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Gene: Prkcd (protein kinase C, delta) Mus musculus
Symbol: Prkcd
Name: protein kinase C, delta
Description: Exhibits insulin receptor substrate binding activity and protein kinase C activity. Involved in several processes, including cytokine production; negative regulation of cellular component organization; and regulation of signal transduction. Localizes to several cellular components, including cell-cell junction; cytoplasm; and nuclear matrix. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and heart and pericardium. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3; fatty liver disease; and hypertension. Orthologous to human PRKCD (protein kinase C delta); PARTICIPATES IN ceramide signaling pathway; eicosanoid signaling pathway; endothelin signaling pathway; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI385711; D14Ertd420e; nPKC-delta; PKC[d]; Pkcd; PKCdelta; protein kinase C delta type; protein kinase C delta variant IX; protein kinase C, delta IV; protein kinase C, delta V; protein kinase C[d]; tyrosine-protein kinase PRKCD
Homo sapiens (human) : PRKCD (protein kinase C delta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prkcd (protein kinase C, delta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcd (protein kinase C delta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCD (protein kinase C delta)
Canis lupus familiaris (dog) : PRKCD (protein kinase C delta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcd (protein kinase C delta)
Sus scrofa (pig) : PRKCD (protein kinase C delta)
Chlorocebus sabaeus (African green monkey) : PRKCD (protein kinase C delta)
Heterocephalus glaber (naked mole-rat) : Prkcd (protein kinase C delta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1430,595,354 - 30,626,210 (-)EnsemblGRCm38mm10GRCm38
GRCm381430,595,353 - 30,626,414 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371431,408,555 - 31,423,498 (-)NCBIGRCm37mm9NCBIm37
MGSCv361429,424,378 - 29,447,560 (-)NCBImm8
Celera1426,853,019 - 26,867,962 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1418.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prkcd
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69027
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.