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Gene: Parp1 (poly (ADP-ribose) polymerase family, member 1) Mus musculus
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Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Description: Exhibits NAD+ ADP-ribosyltransferase activity; chromatin binding activity; and protein ADP-ribosylase activity. Involved in several processes, including DNA metabolic process; behavioral response to cocaine; and regulation of DNA metabolic process. Localizes to the cytoplasm; nuclear lumen; and protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including arthritis; bacterial meningitis; neurodegenerative disease (multiple); stomach carcinoma; and type 2 diabetes mellitus. Is expressed in several structures, including Peyer's patch; brain; gut; immune system; and retina. Orthologous to human PARP1 (poly(ADP-ribose) polymerase 1); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; base excision repair pathway; INTERACTS WITH (+)-catechin; (+)-dexrazoxane; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5830444G22Rik; ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase diphtheria toxin-like 1; Adprp; ADPRT 1; Adprt1; AI893648; ARTD1; C80510; DNA ADP-ribosyltransferase PARP1; msPARP; NAD(+) ADP-ribosyltransferase 1; PARP; parp-1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; sPARP-1
Orthologs:
Homo sapiens (human) : PARP1 (poly(ADP-ribose) polymerase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Parp1 (poly (ADP-ribose) polymerase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Parp1 (poly(ADP-ribose) polymerase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PARP1 (poly(ADP-ribose) polymerase 1)
Canis lupus familiaris (dog) : PARP1 (poly(ADP-ribose) polymerase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Parp1 (poly(ADP-ribose) polymerase 1)
Sus scrofa (pig) : PARP1 (poly(ADP-ribose) polymerase 1)
Chlorocebus sabaeus (green monkey) : PARP1 (poly(ADP-ribose) polymerase 1)
Heterocephalus glaber (naked mole-rat) : Parp1 (poly(ADP-ribose) polymerase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1180,568,924 - 180,601,254 (+)Ensembl
GRCm381180,568,891 - 180,600,999 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371182,499,106 - 182,531,385 (+)NCBIGRCm37mm9NCBIm37
MGSCv361182,405,650 - 182,437,929 (+)NCBImm8
Celera1187,634,811 - 187,667,071 (+)NCBICelera
Cytogenetic Map1 H4NCBI
cM Map184.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model