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Gene: Insr (insulin receptor) Mus musculus
Symbol: Insr
Name: insulin receptor
Description: Predicted to have several functions, including insulin-like growth factor binding activity; peptide binding activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including animal organ development; positive regulation of cell cycle; and positive regulation of macromolecule biosynthetic process. Localizes to caveola. Predicted to colocalize with cell body; dendrite; and nucleus. Is expressed in several structures, including adrenal gland; decidua; enteric nervous system; heart; and liver. Human ortholog(s) of this gene implicated in Donohue syndrome; diabetes mellitus (multiple); familial hyperinsulinemic hypoglycemia 5; hepatocellular carcinoma; and reproductive organ cancer (multiple). Orthologous to human INSR (insulin receptor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4932439J01Rik; CD220; D630014A15Rik; IR; IR-A; IR-B; RIKEN cDNA D630014A15 gene
Homo sapiens (human) : INSR (insulin receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Insr (insulin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Insr (insulin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : INSR (insulin receptor)
Canis lupus familiaris (dog) : INSR (insulin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Insr (insulin receptor)
Sus scrofa (pig) : INSR (insulin receptor)
Chlorocebus sabaeus (African green monkey) : INSR (insulin receptor)
Heterocephalus glaber (naked mole-rat) : Insr (insulin receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl83,122,061 - 3,279,617 (-)EnsemblGRCm38mm10GRCm38
GRCm3883,150,922 - 3,279,649 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3783,150,922 - 3,279,617 (-)NCBIGRCm37mm9NCBIm37
MGSCv3683,155,669 - 3,279,176 (-)NCBImm8
Celera83,375,321 - 3,505,728 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Insr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10813
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.