Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rxra (retinoid X receptor alpha) Mus musculus
Symbol: Rxra
Name: retinoid X receptor alpha
Description: Exhibits DNA binding activity; nuclear receptor activity; and transcription factor binding activity. Contributes to transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; regulation of branching involved in prostate gland morphogenesis; and regulation of cellular macromolecule biosynthetic process. Localizes to the RNA polymerase II transcription factor complex. Used to study congenital heart disease; dilated cardiomyopathy; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and sensory organ. Orthologous to human RXRA (retinoid X receptor alpha); PARTICIPATES IN retinoic acid signaling pathway; bile acid transport pathway; hepatitis C pathway; INTERACTS WITH (-)-anisomycin; 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9530071D11Rik; Nr2b1; nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; RXR alpha 1; RXRalpha1
Homo sapiens (human) : RXRA (retinoid X receptor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rxra (retinoid X receptor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rxra (retinoid X receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : RXRA (retinoid X receptor alpha)
Canis lupus familiaris (dog) : RXRA (retinoid X receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rxra (retinoid X receptor alpha)
Sus scrofa (pig) : RXRA (retinoid X receptor alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38227,676,445 - 27,763,319 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37227,532,721 - 27,618,839 (+)NCBIGRCm37mm9NCBIm37
MGSCv36227,499,210 - 27,585,328 (+)NCBImm8
Celera227,439,800 - 27,465,824 (+)NCBICelera
Cytogenetic Map2 A3NCBI
cM Map219.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rxra
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11250
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.