Nuf2 (NUF2, NDC80 kinetochore complex component) - Rat Genome Database

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Gene: Nuf2 (NUF2, NDC80 kinetochore complex component) Mus musculus
Analyze
Symbol: Nuf2
Name: NUF2, NDC80 kinetochore complex component
RGD ID: 1317447
MGI Page MGI
Description: Predicted to be involved in kinetochore organization; mitotic spindle organization; and nuclear division. Predicted to act upstream of or within attachment of spindle microtubules to kinetochore. Predicted to be located in cytosol; kinetochore; and nucleoplasm. Predicted to be part of Ndc80 complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and pancreatic cancer. Orthologous to human NUF2 (NUF2 component of NDC80 kinetochore complex); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410003C07Rik; AU044112; C85691; Cdca; Cdca1; cell division cycle associated 1; cell division cycle-associated protein 1; kinetochore protein Nuf2; Nuf; NUF2, NDC80 kinetochore complex component, homolog; NUF2R
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,325,503 - 169,359,033 (-)NCBIGRCm39mm39
GRCm39 Ensembl1169,325,503 - 169,359,033 (-)Ensembl
GRCm381169,497,934 - 169,531,464 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,497,934 - 169,531,464 (-)EnsemblGRCm38mm10GRCm38
MGSCv371171,428,065 - 171,461,595 (-)NCBIGRCm37mm9NCBIm37
MGSCv361171,334,986 - 171,368,103 (-)NCBImm8
Celera1171,916,559 - 171,956,575 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-hydroxynon-2-enal  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucosamine  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (EXP)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
beta-D-glucosamine  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
copper(II) sulfate  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
Deguelin  (ISO)
diazinon  (ISO)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
dieldrin  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
folic acid  (EXP,ISO)
furan  (ISO)
heptanal  (ISO)
hexanal  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
lucanthone  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nonanal  (ISO)
ochratoxin A  (ISO)
octanal  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (ISO)
PCB138  (EXP)
pentanal  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
phytoestrogen  (ISO)
pirinixic acid  (EXP)
poly(I:C)  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
rotenone  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (ISO)
vincristine  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Chen X, etal., Int J Clin Exp Pathol. 2019 Apr 1;12(4):1233-1247. eCollection 2019.
2. Hayama S, etal., Cancer Res. 2006 Nov 1;66(21):10339-48. doi: 10.1158/0008-5472.CAN-06-2137.
3. Hu P, etal., Biosci Rep. 2015 Jan 14;35(1). pii: BSR20140124. doi: 10.1042/BSR20140124.
4. Hu P, etal., Int J Clin Exp Pathol. 2015 Mar 1;8(3):2638-48. eCollection 2015.
5. Kaneko N, etal., Biochem Biophys Res Commun. 2009 Dec 25;390(4):1235-40. doi: 10.1016/j.bbrc.2009.10.127. Epub 2009 Oct 28.
6. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
7. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
8. Kobayashi Y, etal., Int J Oncol. 2014 Jan;44(1):69-77. doi: 10.3892/ijo.2013.2177. Epub 2013 Nov 15.
9. MGD data from the GO Consortium
10. Obara W, etal., Cancer Sci. 2017 Jul;108(7):1452-1457. doi: 10.1111/cas.13278. Epub 2017 Jun 23.
11. Ohnuma S, etal., Surgery. 2009 Jan;145(1):57-68. doi: 10.1016/j.surg.2008.08.010. Epub 2008 Oct 8.
12. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. RGD automated import pipeline for gene-chemical interactions
15. Sun J, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2019 May 30;39(5):591-597. doi: 10.12122/j.issn.1673-4254.2019.05.15.
16. Sun ZY, etal., J Cancer. 2020 Mar 4;11(10):2921-2934. doi: 10.7150/jca.41834. eCollection 2020.
17. Thang PM, etal., Int J Oncol. 2016 Oct;49(4):1385-93. doi: 10.3892/ijo.2016.3649. Epub 2016 Aug 5.
18. Tokuzumi A, etal., J Dermatol. 2016 Dec;43(12):1399-1405. doi: 10.1111/1346-8138.13436. Epub 2016 May 30.
19. Wang Y, etal., Int J Cancer. 2019 Aug 1;145(3):662-670. doi: 10.1002/ijc.32134. Epub 2019 Feb 4.
20. Xu W, etal., Int J Mol Med. 2019 Aug;44(2):390-404. doi: 10.3892/ijmm.2019.4239. Epub 2019 Jun 11.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11266451   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16919269   PMID:18287559  
PMID:18799693   PMID:19334288   PMID:21677750   PMID:21873635   PMID:26054848   PMID:26410627   PMID:28535371   PMID:32461611  


Genomics

Comparative Map Data
Nuf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,325,503 - 169,359,033 (-)NCBIGRCm39mm39
GRCm39 Ensembl1169,325,503 - 169,359,033 (-)Ensembl
GRCm381169,497,934 - 169,531,464 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,497,934 - 169,531,464 (-)EnsemblGRCm38mm10GRCm38
MGSCv371171,428,065 - 171,461,595 (-)NCBIGRCm37mm9NCBIm37
MGSCv361171,334,986 - 171,368,103 (-)NCBImm8
Celera1171,916,559 - 171,956,575 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
NUF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1163,266,576 - 163,355,764 (+)EnsemblGRCh38hg38GRCh38
GRCh381163,321,948 - 163,355,764 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371163,291,744 - 163,325,549 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,558,347 - 161,592,177 (+)NCBINCBI36hg18NCBI36
Build 341160,023,382 - 160,057,205NCBI
Celera1136,396,004 - 136,429,820 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1134,537,062 - 134,570,886 (+)NCBIHuRef
CHM1_11164,714,625 - 164,748,448 (+)NCBICHM1_1
Nuf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21381,693,675 - 81,722,765 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1381,693,598 - 81,722,766 (-)Ensembl
Rnor_6.01387,818,456 - 87,847,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1387,818,391 - 87,847,263 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01392,450,022 - 92,478,789 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41385,286,634 - 85,315,366 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11385,300,821 - 85,329,554 (-)NCBI
Celera1381,360,832 - 81,390,131 (-)NCBICelera
Cytogenetic Map13q24NCBI
Nuf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546213,082,047 - 13,142,944 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546213,082,874 - 13,142,709 (-)NCBIChiLan1.0ChiLan1.0
NUF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11142,538,420 - 142,572,364 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1142,538,420 - 142,572,364 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01138,743,251 - 138,777,201 (+)NCBIMhudiblu_PPA_v0panPan3
NUF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13819,574,122 - 19,599,821 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3819,574,125 - 19,599,064 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3819,631,382 - 19,659,692 (-)NCBI
ROS_Cfam_1.03819,658,875 - 19,687,209 (-)NCBI
UMICH_Zoey_3.13819,627,147 - 19,652,037 (-)NCBI
UNSW_CanFamBas_1.03819,985,502 - 20,013,790 (-)NCBI
UU_Cfam_GSD_1.03820,277,530 - 20,302,431 (-)NCBI
Nuf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344103,495,918 - 103,524,586 (-)NCBI
SpeTri2.0NW_00493648121,342,667 - 21,371,311 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl487,162,817 - 87,194,170 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1487,162,873 - 87,194,193 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2494,875,757 - 94,907,078 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12565,462,608 - 65,493,242 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2565,462,603 - 65,493,246 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605567,252,523 - 67,283,969 (-)NCBIVero_WHO_p1.0
Nuf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248261,794,084 - 1,831,009 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AU044112  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381169,498,528 - 169,498,639UniSTSGRCm38
GRCm38X79,917,347 - 79,917,458UniSTSGRCm38
MGSCv371171,428,659 - 171,428,770UniSTSGRCm37
MGSCv37X77,162,686 - 77,162,797UniSTSGRCm37
CeleraX71,215,038 - 71,215,149UniSTS
Cytogenetic Map1H2.3-H3UniSTS
Whitehead/MRC_RH12130.65UniSTS
Nuf2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.3-H3UniSTS
cM Map1 UniSTS
px-65a8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A1UniSTS
Cytogenetic Map8B1.2UniSTS
Cytogenetic Map1H2.3-H3UniSTS
Cytogenetic Map17B3UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map16C3.3UniSTS
Cytogenetic Map3G1UniSTS
RH127219  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381169,498,407 - 169,498,615UniSTSGRCm38
GRCm38X79,917,226 - 79,917,434UniSTSGRCm38
MGSCv371171,428,538 - 171,428,746UniSTSGRCm37
MGSCv37X77,162,565 - 77,162,773UniSTSGRCm37
CeleraX71,214,917 - 71,215,125UniSTS
Cytogenetic Map1H2.3-H3UniSTS
Whitehead/MRC_RH12130.54UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135919071169919261Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1136002150170002264Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136334204170334348Mouse
1300837Vmbic1_mventral midbrain iron content 1 (mouse)Not determined1139624618173624738Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139624618173624738Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139774467173774646Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139774467173774646Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139774467173774646Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139774467173774646Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139774467173774646Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139774467173774646Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139774467173774646Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139774467173774646Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147249520171804689Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse
13452397Leusq4_mleucocytosis susceptibility QTL 4 (mouse)1156774467170976071Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1163149528186261999Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164315658190802075Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1166092111195471971Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167730317195471971Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167730317195471971Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167730317195471971Mouse
12792983Liq1_mlimb inflammation QTL 1 (mouse)1167758517191493284Mouse
1301333Mop3_mmorphine preference 3 (mouse)Not determined1167929168189571420Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1168222387195471971Mouse
1301130Sle1a_msystematic lupus erythematosus susceptibility 1a (mouse)Not determined1168358674170239759Mouse
1302037Nktcn1_mnatural killer T cell numbers 1 (mouse)Not determined1168358674171804689Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168481626195471971Mouse
4142065Bmd5b_mbone mineral density 5b (mouse)Not determined169007542171938066Mouse
10412205Bbaa30_mB.burgdorferi-associated arthritis 30 (mouse)Not determined1169211172174628870Mouse
1357854Sle16_msystematic lupus erythematosus susceptibility 16 (mouse)Not determined1169211172177550021Mouse
13207571Tcq11_mtotal cholesterol QTL 11 (mouse)1169310000179820000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:366
Count of miRNA genes:195
Interacting mature miRNAs:213
Transcripts:ENSMUST00000028000, ENSMUST00000111368
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000028000   ⟹   ENSMUSP00000028000
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,325,880 - 169,358,997 (-)Ensembl
GRCm38.p6 Ensembl1169,498,311 - 169,531,428 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111368   ⟹   ENSMUSP00000106999
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,325,503 - 169,359,033 (-)Ensembl
GRCm38.p6 Ensembl1169,497,934 - 169,531,464 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192248   ⟹   ENSMUSP00000141427
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,337,686 - 169,358,980 (-)Ensembl
GRCm38.p6 Ensembl1169,510,117 - 169,531,411 (-)Ensembl
RefSeq Acc Id: ENSMUST00000194831
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,352,590 - 169,358,987 (-)Ensembl
GRCm38.p6 Ensembl1169,525,021 - 169,531,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000195342   ⟹   ENSMUSP00000141319
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,333,666 - 169,349,951 (-)Ensembl
GRCm38.p6 Ensembl1169,506,097 - 169,522,382 (-)Ensembl
RefSeq Acc Id: NM_001355159   ⟹   NP_001342088
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,325,503 - 169,359,033 (-)NCBI
GRCm381169,497,934 - 169,531,464 (-)NCBI
Sequence:
RefSeq Acc Id: NM_023284   ⟹   NP_075773
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,325,503 - 169,359,033 (-)NCBI
GRCm381169,497,934 - 169,531,464 (-)ENTREZGENE
MGSCv371171,428,065 - 171,461,595 (-)RGD
Celera1171,916,559 - 171,956,575 (-)RGD
cM Map1 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_075773   ⟸   NM_023284
- UniProtKB: Q99P69 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001342088   ⟸   NM_001355159
RefSeq Acc Id: ENSMUSP00000106999   ⟸   ENSMUST00000111368
RefSeq Acc Id: ENSMUSP00000028000   ⟸   ENSMUST00000028000
RefSeq Acc Id: ENSMUSP00000141427   ⟸   ENSMUST00000192248
RefSeq Acc Id: ENSMUSP00000141319   ⟸   ENSMUST00000195342

Promoters
RGD ID:6875598
Promoter ID:EPDNEW_M1250
Type:initiation region
Name:Nuf2_1
Description:Mus musculus NUF2, NDC80 kinetochore complex component , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381169,531,408 - 169,531,468EPDNEW
RGD ID:6818193
Promoter ID:MM_KWN:2766
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000111363,   NM_023284,   UC007DLK.1,   UC007DLL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361171,461,566 - 171,462,066 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914227 AgrOrtholog
Ensembl Genes ENSMUSG00000026683 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000028000 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000106999 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141319 UniProtKB/TrEMBL
  ENSMUSP00000141427 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000028000 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000111368 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000192248 UniProtKB/TrEMBL
  ENSMUST00000195342 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinetochore_Nuf2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuf2_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66977 UniProtKB/Swiss-Prot
MGD MGI:1914227 ENTREZGENE
NCBI Gene 66977 ENTREZGENE
Pfam Nuf2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nuf2 PhenoGen
UniProt A0A0A6YVY5_MOUSE UniProtKB/TrEMBL
  A0A0A6YW74_MOUSE UniProtKB/TrEMBL
  NUF2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8BTK7 UniProtKB/Swiss-Prot
  Q8VE05 UniProtKB/Swiss-Prot
  Q9CST5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Nuf2  NUF2, NDC80 kinetochore complex component    NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED