Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Txnrd1 (thioredoxin reductase 1) Mus musculus
Symbol: Txnrd1
Name: thioredoxin reductase 1
RGD ID: 62252
Description: Exhibits thioredoxin-disulfide reductase activity. Involved in cell population proliferation and mesoderm formation. Localizes to cytosol and nucleus. Is expressed in several structures, including alimentary system; integumental system; musculoskeletal system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human TXNRD1 (thioredoxin reductase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: T; thioredoxin reductase 1, cytoplasmic; thioredoxin reductase TR1; TR; TR alpha; TR1; Trx; TrxR1
Homo sapiens (human) : TXNRD1 (thioredoxin reductase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Txnrd1 (thioredoxin reductase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txnrd1 (thioredoxin reductase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100977237 (thioredoxin reductase 1, cytoplasmic)
Canis lupus familiaris (dog) : TXNRD1 (thioredoxin reductase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txnrd1 (thioredoxin reductase 1)
Sus scrofa (pig) : TXNRD1 (thioredoxin reductase 1)
Chlorocebus sabaeus (African green monkey) : TXNRD1 (thioredoxin reductase 1)
Heterocephalus glaber (naked mole-rat) : Txnrd1 (thioredoxin reductase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391082,669,785 - 82,733,558 (+)NCBI
GRCm381082,833,951 - 82,897,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1082,833,951 - 82,897,712 (+)EnsemblGRCm38mm10GRCm38
MGSCv371082,296,696 - 82,360,469 (+)NCBIGRCm37mm9NCBIm37
MGSCv361082,288,978 - 82,327,511 (+)NCBImm8
Celera1084,818,861 - 84,882,466 (+)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Txnrd1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62252
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.