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Gene: Apln (apelin) Mus musculus
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Symbol: Apln
Name: apelin
Description: Predicted to have apelin receptor binding activity; hormone activity; and protein homodimerization activity. Involved in apelin receptor signaling pathway; coronary vasculature development; and positive regulation of G protein-coupled receptor internalization. Predicted to localize to the extracellular space and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in congestive heart failure. Is expressed in several structures, including central nervous system; genitourinary system; gut; pericardium; and trunk. Orthologous to human APLN (apelin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6030430G11Rik; Apel; APJ endogenous ligand; preproapelin
Orthologs:
Homo sapiens (human) : APLN (apelin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apln (apelin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apln (apelin)
Pan paniscus (bonobo/pygmy chimpanzee) : APLN (apelin)
Canis lupus familiaris (dog) : APLN (apelin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apln (apelin)
Sus scrofa (pig) : APLN (apelin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38X48,025,146 - 48,034,853 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X45,378,323 - 45,388,029 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X44,269,773 - 44,279,461 (-)NCBImm8
CeleraX35,527,952 - 35,537,661 (-)NCBICelera
Cytogenetic MapX A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Apln
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332289
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.