Slc1a5 (solute carrier family 1 (neutral amino acid transporter), member 5) - Rat Genome Database

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Gene: Slc1a5 (solute carrier family 1 (neutral amino acid transporter), member 5) Mus musculus
Analyze
Symbol: Slc1a5
Name: solute carrier family 1 (neutral amino acid transporter), member 5
RGD ID: 1550772
MGI Page MGI
Description: Enables L-aspartate transmembrane transporter activity and neutral L-amino acid transmembrane transporter activity. Involved in L-aspartate import across plasma membrane and transport across blood-brain barrier. Located in basal plasma membrane. Is active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and respiratory system. Orthologous to human SLC1A5 (solute carrier family 1 member 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AAAT; ASC; ASC-like Na(+)-dependent neutral amino acid transporter ASCT2; ASCT2; ATB(0); ATBO; insulin-activated amino acid transporter; M7V1; M7VS1; MGC46952; neutral amino acid transporter B(0); R16; RDRC; Slc1a7; sodium-dependent neutral amino acid transporter type 2; solute carrier family 1 member 5; solute carrier family 1, member 7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm19187  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,515,259 - 16,532,199 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,515,265 - 16,532,199 (+)EnsemblGRCm39 Ensembl
GRCm38716,781,334 - 16,798,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,781,340 - 16,798,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,366,695 - 17,383,623 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,939,929 - 15,956,765 (+)NCBIMGSCv36mm8
Celera713,979,416 - 13,996,329 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(S)-colchicine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-bromohexadecanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
adenine  (ISO)
aflatoxin B1  (ISO)
alpha-phellandrene  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
Bardoxolone methyl  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzoates  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcium silicate  (EXP)
cefaloridine  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (EXP)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corosolic acid  (ISO)
coumarin  (ISO)
crocidolite asbestos  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP)
dextran sulfate  (EXP)
Di-n-octyl phthalate  (EXP)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dieldrin  (EXP)
diethyl phthalate  (EXP)
Diisodecyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dioxygen  (ISO)
disodium selenite  (ISO)
dithioerythritol  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
etoposide  (ISO)
folic acid  (EXP)
formaldehyde  (EXP)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (ISO)
hydroxyurea  (ISO)
ifosfamide  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP)
ivermectin  (ISO)
L-methionine  (EXP)
lamivudine  (ISO)
lipopolysaccharide  (EXP,ISO)
Lobetyolin  (ISO)
maneb  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
N(4)-hydroxycytidine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (EXP)
Nonylphenol  (ISO)
ochratoxin A  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (EXP)
pentachlorophenol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (EXP,ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (EXP)
thiazoles  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
tolcapone  (ISO)
tributylstannane  (EXP)
trichloroethene  (ISO)
Triptolide  (EXP)
trovafloxacin  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
XL147  (EXP)
zearalenone  (ISO)
zidovudine  (ISO)
zinc dichloride  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
basal plasma membrane  (IDA)
melanosome  (IEA)
membrane  (ISO,ISS)
plasma membrane  (IBA,IDA,ISO,ISS)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Tissue-based metabolomics reveals metabolic biomarkers and potential therapeutic targets for esophageal squamous cell carcinoma. Chen Z, etal., J Pharm Biomed Anal. 2021 Apr 15;197:113937. doi: 10.1016/j.jpba.2021.113937. Epub 2021 Feb 5.
2. Clinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinoma. Honjo H, etal., J Surg Oncol. 2016 Mar;113(4):381-9. doi: 10.1002/jso.24160. Epub 2016 Mar 3.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. Piao L, etal., J Mol Med (Berl). 2013 Oct;91(10):1185-97. doi: 10.1007/s00109-013-1064-7. Epub 2013 Jun 21.
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer. Toyoda M, etal., Br J Cancer. 2014 May 13;110(10):2506-13. doi: 10.1038/bjc.2014.178. Epub 2014 Apr 24.
9. Clinical significance of coexpression of L-type amino acid transporter 1 (LAT1) and ASC amino acid transporter 2 (ASCT2) in lung adenocarcinoma. Yazawa T, etal., Am J Transl Res. 2015 Jun 15;7(6):1126-39. eCollection 2015.
Additional References at PubMed
PMID:7702599   PMID:8662767   PMID:10349636   PMID:10725249   PMID:10922068   PMID:10933718   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12050356   PMID:12477932   PMID:12505721  
PMID:12584318   PMID:12904583   PMID:14563674   PMID:14622120   PMID:14681479   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18973680   PMID:19012749   PMID:19382234   PMID:21267068  
PMID:21812036   PMID:21873635   PMID:24792914   PMID:27143784   PMID:28553292   PMID:30171039   PMID:30185558   PMID:30801233   PMID:32518258   PMID:32554809   PMID:34301346   PMID:34647520  
PMID:35237783   PMID:36114006   PMID:36462557   PMID:36654781   PMID:37578594   PMID:38058065   PMID:38159852   PMID:38844111   PMID:39147774   PMID:39255693  


Genomics

Comparative Map Data
Slc1a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,515,259 - 16,532,199 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,515,265 - 16,532,199 (+)EnsemblGRCm39 Ensembl
GRCm38716,781,334 - 16,798,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,781,340 - 16,798,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,366,695 - 17,383,623 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,939,929 - 15,956,765 (+)NCBIMGSCv36mm8
Celera713,979,416 - 13,996,329 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
SLC1A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,774,883 - 46,788,594 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,774,883 - 46,788,594 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,278,140 - 47,291,851 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,969,980 - 51,983,653 (-)NCBINCBI36Build 36hg18NCBI36
Build 341951,969,981 - 51,983,653NCBI
Celera1944,082,395 - 44,096,097 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,702,915 - 43,716,958 (-)NCBIHuRef
CHM1_11947,280,017 - 47,293,715 (-)NCBICHM1_1
T2T-CHM13v2.01949,600,712 - 49,614,415 (-)NCBIT2T-CHM13v2.0
Slc1a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,584,949 - 86,599,052 (+)NCBIGRCr8
mRatBN7.2177,456,849 - 77,470,952 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,456,694 - 77,470,952 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,837,237 - 82,851,346 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,401,281 - 91,415,390 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,592,328 - 84,606,437 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,710,686 - 78,724,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,710,539 - 78,724,794 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,957,648 - 79,971,751 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,111,082 - 77,125,166 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,189,192 - 77,203,276 (+)NCBI
Celera171,941,916 - 71,956,019 (+)NCBICelera
Cytogenetic Map1q21NCBI
Slc1a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955574798,004 - 806,631 (-)NCBIChiLan1.0ChiLan1.0
SLC1A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,922,399 - 52,939,392 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,793,572 - 54,807,596 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,765,001 - 43,778,981 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,294,052 - 52,308,159 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,294,655 - 52,307,529 (-)Ensemblpanpan1.1panPan2
SLC1A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,150,205 - 109,161,375 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,150,205 - 109,161,141 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,630,028 - 108,640,938 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,676,678 - 109,687,827 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,676,206 - 109,688,731 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,353,817 - 109,364,724 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01108,988,004 - 108,998,931 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,856,686 - 109,867,593 (+)NCBIUU_Cfam_GSD_1.0
Slc1a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,980,757 - 18,992,747 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936664598,468 - 610,698 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936664599,012 - 610,689 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC1A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,647,438 - 52,661,459 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,647,432 - 52,661,464 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2648,026,660 - 48,032,162 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC1A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,139,417 - 40,150,312 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607319,833,875 - 19,850,399 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc1a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,831,368 - 6,838,593 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,830,799 - 6,839,118 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1335
Count of miRNA genes:680
Interacting mature miRNAs:821
Transcripts:ENSMUST00000108496, ENSMUST00000127401, ENSMUST00000131664, ENSMUST00000134407, ENSMUST00000135817, ENSMUST00000141349, ENSMUST00000147814
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
25394569Skmw57_mskeletal muscle weight 57, gastroc (mouse)7458046916687861Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
1302115Abhr3_mallergen-induced bronchial hyperresponsiveness 3 (mouse)Not determined7331599616637423Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse

Markers in Region
BB222471  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38716,790,315 - 16,790,462UniSTSGRCm38
MGSCv37717,375,664 - 17,375,811UniSTSGRCm37
Celera713,988,366 - 13,988,513UniSTS
Cytogenetic Map7A2UniSTS
Whitehead/MRC_RH7203.98UniSTS
UniSTS:235608  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38716,797,829 - 16,798,263UniSTSGRCm38
MGSCv37717,383,178 - 17,383,612UniSTSGRCm37
Celera713,995,884 - 13,996,318UniSTS
Cytogenetic Map7A2UniSTS
Slc1a5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A2UniSTS
cM Map79.15UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_391052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC148981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF080267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF246130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D85044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L42115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000108496   ⟹   ENSMUSP00000104136
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,515,265 - 16,532,199 (+)Ensembl
GRCm38.p6 Ensembl716,781,340 - 16,798,274 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127401
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,515,293 - 16,532,199 (+)Ensembl
GRCm38.p6 Ensembl716,781,368 - 16,798,274 (+)Ensembl
Ensembl Acc Id: ENSMUST00000131664
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,519,591 - 16,521,093 (+)Ensembl
GRCm38.p6 Ensembl716,785,666 - 16,787,168 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134407
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,526,952 - 16,530,084 (+)Ensembl
GRCm38.p6 Ensembl716,793,027 - 16,796,159 (+)Ensembl
Ensembl Acc Id: ENSMUST00000135817
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,518,663 - 16,527,631 (+)Ensembl
GRCm38.p6 Ensembl716,784,738 - 16,793,706 (+)Ensembl
Ensembl Acc Id: ENSMUST00000141349
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,527,102 - 16,529,868 (+)Ensembl
GRCm38.p6 Ensembl716,793,177 - 16,795,943 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147814
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,520,296 - 16,527,721 (+)Ensembl
GRCm38.p6 Ensembl716,786,371 - 16,793,796 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206444
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl716,516,323 - 16,521,104 (+)Ensembl
GRCm38.p6 Ensembl716,782,398 - 16,787,179 (+)Ensembl
RefSeq Acc Id: NM_009201   ⟹   NP_033227
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39716,515,271 - 16,532,199 (+)NCBI
GRCm38716,781,346 - 16,798,274 (+)NCBI
MGSCv37717,366,695 - 17,383,623 (+)RGD
Celera713,979,416 - 13,996,329 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539695   ⟹   XP_006539758
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39716,515,259 - 16,532,168 (+)NCBI
GRCm38716,781,345 - 16,798,243 (+)NCBI
Sequence:
RefSeq Acc Id: XR_391052
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39716,515,259 - 16,532,177 (+)NCBI
GRCm38716,781,334 - 16,798,243 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033227   ⟸   NM_009201
- UniProtKB: Q3UFR4 (UniProtKB/TrEMBL),   Q9ESU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006539758   ⟸   XM_006539695
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000104136   ⟸   ENSMUST00000108496

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P51912-F1-model_v2 AlphaFold P51912 1-553 view protein structure

Promoters
RGD ID:6891938
Promoter ID:EPDNEW_M9420
Type:multiple initiation site
Name:Slc1a5_1
Description:Mus musculus solute carrier family 1 , member 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38716,781,369 - 16,781,429EPDNEW
RGD ID:6842040
Promoter ID:MM_KWN:48922
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000065232,   NM_009201,   OTTMUST00000052917
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36717,365,706 - 17,367,737 (+)MPROMDB
RGD ID:6842041
Promoter ID:MM_KWN:48923
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Lung
Transcripts:OTTMUST00000052918
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36717,369,126 - 17,370,102 (+)MPROMDB
RGD ID:6842039
Promoter ID:MM_KWN:48924
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   ES_Cell
Transcripts:OTTMUST00000052919
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36717,370,021 - 17,371,062 (+)MPROMDB
RGD ID:6842045
Promoter ID:MM_KWN:48925
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Lung
Transcripts:OTTMUST00000052920
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36717,370,831 - 17,372,117 (+)MPROMDB
RGD ID:6842043
Promoter ID:MM_KWN:48926
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   Kidney,   Lung
Transcripts:OTTMUST00000052921,   OTTMUST00000052922
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36717,377,441 - 17,379,222 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105305 AgrOrtholog
Ensembl Genes ENSMUSG00000001918 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000108496 ENTREZGENE
  ENSMUST00000108496.9 UniProtKB/TrEMBL
Gene3D-CATH 1.10.3860.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DAACS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na-dicarboxylate_symporter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na-dicarboxylate_symporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na:dicarbo_symporter_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20514 UniProtKB/TrEMBL
MGD MGI:105305 ENTREZGENE
NCBI Gene 20514 ENTREZGENE
PANTHER NEUTRAL AMINO ACID TRANSPORTER B(0) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SODIUM/DICARBOXYLATE SYMPORTER-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SDF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc1a5 PhenoGen
PRINTS EDTRNSPORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NA_DICARBOXYL_SYMP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA_DICARBOXYL_SYMP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF118215 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AAAT_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UFR4 ENTREZGENE, UniProtKB/TrEMBL
  Q5U647_MOUSE UniProtKB/TrEMBL
  Q9ESU7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q61326 UniProtKB/Swiss-Prot