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Gene: Maob (monoamine oxidase B) Mus musculus
Symbol: Maob
Name: monoamine oxidase B
Description: Predicted to have flavin adenine dinucleotide binding activity; identical protein binding activity; and primary amine oxidase activity. Predicted to be involved in negative regulation of serotonin secretion; neurotransmitter catabolic process; and positive regulation of dopamine metabolic process. Localizes to mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human MAOB (monoamine oxidase B); PARTICIPATES IN citalopram pharmacodynamics pathway; citalopram pharmacokinetics pathway; Parkinson's disease pathway; INTERACTS WITH (+)-dexrazoxane; (-)-selegiline; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330414K01Rik; amine oxidase [flavin-containing] B; MAO-B; monoamine oxidase type B
Homo sapiens (human) : MAOB (monoamine oxidase B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Maob (monoamine oxidase B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Maob (monoamine oxidase B)
Pan paniscus (bonobo/pygmy chimpanzee) : MAOB (monoamine oxidase B)
Canis lupus familiaris (dog) : MAOB (monoamine oxidase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Maob (monoamine oxidase B)
Sus scrofa (pig) : MAOB (monoamine oxidase B)
Chlorocebus sabaeus (African green monkey) : MAOB (monoamine oxidase B)
Heterocephalus glaber (naked mole-rat) : Maob (monoamine oxidase B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 EnsemblX16,709,282 - 16,817,366 (-)EnsemblGRCm38mm10GRCm38
GRCm38X16,709,281 - 16,817,366 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X16,286,407 - 16,394,492 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X15,866,241 - 15,974,323 (-)NCBImm8
CeleraX14,324,831 - 14,433,074 (-)NCBICelera
Cytogenetic MapXA1.2NCBI
cM MapX11.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Maob
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732581
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.