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Gene: Sigmar1 (sigma non-opioid intracellular receptor 1) Mus musculus
Symbol: Sigmar1
Name: sigma non-opioid intracellular receptor 1
Description: Exhibits signaling receptor activity. Involved in cell death in response to hydrogen peroxide. Localizes to postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; intraembryonic coelom; and liver. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AL024364; mSig; mSigmaR1; O; opioid receptor, sigma 1; Oprs1; Si; Sig1R; sigma 1 receptor variant SR-1D; sigma 1-type opioid receptor; sigma1-receptor; sigma1R
Homo sapiens (human) : SIGMAR1 (sigma non-opioid intracellular receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sigmar1 (sigma non-opioid intracellular receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sigmar1 (sigma non-opioid intracellular receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Canis lupus familiaris (dog) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sigmar1 (sigma non-opioid intracellular receptor 1)
Sus scrofa (pig) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Heterocephalus glaber (naked mole-rat) : Sigmar1 (sigma non-opioid intracellular receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl441,738,493 - 41,756,157 (-)EnsemblGRCm38mm10GRCm38
GRCm38441,738,493 - 41,741,359 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37441,685,369 - 41,688,186 (-)NCBIGRCm37mm9NCBIm37
MGSCv36441,927,007 - 41,929,824 (-)NCBImm8
Celera441,399,281 - 41,402,095 (-)NCBICelera
Cytogenetic Map4A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sigmar1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68520
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.