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Gene: Lpin1 (lipin 1) Mus musculus
Symbol: Lpin1
Name: lipin 1
Description: Exhibits several functions, including RNA polymerase II transcription factor binding activity; histone deacetylase binding activity; and peroxisome proliferator activated receptor binding activity. Involved in several processes, including positive regulation of cold-induced thermogenesis; regulation of transcription by RNA polymerase II; and triglyceride mobilization. Localizes to the mitochondrial outer membrane; nuclear membrane; and transcription factor complex. Used to study lipodystrophy. Is expressed in liver; nervous system; olfactory epithelium; and tooth. Orthologous to human LPIN1 (lipin 1); INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4631420P06; fatty liver dystrophy protein; fld; Kiaa0188; lipin-1; Lipin1; mKIAA0188; phosphatidate phosphatase LPIN1
Homo sapiens (human) : LPIN1 (lipin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lpin1 (lipin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpin1 (lipin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LPIN1 (lipin 1)
Canis lupus familiaris (dog) : LPIN1 (lipin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpin1 (lipin 1)
Sus scrofa (pig) : LPIN1 (lipin 1)
Chlorocebus sabaeus (green monkey) : LPIN1 (lipin 1)
Heterocephalus glaber (naked mole-rat) : Lpin1 (lipin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1216,535,669 - 16,646,966 (-)Ensembl
GRCm381216,535,669 - 16,653,903 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371216,542,475 - 16,596,576 (-)NCBIGRCm37mm9NCBIm37
MGSCv361216,562,116 - 16,615,250 (-)NCBImm8
Celera1216,861,042 - 16,914,762 (-)NCBICelera
Cytogenetic Map12 A1.1NCBI
cM Map127.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lpin1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316958
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.