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Gene: Ereg (epiregulin) Mus musculus
Symbol: Ereg
Name: epiregulin
RGD ID: 730899
Description: Exhibits epidermal growth factor receptor binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of macromolecule metabolic process; and positive regulation of mitotic nuclear division. Localizes to extracellular space. Is expressed in several structures, including brain; extraembryonic component; lung; ovary; and skin. Orthologous to human EREG (epiregulin); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E; EPR; MGC36144; proepiregulin
Homo sapiens (human) : EREG (epiregulin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ereg (epiregulin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ereg (epiregulin)
Pan paniscus (bonobo/pygmy chimpanzee) : EREG (epiregulin)
Canis lupus familiaris (dog) : EREG (epiregulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ereg (epiregulin)
Sus scrofa (pig) : EREG (epiregulin)
Chlorocebus sabaeus (African green monkey) : EREG (epiregulin)
Heterocephalus glaber (naked mole-rat) : Ereg (epiregulin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39591,222,476 - 91,241,508 (+)NCBI
GRCm38591,074,617 - 91,093,649 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl591,074,622 - 91,093,646 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,503,643 - 91,522,675 (+)NCBIGRCm37mm9NCBIm37
MGSCv36592,149,822 - 92,168,846 (+)NCBImm8
Celera589,212,781 - 89,230,978 (+)NCBICelera
Cytogenetic Map5E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ereg
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730899
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.