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Gene: Lpin1 (lipin 1) Mus musculus
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Symbol: Lpin1
Name: lipin 1
Description: Exhibits several functions, including RNA polymerase II transcription factor binding activity; histone deacetylase binding activity; and peroxisome proliferator activated receptor binding activity. Involved in several processes, including positive regulation of cold-induced thermogenesis; regulation of transcription by RNA polymerase II; and triglyceride mobilization. Localizes to the mitochondrial outer membrane; nuclear membrane; and transcription factor complex. Used to study lipodystrophy. Is expressed in liver; nervous system; olfactory epithelium; and tooth. Orthologous to human LPIN1 (lipin 1); INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4631420P06; fatty liver dystrophy protein; fld; Kiaa0188; lipin-1; Lipin1; mKIAA0188; phosphatidate phosphatase LPIN1
Orthologs:
Homo sapiens (human) : LPIN1 (lipin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lpin1 (lipin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpin1 (lipin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LPIN1 (lipin 1)
Canis lupus familiaris (dog) : LPIN1 (lipin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpin1 (lipin 1)
Sus scrofa (pig) : LPIN1 (lipin 1)
Chlorocebus sabaeus (green monkey) : LPIN1 (lipin 1)
Heterocephalus glaber (naked mole-rat) : Lpin1 (lipin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1216,535,669 - 16,646,966 (-)Ensembl
GRCm381216,535,669 - 16,653,903 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371216,542,475 - 16,596,576 (-)NCBIGRCm37mm9NCBIm37
MGSCv361216,562,116 - 16,615,250 (-)NCBImm8
Celera1216,861,042 - 16,914,762 (-)NCBICelera
Cytogenetic Map12 A1.1NCBI
cM Map127.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lpin1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316958
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.