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Gene: Tgfb3 (transforming growth factor, beta 3) Mus musculus
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Symbol: Tgfb3
Name: transforming growth factor, beta 3
Description: Predicted to have several functions, including cytokine activity; transforming growth factor beta binding activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including animal organ development; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and regulation of apoptotic process. Localizes to extracellular matrix. Is expressed in several structures, including alimentary system; embryo mesenchyme; heart and pericardium; respiratory system; and skin. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 5; arrhythmogenic right ventricular cardiomyopathy; and arrhythmogenic right ventricular dysplasia 1. Orthologous to human TGFB3 (transforming growth factor beta 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC118722; TGF-beta-3; Tgfb-3; transforming growth factor beta-3; transforming growth factor beta-3 proprotein
Orthologs:
Homo sapiens (human) : TGFB3 (transforming growth factor beta 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfb3 (transforming growth factor, beta 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfb3 (transforming growth factor beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFB3 (transforming growth factor beta 3)
Canis lupus familiaris (dog) : TGFB3 (transforming growth factor beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfb3 (transforming growth factor beta 3)
Sus scrofa (pig) : TGFB3 (transforming growth factor beta 3)
Chlorocebus sabaeus (African green monkey) : TGFB3 (transforming growth factor beta 3)
Heterocephalus glaber (naked mole-rat) : Tgfb3 (transforming growth factor beta 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1286,056,745 - 86,079,041 (-)EnsemblGRCm38mm10GRCm38
GRCm381286,056,743 - 86,079,041 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371287,397,693 - 87,419,991 (-)NCBIGRCm37mm9NCBIm37
MGSCv361286,945,847 - 86,967,637 (-)NCBImm8
Celera1287,516,891 - 87,539,154 (-)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1240.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tgfb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733158
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.