Scd1 (stearoyl-Coenzyme A desaturase 1) - Rat Genome Database
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Gene: Scd1 (stearoyl-Coenzyme A desaturase 1) Mus musculus
Analyze
Symbol: Scd1
Name: stearoyl-Coenzyme A desaturase 1
RGD ID: 736587
MGI Page MGI
Description: Exhibits metal ion binding activity; palmitoyl-CoA 9-desaturase activity; and stearoyl-CoA 9-desaturase activity. Involved in several processes, including brown fat cell differentiation; cholesterol esterification; and monounsaturated fatty acid biosynthetic process. Localizes to integral component of endoplasmic reticulum membrane. Is expressed in several structures, including adipose tissue; central nervous system; cranium; integumental system; and liver. Orthologous to several human genes including SCD (stearoyl-CoA desaturase); PARTICIPATES IN fatty acid metabolic pathway; INTERACTS WITH (RS)-coclaurine; (RS)-norcoclaurine; (S)-coclaurine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA589638; ab; acyl-CoA desaturase 1; AI265570; asebia; delta(9)-desaturase 1; delta-9 desaturase 1; fatty acid desaturase 1; SC; Scd; Scd-; Scd-1; stearoyl-CoA desaturase 1
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391944,382,889 - 44,396,148 (-)NCBIGRCm39mm39
GRCm381944,394,450 - 44,407,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1944,394,455 - 44,407,879 (-)EnsemblGRCm38mm10GRCm38
MGSCv371944,468,940 - 44,482,199 (-)NCBIGRCm37mm9NCBIm37
MGSCv361944,447,766 - 44,460,864 (-)NCBImm8
Celera1945,168,530 - 45,181,736 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1937.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-noradrenaline  (ISO)
(RS)-coclaurine  (EXP)
(RS)-norcoclaurine  (EXP)
(S)-coclaurine  (EXP)
(S)-nicotine  (EXP)
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose  (EXP)
1,2,3-trilinolenoylglycerol  (EXP)
1,2,3-trilinoleoylglycerol  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrophenol  (EXP)
2,4-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3,7-dihydropurine-6-thione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-phenylprop-2-enal  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-tert-Octylphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
9-cis,11-trans-octadecadienoic acid  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
Actein  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
andrographolide  (EXP)
Aroclor 1254  (EXP)
arsenous acid  (EXP)
atorvastatin calcium  (ISO)
atrazine  (EXP)
barium sulfate  (ISO)
benomyl  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP)
benzo[b]fluoranthene  (EXP)
benzofurans  (EXP)
benzylpenicillin  (EXP)
beta-hexachlorocyclohexane  (EXP)
beta-naphthoflavone  (EXP)
bexarotene  (EXP,ISO)
bezafibrate  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
buspirone  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (ISO)
caffeine  (EXP,ISO)
carbon nanotube  (EXP)
ceric oxide  (ISO)
chenodeoxycholic acid  (EXP)
chloroprene  (EXP,ISO)
chloroquine  (ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP)
choline  (EXP)
chrysene  (EXP)
cisplatin  (EXP,ISO)
clobetasol  (EXP)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
coumarin  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (EXP)
D-glucose  (EXP,ISO)
DDE  (EXP,ISO)
desmosterol  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP)
diethyl maleate  (ISO)
dioxygen  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
Elemicin  (EXP)
endosulfan  (ISO)
erythromycin A  (EXP)
ethanol  (EXP,ISO)
Ethyl icosapentate  (EXP)
fenarimol  (ISO)
fenofibrate  (EXP,ISO)
fipronil  (ISO)
flutamide  (ISO)
folic acid  (EXP)
fructose  (EXP,ISO)
furan  (ISO)
gadolinium trichloride  (EXP,ISO)
gamma-hexachlorocyclohexane  (ISO)
gemfibrozil  (EXP,ISO)
ginsenoside Re  (EXP)
glucagon  (EXP)
glucose  (EXP,ISO)
glutathione  (ISO)
glycerol 2-phosphate  (EXP)
glycidol  (ISO)
glycine betaine  (ISO)
glyphosate  (EXP)
guggulsterone  (EXP)
GW 3965  (EXP)
Heptachlor epoxide  (EXP)
hexadecanoic acid  (EXP,ISO)
Honokiol  (ISO)
hydrazine  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
ketamine  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (EXP)
L-methionine  (EXP)
lead diacetate  (EXP)
limonene  (ISO)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (EXP)
lovastatin  (EXP)
lutein  (EXP)
manganese(II) chloride  (ISO)
mercaptopurine  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
miconazole  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide  (EXP)
N-acetyl-L-cysteine  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nicotine  (EXP)
nimesulide  (ISO)
octadecanoic acid  (ISO)
oleic acid  (EXP)
orphenadrine  (ISO)
ozone  (EXP,ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorobutyric acid  (EXP)
perfluorodecanoic acid  (EXP)
perfluorododecanoic acid  (ISO)
perfluoroheptanoic acid  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
PhIP  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
potassium bromate  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (EXP)
propamocarb  (EXP)
propiconazole  (EXP,ISO)
purine-6-thiol  (ISO)
PX-866  (EXP)
Pyridostigmine bromide  (ISO)
reactive oxygen species  (ISO)
rebaudioside A  (EXP)
resveratrol  (EXP,ISO)
rifampicin  (EXP)
ritodrine  (EXP)
rotenone  (ISO)
sodium arsenite  (EXP)
sodium cholate  (EXP)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
starch  (EXP)
steviol  (EXP)
stevioside  (EXP)
streptozocin  (EXP)
sucrose  (EXP,ISO)
tamoxifen  (EXP,ISO)
taurine  (EXP)
tauroursodeoxycholic acid  (ISO)
Tesaglitazar  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
tetraphene  (EXP)
thioacetamide  (EXP,ISO)
titanium dioxide  (EXP,ISO)
tolcapone  (ISO)
topiramate  (ISO)
tremolite asbestos  (EXP)
triarachidonin  (EXP)
tributylstannane  (EXP)
Tributyltin oxide  (EXP)
trichloroethene  (EXP,ISO)
triclocarban  (ISO)
triolein  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (EXP,ISO)
trovafloxacin  (ISO)
tunicamycin  (EXP)
valdecoxib  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
yohimbine  (EXP)
zaragozic acid A  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cholesterol homeostasis  (IAGP)
abnormal circulating cholesterol level  (IAGP)
abnormal cutaneous collagen fibril morphology  (IAGP)
abnormal cutaneous elastic fiber morphology  (IAGP)
abnormal dermal layer morphology  (IAGP)
abnormal eating behavior  (IAGP)
abnormal epididymal fat pad morphology  (IAGP)
abnormal estrous cycle  (IEA)
abnormal fat pad morphology  (IAGP)
abnormal gluconeogenesis  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal hair cycle  (IAGP)
abnormal hair follicle bulb morphology  (IAGP)
abnormal hair follicle development  (IEA)
abnormal hair follicle inner root sheath morphology  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal hair follicle outer root sheath morphology  (IAGP)
abnormal hair growth  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal lipid level  (IAGP)
abnormal liver physiology  (IAGP)
abnormal metabolism  (IEA)
abnormal piliary canal morphology  (IEA)
abnormal reproductive system physiology  (IEA)
abnormal sebaceous lipid secretion  (IAGP)
abnormal sebocyte morphology  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin morphology  (IAGP)
abnormal skin physiology  (IAGP)
abnormal skin sebaceous gland morphology  (IAGP)
abnormal triglyceride level  (IAGP)
abnormal uterine fat pad morphology  (IAGP)
acanthosis  (IAGP)
alopecia  (IAGP)
blindness  (IEA)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased circulating VLDL cholesterol level  (IAGP)
decreased circulating VLDL triglyceride level  (IAGP)
decreased gonadal fat pad weight  (IAGP)
decreased hair follicle number  (IEA)
decreased inguinal fat pad weight  (IAGP)
decreased liver glycogen level  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased retroperitoneal fat pad weight  (IAGP)
decreased skin tensile strength  (IAGP)
decreased susceptibility to diet-induced obesity  (IAGP)
decreased susceptibility to hepatic steatosis  (IAGP)
decreased triglyceride level  (IAGP)
decreased unsaturated fatty acids level  (IAGP)
decreased white adipose tissue amount  (IAGP)
distorted hair follicle pattern  (IAGP)
dry skin  (IAGP)
enlarged hair follicles  (IAGP)
eyelids fail to open  (IAGP)
flaky skin  (IAGP)
granulomatous inflammation  (IAGP)
hunched posture  (IAGP)
hyperkeratosis  (IAGP)
impaired skin barrier function  (IAGP)
improved glucose tolerance  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating ketone body level  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased insulin sensitivity  (IAGP)
increased oxygen consumption  (IAGP)
increased saturated fatty acids level  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
matted coat  (IAGP)
Meibomian gland atrophy  (IAGP)
narrow eye opening  (IAGP)
orthokeratosis  (IAGP)
parakeratosis  (IAGP)
photophobia  (IEA)
polyphagia  (IAGP)
polyuria  (IAGP)
postnatal growth retardation  (IEA)
progressive hair loss  (IAGP)
prolonged diestrus  (IEA)
reduced female fertility  (IEA)
scaly skin  (IAGP)
sebaceous gland atrophy  (IAGP)
sebaceous gland hypoplasia  (IAGP)
short hair  (IAGP)
slow postnatal weight gain  (IAGP)
small Meibomian gland  (IAGP)
small perianal sebaceous gland  (IAGP)
small sebaceous gland  (IAGP)
sparse hair  (IAGP)
spontaneous skin ulceration  (IAGP)
thick dermal layer  (IAGP)
thick epidermis  (IAGP)
wrinkled skin  (IAGP)
References

Additional References at PubMed
PMID:631559   PMID:1319776   PMID:1322500   PMID:1350282   PMID:1684180   PMID:2013688   PMID:2903162   PMID:3998439   PMID:5774889   PMID:5924301   PMID:7678489   PMID:7738386  
PMID:7803821   PMID:7835879   PMID:8541340   PMID:8729090   PMID:8790349   PMID:8833906   PMID:8889548   PMID:8954132   PMID:9109606   PMID:9155951   PMID:9256466   PMID:9328433  
PMID:9507200   PMID:9689914   PMID:10087301   PMID:10201521   PMID:10349636   PMID:10441746   PMID:10464095   PMID:10484602   PMID:10545106   PMID:10545940   PMID:10854228   PMID:10899171  
PMID:10982846   PMID:11042159   PMID:11076861   PMID:11090130   PMID:11161812   PMID:11172053   PMID:11441127   PMID:11500518   PMID:11533264   PMID:11544199   PMID:12114623   PMID:12177411  
PMID:12364560   PMID:12401889   PMID:12419843   PMID:12454277   PMID:12466851   PMID:12477932   PMID:12588883   PMID:12646202   PMID:12713573   PMID:12815040   PMID:12928439   PMID:12960377  
PMID:14522948   PMID:14579408   PMID:14610273   PMID:14662765   PMID:14668353   PMID:14681479   PMID:14683458   PMID:14755338   PMID:15066988   PMID:15096593   PMID:15180999   PMID:15210843  
PMID:15278437   PMID:15340109   PMID:15489334   PMID:15494611   PMID:15525534   PMID:15562249   PMID:15597075   PMID:15728386   PMID:15829484   PMID:15855315   PMID:15916750   PMID:16040962  
PMID:16141072   PMID:16141073   PMID:16275639   PMID:16368743   PMID:16443825   PMID:16602821   PMID:16801925   PMID:16804073   PMID:16829211   PMID:16829692   PMID:16943421   PMID:17005996  
PMID:17033839   PMID:17127673   PMID:17164424   PMID:17295720   PMID:17369521   PMID:17391062   PMID:17429444   PMID:17496333   PMID:17960025   PMID:18042664   PMID:18054317   PMID:18079124  
PMID:18249173   PMID:18381840   PMID:18492766   PMID:18599738   PMID:18644838   PMID:18719666   PMID:18788462   PMID:18799693   PMID:18832746   PMID:19002112   PMID:19066317   PMID:19095997  
PMID:19119140   PMID:19258494   PMID:19338759   PMID:19429677   PMID:19633360   PMID:19695343   PMID:19787047   PMID:19883709   PMID:19910642   PMID:20363835   PMID:20603810   PMID:20655875  
PMID:20920255   PMID:20923962   PMID:21205794   PMID:21267068   PMID:21478464   PMID:21573029   PMID:21628453   PMID:21658928   PMID:21677750   PMID:21856199   PMID:21862590   PMID:21873635  
PMID:21890736   PMID:21938009   PMID:22055502   PMID:22096492   PMID:22101133   PMID:22318315   PMID:22326222   PMID:22326531   PMID:22431519   PMID:22539624   PMID:22669918   PMID:22871591  
PMID:22872236   PMID:22912899   PMID:22916088   PMID:23012479   PMID:23221600   PMID:23271751   PMID:23451260   PMID:23620511   PMID:23637738   PMID:23727646   PMID:23747827   PMID:23785402  
PMID:23803969   PMID:23867797   PMID:23907538   PMID:23918045   PMID:23941875   PMID:23945440   PMID:24055053   PMID:24069385   PMID:24088802   PMID:24191036   PMID:24296537   PMID:24356954  
PMID:24548407   PMID:24566853   PMID:24684199   PMID:24876128   PMID:25023287   PMID:25130896   PMID:25147951   PMID:25409434   PMID:25555387   PMID:25675381   PMID:25678624   PMID:25959085  
PMID:26074075   PMID:26098317   PMID:26098370   PMID:26416771   PMID:26508642   PMID:26525535   PMID:26685326   PMID:26976120   PMID:27008858   PMID:27133129   PMID:27146480   PMID:27188441  
PMID:27307439   PMID:27312025   PMID:27416896   PMID:27477676   PMID:27609767   PMID:27632198   PMID:27659424   PMID:27689697   PMID:27751891   PMID:27834856   PMID:28143772   PMID:28167773  
PMID:28259688   PMID:28364022   PMID:28397284   PMID:28659287   PMID:28667176   PMID:28724430   PMID:28790196   PMID:29326439   PMID:29385670   PMID:29463801   PMID:29688375   PMID:29965978  
PMID:30063922   PMID:30074985   PMID:30118512   PMID:30139760   PMID:30228991   PMID:30389914   PMID:30470572   PMID:30791926   PMID:30818059   PMID:30845964   PMID:30930246   PMID:31356236  
PMID:31673045   PMID:31690632   PMID:31953260   PMID:31980623   PMID:32035613   PMID:32097464   PMID:32125933  


Genomics

Comparative Map Data
Scd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391944,382,889 - 44,396,148 (-)NCBIGRCm39mm39
GRCm381944,394,450 - 44,407,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1944,394,455 - 44,407,879 (-)EnsemblGRCm38mm10GRCm38
MGSCv371944,468,940 - 44,482,199 (-)NCBIGRCm37mm9NCBIm37
MGSCv361944,447,766 - 44,460,864 (-)NCBImm8
Celera1945,168,530 - 45,181,736 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1937.98NCBI
Scd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01264,159,966 - 264,173,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1264,160,129 - 264,172,729 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01271,602,885 - 271,615,985 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,458,860 - 249,471,460 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11249,717,543 - 249,730,359 (-)NCBI
Celera1239,084,889 - 239,097,489 (-)NCBICelera
Cytogenetic Map1q54NCBI

Position Markers
M21285  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,397,100 - 44,397,256UniSTSGRCm38
MGSCv371944,471,590 - 44,471,746UniSTSGRCm37
Celera1945,171,180 - 45,171,338UniSTS
Cytogenetic Map19C3UniSTS
cM Map1943.0UniSTS
Whitehead_YAC19 UniSTS
D18Mit29  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,407,680 - 44,407,829UniSTSGRCm38
MGSCv371944,482,170 - 44,482,319UniSTSGRCm37
Cytogenetic Map19C3UniSTS
cM Map1835.0UniSTS
cM Map19 UniSTS
Whitehead Genetic1819.7UniSTS
Whitehead_YAC18 UniSTS
D19Mit67  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,397,155 - 44,397,266UniSTSGRCm38
MGSCv371944,471,645 - 44,471,756UniSTSGRCm37
Celera1945,171,235 - 45,171,348UniSTS
Cytogenetic Map19C3UniSTS
cM Map1943.0UniSTS
Whitehead Genetic1932.8UniSTS
D19Mit67.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,397,005 - 44,397,170UniSTSGRCm38
MGSCv371944,471,495 - 44,471,660UniSTSGRCm37
Celera1945,171,085 - 45,171,250UniSTS
Cytogenetic Map19C3UniSTS
cM Map1943.0UniSTS
cM Map19 UniSTS
Whitehead_YAC19 UniSTS
AI265570  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,394,637 - 44,394,876UniSTSGRCm38
MGSCv371944,469,127 - 44,469,366UniSTSGRCm37
Celera1945,168,717 - 45,168,956UniSTS
Cytogenetic Map19C3UniSTS
cM Map1943.0UniSTS
Whitehead/MRC_RH19435.0UniSTS
RH125028  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,395,030 - 44,395,316UniSTSGRCm38
MGSCv371944,469,520 - 44,469,806UniSTSGRCm37
Celera1945,169,110 - 45,169,396UniSTS
Cytogenetic Map19C3UniSTS
cM Map1943.0UniSTS
Scd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371944,471,829 - 44,472,459UniSTSGRCm37
MGSCv371944,472,470 - 44,472,543UniSTSGRCm37
MGSCv371944,419,255 - 44,419,328UniSTSGRCm37
Celera1945,171,421 - 45,172,051UniSTS
Celera1945,172,062 - 45,172,135UniSTS
Celera1945,118,882 - 45,118,955UniSTS
Cytogenetic Map19C3UniSTS
cM Map1943.0UniSTS
D19Nds1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,397,113 - 44,397,283UniSTSGRCm38
MGSCv371944,471,603 - 44,471,773UniSTSGRCm37
Celera1945,171,193 - 45,171,365UniSTS
Cytogenetic Map19C3UniSTS
cM Map1943.0UniSTS
Scd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3UniSTS
Scd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,397,339 - 44,397,969UniSTSGRCm38
MGSCv371944,471,829 - 44,472,459UniSTSGRCm37
Celera1945,171,421 - 45,172,051UniSTS
Cytogenetic Map19C3UniSTS
Scd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381944,397,980 - 44,398,053UniSTSGRCm38
GRCm381944,344,765 - 44,344,838UniSTSGRCm38
MGSCv371944,419,255 - 44,419,328UniSTSGRCm37
MGSCv371944,472,470 - 44,472,543UniSTSGRCm37
Celera1945,172,062 - 45,172,135UniSTS
Celera1945,118,882 - 45,118,955UniSTS
Cytogenetic Map19C3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
14928311Manh85_mmandible shape 85 (mouse)191193738945937389Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191494561648945738Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191593520749935319Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191593520749935319Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191831776252317981Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191831776252317981Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192025691554257062Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192025691554257062Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192139025755390480Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192233596253923073Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192500000059000000Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192543847859438566Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192739715561397266Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2815190961431566Mouse
4141562Pas3b_mpulmonary adenoma susceptibility 3b (mouse)Not determined2977296261431566Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193015278561431566Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193015279261431566Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193015279261431566Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193090944161431566Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193300371961431566Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193396351461431566Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3460834861431566Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193603954446773082Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193676416661431566Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193789455061431566Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193838761861431566Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193919563261431566Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193960763461431566Mouse
1300585Pgia12_mproteoglycan induced arthritis 12 (mouse)Not determined194259842761431566Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1365
Count of miRNA genes:636
Interacting mature miRNAs:814
Transcripts:ENSMUST00000041331
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA881780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF509567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF509570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC114387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC114388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC114417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ885468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU053011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD544724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU017415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000041331   ⟹   ENSMUSP00000036936
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1944,394,455 - 44,407,709 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235741   ⟹   ENSMUSP00000157730
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1944,406,685 - 44,407,879 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236824
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1944,397,993 - 44,406,690 (-)Ensembl
RefSeq Acc Id: NM_009127   ⟹   NP_033153
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391944,382,889 - 44,396,148 (-)NCBI
GRCm381944,394,450 - 44,407,709 (-)ENTREZGENE
MGSCv371944,468,940 - 44,482,199 (-)RGD
Celera1945,168,530 - 45,181,736 (-)RGD
cM Map19 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033153   ⟸   NM_009127
- UniProtKB: P13516 (UniProtKB/Swiss-Prot),   Q547C4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000036936   ⟸   ENSMUST00000041331
RefSeq Acc Id: ENSMUSP00000157730   ⟸   ENSMUST00000235741
Protein Domains
FA_desaturase

Promoters
RGD ID:13679586
Promoter ID:EPDNEW_M23942
Type:multiple initiation site
Name:Scd1_2
Description:Mus musculus stearoyl-Coenzyme A desaturase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23943  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381944,407,561 - 44,407,621EPDNEW
RGD ID:13679588
Promoter ID:EPDNEW_M23943
Type:initiation region
Name:Scd1_1
Description:Mus musculus stearoyl-Coenzyme A desaturase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23942  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381944,407,708 - 44,407,768EPDNEW
RGD ID:6829868
Promoter ID:MM_KWN:27161
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:UC008HPS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361944,469,856 - 44,471,307 (+)MPROMDB
RGD ID:6830385
Promoter ID:MM_KWN:27162
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_009127
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361944,481,856 - 44,483,037 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98239 AgrOrtholog
Ensembl Genes ENSMUSG00000037071 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000036936 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157730 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000041331 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000235741 UniProtKB/TrEMBL
InterPro Acyl-CoA_DS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FA_desaturase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FADS-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98239 ENTREZGENE
NCBI Gene 20249 ENTREZGENE
PANTHER PTHR11351 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FA_desaturase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Scd1 PhenoGen
PRINTS FACDDSATRASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FATTY_ACID_DESATUR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.267377 ENTREZGENE
UniProt A0A494B9N5_MOUSE UniProtKB/TrEMBL
  ACOD1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UXG5_MOUSE UniProtKB/TrEMBL
  Q547C4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q922I6 UniProtKB/Swiss-Prot