Spc25 (SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)) - Rat Genome Database

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Gene: Spc25 (SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)) Mus musculus
Analyze
Symbol: Spc25
Name: SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
RGD ID: 1623224
MGI Page MGI
Description: Predicted to be involved in attachment of spindle microtubules to kinetochore and mitotic spindle organization. Predicted to act upstream of or within cell division. Predicted to be located in cytosol and kinetochore. Predicted to be part of Ndc80 complex. Is expressed in several structures, including brain; nephrogenic zone; retina; and ventral grey horn. Orthologous to human SPC25 (SPC25 component of NDC80 kinetochore complex).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 2600017H08Rik; 2610205L13Rik; kinetochore protein Spc25; Spbc; Spbc25; spindle pole body component 25 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39269,009,753 - 69,036,583 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl269,024,239 - 69,036,538 (-)EnsemblGRCm39 Ensembl
GRCm38269,193,895 - 69,206,213 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl269,193,895 - 69,206,194 (-)EnsemblGRCm38mm10GRCm38
MGSCv37269,031,953 - 69,044,214 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36268,994,735 - 69,006,996 (-)NCBIMGSCv36mm8
Celera270,859,628 - 70,872,362 (-)NCBICelera
Cytogenetic Map2C2NCBI
cM Map239.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-methylcholanthrene  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
amitrole  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
Benzo[k]fluoranthene  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
chrysene  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (EXP)
Enterolactone  (ISO)
epoxiconazole  (EXP)
erythromycin estolate  (ISO)
ethanol  (EXP)
fenpyroximate  (ISO)
fipronil  (ISO)
folic acid  (ISO)
furan  (ISO)
gentamycin  (ISO)
glycidol  (ISO)
glycine betaine  (ISO)
indole-3-methanol  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
lidocaine  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
lucanthone  (ISO)
methamphetamine  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mitomycin C  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
palbociclib  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
PhIP  (ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tebufenpyrad  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (EXP)
trovafloxacin  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15226823   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:18270576   PMID:18455984   PMID:18799693   PMID:20436479   PMID:21084868   PMID:21267068   PMID:21440680   PMID:21677750   PMID:21873635   PMID:23258294   PMID:23418356   PMID:26410627  
PMID:28535371   PMID:32554809   PMID:33798452   PMID:34972250  


Genomics

Comparative Map Data
Spc25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39269,009,753 - 69,036,583 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl269,024,239 - 69,036,538 (-)EnsemblGRCm39 Ensembl
GRCm38269,193,895 - 69,206,213 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl269,193,895 - 69,206,194 (-)EnsemblGRCm38mm10GRCm38
MGSCv37269,031,953 - 69,044,214 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36268,994,735 - 69,006,996 (-)NCBIMGSCv36mm8
Celera270,859,628 - 70,872,362 (-)NCBICelera
Cytogenetic Map2C2NCBI
cM Map239.64NCBI
SPC25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382168,861,521 - 168,890,430 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2168,834,132 - 168,913,371 (-)EnsemblGRCh38hg38GRCh38
GRCh372169,727,401 - 169,746,940 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362169,435,647 - 169,455,190 (-)NCBINCBI36Build 36hg18NCBI36
Celera2163,352,703 - 163,372,246 (-)NCBICelera
Cytogenetic Map2q24.3NCBI
HuRef2161,623,412 - 161,643,117 (-)NCBIHuRef
CHM1_12169,733,212 - 169,752,754 (-)NCBICHM1_1
T2T-CHM13v2.02169,319,011 - 169,364,874 (-)NCBIT2T-CHM13v2.0
Spc25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8374,337,872 - 74,396,825 (-)NCBIGRCr8
mRatBN7.2353,930,013 - 53,988,940 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl353,975,704 - 53,988,959 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx357,376,126 - 57,389,267 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0365,959,682 - 65,972,823 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0363,721,842 - 63,735,020 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0355,438,534 - 55,451,961 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl355,438,536 - 55,451,798 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0362,050,000 - 62,063,404 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4351,361,185 - 51,374,357 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1351,257,558 - 51,270,729 (-)NCBI
Celera353,537,785 - 53,550,955 (-)NCBICelera
Cytogenetic Map3q21NCBI
Spc25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554495,533,450 - 5,557,835 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554495,533,464 - 5,556,341 (+)NCBIChiLan1.0ChiLan1.0
SPC25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21371,532,236 - 71,574,186 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B71,547,209 - 71,589,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B56,148,325 - 56,190,851 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B173,613,457 - 173,632,947 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B173,613,457 - 173,655,791 (-)Ensemblpanpan1.1panPan2
SPC25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13613,697,389 - 13,710,367 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3613,697,456 - 13,710,635 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3613,708,404 - 13,721,357 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03613,813,505 - 13,826,418 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3613,813,585 - 13,826,318 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13613,898,536 - 13,911,444 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03613,885,686 - 13,899,255 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03613,999,234 - 14,012,225 (-)NCBIUU_Cfam_GSD_1.0
Spc25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303130,965,506 - 130,989,530 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646910,628,230 - 10,652,232 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646910,628,235 - 10,652,168 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPC25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1575,336,514 - 75,371,277 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11575,339,171 - 75,371,275 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21584,441,925 - 84,474,848 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPC25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11054,390,300 - 54,423,478 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1054,403,157 - 54,423,245 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040145,110,045 - 145,152,265 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spc25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247876,608,039 - 6,624,597 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247876,608,403 - 6,624,533 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Spc25
950 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:914
Count of miRNA genes:325
Interacting mature miRNAs:358
Transcripts:ENSMUST00000005365, ENSMUST00000112320, ENSMUST00000126638, ENSMUST00000127243, ENSMUST00000149045, ENSMUST00000149401, ENSMUST00000149643, ENSMUST00000150505, ENSMUST00000167875
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3579732469797406Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3579732469797406Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3579732469797406Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23599167971609412Mouse
11038703Ltpr1_mLeishmania tropica response 1 (mouse)23997166573971811Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1301480Pbwg1_mpostnatal body weight growth 1 (mouse)Not determined24182071975820843Mouse
4141069Pbwg1.5_mpostnatal body weight growth 1.5 (mouse)Not determined4352061277520756Mouse
1300788Cia2_mcollagen induced arthritis QTL 2 (mouse)Not determined24352061277520756Mouse
1300671Cia4_mcollagen induced arthritis QTL 4 (mouse)Not determined24352061277520756Mouse
1301402Ap2q_malcohol preference 2 QTL (mouse)Not determined24352061277520756Mouse
1301411Pitm1_mprion incubation time 1 (mouse)Not determined24352061277520756Mouse
10755532Lymph5_mlymphocyte differential 5 (mouse)24419901778199017Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11532740Pbwg1.10_mpostnatal body weight growth 1.10 (mouse)24813241282132495Mouse
1558820Moo1_mmodifier of Odc1 (mouse)Not determined174826974682269934Mouse
1301747Eae21_mexperimental allergic encephalomyelitis 21 (mouse)Not determined24826974682269934Mouse
1301235Alcw4_malcohol withdrawal 4 (mouse)Not determined24826974682269934Mouse
1300568Hdl1_mhigh density lipoprotein (HDL) level 1 (mouse)Not determined24826974682269934Mouse
10755526Lymph1_mlymphocyte differential 1 (mouse)25081931484819314Mouse
1300875Taste1_mtaste-saccharin preference 1 (mouse)Not determined25092317584923278Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25170327685703425Mouse
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse
13432184Actdes1_mactivity chamber total difference ethanol/saline 1 (mouse)25939228769292287Mouse
13432174Actres5_mactivity response to ethanol/saline 5 (mouse)25989228769792287Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
13432178Actres2_mactivity response to ethanol/saline 2 (mouse)26069228774092287Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301059Hrtfm1_mheart failure modifier 1 (mouse)Not determined26759194074964933Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse

Markers in Region
UniSTS:234414  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38269,193,996 - 69,194,159UniSTSGRCm38
MGSCv37269,032,053 - 69,032,216UniSTSGRCm37
Celera270,859,728 - 70,859,891UniSTS
Cytogenetic Map2C3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001199123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001305800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_025565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006500003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK003408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL929221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ086993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX222514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000005365   ⟹   ENSMUSP00000005365
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,024,239 - 69,036,538 (-)Ensembl
GRCm38.p6 Ensembl269,193,895 - 69,206,194 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112320   ⟹   ENSMUSP00000107939
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,024,239 - 69,036,479 (-)Ensembl
GRCm38.p6 Ensembl269,193,895 - 69,206,135 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126638
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,028,991 - 69,036,467 (-)Ensembl
GRCm38.p6 Ensembl269,198,647 - 69,206,123 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127243   ⟹   ENSMUSP00000120142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,024,239 - 69,036,501 (-)Ensembl
GRCm38.p6 Ensembl269,193,895 - 69,206,157 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149045   ⟹   ENSMUSP00000120999
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,027,491 - 69,035,474 (-)Ensembl
GRCm38.p6 Ensembl269,197,147 - 69,205,130 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149401
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,030,267 - 69,035,559 (-)Ensembl
GRCm38.p6 Ensembl269,199,923 - 69,205,215 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149643   ⟹   ENSMUSP00000117415
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,027,534 - 69,036,524 (-)Ensembl
GRCm38.p6 Ensembl269,197,190 - 69,206,180 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150505
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,035,982 - 69,036,523 (-)Ensembl
GRCm38.p6 Ensembl269,205,638 - 69,206,179 (-)Ensembl
RefSeq Acc Id: ENSMUST00000167875   ⟹   ENSMUSP00000128039
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl269,024,240 - 69,036,534 (-)Ensembl
GRCm38.p6 Ensembl269,193,896 - 69,206,190 (-)Ensembl
RefSeq Acc Id: NM_001199123   ⟹   NP_001186052
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39269,024,239 - 69,036,557 (-)NCBI
GRCm38269,193,895 - 69,206,213 (-)NCBI
Celera270,859,627 - 70,872,395 (-)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001199124   ⟹   NP_001186053
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39269,024,239 - 69,036,557 (-)NCBI
GRCm38269,193,895 - 69,206,213 (-)NCBI
Celera270,859,627 - 70,872,395 (-)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001305800   ⟹   NP_001292729
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39269,024,239 - 69,036,557 (-)NCBI
GRCm38269,193,895 - 69,206,213 (-)NCBI
Sequence:
RefSeq Acc Id: NM_025565   ⟹   NP_079841
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39269,024,239 - 69,036,557 (-)NCBI
GRCm38269,193,895 - 69,206,213 (-)NCBI
MGSCv37269,031,953 - 69,044,214 (-)RGD
Celera270,859,627 - 70,872,395 (-)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006500003   ⟹   XP_006500066
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39269,024,239 - 69,036,556 (-)NCBI
GRCm38269,193,895 - 69,206,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162450   ⟹   XP_036018343
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39269,024,239 - 69,036,556 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162451   ⟹   XP_036018344
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39269,009,753 - 69,036,583 (-)NCBI
Sequence:
RefSeq Acc Id: NP_079841   ⟸   NM_025565
- Peptide Label: isoform 2
- UniProtKB: A2AUT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186053   ⟸   NM_001199124
- Peptide Label: isoform 1
- UniProtKB: Q9D021 (UniProtKB/Swiss-Prot),   Q9D1K6 (UniProtKB/Swiss-Prot),   Q3UA16 (UniProtKB/Swiss-Prot),   A2AUT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186052   ⟸   NM_001199123
- Peptide Label: isoform 1
- UniProtKB: Q9D021 (UniProtKB/Swiss-Prot),   Q9D1K6 (UniProtKB/Swiss-Prot),   Q3UA16 (UniProtKB/Swiss-Prot),   A2AUT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006500066   ⟸   XM_006500003
- Peptide Label: isoform X1
- UniProtKB: Q9D021 (UniProtKB/Swiss-Prot),   Q9D1K6 (UniProtKB/Swiss-Prot),   Q3UA16 (UniProtKB/Swiss-Prot),   A2AUT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001292729   ⟸   NM_001305800
- Peptide Label: isoform 1
- UniProtKB: Q9D021 (UniProtKB/Swiss-Prot),   Q9D1K6 (UniProtKB/Swiss-Prot),   Q3UA16 (UniProtKB/Swiss-Prot),   A2AUT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000120142   ⟸   ENSMUST00000127243
RefSeq Acc Id: ENSMUSP00000107939   ⟸   ENSMUST00000112320
RefSeq Acc Id: ENSMUSP00000117415   ⟸   ENSMUST00000149643
RefSeq Acc Id: ENSMUSP00000120999   ⟸   ENSMUST00000149045
RefSeq Acc Id: ENSMUSP00000128039   ⟸   ENSMUST00000167875
RefSeq Acc Id: ENSMUSP00000005365   ⟸   ENSMUST00000005365
RefSeq Acc Id: XP_036018344   ⟸   XM_036162451
- Peptide Label: isoform X2
- UniProtKB: A2AUT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036018343   ⟸   XM_036162450
- Peptide Label: isoform X1
- UniProtKB: Q9D021 (UniProtKB/Swiss-Prot),   Q3UA16 (UniProtKB/Swiss-Prot),   Q9D1K6 (UniProtKB/Swiss-Prot),   A2AUT4 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UA16-F1-model_v2 AlphaFold Q3UA16 1-226 view protein structure

Promoters
RGD ID:6832819
Promoter ID:MM_KWN:29531
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   ES_Cell
Transcripts:OTTMUST00000031232,   OTTMUST00000031233
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36269,043,131 - 69,044,267 (-)MPROMDB
RGD ID:6832817
Promoter ID:MM_KWN:29532
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   MEF_B4,   Spleen
Transcripts:ENSMUST00000112320,   OTTMUST00000031226,   OTTMUST00000031227,   OTTMUST00000031230,   OTTMUST00000031231,   UC008JXX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36269,043,934 - 69,044,434 (-)MPROMDB
RGD ID:6877490
Promoter ID:EPDNEW_M2195
Type:initiation region
Name:Spc25_1
Description:Mus musculus SPC25, NDC80 kinetochore complex component, homolog, transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38269,206,157 - 69,206,217EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913692 AgrOrtholog
Ensembl Genes ENSMUSG00000005233 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000005365 ENTREZGENE
  ENSMUST00000005365.15 UniProtKB/Swiss-Prot
  ENSMUST00000112320 ENTREZGENE
  ENSMUST00000112320.8 UniProtKB/Swiss-Prot
  ENSMUST00000127243.8 UniProtKB/TrEMBL
  ENSMUST00000149045.8 UniProtKB/TrEMBL
  ENSMUST00000149643.2 UniProtKB/TrEMBL
  ENSMUST00000167875 ENTREZGENE
  ENSMUST00000167875.9 UniProtKB/Swiss-Prot
Gene3D-CATH 6.10.250.1950 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Spc25 UniProtKB/Swiss-Prot
  Spc25 UniProtKB/Swiss-Prot
  Spc25 UniProtKB/TrEMBL
  Spc25 UniProtKB/TrEMBL
KEGG Report mmu:66442 UniProtKB/Swiss-Prot
MGD MGI:1913692 ENTREZGENE
NCBI Gene 66442 ENTREZGENE
PANTHER KINETOCHORE PROTEIN SPC25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Spindle_Spc25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Spc25 PhenoGen
UniProt A2AUT1_MOUSE UniProtKB/TrEMBL
  A2AUT3 ENTREZGENE, UniProtKB/TrEMBL
  A2AUT4 ENTREZGENE, UniProtKB/TrEMBL
  Q3UA16 ENTREZGENE
  Q9D021 ENTREZGENE
  Q9D1K6 ENTREZGENE
  SPC25_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9D021 UniProtKB/Swiss-Prot
  Q9D1K6 UniProtKB/Swiss-Prot