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Gene: Il5 (interleukin 5) Mus musculus
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Symbol: Il5
Name: interleukin 5
Description: Exhibits cytokine activity. Involved in positive regulation of immunoglobulin secretion; positive regulation of peptidyl-tyrosine phosphorylation; and regulation of transcription, DNA-templated. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in asthma. Is expressed in colon; thymus; and thymus primordium. Orthologous to human IL5 (interleukin 5); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; interleukin-4 signaling pathway; interleukin-5 signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell growth factor II; BCGF-II; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor; Il-5; interleukin-5; T-cell replacing factor; TRF
Orthologs:
Homo sapiens (human) : IL5 (interleukin 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il5 (interleukin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il5 (interleukin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : IL5 (interleukin 5)
Canis lupus familiaris (dog) : IL5 (interleukin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il5 (interleukin 5)
Sus scrofa (pig) : IL5 (interleukin 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1153,720,794 - 53,725,106 (+)Ensembl
GRCm381153,720,794 - 53,725,103 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371153,534,296 - 53,538,605 (+)NCBIGRCm37mm9NCBIm37
MGSCv361153,564,217 - 53,568,526 (+)NCBImm8
Celera1158,300,334 - 58,304,644 (+)NCBICelera
Cytogenetic Map11 B1.3NCBI
cM Map1131.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Il5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10799
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.