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Gene: Maob (monoamine oxidase B) Mus musculus
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Symbol: Maob
Name: monoamine oxidase B
Description: Predicted to have flavin adenine dinucleotide binding activity; identical protein binding activity; and primary amine oxidase activity. Predicted to be involved in negative regulation of serotonin secretion; neurotransmitter catabolic process; and positive regulation of dopamine metabolic process. Localizes to mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human MAOB (monoamine oxidase B); PARTICIPATES IN citalopram pharmacodynamics pathway; citalopram pharmacokinetics pathway; Parkinson's disease pathway; INTERACTS WITH (+)-dexrazoxane; (-)-selegiline; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330414K01Rik; amine oxidase [flavin-containing] B; MAO-B; monoamine oxidase type B
Orthologs:
Homo sapiens (human) : MAOB (monoamine oxidase B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Maob (monoamine oxidase B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Maob (monoamine oxidase B)
Pan paniscus (bonobo/pygmy chimpanzee) : MAOB (monoamine oxidase B)
Canis lupus familiaris (dog) : MAOB (monoamine oxidase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Maob (monoamine oxidase B)
Sus scrofa (pig) : MAOB (monoamine oxidase B)
Chlorocebus sabaeus (African green monkey) : MAOB (monoamine oxidase B)
Heterocephalus glaber (naked mole-rat) : Maob (monoamine oxidase B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX16,709,282 - 16,817,366 (-)EnsemblGRCm38mm10GRCm38
GRCm38X16,709,281 - 16,817,366 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X16,286,407 - 16,394,492 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X15,866,241 - 15,974,323 (-)NCBImm8
CeleraX14,324,831 - 14,433,074 (-)NCBICelera
Cytogenetic MapXA1.2NCBI
cM MapX11.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Maob
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732581
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.