388,561 - 25,390,477 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205923   ⟹   ENSMUSP00000145669
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,082,578 - 25,084,351 (-)Ensembl
GRCm38.p6 Ensembl725,383,153 - 25,384,926 (-)Ensembl
RefSeq Acc Id: ENSMUST00000206588
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,082,599 - 25,083,233 (-)Ensembl
GRCm38.p6 Ensembl725,383,174 - 25,383,808 (-)Ensembl
RefSeq Acc Id: ENSMUST00000206861   ⟹   ENSMUSP00000145665
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,079,086 - 25,088,649 (-)Ensembl
GRCm38.p6 Ensembl725,379,661 - 25,389,224 (-)Ensembl
RefSeq Acc Id: NM_001039507   ⟹   NP_001034596
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,078,952 - 25,089,537 (-)NCBI
GRCm38725,379,527 - 25,390,112 (-)NCBI
MGSCv37726,164,546 - 26,181,006 (-)RGD
Celera719,994,853 - 20,011,313 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010719   ⟹   NP_034849
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,078,952 - 25,095,412 (-)NCBI
GRCm38725,379,527 - 25,395,987 (-)NCBI
MGSCv37726,164,546 - 26,181,006 (-)RGD
Celera719,994,853 - 20,011,313 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539570   ⟹   XP_006539633
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,079,070 - 25,097,911 (-)NCBI
GRCm38725,379,645 - 25,398,486 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006539572   ⟹   XP_006539635
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,079,070 - 25,088,258 (-)NCBI
GRCm38725,379,645 - 25,388,833 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242178   ⟹   XP_030098038
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,079,070 - 25,089,231 (-)NCBI
GRCm38725,379,645 - 25,389,806 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242180   ⟹   XP_030098040
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,079,070 - 25,093,637 (-)NCBI
GRCm38725,379,645 - 25,394,212 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034849   ⟸   NM_010719
- Peptide Label: isoform 1
- UniProtKB: P54310 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001034596   ⟸   NM_001039507
- Peptide Label: isoform 2
- UniProtKB: P54310 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539633   ⟸   XM_006539570
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006539635   ⟸   XM_006539572
- Peptide Label: isoform X2
- UniProtKB: P54310 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030098040   ⟸   XM_030242180
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030098038   ⟸   XM_030242178
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000100811   ⟸   ENSMUST00000105177
RefSeq Acc Id: ENSMUSP00000050935   ⟸   ENSMUST00000054301
RefSeq Acc Id: ENSMUSP00000145665   ⟸   ENSMUST00000206861
RefSeq Acc Id: ENSMUSP00000145669   ⟸   ENSMUST00000205923
RefSeq Acc Id: ENSMUSP00000146000   ⟸   ENSMUST00000205698
RefSeq Acc Id: ENSMUSP00000003207   ⟸   ENSMUST00000003207
RefSeq Acc Id: ENSMUSP00000123485   ⟸   ENSMUST00000149349
Protein Domains
Abhydrolase_3   HSL_N

Promoters
RGD ID:6892282
Promoter ID:EPDNEW_M9587
Type:multiple initiation site
Name:Lipe_1
Description:Mus musculus lipase, hormone sensitive , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9588  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38725,390,114 - 25,390,174EPDNEW
RGD ID:6892274
Promoter ID:EPDNEW_M9588
Type:initiation region
Name:Lipe_2
Description:Mus musculus lipase, hormone sensitive , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9587  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38725,395,626 - 25,395,686EPDNEW
RGD ID:6840262
Promoter ID:MM_KWN:49446
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   Brain,   ES_Cell,   Kidney,   MEF_B6
Transcripts:AK076372_4732471J01RIK,   UC009FSN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,161,041 - 26,162,272 (+)MPROMDB
RGD ID:6848161
Promoter ID:MM_ACW:43895
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_2Hour,   ES_Cell
Transcripts:LIPE.GSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,165,016 - 26,165,942 (-)MPROMDB
RGD ID:6848162
Promoter ID:MM_ACW:43896
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Brain,   Kidney
Transcripts:LIPE.HSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,168,299 - 26,168,799 (-)MPROMDB
RGD ID:6848200
Promoter ID:MM_ACW:43897
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   Brain,   Kidney
Transcripts:LIPE.FSEP07,   MIROTE.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,169,376 - 26,169,876 (-)MPROMDB
RGD ID:6841447
Promoter ID:MM_KWN:49447
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Brain,   Kidney,   Lung
Transcripts:UC009FSP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,173,276 - 26,175,147 (-)MPROMDB
RGD ID:6841446
Promoter ID:MM_KWN:49448
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Brain,   Liver
Transcripts:NM_001039507
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,175,091 - 26,176,102 (-)MPROMDB
RGD ID:6841445
Promoter ID:MM_KWN:49450
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   ES_Cell,   Kidney,   Lung,   Spleen
Transcripts:NM_010719,   UC009FSS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,180,796 - 26,181,747 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96790 AgrOrtholog
Ensembl Genes ENSMUSG00000003123 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000003207 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000050935 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000100811 UniProtKB/TrEMBL
  ENSMUSP00000123485 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000145665 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000145669 UniProtKB/TrEMBL
  ENSMUSP00000146000 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000003207 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000054301 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000105177 UniProtKB/TrEMBL
  ENSMUST00000149349 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000205698 UniProtKB/TrEMBL
  ENSMUST00000205923 UniProtKB/TrEMBL
  ENSMUST00000206861 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AB_hydrolase_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSL_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipase_GDXG_HIS_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipase_GDXG_put_SER_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16890 UniProtKB/Swiss-Prot
MGD MGI:96790 ENTREZGENE
NCBI Gene 16890 ENTREZGENE
Pfam Abhydrolase_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSL_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lipe PhenoGen
PROSITE LIPASE_GDXG_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIPASE_GDXG_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RNR0_MOUSE UniProtKB/TrEMBL
  A0A0U1RPJ0_MOUSE UniProtKB/TrEMBL
  E9Q4M2_MOUSE UniProtKB/TrEMBL
  LIPS_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q6LCY9_MOUSE UniProtKB/TrEMBL
  Q7TQ54_MOUSE UniProtKB/TrEMBL
  Q9CTW2_MOUSE UniProtKB/TrEMBL
  Q9D4C4_MOUSE UniProtKB/TrEMBL
UniProt Secondary P97866 UniProtKB/Swiss-Prot
  Q3TE34 UniProtKB/Swiss-Prot
  Q6GU16 UniProtKB/Swiss-Prot
  Q8CDI9 UniProtKB/Swiss-Prot