Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MAT2B mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of MAT2B mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of MAT2B mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MAT2B mRNA | CTD | PMID:18343893 and PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mat2b (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MAT2B mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MAT2B mRNA | CTD | PMID:15328365 and PMID:23994337 | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:18343893 | 2-methylcholine | affects expression | ISO | MAT2B (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of MAT2B mRNA | CTD | PMID:21179406 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23994337 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of MAT2B protein | CTD | PMID:31675489 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of MAT2B mRNA | CTD | PMID:18648102 | acrolein | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of MAT2B mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of MAT2B mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | MAT2B (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of MAT2B gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of MAT2B mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of MAT2B mRNA | CTD | PMID:32699268 | arsane | affects expression | ISO | MAT2B (Homo sapiens) | 6480464 | Arsenic affects the expression of MAT2B mRNA | CTD | PMID:18487201 | arsenic atom | affects expression | ISO | MAT2B (Homo sapiens) | 6480464 | Arsenic affects the expression of MAT2B mRNA | CTD | PMID:18487201 | arsenous acid | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MAT2B protein] | CTD | PMID:26598702 | benzatropine | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in increased expression of MAT2B protein | CTD | PMID:34122009 | beta-naphthoflavone | increases expression | EXP | | 6480464 | beta-Naphthoflavone results in increased expression of MAT2B mRNA | CTD | PMID:23994337 | bisphenol A | increases expression | ISO | Mat2b (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of MAT2B mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of MAT2B protein | CTD | PMID:37567409 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MAT2B mRNA | CTD | PMID:33221593 | bisphenol A | increases methylation | ISO | Mat2b (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of MAT2B gene | CTD | PMID:28505145 | butanal | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of MAT2B mRNA | CTD | PMID:26079696 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MAT2B gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of MAT2B mRNA | CTD | PMID:37019170 | cisplatin | increases expression | ISO | MAT2B (Homo sapiens) | 6480464 | Cisplatin results in increased expression of MAT2B mRNA | CTD | PMID:27392435 | clozapine | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | Clozapine results in decreased expression of MAT2B protein | CTD | PMID:34122009 | copper(II) sulfate | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of MAT2B mRNA | CTD | PMID:19549813 | Cuprizon | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in increased expression of MAT2B protein | CTD | PMID:34122009 | decabromodiphenyl ether | increases expression | ISO | MAT2B (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of MAT2B protein | CTD | PMID:31675489 | diarsenic trioxide | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MAT2B protein] | CTD | PMID:26598702 | dicrotophos | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of MAT2B mRNA | CTD | PMID:28302478 | diethylstilbestrol | increases expression | ISO | MAT2B (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of MAT2B mRNA | CTD | PMID:36621641 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of MAT2B mRNA | CTD | PMID:30319688 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of MAT2B mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of MAT2B mRNA] | CTD | PMID:22206623 | furan | decreases methylation | ISO | Mat2b (Rattus norvegicus) | 6480464 | furan results in decreased methylation of MAT2B gene | CTD | PMID:22079235 | isobutanol | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of MAT2B mRNA | CTD | PMID:29432896 | ivermectin | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of MAT2B protein | CTD | PMID:32959892 | lead(0) | affects expression | ISO | MAT2B (Homo sapiens) | 6480464 | Lead affects the expression of MAT2B mRNA | CTD | PMID:28903495 | NADP zwitterion | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [resveratrol co-treated with NADP] binds to MAT2B protein and NADP binds to and results in increased activity of MAT2B protein | CTD | PMID:25526675 | NADP(+) | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [resveratrol co-treated with NADP] binds to MAT2B protein and NADP binds to and results in increased activity of MAT2B protein | CTD | PMID:25526675 | nickel atom | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | Nickel results in decreased expression of MAT2B mRNA | CTD | PMID:23195993 | ozone | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of MAT2B mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | p-toluidine | increases expression | ISO | Mat2b (Rattus norvegicus) | 6480464 | 4-toluidine results in increased expression of MAT2B mRNA | CTD | PMID:27638505 | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of MAT2B protein | CTD | PMID:26178269 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MAT2B mRNA | CTD | PMID:36331819 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of MAT2B mRNA | CTD | PMID:23811191 | potassium dichromate | increases expression | EXP | | 6480464 | Potassium Dichromate results in increased expression of MAT2B mRNA | CTD | PMID:23608068 | Propiverine | affects binding | ISO | Mat2b (Rattus norvegicus) | 6480464 | propiverine binds to MAT2B protein | CTD | PMID:29273565 | resveratrol | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [resveratrol co-treated with NADP] binds to MAT2B protein more ... | CTD | PMID:23814050 and PMID:25526675 | resveratrol | increases expression | ISO | MAT2B (Homo sapiens) | 6480464 | resveratrol results in increased expression of MAT2B mRNA | CTD | PMID:23814050 | SB 431542 | multiple interactions | ISO | MAT2B (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of MAT2B protein | CTD | PMID:37664457 | sevoflurane | increases expression | EXP | | 6480464 | Sevoflurane results in increased expression of MAT2B protein | CTD | PMID:35249202 | trichloroethene | increases methylation | ISO | Mat2b (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of MAT2B gene | CTD | PMID:27618143 | uranium atom | affects expression | ISO | MAT2B (Homo sapiens) | 6480464 | Uranium affects the expression of MAT2B mRNA | CTD | PMID:15672453 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of MAT2B mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | MAT2B (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MAT2B mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | MAT2B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MAT2B mRNA | CTD | PMID:25979313 | zearalenone | decreases expression | EXP | | 6480464 | Zearalenone results in decreased expression of MAT2B protein | CTD | PMID:36252740 | |