Uhrf1 (ubiquitin-like, containing PHD and RING finger domains, 1) - Rat Genome Database

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Gene: Uhrf1 (ubiquitin-like, containing PHD and RING finger domains, 1) Mus musculus
Analyze
Symbol: Uhrf1
Name: ubiquitin-like, containing PHD and RING finger domains, 1
RGD ID: 1332040
MGI Page MGI
Description: Enables several functions, including hemi-methylated DNA-binding activity; histone H3 ubiquitin ligase activity; and identical protein binding activity. Involved in negative regulation of gene expression via CpG island methylation and negative regulation of transcription by RNA polymerase II. Located in nuclear matrix and replication fork. Part of heterochromatin. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hindlimb phalanx; and sensory organ. Orthologous to human UHRF1 (ubiquitin like with PHD and ring finger domains 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AL022808; E3 ubiquitin-protein ligase UHRF1; ICBP; ICBP90; mUhrf1; Np; Np95; nuclear protein 95; nuclear zinc finger protein Np95; RING-type E3 ubiquitin transferase UHRF1; RNF106; ubiquitin-like PHD and RING finger domain-containing protein 1; ubiquitin-like-containing PHD and RING finger domains protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm15953   Gm5648  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,610,405 - 56,630,486 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,610,321 - 56,630,486 (+)EnsemblGRCm39 Ensembl
GRCm381756,303,337 - 56,323,486 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,303,321 - 56,323,486 (+)EnsemblGRCm38mm10GRCm38
MGSCv371756,442,760 - 56,462,909 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,937,126 - 55,957,195 (+)NCBIMGSCv36mm8
Celera1760,657,174 - 60,672,221 (+)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxynon-2-enal  (EXP)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
AM-251  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
auraptene  (ISO)
azoxystrobin  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
boron nitride  (ISO)
C60 fullerene  (ISO)
caffeine  (ISO)
Calcimycin  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (EXP)
deguelin  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP)
dichloroacetic acid  (EXP)
diethyl maleate  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
folic acid  (EXP,ISO)
fonofos  (ISO)
FR900359  (ISO)
fructose  (EXP)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glucose  (EXP)
glycerol 2-phosphate  (ISO)
glyphosate  (EXP)
hydroquinone  (ISO)
imiquimod  (EXP)
indole-3-methanol  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
MeIQx  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
palbociclib  (ISO)
paracetamol  (ISO)
parathion  (ISO)
PCB138  (EXP)
pentachlorophenol  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phytoestrogen  (ISO)
pirinixic acid  (EXP)
plumbagin  (ISO)
progesterone  (EXP)
propofol  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
sunitinib  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP,ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zaragozic acid A  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IDA,ISO)
cytosol  (TAS)
euchromatin  (ISO)
heterochromatin  (IDA,ISO)
nuclear matrix  (IDA)
nucleoplasm  (ISO,TAS)
nucleus  (IDA,ISO,TAS)
replication fork  (IDA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. On how mammalian transcription factors recognize methylated DNA. Buck-Koehntop BA and Defossez PA, Epigenetics. 2013 Feb;8(2):131-7. doi: 10.4161/epi.23632. Epub 2013 Jan 16.
2. Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation. Fujimori A, etal., Mamm Genome 1998 Dec;9(12):1032-5.
3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Tudor: a versatile family of histone methylation 'readers'. Lu R and Wang GG, Trends Biochem Sci. 2013 Nov;38(11):546-55. doi: 10.1016/j.tibs.2013.08.002. Epub 2013 Sep 10.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. Readout of epigenetic modifications. Patel DJ and Wang Z, Annu Rev Biochem. 2013;82:81-118. doi: 10.1146/annurev-biochem-072711-165700.
10. Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization. Powles N, etal., Dev Biol 2004 Apr 1;268(1):24-38.
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis. Walter A, etal., FASEB J. 2010 Sep;24(9):3360-9. doi: 10.1096/fj.09-149419. Epub 2010 May 4.
14. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:7671812   PMID:8634372   PMID:10349636   PMID:10512203   PMID:10984098   PMID:11042159   PMID:11076861   PMID:11161719   PMID:12058012   PMID:12084726   PMID:12477932   PMID:12520002  
PMID:12904583   PMID:14610273   PMID:14681479   PMID:14741369   PMID:14993289   PMID:15361834   PMID:15489334   PMID:15782199   PMID:15840001   PMID:16141072   PMID:16141073   PMID:17065439  
PMID:17182844   PMID:17673620   PMID:17967808   PMID:17994007   PMID:18287559   PMID:18508923   PMID:18692478   PMID:18772888   PMID:18772891   PMID:18799693   PMID:19056828   PMID:19077538  
PMID:19798101   PMID:20059953   PMID:20412781   PMID:20613874   PMID:21267068   PMID:21268065   PMID:21425081   PMID:21489993   PMID:21589869   PMID:21677750   PMID:21873635   PMID:22064703  
PMID:23463006   PMID:23754744   PMID:23825703   PMID:24013172   PMID:24025402   PMID:24253042   PMID:24368767   PMID:24777532   PMID:24782312   PMID:24818710   PMID:25358258   PMID:25451918  
PMID:25680957   PMID:25900245   PMID:26576615   PMID:26764384   PMID:27045799   PMID:27050515   PMID:27151458   PMID:27489107   PMID:27798843   PMID:27886214   PMID:27956603   PMID:28334952  
PMID:28604677   PMID:28705898   PMID:28712289   PMID:28976982   PMID:29055779   PMID:29180567   PMID:29471350   PMID:29558369   PMID:29618490   PMID:29859850   PMID:29968706   PMID:29999568  
PMID:30389914   PMID:30392929   PMID:30487604   PMID:30530687   PMID:30995416   PMID:31024001   PMID:31515281   PMID:31611260   PMID:31624244   PMID:32081844   PMID:32084194   PMID:32098917  
PMID:32325033   PMID:32358021   PMID:32609811   PMID:32897881   PMID:32927122   PMID:33058714   PMID:33359809   PMID:33568199   PMID:33616624   PMID:33634103   PMID:33744855   PMID:33938913  
PMID:33998651   PMID:34516921   PMID:34561619   PMID:35243267   PMID:35284939   PMID:35324392   PMID:35440090   PMID:35472067   PMID:35905740   PMID:36056023   PMID:36166308   PMID:36420895  
PMID:36539615   PMID:37225425   PMID:37407562   PMID:37414952   PMID:37493331   PMID:38060382   PMID:38335290  


Genomics

Comparative Map Data
Uhrf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,610,405 - 56,630,486 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,610,321 - 56,630,486 (+)EnsemblGRCm39 Ensembl
GRCm381756,303,337 - 56,323,486 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,303,321 - 56,323,486 (+)EnsemblGRCm38mm10GRCm38
MGSCv371756,442,760 - 56,462,909 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,937,126 - 55,957,195 (+)NCBIMGSCv36mm8
Celera1760,657,174 - 60,672,221 (+)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.26NCBI
UHRF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,903,080 - 4,962,154 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,903,080 - 4,962,154 (+)EnsemblGRCh38hg38GRCh38
GRCh37194,903,092 - 4,962,165 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,860,510 - 4,913,165 (+)NCBINCBI36Build 36hg18NCBI36
Build 34194,861,813 - 4,913,162NCBI
Celera194,846,530 - 4,899,186 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,671,491 - 4,723,801 (+)NCBIHuRef
CHM1_1194,909,372 - 4,962,038 (+)NCBICHM1_1
T2T-CHM13v2.0194,888,314 - 4,947,375 (+)NCBIT2T-CHM13v2.0
Uhrf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,220,162 - 1,241,792 (+)NCBIGRCr8
mRatBN7.291,133,117 - 1,154,639 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,134,909 - 1,154,631 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,580,592 - 1,600,307 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,928,574 - 6,948,303 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,885,636 - 5,905,351 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,738,211 - 10,758,403 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,738,222 - 10,757,954 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,729,983 - 9,750,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,356,596 - 7,375,693 (-)NCBICelera
Cytogenetic Map9q11NCBI
Uhrf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554954,153,898 - 4,154,611 (-)NCBIChiLan1.0ChiLan1.0
UHRF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2209,302,493 - 9,355,349 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,531,805 - 8,584,592 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,926,583 - 3,979,163 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,872,753 - 4,925,330 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,872,753 - 4,925,330 (+)Ensemblpanpan1.1panPan2
UHRF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12054,858,673 - 54,889,769 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2054,859,947 - 54,889,907 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2054,583,125 - 54,615,199 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,513,260 - 55,545,335 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,513,262 - 55,545,339 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12054,574,546 - 54,606,612 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,055,222 - 55,087,332 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,253,102 - 55,285,205 (-)NCBIUU_Cfam_GSD_1.0
Uhrf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118214,944,645 - 214,972,502 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,862,367 - 2,888,946 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,863,651 - 2,890,116 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UHRF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl273,898,071 - 73,931,769 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1273,898,061 - 73,937,727 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2274,678,503 - 74,712,233 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UHRF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,592,362 - 4,642,179 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl64,592,919 - 4,642,445 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660813,489,316 - 3,544,391 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uhrf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248284,898,677 - 4,929,872 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248284,898,786 - 4,929,136 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Uhrf1
477 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1666
Count of miRNA genes:502
Interacting mature miRNAs:597
Transcripts:ENSMUST00000001258, ENSMUST00000113035, ENSMUST00000113038, ENSMUST00000113039, ENSMUST00000137876, ENSMUST00000139654, ENSMUST00000142387
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174371089167806995Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
14700692Cihvtq1_mcoxsackieviral infection heart viral titre QTL 1 (mouse)175000702870006995Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined175020395784204103Mouse
4142243Lfnq5_mlung function QTL 5 (mouse)Not determined5173897957534623Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175175842585758612Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175175842585758612Mouse

Markers in Region
RH125355  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381756,323,080 - 56,323,253UniSTSGRCm38
MGSCv371756,462,503 - 56,462,676UniSTSGRCm37
Cytogenetic Map17D-E1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001111079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001111080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001413357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001413358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001413359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001413360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB066245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC026385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC073761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF274046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY140812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D87908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000001258   ⟹   ENSMUSP00000001258
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1756,610,321 - 56,630,486 (+)Ensembl
GRCm38.p6 Ensembl1756,303,321 - 56,323,486 (+)Ensembl
RefSeq Acc Id: ENSMUST00000113035   ⟹   ENSMUSP00000108658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1756,611,313 - 56,630,486 (+)Ensembl
GRCm38.p6 Ensembl1756,304,313 - 56,323,486 (+)Ensembl
RefSeq Acc Id: ENSMUST00000113038   ⟹   ENSMUSP00000108661
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1756,610,400 - 56,630,486 (+)Ensembl
GRCm38.p6 Ensembl1756,303,400 - 56,323,486 (+)Ensembl
RefSeq Acc Id: ENSMUST00000113039   ⟹   ENSMUSP00000108662
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1756,611,348 - 56,630,486 (+)Ensembl
GRCm38.p6 Ensembl1756,304,348 - 56,323,486 (+)Ensembl
RefSeq Acc Id: ENSMUST00000137876
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1756,619,663 - 56,620,176 (+)Ensembl
GRCm38.p6 Ensembl1756,312,663 - 56,313,176 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139654
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1756,625,026 - 56,629,339 (+)Ensembl
GRCm38.p6 Ensembl1756,318,026 - 56,322,339 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142387   ⟹   ENSMUSP00000125830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1756,611,407 - 56,617,719 (+)Ensembl
GRCm38.p6 Ensembl1756,304,407 - 56,310,719 (+)Ensembl
RefSeq Acc Id: NM_001111078   ⟹   NP_001104548
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,611,346 - 56,630,486 (+)NCBI
GRCm381756,304,313 - 56,323,486 (+)NCBI
MGSCv371756,442,760 - 56,462,909 (+)RGD
Celera1760,657,174 - 60,672,221 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001111079   ⟹   NP_001104549
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,610,405 - 56,630,486 (+)NCBI
GRCm381756,303,337 - 56,323,486 (+)ENTREZGENE
MGSCv371756,442,760 - 56,462,909 (+)RGD
Celera1760,657,174 - 60,672,221 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001111080   ⟹   NP_001104550
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,611,346 - 56,630,486 (+)NCBI
GRCm381756,304,313 - 56,323,486 (+)NCBI
MGSCv371756,442,760 - 56,462,909 (+)RGD
Celera1760,657,174 - 60,672,221 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001413357   ⟹   NP_001400286
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,610,405 - 56,630,486 (+)NCBI
RefSeq Acc Id: NM_001413358   ⟹   NP_001400287
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,610,405 - 56,630,486 (+)NCBI
RefSeq Acc Id: NM_001413359   ⟹   NP_001400288
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,610,405 - 56,630,486 (+)NCBI
RefSeq Acc Id: NM_001413360   ⟹   NP_001400289
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,611,346 - 56,630,486 (+)NCBI
RefSeq Acc Id: NM_010931   ⟹   NP_035061
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391756,610,405 - 56,630,486 (+)NCBI
GRCm381756,303,337 - 56,323,486 (+)ENTREZGENE
MGSCv371756,442,760 - 56,462,909 (+)RGD
Celera1760,657,174 - 60,672,221 (+)RGD
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001104548 (Get FASTA)   NCBI Sequence Viewer  
  NP_001104549 (Get FASTA)   NCBI Sequence Viewer  
  NP_001104550 (Get FASTA)   NCBI Sequence Viewer  
  NP_001400286 (Get FASTA)   NCBI Sequence Viewer  
  NP_001400287 (Get FASTA)   NCBI Sequence Viewer  
  NP_001400288 (Get FASTA)   NCBI Sequence Viewer  
  NP_001400289 (Get FASTA)   NCBI Sequence Viewer  
  NP_035061 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH22167 (Get FASTA)   NCBI Sequence Viewer  
  AAK55743 (Get FASTA)   NCBI Sequence Viewer  
  BAA74579 (Get FASTA)   NCBI Sequence Viewer  
  BAB79496 (Get FASTA)   NCBI Sequence Viewer  
  BAC35985 (Get FASTA)   NCBI Sequence Viewer  
  BAE25499 (Get FASTA)   NCBI Sequence Viewer  
  BAE26398 (Get FASTA)   NCBI Sequence Viewer  
  BAE26496 (Get FASTA)   NCBI Sequence Viewer  
  BAE27560 (Get FASTA)   NCBI Sequence Viewer  
  BAE27632 (Get FASTA)   NCBI Sequence Viewer  
  BAE29605 (Get FASTA)   NCBI Sequence Viewer  
  BAE30624 (Get FASTA)   NCBI Sequence Viewer  
  BAE30730 (Get FASTA)   NCBI Sequence Viewer  
  BAE31605 (Get FASTA)   NCBI Sequence Viewer  
  BAE31708 (Get FASTA)   NCBI Sequence Viewer  
  EDL38161 (Get FASTA)   NCBI Sequence Viewer  
  EDL38162 (Get FASTA)   NCBI Sequence Viewer  
  EDL38163 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000001258
  ENSMUSP00000001258.9
  ENSMUSP00000108658
  ENSMUSP00000108658.2
  ENSMUSP00000108661
  ENSMUSP00000108661.2
  ENSMUSP00000108662
  ENSMUSP00000108662.3
  ENSMUSP00000125830.2
GenBank Protein Q8VDF2 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_035061   ⟸   NM_010931
- Peptide Label: isoform A
- UniProtKB: Q8VIA1 (UniProtKB/Swiss-Prot),   Q8C6F1 (UniProtKB/Swiss-Prot),   Q3ULQ0 (UniProtKB/Swiss-Prot),   Q3ULF2 (UniProtKB/Swiss-Prot),   Q3UIE6 (UniProtKB/Swiss-Prot),   Q3UI74 (UniProtKB/Swiss-Prot),   Q3U9P2 (UniProtKB/Swiss-Prot),   Q3U9D7 (UniProtKB/Swiss-Prot),   Q9Z1H6 (UniProtKB/Swiss-Prot),   Q8VDF2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001104549   ⟸   NM_001111079
- Peptide Label: isoform B
- UniProtKB: Q8VDF2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001104548   ⟸   NM_001111078
- Peptide Label: isoform A
- UniProtKB: Q8VIA1 (UniProtKB/Swiss-Prot),   Q8C6F1 (UniProtKB/Swiss-Prot),   Q3ULQ0 (UniProtKB/Swiss-Prot),   Q3ULF2 (UniProtKB/Swiss-Prot),   Q3UIE6 (UniProtKB/Swiss-Prot),   Q3UI74 (UniProtKB/Swiss-Prot),   Q3U9P2 (UniProtKB/Swiss-Prot),   Q3U9D7 (UniProtKB/Swiss-Prot),   Q9Z1H6 (UniProtKB/Swiss-Prot),   Q8VDF2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001104550   ⟸   NM_001111080
- Peptide Label: isoform B
- UniProtKB: Q8VDF2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000001258   ⟸   ENSMUST00000001258
RefSeq Acc Id: ENSMUSP00000108658   ⟸   ENSMUST00000113035
RefSeq Acc Id: ENSMUSP00000108661   ⟸   ENSMUST00000113038
RefSeq Acc Id: ENSMUSP00000108662   ⟸   ENSMUST00000113039
RefSeq Acc Id: ENSMUSP00000125830   ⟸   ENSMUST00000142387
RefSeq Acc Id: NP_001400286   ⟸   NM_001413357
- Peptide Label: isoform C
RefSeq Acc Id: NP_001400287   ⟸   NM_001413358
- Peptide Label: isoform D
RefSeq Acc Id: NP_001400288   ⟸   NM_001413359
- Peptide Label: isoform E
RefSeq Acc Id: NP_001400289   ⟸   NM_001413360
- Peptide Label: isoform D
Protein Domains
Ubiquitin-like   YDG

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VDF2-F1-model_v2 AlphaFold Q8VDF2 1-782 view protein structure

Promoters
RGD ID:13676508
Promoter ID:EPDNEW_M22403
Type:initiation region
Name:Uhrf1_1
Description:Mus musculus ubiquitin-like, containing PHD and RING finger domains,1 , transcript variant 4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22404  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381756,303,406 - 56,303,466EPDNEW
RGD ID:13676510
Promoter ID:EPDNEW_M22404
Type:multiple initiation site
Name:Uhrf1_2
Description:Mus musculus ubiquitin-like, containing PHD and RING finger domains,1 , transcript variant 4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22403  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381756,304,348 - 56,304,408EPDNEW
RGD ID:6828862
Promoter ID:MM_KWN:23879
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:NM_001111079,   OTTMUST00000049736
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361756,442,339 - 56,442,839 (+)MPROMDB
RGD ID:6828860
Promoter ID:MM_KWN:23880
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   Spleen
Transcripts:NM_001111078,   NM_001111080,   OTTMUST00000049740
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361756,443,016 - 56,443,832 (+)MPROMDB
RGD ID:6828863
Promoter ID:MM_KWN:23881
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000049741
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361756,451,466 - 56,451,966 (+)MPROMDB
RGD ID:6828864
Promoter ID:MM_KWN:23882
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000049742
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361756,456,766 - 56,457,266 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1338889 AgrOrtholog
Ensembl Genes ENSMUSG00000001228 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000001258 ENTREZGENE
  ENSMUST00000001258.15 UniProtKB/Swiss-Prot
  ENSMUST00000113035 ENTREZGENE
  ENSMUST00000113035.8 UniProtKB/Swiss-Prot
  ENSMUST00000113038 ENTREZGENE
  ENSMUST00000113038.8 UniProtKB/Swiss-Prot
  ENSMUST00000113039 ENTREZGENE
  ENSMUST00000113039.9 UniProtKB/Swiss-Prot
  ENSMUST00000142387.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.280.10 UniProtKB/Swiss-Prot
  2.30.30.1150 UniProtKB/Swiss-Prot
  2.30.30.140 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
InterPro PUA-like_sf UniProtKB/Swiss-Prot
  SRA-YDG_sf UniProtKB/Swiss-Prot
  SRA_YDG UniProtKB/Swiss-Prot
  TTD_dom UniProtKB/Swiss-Prot
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/Swiss-Prot
  Ubiquitin_subgr UniProtKB/TrEMBL
  Ubl_UHRF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UHRF1/2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot
  Znf_PHD UniProtKB/Swiss-Prot
  Znf_PHD-finger UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
KEGG Report mmu:18140 UniProtKB/Swiss-Prot
MGD MGI:1338889 ENTREZGENE
NCBI Gene 18140 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE UHRF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14140 UniProtKB/Swiss-Prot
Pfam PHD UniProtKB/Swiss-Prot
  SAD_SRA UniProtKB/Swiss-Prot
  TTD UniProtKB/Swiss-Prot
  ubiquitin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Uhrf1 PhenoGen
PRINTS UBIQUITIN UniProtKB/TrEMBL
PROSITE UBIQUITIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  YDG UniProtKB/Swiss-Prot
  ZF_PHD_1 UniProtKB/Swiss-Prot
  ZF_PHD_2 UniProtKB/Swiss-Prot
  ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
SMART PHD UniProtKB/Swiss-Prot
  RING UniProtKB/Swiss-Prot
  SRA UniProtKB/Swiss-Prot
  UBQ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/Swiss-Prot
  SSF88697 UniProtKB/Swiss-Prot
UniProt E9Q5Y5_MOUSE UniProtKB/TrEMBL
  Q3U9D7 ENTREZGENE
  Q3U9P2 ENTREZGENE
  Q3UI74 ENTREZGENE
  Q3UIE6 ENTREZGENE
  Q3ULF2 ENTREZGENE
  Q3ULQ0 ENTREZGENE
  Q8C6F1 ENTREZGENE
  Q8VDF2 ENTREZGENE
  Q8VIA1 ENTREZGENE
  Q9Z1H6 ENTREZGENE
  UHRF1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3U9D7 UniProtKB/Swiss-Prot
  Q3U9P2 UniProtKB/Swiss-Prot
  Q3UI74 UniProtKB/Swiss-Prot
  Q3UIE6 UniProtKB/Swiss-Prot
  Q3ULF2 UniProtKB/Swiss-Prot
  Q3ULQ0 UniProtKB/Swiss-Prot
  Q8C6F1 UniProtKB/Swiss-Prot
  Q8VIA1 UniProtKB/Swiss-Prot
  Q9Z1H6 UniProtKB/Swiss-Prot