Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cyp7a1 (cytochrome P450, family 7, subfamily a, polypeptide 1) Mus musculus
Analyze
Symbol: Cyp7a1
Name: cytochrome P450, family 7, subfamily a, polypeptide 1
Description: Exhibits cholesterol 7-alpha-monooxygenase activity. Involved in cholesterol catabolic process. Predicted to localize to the intracellular membrane-bounded organelle. Is expressed in liver. Orthologous to human CYP7A1 (cytochrome P450 family 7 subfamily A member 1); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dichloroethane; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 24-hydroxycholesterol 7-alpha-hydroxylase; cholesterol 7 alpha hydroxylase; cholesterol 7-alpha-hydroxylase; cholesterol 7-alpha-monooxygenase; CYPVII; CYPVIIc; cytochrome P450 7A1; cytochrome P450, 7a1
Orthologs:
Homo sapiens (human) : CYP7A1 (cytochrome P450 family 7 subfamily A member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyp7a1 (cytochrome P450 family 7 subfamily A member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102008593 (cholesterol 7-alpha-monooxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100991402 (cholesterol 7-alpha-monooxygenase)
Canis lupus familiaris (dog) : CYP7A1 (cytochrome P450 family 7 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101970910 (cholesterol 7-alpha-monooxygenase)
Sus scrofa (pig) : CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3846,265,612 - 6,275,632 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3746,192,759 - 6,202,778 (-)NCBIGRCm37mm9NCBIm37
MGSCv3646,192,759 - 6,202,778 (-)NCBImm8
Celera46,185,007 - 6,195,027 (-)NCBICelera
Cytogenetic Map4 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cyp7a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10458
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.