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Gene: Tgfb3 (transforming growth factor, beta 3) Mus musculus
Symbol: Tgfb3
Name: transforming growth factor, beta 3
Description: Predicted to have several functions, including cytokine activity; transforming growth factor beta binding activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including animal organ development; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and regulation of apoptotic process. Localizes to extracellular matrix. Is expressed in several structures, including alimentary system; embryo mesenchyme; heart and pericardium; respiratory system; and skin. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 5; arrhythmogenic right ventricular cardiomyopathy; and arrhythmogenic right ventricular dysplasia 1. Orthologous to human TGFB3 (transforming growth factor beta 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC118722; TGF-beta-3; Tgfb-3; transforming growth factor beta-3; transforming growth factor beta-3 proprotein
Homo sapiens (human) : TGFB3 (transforming growth factor beta 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfb3 (transforming growth factor, beta 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfb3 (transforming growth factor beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFB3 (transforming growth factor beta 3)
Canis lupus familiaris (dog) : TGFB3 (transforming growth factor beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfb3 (transforming growth factor beta 3)
Sus scrofa (pig) : TGFB3 (transforming growth factor beta 3)
Chlorocebus sabaeus (African green monkey) : TGFB3 (transforming growth factor beta 3)
Heterocephalus glaber (naked mole-rat) : Tgfb3 (transforming growth factor beta 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1286,056,745 - 86,079,041 (-)EnsemblGRCm38mm10GRCm38
GRCm381286,056,743 - 86,079,041 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371287,397,693 - 87,419,991 (-)NCBIGRCm37mm9NCBIm37
MGSCv361286,945,847 - 86,967,637 (-)NCBImm8
Celera1287,516,891 - 87,539,154 (-)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1240.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tgfb3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733158
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.