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Gene: Rxra (retinoid X receptor alpha) Mus musculus
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Symbol: Rxra
Name: retinoid X receptor alpha
Description: Exhibits DNA binding activity; nuclear receptor activity; and transcription factor binding activity. Contributes to transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; regulation of branching involved in prostate gland morphogenesis; and regulation of cellular macromolecule biosynthetic process. Localizes to the RNA polymerase II transcription factor complex. Used to study congenital heart disease; dilated cardiomyopathy; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and sensory organ. Orthologous to human RXRA (retinoid X receptor alpha); PARTICIPATES IN retinoic acid signaling pathway; bile acid transport pathway; hepatitis C pathway; INTERACTS WITH (-)-anisomycin; 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9530071D11Rik; Nr2b1; nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; RXR alpha 1; RXRalpha1
Orthologs:
Homo sapiens (human) : RXRA (retinoid X receptor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rxra (retinoid X receptor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rxra (retinoid X receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : RXRA (retinoid X receptor alpha)
Canis lupus familiaris (dog) : RXRA (retinoid X receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rxra (retinoid X receptor alpha)
Sus scrofa (pig) : RXRA (retinoid X receptor alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38227,676,445 - 27,763,319 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37227,532,721 - 27,618,839 (+)NCBIGRCm37mm9NCBIm37
MGSCv36227,499,210 - 27,585,328 (+)NCBImm8
Celera227,439,800 - 27,465,824 (+)NCBICelera
Cytogenetic Map2 A3NCBI
cM Map219.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rxra
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11250
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.