Parp1 (poly (ADP-ribose) polymerase family, member 1) - Rat Genome Database
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Gene: Parp1 (poly (ADP-ribose) polymerase family, member 1) Mus musculus
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Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
RGD ID: 1551988
MGI Page MGI
Description: Exhibits NAD+ ADP-ribosyltransferase activity; chromatin binding activity; and protein ADP-ribosylase activity. Involved in several processes, including DNA metabolic process; behavioral response to cocaine; and regulation of DNA metabolic process. Localizes to cytoplasm; nuclear lumen; and protein-containing complex. Is expressed in several structures, including Peyer's patch; brain; gut; immune system; and retina. Human ortholog(s) of this gene implicated in several diseases, including arthritis; asthma; bacterial meningitis; neurodegenerative disease (multiple); and stomach carcinoma. Orthologous to human PARP1 (poly(ADP-ribose) polymerase 1); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; base excision repair pathway; INTERACTS WITH (+)-catechin; (+)-dexrazoxane; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5830444G22Rik; A; Adp; ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase diphtheria toxin-like 1; Adprp; ADPRT 1; Adprt1; AI893648; ARTD1; C80510; DNA ADP-ribosyltransferase PARP1; msPARP; NAD(+) ADP-ribosyltransferase 1; pa; PARP; parp-1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; sP; sPARP-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,396,456 - 180,428,564 (+)NCBIGRCm39mm39
GRCm381180,568,891 - 180,600,999 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,568,924 - 180,601,254 (+)EnsemblGRCm38mm10GRCm38
MGSCv371182,499,106 - 182,531,385 (+)NCBIGRCm37mm9NCBIm37
MGSCv361182,405,650 - 182,437,929 (+)NCBImm8
Celera1187,634,811 - 187,667,071 (+)NCBICelera
Cytogenetic Map1H4NCBI
cM Map184.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model