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Gene: Txnrd1 (thioredoxin reductase 1) Mus musculus
Symbol: Txnrd1
Name: thioredoxin reductase 1
Description: Exhibits thioredoxin-disulfide reductase activity. Involved in cell population proliferation and mesoderm formation. Localizes to the cytosol and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is expressed in several structures, including alimentary system; integumental system; musculoskeletal system; nervous system; and sensory organ. Orthologous to human TXNRD1 (thioredoxin reductase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: thioredoxin reductase 1, cytoplasmic; thioredoxin reductase TR1; TR; TR alpha; TR1; TrxR1
Homo sapiens (human) : TXNRD1 (thioredoxin reductase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Txnrd1 (thioredoxin reductase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txnrd1 (thioredoxin reductase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TXNRD1 (thioredoxin reductase 1)
Canis lupus familiaris (dog) : TXNRD1 (thioredoxin reductase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txnrd1 (thioredoxin reductase 1)
Sus scrofa (pig) : TXNRD1 (thioredoxin reductase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381082,833,951 - 82,897,724 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371082,296,696 - 82,360,469 (+)NCBIGRCm37mm9NCBIm37
MGSCv361082,288,978 - 82,327,511 (+)NCBImm8
Celera1084,818,861 - 84,882,466 (+)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Txnrd1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62252
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.