Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gsr (glutathione reductase) Mus musculus
Analyze
Symbol: Gsr
Name: glutathione reductase
RGD ID: 732222
Description: Exhibits glutathione-disulfide reductase activity. Predicted to be involved in several processes, including cell redox homeostasis; glutathione metabolic process; and spermatogenesis. Localizes to external side of plasma membrane. Is expressed in brain ventricular layer; gut; lung; metanephros; and retina. Human ortholog(s) of this gene implicated in cataract and macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; glutathione metabolic pathway; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (RS)-coclaurine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI325518; D8Ertd238; D8Ertd238e; glutathione reductase 1; glutathione reductase, mitochondrial; GR; Gr-; Gr-1; Gr1; GRase
Orthologs:
Homo sapiens (human) : GSR (glutathione-disulfide reductase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gsr (glutathione-disulfide reductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsr (glutathione-disulfide reductase)
Pan paniscus (bonobo/pygmy chimpanzee) : GSR (glutathione-disulfide reductase)
Canis lupus familiaris (dog) : GSR (glutathione-disulfide reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsr (glutathione-disulfide reductase)
Sus scrofa (pig) : GSR (glutathione-disulfide reductase)
Chlorocebus sabaeus (African green monkey) : GSR (glutathione-disulfide reductase)
Heterocephalus glaber (naked mole-rat) : Gsr (glutathione-disulfide reductase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl833,652,523 - 33,698,163 (+)EnsemblGRCm38mm10GRCm38
GRCm38833,653,238 - 33,698,162 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37834,763,710 - 34,808,634 (+)NCBIGRCm37mm9NCBIm37
MGSCv36832,569,577 - 32,614,657 (+)NCBImm8
MGSCv36835,119,173 - 35,164,097 (+)NCBImm8
Celera836,289,529 - 36,337,457 (+)NCBICelera
Cytogenetic Map8A3NCBI
cM Map820.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gsr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732222
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.