Mat2b (methionine adenosyltransferase 2 non-catalytic beta subunit methionine) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mat2b (methionine adenosyltransferase 2 non-catalytic beta subunit methionine) Mus musculus
Analyze
Symbol: Mat2b
Name: methionine adenosyltransferase 2 non-catalytic beta subunit methionine
RGD ID: 1618238
MGI Page MGI
Description: Predicted to enable enzyme binding activity and methionine adenosyltransferase regulator activity. Predicted to be involved in S-adenosylmethionine biosynthetic process. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; genitourinary system; respiratory system; and sensory organ. Orthologous to human MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110064C04Rik; 2410018D16Rik; AI182287; AU022853; MAT II beta; MAT-II; MATII; MATIIbeta; methionine adenosyltransferase 2 beta subunit; methionine adenosyltransferase 2 subunit beta; methionine adenosyltransferase II beta; methionine adenosyltransferase II, beta; RP23-382C18.2; TGR
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,570,141 - 40,586,030 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1140,570,141 - 40,586,030 (-)EnsemblGRCm39 Ensembl
GRCm381140,679,314 - 40,695,203 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,679,314 - 40,695,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371140,492,816 - 40,506,115 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361140,522,737 - 40,536,036 (-)NCBIMGSCv36mm8
Celera1144,529,462 - 44,542,765 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. S-adenosylmethionine in liver health, injury, and cancer. Lu SC and Mato JM, Physiol Rev. 2012 Oct;92(4):1515-42. doi: 10.1152/physrev.00047.2011.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10644686   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12904583  
PMID:14610273   PMID:14681479   PMID:16141072   PMID:16141073   PMID:16512683   PMID:17967808   PMID:18614015   PMID:18799693   PMID:21267068   PMID:21873635   PMID:27113764   PMID:29021282  
PMID:29695199   PMID:30265288   PMID:30333137   PMID:30753104   PMID:31748650   PMID:32046373   PMID:32325033   PMID:34702858  


Genomics

Comparative Map Data
Mat2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,570,141 - 40,586,030 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1140,570,141 - 40,586,030 (-)EnsemblGRCm39 Ensembl
GRCm381140,679,314 - 40,695,203 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,679,314 - 40,695,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371140,492,816 - 40,506,115 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361140,522,737 - 40,536,036 (-)NCBIMGSCv36mm8
Celera1144,529,462 - 44,542,765 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.4NCBI
MAT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385163,503,064 - 163,519,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5163,503,114 - 163,519,558 (+)EnsemblGRCh38hg38GRCh38
GRCh375162,930,070 - 162,946,360 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,862,809 - 162,878,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera5158,964,332 - 158,980,423 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5158,029,749 - 158,046,037 (+)NCBIHuRef
CHM1_15162,362,532 - 162,378,812 (+)NCBICHM1_1
T2T-CHM13v2.05164,038,230 - 164,054,512 (+)NCBIT2T-CHM13v2.0
Mat2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,609,202 - 25,626,694 (-)NCBIGRCr8
mRatBN7.21025,106,928 - 25,122,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,106,930 - 25,122,777 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1029,861,993 - 29,877,026 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,350,532 - 29,365,565 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,837,185 - 24,852,218 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,832,096 - 25,848,045 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,832,072 - 25,847,994 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01025,686,294 - 25,701,795 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,713,132 - 25,718,879 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1024,666,794 - 24,680,351 (-)NCBICelera
Cytogenetic Map10q12NCBI
Mat2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540816,910,414 - 16,924,663 (+)NCBIChiLan1.0ChiLan1.0
MAT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24158,675,643 - 158,692,011 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15156,815,297 - 156,831,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05158,879,425 - 158,895,690 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15165,656,086 - 165,672,176 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5165,656,086 - 165,672,176 (+)Ensemblpanpan1.1panPan2
MAT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,703,991 - 47,726,363 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,709,576 - 47,726,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha447,597,100 - 47,621,728 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0448,134,581 - 48,159,235 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl448,137,166 - 48,156,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1447,918,036 - 47,942,655 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0448,076,525 - 48,101,129 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0448,596,150 - 48,620,797 (-)NCBIUU_Cfam_GSD_1.0
Mat2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213102,094,901 - 102,111,644 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936515544,037 - 561,182 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936515544,218 - 561,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1660,255,358 - 60,274,135 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11660,255,541 - 60,274,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21665,065,436 - 65,111,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103244929
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12365,776,808 - 65,792,871 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2365,779,437 - 65,792,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666097990,267 - 1,006,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mat2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473326,297,653 - 26,306,942 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473326,296,920 - 26,309,228 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mat2b
472 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1149
Count of miRNA genes:567
Interacting mature miRNAs:676
Transcripts:ENSMUST00000040167, ENSMUST00000101347, ENSMUST00000109307, ENSMUST00000135617, ENSMUST00000137797, ENSMUST00000141830, ENSMUST00000156867
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
10043922Alcw9_malcohol withdrawal 9 (mouse)Not determined113557861644065931Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
1301814Bbaa7_mB.burgdorferi-associated arthritis 7 (mouse)Not determined112601178044264695Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
1301718Pbw3_mpentobarbital withdrawal QTL 3 (mouse)Not determined113557861644065931Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
1558769Zolw1_mzolpidem withdrawal 1 (mouse)Not determined113557861644065931Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
AU022853  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381140,679,337 - 40,679,541UniSTSGRCm38
MGSCv371140,492,839 - 40,493,043UniSTSGRCm37
Celera1144,529,485 - 44,529,689UniSTS
Cytogenetic Map11A5UniSTS
Whitehead/MRC_RH11545.59UniSTS
AI182287  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381140,679,458 - 40,679,620UniSTSGRCm38
MGSCv371140,492,960 - 40,493,122UniSTSGRCm37
Celera1144,529,606 - 44,529,768UniSTS
Cytogenetic Map11A5UniSTS
Whitehead/MRC_RH11546.73UniSTS


Sequence


Ensembl Acc Id: ENSMUST00000040167   ⟹   ENSMUSP00000048222
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1140,570,141 - 40,583,601 (-)Ensembl
GRCm38.p6 Ensembl1140,679,314 - 40,692,774 (-)Ensembl
Ensembl Acc Id: ENSMUST00000101347   ⟹   ENSMUSP00000098901
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1140,570,141 - 40,586,030 (-)Ensembl
GRCm38.p6 Ensembl1140,679,314 - 40,695,203 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109307
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1140,576,313 - 40,583,455 (-)Ensembl
GRCm38.p6 Ensembl1140,685,486 - 40,692,628 (-)Ensembl
Ensembl Acc Id: ENSMUST00000135617
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1140,578,164 - 40,585,814 (-)Ensembl
GRCm38.p6 Ensembl1140,687,337 - 40,694,987 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1140,571,537 - 40,576,054 (-)Ensembl
GRCm38.p6 Ensembl1140,680,710 - 40,685,227 (-)Ensembl
Ensembl Acc Id: ENSMUST00000141830   ⟹   ENSMUSP00000123878
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1140,571,483 - 40,583,448 (-)Ensembl
GRCm38.p6 Ensembl1140,680,656 - 40,692,621 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156867
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1140,575,521 - 40,576,644 (-)Ensembl
GRCm38.p6 Ensembl1140,684,694 - 40,685,817 (-)Ensembl
RefSeq Acc Id: NM_001199274   ⟹   NP_001186203
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391140,570,141 - 40,586,030 (-)NCBI
GRCm381140,679,314 - 40,695,203 (-)ENTREZGENE
Celera1144,529,462 - 44,545,353 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_134017   ⟹   NP_598778
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391140,570,141 - 40,583,509 (-)NCBI
GRCm381140,679,314 - 40,692,682 (-)NCBI
MGSCv371140,492,816 - 40,506,115 (-)RGD
Celera1144,529,462 - 44,545,353 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_598778   ⟸   NM_134017
- Peptide Label: isoform 1
- UniProtKB: Q99LB6 (UniProtKB/Swiss-Prot),   Q8BYT9 (UniProtKB/Swiss-Prot),   Q8BVX6 (UniProtKB/Swiss-Prot),   Q76LX2 (UniProtKB/Swiss-Prot),   Q5NC89 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001186203   ⟸   NM_001199274
- Peptide Label: isoform 2
- UniProtKB: Q99LB6 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000048222   ⟸   ENSMUST00000040167
Ensembl Acc Id: ENSMUSP00000098901   ⟸   ENSMUST00000101347
Ensembl Acc Id: ENSMUSP00000123878   ⟸   ENSMUST00000141830
Protein Domains
RmlD-like substrate binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99LB6-F1-model_v2 AlphaFold Q99LB6 1-334 view protein structure

Promoters
RGD ID:6821235
Promoter ID:MM_KWN:6987
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000040167,   ENSMUST00000109307,   OTTMUST00000012103
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361140,505,671 - 40,506,542 (-)MPROMDB
RGD ID:6821237
Promoter ID:MM_KWN:6988
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000012100,   OTTMUST00000012106
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361140,508,174 - 40,508,674 (-)MPROMDB
RGD ID:8674306
Promoter ID:EPDNEW_M15183
Type:initiation region
Name:Mat2b_1
Description:Mus musculus methionine adenosyltransferase II, beta , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15184  EPDNEW_M15185  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381140,692,658 - 40,692,718EPDNEW
RGD ID:8674308
Promoter ID:EPDNEW_M15184
Type:initiation region
Name:Mat2b_2
Description:Mus musculus methionine adenosyltransferase II, beta , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15183  EPDNEW_M15185  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381140,694,941 - 40,695,001EPDNEW
RGD ID:8674310
Promoter ID:EPDNEW_M15185
Type:single initiation site
Name:Mat2b_3
Description:Mus musculus methionine adenosyltransferase II, beta , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15183  EPDNEW_M15184  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381140,695,218 - 40,695,278EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913667 AgrOrtholog
Ensembl Genes ENSMUSG00000042032 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000040167 ENTREZGENE
  ENSMUST00000040167.11 UniProtKB/Swiss-Prot
  ENSMUST00000101347 ENTREZGENE
  ENSMUST00000101347.10 UniProtKB/Swiss-Prot
  ENSMUST00000141830.8 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro dTDP_dehydrorham_reduct UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RmlD-like-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:108645 UniProtKB/Swiss-Prot
MGD MGI:1913667 ENTREZGENE
NCBI Gene Mat2b ENTREZGENE
PANTHER METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10491 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RmlD_sub_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mat2b PhenoGen
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E0CYU5_MOUSE UniProtKB/TrEMBL
  MAT2B_MOUSE UniProtKB/Swiss-Prot
  Q5NC89 ENTREZGENE
  Q76LX2 ENTREZGENE
  Q8BVX6 ENTREZGENE
  Q8BYT9 ENTREZGENE
  Q99LB6 ENTREZGENE
UniProt Secondary Q5NC89 UniProtKB/Swiss-Prot
  Q76LX2 UniProtKB/Swiss-Prot
  Q8BVX6 UniProtKB/Swiss-Prot
  Q8BYT9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Mat2b  methionine adenosyltransferase 2 non-catalytic beta subunit methionine  2410018D16Rik  RIKEN cDNA 2410018D16 gene  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 2410018D16Rik  RIKEN cDNA 2410018D16 gene  Mat2b  methionine adenosyltransferase 2 non-catalytic beta subunit methionine  Symbol and/or name change 5135510 APPROVED
2023-06-27 Mat2b  methionine adenosyltransferase 2 non-catalytic beta subunit methionine  Mat2b  methionine adenosyltransferase II, beta  Symbol and/or name change 5135510 APPROVED