Gpt (glutamic pyruvic transaminase, soluble) - Rat Genome Database

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Gene: Gpt (glutamic pyruvic transaminase, soluble) Mus musculus
Analyze
Symbol: Gpt
Name: glutamic pyruvic transaminase, soluble
RGD ID: 734192
MGI Page MGI
Description: Predicted to enable L-alanine:2-oxoglutarate aminotransferase activity and pyridoxal phosphate binding activity. Predicted to be involved in positive regulation of gluconeogenesis. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human GPT (glutamic--pyruvic transaminase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; alanine metabolic pathway; argininosuccinic aciduria pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,1-dichloroethene; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300007J06Rik; 2310022B03Rik; A; alanine aminotransferase 1; ALT; ALT1; glutamate pyruvate transaminase 1; glutamic pyruvic transaminase 1, soluble; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; GPT 1; Gpt-; Gpt-1; Gpt1
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,580,926 - 76,583,875 (+)NCBIGRCm39mm39
GRCm39 Ensembl1576,579,916 - 76,583,886 (+)Ensembl
GRCm381576,696,726 - 76,699,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,695,716 - 76,699,686 (+)EnsemblGRCm38mm10GRCm38
MGSCv371576,527,194 - 76,530,105 (+)NCBIGRCm37mm9NCBIm37
MGSCv361576,524,016 - 76,526,930 (+)NCBImm8
Celera1578,190,374 - 78,193,285 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(+)-schisandrin B  (ISO)
(+)-taxifolin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(E)-thiamethoxam  (ISO)
(R)-lipoic acid  (ISO)
(R,R)-tramadol  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-naringenin  (ISO)
1,1,2-trichloroethane  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichlorobenzene  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dichloropropan-2-ol  (EXP)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
1-bromopropane  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
1H-1,2,4-triazole  (ISO)
2',4',6'-trihydroxyacetophenone  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-chloroethanol  (EXP)
2-methoxyethanol  (ISO)
2-methyl-6-(phenylethynyl)pyridine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-hydroxybutyric acid  (EXP)
3-methyladenine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-phenylbutyric acid  (EXP,ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-fluorouracil  (EXP,ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (EXP)
7,12-dimethyltetraphene  (ISO)
7,8-dihydroxycoumarin  (ISO)
8-Epidiosbulbin E acetate  (EXP)
9,11,13-octadecatrienoic acid  (ISO)
acephate  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
alectinib  (ISO)
all-trans-retinol  (ISO)
allethrin  (ISO)
allicin  (EXP)
alloxan  (ISO)
allyl alcohol  (EXP,ISO)
allyl isothiocyanate  (ISO)
allyl methyl disulfide  (EXP)
alpha-amanitin  (EXP)
alpha-galactosylceramide  (EXP)
alpha-linolenic acid  (ISO)
amiodarone  (EXP,ISO)
amlexanox  (EXP)
amlodipine  (ISO)
ammonium chloride  (ISO)
Ammothamnine  (ISO)
amodiaquine  (EXP)
andrographolide  (EXP)
Anetholtrithion  (EXP)
angelicin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
arachidonic acid  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
astragaloside IV  (ISO)
atorvastatin calcium  (EXP,ISO)
azathioprine  (EXP)
azure A  (ISO)
baicalin  (ISO)
bentonite  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
beraprost  (EXP)
berberine  (EXP,ISO)
beta-naphthoflavone  (ISO)
Betanin  (ISO)
bezafibrate  (EXP)
bicuculline  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
boric acid  (ISO)
boron atom  (ISO)
bosentan  (ISO)
bosutinib  (ISO)
bromobenzene  (EXP,ISO)
bromodichloromethane  (EXP)
brucine  (EXP)
buprenorphine  (ISO)
buspirone  (ISO)
Butralin  (ISO)
cabozantinib  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calciol  (ISO)
capsaicin  (ISO)
carbofuran  (ISO)
carbon nanotube  (EXP,ISO)
carfilzomib  (EXP)
carnosic acid  (EXP)
carnosine  (ISO)
carvedilol  (ISO)
catalpol  (ISO)
celastrol  (EXP)
celecoxib  (EXP)
ceritinib  (ISO)
ceruletide  (EXP)
charcoal  (ISO)
chelerythrine  (ISO)
chenodeoxycholic acid  (EXP,ISO)
chlordecone  (EXP)
chlorhexidine gluconate  (ISO)
Chlorobenzilate  (ISO)
Chlorodibromomethane  (EXP,ISO)
chloroethene  (EXP)
chloroform  (EXP,ISO)
chlorogenic acid  (EXP,ISO)
chloroquine  (EXP)
chlorpyrifos  (EXP,ISO)
choline  (EXP,ISO)
chromium(6+)  (EXP,ISO)
chrysin  (ISO)
ciprofloxacin  (EXP)
cis-caffeic acid  (EXP,ISO)
cisplatin  (EXP,ISO)
citral  (ISO)
clodronic acid  (EXP,ISO)
clotrimazole  (EXP)
cobalt dichloride  (ISO)
cobimetinib  (ISO)
cocaine  (EXP)
coenzyme Q10  (EXP,ISO)
Columbin  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crizotinib  (ISO)
crocin-1  (ISO)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
Curcumol  (EXP)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (EXP,ISO)
D-gluconic acid  (ISO)
D-glucose  (ISO)
dabrafenib  (ISO)
dantrolene  (EXP)
dapagliflozin  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (EXP)
dehydroacetic acid  (ISO)
deoxynivalenol  (EXP,ISO)
deoxypodophyllotoxin  (EXP)
dexamethasone  (EXP)
dexmedetomidine  (ISO)
dextromethorphan  (EXP)
diallyl disulfide  (ISO)
Diallyl sulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP,ISO)
dicloxacillin  (EXP)
dicofol  (ISO)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
diethylene glycol monoethyl ether  (ISO)
dihydroartemisinin  (ISO)
dimethylmercury  (ISO)
Diosbulbin B  (EXP)
dioscin  (ISO)
dioxygen  (EXP)
diquat  (EXP,ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
duvoglustat  (EXP)
elemental boron  (ISO)
elemental selenium  (ISO)
ellagic acid  (ISO)
endosulfan  (ISO)
ergothioneine  (ISO)
eriodictyol  (ISO)
eritoran  (EXP)
ethanol  (EXP,ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
ferroheme b  (EXP)
fipronil  (EXP,ISO)
flucloxacillin  (EXP)
flutamide  (EXP)
folic acid  (EXP,ISO)
fomepizole  (EXP,ISO)
fosinopril  (EXP)
fructose  (EXP,ISO)
fucoidan  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
gadolinium trichloride  (EXP,ISO)
gallic acid  (ISO)
gamma-aminobutyric acid  (EXP)
gamma-hexachlorocyclohexane  (ISO)
gamma-mangostin  (EXP)
Ganoderic acid A  (EXP)
gefitinib  (ISO)
gemfibrozil  (EXP)
Geniposide  (EXP)
genistein  (ISO)
geranial  (ISO)
Ginkgoic acid  (ISO)
Ginkgolide A  (EXP)
ginkgolide B  (EXP,ISO)
ginsenoside Rg1  (EXP)
glafenine  (ISO)
glucose  (ISO)
glyburide  (ISO)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
glycyrrhizinic acid  (EXP,ISO)
glyphosate  (ISO)
gold atom  (EXP,ISO)
gold(0)  (EXP,ISO)
Guanabenz  (EXP)
GW 4064  (ISO)
GW 7647  (ISO)
halothane  (EXP)
heme b  (EXP)
heparin  (ISO)
herbacetin  (EXP)
herbicide  (EXP,ISO)
hesperidin  (EXP,ISO)
hexadecanoic acid  (ISO)
homocysteine  (ISO)
hydralazine  (EXP)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
ibrutinib  (ISO)
idelalisib  (EXP)
imidacloprid  (ISO)
imiprothrin  (ISO)
inulin  (ISO)
irbesartan  (EXP)
iron atom  (EXP,ISO)
iron dextran  (ISO)
iron(0)  (EXP,ISO)
iron(3+) sulfate  (ISO)
isoniazide  (ISO)
isoproturon  (ISO)
isorhamnetin  (EXP)
kaempferol  (EXP)
ketoconazole  (EXP,ISO)
L-ascorbic acid  (EXP,ISO)
L-methionine  (EXP,ISO)
lapatinib  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
liquiritigenin  (ISO)
liquiritin  (ISO)
liraglutide  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
lithocholic acid  (EXP)
losartan  (EXP,ISO)
lovastatin  (EXP)
magnesium atom  (ISO)
malathion  (ISO)
Malotilate  (EXP,ISO)
mancozeb  (ISO)
manganese dioxide  (ISO)
mangiferin  (ISO)
melatonin  (ISO)
mercury dichloride  (EXP,ISO)
mesalamine  (ISO)
metformin  (EXP,ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (EXP,ISO)
methotrexate  (ISO)
methoxsalen  (ISO)
methylmercury chloride  (ISO)
microcystin RR  (EXP)
mifepristone  (EXP)
monocrotaline  (EXP,ISO)
monosodium L-glutamate  (EXP)
morin  (ISO)
muscimol  (EXP)
myricitrin  (EXP)
N,N-dimethylformamide  (EXP)
N,N-dimethylglycine  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
naringin  (ISO)
neohesperidin dihydrochalcone  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (EXP,ISO)
nicotinamide  (ISO)
nilotinib  (ISO)
nimesulide  (ISO)
nobiletin  (ISO)
O-methyleugenol  (ISO)
octamethylcyclotetrasiloxane  (EXP)
octreotide  (ISO)
olaparib  (EXP)
oleanolic acid  (EXP)
oleic acid  (ISO)
oleuropein  (ISO)
orlistat  (ISO)
oroxylin A  (EXP)
osimertinib  (ISO)
Oxadiazon  (EXP)
oxycodone  (ISO)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
patulin  (EXP)
penconazole  (EXP)
perfluorodecanoic acid  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perindopril  (EXP)
phenformin  (ISO)
phenobarbital  (ISO)
phenylhydrazine  (EXP,ISO)
phloretin  (EXP)
phorate  (ISO)
pinocembrin  (EXP)
pioglitazone  (ISO)
piperine  (ISO)
pirinixic acid  (EXP,ISO)
polymyxin B2  (EXP)
polyphosphates  (EXP,ISO)
ponatinib  (ISO)
potassium bromate  (ISO)
potassium dichromate  (EXP,ISO)
progesterone  (ISO)
propacetamol  (EXP)
prostaglandin E2  (EXP)
psoralen  (ISO)
puerarin  (EXP)
pyrazinecarboxamide  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
rac-1,2-dichloropropane  (ISO)
regorafenib  (ISO)
resveratrol  (EXP,ISO)
Retrorsine  (EXP)
rifampicin  (EXP,ISO)
rimonabant  (ISO)
rivaroxaban  (ISO)
rosmarinic acid  (ISO)
rotenone  (EXP,ISO)
rottlerin  (EXP,ISO)
Rutecarpine  (EXP)
rutin  (ISO)
ruxolitinib  (EXP)
ryanodine  (EXP)
S-allylcysteine  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
salvianolic acid B  (EXP,ISO)
SB 203580  (EXP)
scopoletin  (ISO)
selenium atom  (ISO)
senecionine  (EXP,ISO)
silibinin  (ISO)
sinapic acid  (ISO)
sirolimus  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP,ISO)
sodium nitrite  (ISO)
sodium sulfite  (ISO)
sodium tungstate  (ISO)
Soman  (ISO)
sorafenib  (EXP,ISO)
squalene  (ISO)
stattic  (EXP)
streptozocin  (EXP,ISO)
succimer  (ISO)
sucrose  (ISO)
sulfasalazine  (EXP)
sunitinib  (EXP,ISO)
syringic acid  (ISO)
T-2 toxin  (EXP)
tamoxifen  (EXP)
tapentadol  (ISO)
taurine  (EXP,ISO)
telmisartan  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
Tesaglitazar  (ISO)
testosterone cypionate  (EXP)
tetrachloro-1,4-benzoquinone  (EXP)
tetrachloromethane  (EXP,ISO)
tetrahydrocurcumin  (EXP)
thiacloprid  (ISO)
thiamethoxam  (ISO)
thioacetamide  (EXP,ISO)
thymoquinone  (ISO)
thyroxine  (ISO)
titanium dioxide  (EXP,ISO)
tramadol  (ISO)
trans-caffeic acid  (EXP,ISO)
trelagliptin  (EXP)
trichloroethene  (EXP)
Triptolide  (EXP,ISO)
troglitazone  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
ursolic acid  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
vandetanib  (ISO)
verapamil  (ISO)
vildagliptin  (EXP)
vitamin D  (EXP)
vitamin E  (ISO)
vitamin K  (ISO)
zearalenone  (EXP)
zidovudine  (ISO)
zinc atom  (ISO)
zinc molecular entity  (ISO)
zinc oxide  (EXP,ISO)
zinc sulfate  (EXP)
zinc(0)  (ISO)
zolmitriptan  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
extracellular space  (IDA,ISO)

Molecular Function

References

References - curated
1. Al-Said MS, etal., Evid Based Complement Alternat Med. 2016;2016:1867048. doi: 10.1155/2016/1867048. Epub 2016 May 12.
2. Bu Y and Yu J, Zhonghua Yi Xue Za Zhi. 2015 Oct 20;95(39):3180-3.
3. Chen JY, etal., J Ethnopharmacol. 2012 Aug 1;142(3):811-8. doi: 10.1016/j.jep.2012.06.005. Epub 2012 Jun 15.
4. Cui X, etal., Afr J Tradit Complement Altern Med. 2016 Aug 12;13(5):114-122. doi: 10.21010/ajtcam.v13i5.15. eCollection 2016.
5. Guardiola Arévalo A, etal., Gastroenterol Hepatol. 2017 Feb;40(2):59-69. doi: 10.1016/j.gastrohep.2016.11.002. Epub 2016 Dec 20.
6. Guardiola-Arévalo A, etal., Gastroenterol Hepatol. 2018 Mar;41(3):153-162. doi: 10.1016/j.gastrohep.2017.11.003. Epub 2017 Dec 24.
7. Guijarro de Armas MG, etal., Med Clin (Barc). 2015 Jan 20;144(2):55-8. doi: 10.1016/j.medcli.2014.02.018. Epub 2014 Apr 24.
8. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
9. Kim HJ, etal., Korean J Intern Med. 2019 Jan 23. pii: kjim.2018.214. doi: 10.3904/kjim.2018.214.
10. Lima de Medeiros BJ, etal., Pharmacognosy Res. 2011 Apr;3(2):79-84. doi: 10.4103/0974-8490.81954.
11. Liu R, etal., Liver Int. 2009 Mar;29(3):337-43. doi: 10.1111/j.1478-3231.2008.01862.x. Epub 2008 Aug 14.
12. Mahale AR, etal., J Int Med Res. 2018 Nov;46(11):4447-4454. doi: 10.1177/0300060518793039. Epub 2018 Sep 5.
13. MGD data from the GO Consortium
14. Nishiura T, etal., J Anesth. 1994 Mar;8(1):87-92. doi: 10.1007/BF02482762.
15. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. Pagliarini R, etal., Cell Rep. 2016 Jun 7;15(10):2292-2300. doi: 10.1016/j.celrep.2016.05.014. Epub 2016 May 26.
17. Pipeline to import KEGG annotations from KEGG into RGD
18. Pipeline to import SMPDB annotations from SMPDB into RGD
19. Qian K, etal., Diabetes Metab Res Rev. 2015 Sep;31(6):562-71. doi: 10.1002/dmrr.2655. Epub 2015 Jun 17.
20. Rafter I, etal., Int J Mol Med. 2012 Nov;30(5):1241-9. doi: 10.3892/ijmm.2012.1106. Epub 2012 Aug 23.
21. RGD automated import pipeline
22. RGD automated import pipeline for gene-chemical interactions
23. Wei YL, etal., Braz J Med Biol Res. 2017 May 15;50(6):e5758. doi: 10.1590/1414-431X20175758.
24. Yang RZ, etal., Hepatology. 2009 Feb;49(2):598-607. doi: 10.1002/hep.22657.
Additional References at PubMed
PMID:849243   PMID:1311971   PMID:1685136   PMID:1975491   PMID:2165966   PMID:2272507   PMID:2880797   PMID:2882514   PMID:4077152   PMID:4747555   PMID:6980942   PMID:8563168  
PMID:9226373   PMID:9680378   PMID:10349636   PMID:10591541   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14681479   PMID:15122758   PMID:15306695   PMID:15489334  
PMID:15652761   PMID:16141072   PMID:16141073   PMID:19050265   PMID:20971848   PMID:21873635   PMID:22609950   PMID:22796562   PMID:24194600   PMID:29462428   PMID:32325033  


Genomics

Comparative Map Data
Gpt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,580,926 - 76,583,875 (+)NCBIGRCm39mm39
GRCm39 Ensembl1576,579,916 - 76,583,886 (+)Ensembl
GRCm381576,696,726 - 76,699,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,695,716 - 76,699,686 (+)EnsemblGRCm38mm10GRCm38
MGSCv371576,527,194 - 76,530,105 (+)NCBIGRCm37mm9NCBIm37
MGSCv361576,524,016 - 76,526,930 (+)NCBImm8
Celera1578,190,374 - 78,193,285 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.28NCBI
GPT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8144,502,973 - 144,507,174 (+)EnsemblGRCh38hg38GRCh38
GRCh388144,503,068 - 144,507,172 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378145,728,451 - 145,732,555 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,700,231 - 145,703,357 (+)NCBINCBI36hg18NCBI36
Build 348145,700,232 - 145,703,357NCBI
Celera8141,904,937 - 141,908,027 (+)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8140,842,619 - 140,845,709 (+)NCBIHuRef
CHM1_18145,767,740 - 145,770,746 (+)NCBICHM1_1
Gpt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27108,416,646 - 108,419,495 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7108,416,642 - 108,419,494 (+)Ensembl
Rnor_6.07117,759,083 - 117,761,932 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,759,083 - 117,761,931 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,745,308 - 117,749,938 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,746,054 - 114,748,903 (+)NCBIRGSC3.4rn4RGSC3.4
Celera7104,766,538 - 104,769,387 (+)NCBICelera
Cytogenetic Map7q34NCBI
Gpt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,127,997 - 3,132,459 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,127,997 - 3,132,459 (+)NCBIChiLan1.0ChiLan1.0
GPT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,923,757 - 37,927,843 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,924,422 - 37,926,156 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,884,479 - 37,888,507 (+)NCBI
ROS_Cfam_1.01338,397,476 - 38,401,488 (+)NCBI
UMICH_Zoey_3.11338,089,429 - 38,093,531 (+)NCBI
UNSW_CanFamBas_1.01338,197,829 - 38,201,856 (+)NCBI
UU_Cfam_GSD_1.01338,674,294 - 38,678,329 (+)NCBI
Gpt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303339,711 - 344,808 (-)NCBI
SpeTri2.0NW_0049364707,765,810 - 7,770,837 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4297,748 - 320,056 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14297,747 - 302,498 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24388,746 - 393,520 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,716,802 - 138,721,421 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,718,767 - 138,721,251 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660391,133,510 - 1,138,125 (-)NCBIVero_WHO_p1.0
Gpt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473512,355,476 - 12,359,910 (-)NCBIHetGla_female_1.0hetGla2


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined346021278717086Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined346021278717086Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined346021278717086Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15346021278717086Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15346021278717086Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15610000078800000Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15610000086800000Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156100000100900000Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15690000084700000Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927293679590561Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402117102988123Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800000102100000Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578270103517472Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800000086800000Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154230000095600000Mouse
1300644Fob3_mF-line obesity QTL 3 (mouse)11.3Not determined154414443889377036Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154468146478681588Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154498729278987432Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154651779780517996Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154651779780517996Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154743448581434630Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154753774781537842Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154850000098500000Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548500000101800000Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154859351382593647Mouse
1301779Dpml_mdopamine loss (mouse)Not determined155114129876910293Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155128885985288984Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155154651285546662Mouse
10412067Pain2_mpain 2 (mouse)Not determined155177349085773777Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155181398385822600Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155193466685934802Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155370000089700000Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155491728088917280Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556323312103517472Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155690000087800000Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155724515691245304Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155724515691245304Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156170000095700000Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156327970297279794Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156351779781202235Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564434485103517472Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156492762598927745Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156545237799456827Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156564117599641298Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567386497101386646Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570461452104043685Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570465070104043685Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570465070104043685Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572498466104043685Mouse
1300844Emo2_memotionality 2 (mouse)Not determined157250061076910293Mouse
1302002Cocia2_mcocaine induced activation 2 (mouse)Not determined157250061080014977Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573545941104043685Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157422869182789955Mouse
13442492Mecth2_mmechanosensation threshold 2 (mouse)157479100079503000Mouse
1301472Pain1_mpain 1 (mouse)Not determined157544899790928982Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:262
Count of miRNA genes:230
Interacting mature miRNAs:244
Transcripts:ENSMUST00000023203
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000023203   ⟹   ENSMUSP00000023203
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,580,933 - 76,583,886 (+)Ensembl
GRCm38.p6 Ensembl1576,696,733 - 76,699,686 (+)Ensembl
RefSeq Acc Id: ENSMUST00000228987
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,582,262 - 76,583,103 (+)Ensembl
GRCm38.p6 Ensembl1576,698,062 - 76,698,903 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229140   ⟹   ENSMUSP00000155686
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,582,411 - 76,583,848 (+)Ensembl
GRCm38.p6 Ensembl1576,698,211 - 76,699,648 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229340
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,580,936 - 76,583,848 (+)Ensembl
GRCm38.p6 Ensembl1576,696,736 - 76,699,648 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229679   ⟹   ENSMUSP00000155553
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,579,985 - 76,583,875 (+)Ensembl
GRCm38.p6 Ensembl1576,695,785 - 76,699,675 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229734   ⟹   ENSMUSP00000155491
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,580,946 - 76,583,775 (+)Ensembl
GRCm38.p6 Ensembl1576,696,746 - 76,699,575 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229856
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,580,966 - 76,583,848 (+)Ensembl
GRCm38.p6 Ensembl1576,696,766 - 76,699,648 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230283
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,580,936 - 76,583,875 (+)Ensembl
GRCm38.p6 Ensembl1576,696,736 - 76,699,675 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230482
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,580,932 - 76,583,874 (+)Ensembl
GRCm38.p6 Ensembl1576,696,732 - 76,699,674 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231028   ⟹   ENSMUSP00000155475
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,579,916 - 76,582,244 (+)Ensembl
GRCm38.p6 Ensembl1576,695,716 - 76,698,044 (+)Ensembl
RefSeq Acc Id: NM_182805   ⟹   NP_877957
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391576,580,926 - 76,583,875 (+)NCBI
GRCm381576,696,726 - 76,699,675 (+)NCBI
MGSCv371576,527,194 - 76,530,105 (+)RGD
Celera1578,190,374 - 78,193,285 (+)RGD
cM Map15 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_877957   ⟸   NM_182805
- UniProtKB: Q8QZR5 (UniProtKB/Swiss-Prot),   Q566C3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000155475   ⟸   ENSMUST00000231028
RefSeq Acc Id: ENSMUSP00000155491   ⟸   ENSMUST00000229734
RefSeq Acc Id: ENSMUSP00000155553   ⟸   ENSMUST00000229679
RefSeq Acc Id: ENSMUSP00000155686   ⟸   ENSMUST00000229140
RefSeq Acc Id: ENSMUSP00000023203   ⟸   ENSMUST00000023203
Protein Domains
Aminotran_1_2

Promoters
RGD ID:6849796
Promoter ID:EP59001
Type:single initiation site
Name:MM_GPT_5
Description:UDP-GlcNAc:dolichol phosphate N-acetylglucosamine-1-phosphatetransferase (GPT), DPAGT2 or GNPTA gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 233; Mouse GlcNAc-1-phosphate transferase
Alternative Promoters:alternative promoter #5 of 5; 5' exon 1; site 1; major promoter.; see alsoEP59005  EP59004  EP59003  EP59002  
Tissues & Cell Lines:housekeeping gene
Experiment Methods:Primer extension with homologous sequence ladder
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36Un1,377 - 1,437EPD
RGD ID:6826092
Promoter ID:MM_KWN:18903
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000023203,   UC007WLR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361576,526,376 - 76,527,312 (+)MPROMDB
RGD ID:8684152
Promoter ID:EPDNEW_M20107
Type:multiple initiation site
Name:Gpt_1
Description:Mus musculus glutamic pyruvic transaminase, soluble , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381576,696,733 - 76,696,793EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95802 AgrOrtholog
Ensembl Genes ENSMUSG00000022546 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000023203 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000155475 UniProtKB/TrEMBL
  ENSMUSP00000155491 UniProtKB/TrEMBL
  ENSMUSP00000155553 UniProtKB/Swiss-Prot
  ENSMUSP00000155686 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023203 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000229140 UniProtKB/TrEMBL
  ENSMUST00000229679 UniProtKB/Swiss-Prot
  ENSMUST00000229734 UniProtKB/TrEMBL
  ENSMUST00000231028 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aminotransferase_I/II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_dom1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:76282 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95802 ENTREZGENE
NCBI Gene 76282 ENTREZGENE
Pfam Aminotran_1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GPT RGD
PhenoGen Gpt PhenoGen
Superfamily-SCOP SSF53383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VHV7_MOUSE UniProtKB/TrEMBL
  A0A2R8VHW0_MOUSE UniProtKB/TrEMBL
  A0A2R8VI31_MOUSE UniProtKB/TrEMBL
  ALAT1_MOUSE UniProtKB/Swiss-Prot
  Q566C3 ENTREZGENE, UniProtKB/TrEMBL
  Q8QZR5 ENTREZGENE