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Gene: Lifr (LIF receptor alpha) Mus musculus
Symbol: Lifr
Name: LIF receptor alpha
Description: Predicted to contribute to leukemia inhibitory factor receptor activity and oncostatin-M receptor activity. Involved in positive regulation of cell population proliferation. Localizes to the extracellular space. Used to study CAKUT. Human ortholog(s) of this gene implicated in osteochondrodysplasia. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and immune system. Orthologous to human LIFR (LIF receptor subunit alpha); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A230075M04Rik; AW061234; D-factor/LIF receptor; expressed sequence AW061234; leukemia inhibitory factor receptor; leukemia inhibitory factor receptor alpha chain; LIF; LIF receptor; LIF-R; RIKEN cDNA A230075M04 gene; soluble differentiation-stimulating factor receptor
Homo sapiens (human) : LIFR (LIF receptor subunit alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lifr (LIF receptor subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lifr (LIF receptor subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : LIFR (LIF receptor subunit alpha)
Canis lupus familiaris (dog) : LIFR (LIF receptor subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lifr (LIF receptor subunit alpha)
Sus scrofa (pig) : LOC102167255 (leukemia inhibitory factor receptor)
Chlorocebus sabaeus (green monkey) : LIFR (LIF receptor subunit alpha)
Heterocephalus glaber (naked mole-rat) : Lifr (LIF receptor subunit alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl157,090,614 - 7,197,489 (+)Ensembl
GRCm38157,090,610 - 7,197,489 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37157,079,572 - 7,147,489 (+)NCBIGRCm37mm9NCBIm37
MGSCv36157,087,757 - 7,138,433 (+)NCBImm8
Celera156,977,793 - 7,045,762 (+)NCBICelera
Cytogenetic Map15 A1NCBI
cM Map153.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Lifr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732565
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.