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Gene: IL5 (interleukin 5) Homo sapiens
Symbol: IL5
Name: interleukin 5
Description: Predicted to have cytokine activity; growth factor activity; and interleukin-5 receptor binding activity. Involved in positive regulation of podosome assembly. Localizes to the extracellular region. Implicated in asthma. Biomarker of several diseases, including Churg-Strauss syndrome; Henoch-Schoenlein purpura; arthritis (multiple); asthma (multiple); and lymphocytic leukemia (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B cell differentiation factor I; B-cell differentiation factor I; colony-stimulating factor, eosinophil; EDF; eosinophil differentiation factor; IL-5; interleukin-5; T-cell replacing factor; TRF
Mus musculus (house mouse) : Il5 (interleukin 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il5 (interleukin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il5 (interleukin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : IL5 (interleukin 5)
Canis lupus familiaris (dog) : IL5 (interleukin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il5 (interleukin 5)
Sus scrofa (pig) : IL5 (interleukin 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl5132,541,445 - 132,556,838 (-)Ensembl
GRCh385132,539,194 - 132,556,864 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,877,136 - 131,892,555 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,905,035 - 131,907,113 (-)NCBINCBI36hg18NCBI36
Build 345131,905,034 - 131,907,113NCBI
Celera5128,007,258 - 128,009,336 (-)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,069,401 - 127,071,479 (-)NCBIHuRef
CHM1_15131,310,410 - 131,312,488 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IL5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730927
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.