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Gene: Gpt (glutamic pyruvic transaminase, soluble) Mus musculus
Symbol: Gpt
Name: glutamic pyruvic transaminase, soluble
RGD ID: 734192
Description: Predicted to have L-alanine:2-oxoglutarate aminotransferase activity and pyridoxal phosphate binding activity. Predicted to be involved in positive regulation of gluconeogenesis. Localizes to extracellular space. Is expressed in several structures, including alimentary system; nervous system; nose; respiratory system; and skeleton. Orthologous to human GPT (glutamic--pyruvic transaminase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; alanine metabolic pathway; argininosuccinic aciduria pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,1-dichloroethene; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300007J06Rik; 2310022B03Rik; A; alanine aminotransferase 1; ALT; ALT1; glutamate pyruvate transaminase 1; glutamic pyruvic transaminase 1, soluble; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; GPT 1; Gpt-; Gpt-1; Gpt1
Homo sapiens (human) : GPT (glutamic--pyruvic transaminase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gpt (glutamic--pyruvic transaminase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpt (glutamic--pyruvic transaminase)
Canis lupus familiaris (dog) : GPT (glutamic--pyruvic transaminase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpt (glutamic--pyruvic transaminase)
Sus scrofa (pig) : GPT (glutamic--pyruvic transaminase)
Chlorocebus sabaeus (African green monkey) : GPT (glutamic--pyruvic transaminase)
Heterocephalus glaber (naked mole-rat) : Gpt (glutamic--pyruvic transaminase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391576,580,926 - 76,583,875 (+)NCBI
GRCm381576,696,726 - 76,699,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,695,716 - 76,699,686 (+)EnsemblGRCm38mm10GRCm38
MGSCv371576,527,194 - 76,530,105 (+)NCBIGRCm37mm9NCBIm37
MGSCv361576,524,016 - 76,526,930 (+)NCBImm8
Celera1578,190,374 - 78,193,285 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gpt
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734192
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.