Prkcd (protein kinase C, delta) - Rat Genome Database

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Gene: Prkcd (protein kinase C, delta) Mus musculus
Analyze
Symbol: Prkcd
Name: protein kinase C, delta
RGD ID: 69027
MGI Page MGI
Description: Enables diacylglycerol-dependent serine/threonine kinase activity and insulin receptor substrate binding activity. Involved in several processes, including negative regulation of cellular component organization; negative regulation of insulin receptor signaling pathway; and negative regulation of platelet aggregation. Acts upstream of or within B cell proliferation; immunoglobulin mediated immune response; and positive regulation of apoptotic signaling pathway. Located in several cellular components, including cell-cell junction; cytoplasm; and nuclear matrix. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and heart and pericardium. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3; hypertension; and steatotic liver disease. Orthologous to human PRKCD (protein kinase C delta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI385711; D14Ertd420; D14Ertd420e; nPKC-delta; Pkc; PKC[d; PKC[d]; Pkcd; PKCde; PKCdelta; protein kinase C delta type; protein kinase C delta variant IX; protein kinase C, delta IV; protein kinase C, delta V; protein kinase C[d]; tyrosine-protein kinase PRKCD
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,317,310 - 30,348,637 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,317,311 - 30,348,167 (-)EnsemblGRCm39 Ensembl
GRCm381430,595,353 - 30,626,414 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,595,354 - 30,626,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv371431,408,555 - 31,423,498 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361429,424,378 - 29,447,560 (-)NCBIMGSCv36mm8
Celera1426,853,019 - 26,867,962 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1418.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-amphetamine  (ISO)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (EXP)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (EXP)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-nitropropanoic acid  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
6-formylpterin  (ISO)
6-propyl-2-thiouracil  (ISO)
8-OH-DPAT  (EXP)
acetaldehyde  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
allyl alcohol  (ISO)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apocynin  (EXP,ISO)
aripiprazole  (ISO)
arjunolic acid  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
Bay-K-8644  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisdemethoxycurcumin  (EXP)
bisoprolol  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bortezomib  (ISO)
brimonidine tartrate  (ISO)
bromocriptine  (ISO)
butorphanol  (ISO)
butylated hydroxyanisole  (ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
Calcimycin  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
Calphostin C  (ISO)
capsaicin  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
carvedilol  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (EXP)
ciglitazone  (ISO)
cisplatin  (EXP,ISO)
citalopram  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (EXP)
crotonaldehyde  (ISO)
curcumin  (ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP)
D-glucose  (ISO)
D-mannitol  (ISO)
daidzein  (ISO)
daunorubicin  (ISO)
demethoxycurcumin  (EXP)
desferrioxamine B  (ISO)
dextromethorphan  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenziodolium  (ISO)
dibutyl phthalate  (EXP,ISO)
dieldrin  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
disodium selenite  (EXP)
divanadium pentaoxide  (EXP,ISO)
dopamine  (EXP)
doxorubicin  (ISO)
emodin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
etoposide  (ISO)
fenamidone  (EXP)
folic acid  (EXP)
folpet  (EXP)
fomepizole  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (ISO)
ginsenoside Re  (EXP,ISO)
glucose  (ISO)
glutathione  (EXP,ISO)
heptachlor  (ISO)
hexadecanoic acid  (ISO)
histamine  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (EXP,ISO)
irinotecan  (ISO)
isoprenaline  (ISO)
isorhamnetin  (ISO)
ivermectin  (ISO)
kainic acid  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (EXP)
lovastatin  (ISO)
LY294002  (ISO)
magnesium atom  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP,ISO)
methotrexate  (ISO)
methyl beta-cyclodextrin  (ISO)
mevalonic acid  (ISO)
microcystin-LR  (EXP)
mitomycin C  (ISO)
morphine  (EXP)
Morroniside  (ISO)
motexafin gadolinium  (ISO)
myo-inositol hexakisphosphate  (ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
naringin  (ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
nicotine  (EXP)
nitric oxide  (ISO)
oroxylin A  (ISO)
oxidopamine  (EXP,ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
phencyclidine  (EXP)
phenylephrine  (ISO)
phorbol 12,13-dibutanoate  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
picrotoxin  (ISO)
potassium cyanide  (EXP)
progesterone  (EXP,ISO)
propofol  (ISO)
propranolol  (ISO)
puerarin  (EXP)
quercetin  (EXP,ISO)
reactive oxygen species  (EXP,ISO)
resveratrol  (ISO)
rotenone  (ISO)
rottlerin  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
staurosporine  (ISO)
streptozocin  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP)
taurine  (ISO)
testosterone  (EXP,ISO)
tetraphene  (ISO)
thalidomide  (ISO)
thapsigargin  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
trimethyltin  (EXP)
triptonide  (EXP)
tungsten  (EXP)
tyrphostin AG 1478  (ISO)
U-73122  (ISO)
U50488  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
wortmannin  (ISO)
Yessotoxin  (ISO)
zinc acetate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (ISO)
B cell proliferation  (IMP)
cell chemotaxis  (ISO)
cellular response to angiotensin  (ISO)
cellular response to glucose starvation  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hydroperoxide  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to oxidative stress  (ISO)
cellular response to UV  (ISO)
cellular senescence  (ISO)
collagen metabolic process  (ISO)
D-aspartate import across plasma membrane  (ISO)
defense response to bacterium  (IMP)
DNA damage response  (ISO)
immunoglobulin mediated immune response  (IMP)
intracellular signal transduction  (IBA,ISO)
negative regulation of actin filament polymerization  (IMP)
negative regulation of filopodium assembly  (IMP)
negative regulation of glial cell apoptotic process  (ISO)
negative regulation of insulin receptor signaling pathway  (IMP)
negative regulation of peptidyl-tyrosine phosphorylation  (IMP)
negative regulation of platelet aggregation  (IMP)
neutrophil activation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of apoptotic signaling pathway  (IDA)
positive regulation of ceramide biosynthetic process  (ISO)
positive regulation of glucose import  (ISO)
positive regulation of glucosylceramide catabolic process  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of protein dephosphorylation  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of sphingomyelin catabolic process  (ISO)
positive regulation of superoxide anion generation  (ISO)
post-translational protein modification  (ISO)
protein autophosphorylation  (ISO)
protein phosphorylation  (ISO)
regulation of actin cytoskeleton organization  (ISO)
regulation of ceramide biosynthetic process  (ISO)
regulation of phosphorylation  (ISO)
response to amino acid  (ISO)
response to ethanol  (ISO)
response to glucose  (ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (ISO)
response to mechanical stimulus  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to oxidative stress  (ISO)
response to xenobiotic stimulus  (ISO)
termination of signal transduction  (ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell physiology  (IAGP)
abnormal B cell proliferation  (IAGP)
abnormal bone ossification  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal immunoglobulin level  (IAGP)
abnormal lymph node germinal center morphology  (IAGP)
abnormal neutrophil physiology  (IAGP)
abnormal osteoblast differentiation  (IAGP)
abnormal pancreatic beta cell morphology  (IAGP)
abnormal Peyer's patch germinal center morphology  (IAGP)
abnormal plasma cell differentiation  (IAGP)
abnormal response to CNS ischemic injury  (IAGP)
abnormal response to transplant  (IAGP)
abnormal self tolerance  (IAGP)
abnormal spleen primary B follicle morphology  (IAGP)
arrested B cell differentiation  (IAGP)
arteriosclerosis  (IAGP)
autoimmune response  (IAGP)
decreased B cell number  (IAGP)
decreased B-1 B cell number  (IAGP)
decreased B-2 B cell number  (IAGP)
decreased body weight  (IAGP)
decreased follicular B cell number  (IAGP)
decreased insulin secretion  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased neutrophil cell number  (IAGP)
decreased width of hypertrophic chondrocyte zone  (IAGP)
enhanced humoral immune response  (IEA)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
glomerulonephritis  (IAGP)
impaired glucose tolerance  (IAGP)
improved glucose tolerance  (IAGP)
increased acute inflammation  (IAGP)
increased anti-chromatin antibody level  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased B cell apoptosis  (IAGP)
increased B cell number  (IAGP)
increased B cell proliferation  (IAGP)
increased erythrocyte cell number  (IAGP)
increased follicular B cell number  (IAGP)
increased IgA level  (IAGP)
increased IgG1 level  (IAGP)
increased IgG2b level  (IAGP)
increased IgG3 level  (IAGP)
increased IgM level  (IAGP)
increased insulin sensitivity  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased marginal zone B cell number  (IAGP)
increased NK cell number  (IEA)
increased spleen germinal center number  (IAGP)
increased susceptibility to induced colitis  (IEA)
increased transitional stage B cell number  (IAGP)
premature death  (IAGP)
renal glomerular immunoglobulin deposits  (IAGP)
vascular smooth muscle hyperplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis. Avignon A, etal., Diabetes. 1996 Oct;45(10):1396-404.
2. Regulation of protein kinase C isozymes in volume overload cardiac hypertrophy. Braun MU, etal., Mol Cell Biochem. 2004 Jul;262(1-2):135-43.
3. DeltaPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo. Bright R, etal., Brain Res. 2007 May 4;1144:146-55. Epub 2007 Feb 2.
4. A systems biology approach to the pathogenesis of obesity-related nonalcoholic fatty liver disease using reverse phase protein microarrays for multiplexed cell signaling analysis. Calvert VS, etal., Hepatology. 2007 Jul;46(1):166-72.
5. Altered cardiac endothelin receptors and protein kinase C in deoxycorticosterone-salt hypertensive rats. Fareh J, etal., J Mol Cell Cardiol. 2000 Apr;32(4):665-76.
6. Changes in protein kinase C in early cardiomyopathy and in gracilis muscle in the BB/Wor diabetic rat. Giles TD, etal., Am J Physiol. 1998 Jan;274(1 Pt 2):H295-307.
7. Activation of protein kinase c-delta and c-epsilon by oxidative stress in early diabetic rat kidney. Ha H, etal., Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S204-7.
8. Protein kinase C isozymes in hypertension and hypertrophy: insight from SHHF rat hearts. Johnsen DD, etal., Mol Cell Biochem. 2005 Feb;270(1-2):63-9.
9. Protective role of intracellular zinc in myocardial ischemia/reperfusion is associated with preservation of protein kinase C isoforms. Karagulova G, etal., J Pharmacol Exp Ther. 2007 May;321(2):517-25. Epub 2007 Feb 22.
10. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
11. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
12. Activation and translocation of PKCdelta is necessary for VEGF-induced ERK activation through KDR in HEK293T cells. Kuriyama M, etal., Biochem Biophys Res Commun. 2004 Dec 17;325(3):843-51.
13. Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-delta. Lam TK, etal., Am J Physiol Endocrinol Metab 2002 Oct;283(4):E682-91.
14. MGDs mouse GO annotations MGD data from the GO Consortium
15. MGD IEA MGD IEA
16. Obesity is associated with impaired ventricular protein kinase C-MAP kinase signaling and altered ANP mRNA expression in the heart of adult Zucker rats. Morabito D, etal., J Investig Med. 2001 Jul;49(4):310-8.
17. Protein kinase C: poised to signal. Newton AC Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E395-402. Epub 2009 Nov 24.
18. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
19. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
20. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
21. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22. Mouse MP Annotation Import Pipeline RGD automated import pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Dual mechanism of autoregulation of protein kinase C in myocardial ischemia. Simonis G, etal., Mol Cell Biochem. 2007 Jan;295(1-2):121-8. Epub 2006 Aug 22.
26. PKC-delta-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase. Talior I, etal., Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E405-11. Epub 2004 Oct 26.
27. Effects of burn injury on myocardial signaling and cytokine secretion: Possible role of PKC. Tan J, etal., Am J Physiol Regul Integr Comp Physiol. 2007 Feb;292(2):R887-96. Epub 2006 Sep 21.
28. Difference in gene expression of macrophage between normal spleen and portal hypertensive spleen identified by cDNA microarray. Yan F and Wang XM, World J Gastroenterol. 2007 Jun 28;13(24):3369-73.
Additional References at PubMed
PMID:1477958   PMID:1508194   PMID:1765103   PMID:1868068   PMID:7499852   PMID:7606770   PMID:7637094   PMID:7781068   PMID:7963691   PMID:7985811   PMID:8106444   PMID:8149484  
PMID:8188219   PMID:8526869   PMID:8663197   PMID:8670164   PMID:8694767   PMID:8889548   PMID:8922669   PMID:8948582   PMID:8995230   PMID:9417917   PMID:9748166   PMID:9828146  
PMID:10349636   PMID:10391924   PMID:10582689   PMID:10879655   PMID:10882525   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11259653   PMID:11544199   PMID:11558579   PMID:11668067  
PMID:11698278   PMID:11714742   PMID:11796722   PMID:11803573   PMID:11812791   PMID:11959144   PMID:11976686   PMID:11976687   PMID:12024011   PMID:12031982   PMID:12032864   PMID:12054751  
PMID:12061781   PMID:12065247   PMID:12117979   PMID:12170178   PMID:12207561   PMID:12361954   PMID:12386152   PMID:12426377   PMID:12477932   PMID:12510148   PMID:12643789   PMID:12761849  
PMID:12765967   PMID:12809676   PMID:12826574   PMID:12826681   PMID:12857675   PMID:14511117   PMID:14527684   PMID:14583092   PMID:14597424   PMID:14610273   PMID:14613966   PMID:14715240  
PMID:14747473   PMID:14966364   PMID:14985469   PMID:15054085   PMID:15068794   PMID:15131007   PMID:15138267   PMID:15156560   PMID:15223313   PMID:15229137   PMID:15232611   PMID:15234976  
PMID:15277208   PMID:15277209   PMID:15289456   PMID:15337529   PMID:15361883   PMID:15540248   PMID:15542581   PMID:15567068   PMID:15585335   PMID:15649703   PMID:15702246   PMID:15731106  
PMID:15735693   PMID:15817708   PMID:15858417   PMID:15907783   PMID:16118209   PMID:16141072   PMID:16141073   PMID:16183862   PMID:16183863   PMID:16314418   PMID:16337250   PMID:16338928  
PMID:16403461   PMID:16418226   PMID:16424000   PMID:16424016   PMID:16452485   PMID:16481047   PMID:16483929   PMID:16503160   PMID:16537572   PMID:16537649   PMID:16571779   PMID:16602821  
PMID:16611985   PMID:16638571   PMID:16735462   PMID:16772297   PMID:16804093   PMID:16930532   PMID:16940418   PMID:16943444   PMID:16950644   PMID:16963224   PMID:17017122   PMID:17043352  
PMID:17098397   PMID:17135234   PMID:17142776   PMID:17161867   PMID:17199045   PMID:17200189   PMID:17219421   PMID:17325386   PMID:17337596   PMID:17346795   PMID:17404251   PMID:17446207  
PMID:17471506   PMID:17507557   PMID:17548619   PMID:17569658   PMID:17574042   PMID:17653823   PMID:17662968   PMID:17704327   PMID:17705133   PMID:17721436   PMID:17728398   PMID:17893151  
PMID:17913887   PMID:18025218   PMID:18059334   PMID:18160487   PMID:18227389   PMID:18285345   PMID:18285444   PMID:18323529   PMID:18471090   PMID:18511573   PMID:18523985   PMID:18602096  
PMID:18722532   PMID:18799693   PMID:18802074   PMID:18836180   PMID:18845574   PMID:18990707   PMID:19001377   PMID:19005054   PMID:19027023   PMID:19029199   PMID:19030108   PMID:19073150  
PMID:19074768   PMID:19075017   PMID:19098423   PMID:19116364   PMID:19146951   PMID:19213940   PMID:19339281   PMID:19401335   PMID:19458393   PMID:19492056   PMID:19554387   PMID:19587372  
PMID:19592494   PMID:19633290   PMID:19752773   PMID:19808702   PMID:19809797   PMID:19850933   PMID:19881493   PMID:19900507   PMID:19914197   PMID:19931912   PMID:19965374   PMID:19966290  
PMID:20110406   PMID:20122929   PMID:20151299   PMID:20221584   PMID:20335173   PMID:20338032   PMID:20388733   PMID:20395372   PMID:20478382   PMID:20512658   PMID:20548952   PMID:20582580  
PMID:20691763   PMID:20798245   PMID:20815813   PMID:20861461   PMID:20884873   PMID:20927330   PMID:20971075   PMID:20971848   PMID:21103982   PMID:21190563   PMID:21267068   PMID:21287553  
PMID:21311042   PMID:21335545   PMID:21346188   PMID:21346196   PMID:21364618   PMID:21440619   PMID:21441934   PMID:21467032   PMID:21491433   PMID:21540297   PMID:21549093   PMID:21576825  
PMID:21633170   PMID:21702866   PMID:21736870   PMID:21812036   PMID:21828049   PMID:21865164   PMID:21873635   PMID:21878493   PMID:21911383   PMID:21920989   PMID:22103274   PMID:22154818  
PMID:22163289   PMID:22216119   PMID:22265677   PMID:22271577   PMID:22275369   PMID:22277757   PMID:22318721   PMID:22374815   PMID:22393041   PMID:22403440   PMID:22456512   PMID:22463764  
PMID:22499584   PMID:22540228   PMID:22609986   PMID:22706318   PMID:22794259   PMID:22806935   PMID:22879584   PMID:22885697   PMID:22983354   PMID:23252604   PMID:23305608   PMID:23322705  
PMID:23326354   PMID:23375831   PMID:23474764   PMID:23557702   PMID:23653351   PMID:23861806   PMID:23896721   PMID:23902767   PMID:23951014   PMID:24155954   PMID:24357731   PMID:24454937  
PMID:24478091   PMID:24515435   PMID:24516390   PMID:24519937   PMID:24569990   PMID:24632809   PMID:24667603   PMID:24682410   PMID:24863469   PMID:24952961   PMID:25035929   PMID:25084151  
PMID:25116170   PMID:25175814   PMID:25253077   PMID:25261467   PMID:25342743   PMID:25359536   PMID:25359855   PMID:25407782   PMID:25445585   PMID:25445591   PMID:25491605   PMID:25505183  
PMID:25563840   PMID:25634144   PMID:25661082   PMID:25692509   PMID:25829232   PMID:25890235   PMID:25900833   PMID:26157004   PMID:26202826   PMID:26275053   PMID:26279273   PMID:26307588  
PMID:26332085   PMID:26335446   PMID:26363783   PMID:26522132   PMID:26641069   PMID:26668311   PMID:26671999   PMID:26707247   PMID:26708502   PMID:26730154   PMID:26832303   PMID:26886171  
PMID:26978024   PMID:27151770   PMID:27348590   PMID:27422101   PMID:27807348   PMID:27841943   PMID:27926862   PMID:28363605   PMID:28378742   PMID:28528205   PMID:28597397   PMID:28832027  
PMID:28921616   PMID:29111976   PMID:29305535   PMID:29388468   PMID:29412702   PMID:29632528   PMID:29669290   PMID:29786085   PMID:30024612   PMID:30095599   PMID:30261270   PMID:30446598  
PMID:30589566   PMID:30679314   PMID:30685263   PMID:30862678   PMID:30997682   PMID:31036561   PMID:31065073   PMID:32142354   PMID:32291286   PMID:32325033   PMID:32542692   PMID:32554809  
PMID:32582715   PMID:32677469   PMID:32759670   PMID:32938907   PMID:33705388   PMID:33722087   PMID:33932405   PMID:33947214   PMID:34108435   PMID:34197550   PMID:34469734   PMID:34693907  
PMID:34860583   PMID:35145231   PMID:35409362   PMID:35502493   PMID:36114006   PMID:36371785   PMID:37890601   PMID:38134280  


Genomics

Comparative Map Data
Prkcd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,317,310 - 30,348,637 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,317,311 - 30,348,167 (-)EnsemblGRCm39 Ensembl
GRCm381430,595,353 - 30,626,414 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,595,354 - 30,626,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv371431,408,555 - 31,423,498 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361429,424,378 - 29,447,560 (-)NCBIMGSCv36mm8
Celera1426,853,019 - 26,867,962 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1418.82NCBI
PRKCD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38353,161,209 - 53,192,717 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl353,156,009 - 53,192,717 (+)EnsemblGRCh38hg38GRCh38
GRCh37353,195,225 - 53,226,733 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36353,170,263 - 53,201,773 (+)NCBINCBI36Build 36hg18NCBI36
Build 34353,170,262 - 53,201,771NCBI
Celera353,162,239 - 53,193,756 (+)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef353,210,511 - 53,276,026 (+)NCBIHuRef
CHM1_1353,146,796 - 53,178,291 (+)NCBICHM1_1
T2T-CHM13v2.0353,194,119 - 53,225,596 (+)NCBIT2T-CHM13v2.0
Prkcd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8165,775,681 - 5,806,122 (-)NCBIGRCr8
mRatBN7.2165,769,217 - 5,799,380 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,769,215 - 5,799,352 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx165,781,205 - 5,811,322 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0166,926,659 - 6,956,775 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,779,783 - 5,809,932 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0166,655,131 - 6,675,746 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,655,120 - 6,675,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0166,588,990 - 6,608,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4165,954,218 - 5,975,743 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1165,954,214 - 5,975,741 (-)NCBI
Celera169,398,816 - 9,419,806 (+)NCBICelera
Cytogenetic Map16p16NCBI
Prkcd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554303,124,738 - 3,153,274 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554303,125,066 - 3,151,857 (+)NCBIChiLan1.0ChiLan1.0
PRKCD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2253,157,598 - 53,189,084 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1353,162,376 - 53,193,855 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0353,104,137 - 53,135,588 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1354,330,328 - 54,357,910 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,330,328 - 54,357,910 (+)Ensemblpanpan1.1panPan2
PRKCD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12036,723,491 - 36,751,982 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2036,723,809 - 36,752,191 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2036,660,459 - 36,673,894 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,001,697 - 37,030,998 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,001,704 - 37,031,073 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12036,438,983 - 36,452,419 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02036,800,686 - 36,814,133 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,015,742 - 37,029,186 (-)NCBIUU_Cfam_GSD_1.0
Prkcd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,754,028 - 170,788,044 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,892,366 - 3,923,515 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,892,625 - 3,923,467 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKCD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,290,610 - 35,323,356 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11335,290,835 - 35,323,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,361,707 - 38,390,508 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKCD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,561,401 - 14,592,877 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2214,565,282 - 14,592,873 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041152,302,998 - 152,334,406 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkcd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,033,130 - 4,059,555 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,035,819 - 4,062,907 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prkcd
998 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2508
Count of miRNA genes:581
Interacting mature miRNAs:739
Transcripts:ENSMUST00000022521, ENSMUST00000112202, ENSMUST00000112203, ENSMUST00000112206, ENSMUST00000112207, ENSMUST00000112208, ENSMUST00000112210, ENSMUST00000112211, ENSMUST00000128135, ENSMUST00000130736, ENSMUST00000135714, ENSMUST00000140701, ENSMUST00000145806
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143032195748837457Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143032195752937457Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse

Markers in Region
AI385711  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381430,595,675 - 30,595,785UniSTSGRCm38
MGSCv371431,408,861 - 31,408,971UniSTSGRCm37
Celera1426,853,325 - 26,853,435UniSTS
Cytogenetic Map14BUniSTS
cM Map1411.0UniSTS
Whitehead/MRC_RH14227.12UniSTS
D14Ertd420e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381430,595,369 - 30,595,597UniSTSGRCm38
MGSCv371431,408,555 - 31,408,783UniSTSGRCm37
Celera1426,853,019 - 26,853,247UniSTS
Cytogenetic Map14BUniSTS
cM Map1410.5UniSTS
cM Map1411.0UniSTS
UniSTS:224276  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381430,595,534 - 30,595,723UniSTSGRCm38
MGSCv371431,408,720 - 31,408,909UniSTSGRCm37
Celera1426,853,184 - 26,853,373UniSTS
Cytogenetic Map14BUniSTS
cM Map1411.0UniSTS
D16Mgh7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381430,595,520 - 30,595,662UniSTSGRCm38
MGSCv371431,408,706 - 31,408,848UniSTSGRCm37
Celera1426,853,170 - 26,853,312UniSTS
Cytogenetic Map14BUniSTS
cM Map1411.0UniSTS
Prkcd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381430,595,705 - 30,595,897UniSTSGRCm38
MGSCv371431,408,891 - 31,409,083UniSTSGRCm37
Celera1426,853,355 - 26,853,547UniSTS
Cytogenetic Map14BUniSTS
cM Map1411.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001310682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA616214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB011812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB201453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB201454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB201455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB201456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF251036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF274044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI385711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW122017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY545076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY750197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF170573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU182370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ840432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M69042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000022521   ⟹   ENSMUSP00000022521
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,317,315 - 30,332,259 (-)Ensembl
GRCm38.p6 Ensembl1430,595,358 - 30,610,302 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112202   ⟹   ENSMUSP00000107821
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,320,364 - 30,329,779 (-)Ensembl
GRCm38.p6 Ensembl1430,598,407 - 30,607,822 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112203   ⟹   ENSMUSP00000107822
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,320,364 - 30,329,779 (-)Ensembl
GRCm38.p6 Ensembl1430,598,407 - 30,607,822 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112206   ⟹   ENSMUSP00000107825
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,317,551 - 30,329,779 (-)Ensembl
GRCm38.p6 Ensembl1430,595,594 - 30,607,822 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112207   ⟹   ENSMUSP00000107826
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,317,549 - 30,329,779 (-)Ensembl
GRCm38.p6 Ensembl1430,595,592 - 30,607,822 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112208
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,328,716 - 30,348,167 (-)Ensembl
GRCm38.p6 Ensembl1430,606,759 - 30,626,210 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112210   ⟹   ENSMUSP00000107829
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,317,311 - 30,348,167 (-)Ensembl
GRCm38.p6 Ensembl1430,595,354 - 30,626,210 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112211   ⟹   ENSMUSP00000107830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,317,313 - 30,348,165 (-)Ensembl
GRCm38.p6 Ensembl1430,595,356 - 30,626,208 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130736
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,322,219 - 30,348,129 (-)Ensembl
GRCm38.p6 Ensembl1430,600,262 - 30,626,172 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,324,367 - 30,329,302 (-)Ensembl
GRCm38.p6 Ensembl1430,602,410 - 30,607,345 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140701
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,317,610 - 30,322,164 (-)Ensembl
GRCm38.p6 Ensembl1430,595,653 - 30,600,207 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145806
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,324,476 - 30,327,628 (-)Ensembl
GRCm38.p6 Ensembl1430,602,519 - 30,605,671 (-)Ensembl
RefSeq Acc Id: ENSMUST00000227078
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1430,329,075 - 30,331,252 (-)Ensembl
GRCm38.p6 Ensembl1430,607,118 - 30,609,295 (-)Ensembl
RefSeq Acc Id: NM_001310682   ⟹   NP_001297611
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,317,311 - 30,332,267 (-)NCBI
GRCm381430,595,354 - 30,610,310 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001424500   ⟹   NP_001411429
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,317,311 - 30,347,430 (-)NCBI
RefSeq Acc Id: NM_011103   ⟹   NP_035233
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,317,311 - 30,348,167 (-)NCBI
GRCm381430,595,354 - 30,626,208 (-)NCBI
MGSCv371431,408,555 - 31,423,498 (-)RGD
Celera1426,853,004 - 26,883,875 (-)ENTREZGENE
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518695   ⟹   XP_006518758
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,317,310 - 30,348,371 (-)NCBI
GRCm381430,595,353 - 30,626,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518697   ⟹   XP_006518760
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,320,364 - 30,348,371 (-)NCBI
GRCm381430,598,407 - 30,626,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518698   ⟹   XP_006518761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,320,361 - 30,348,637 (-)NCBI
GRCm381430,598,404 - 30,626,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315918   ⟹   XP_017171407
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,317,310 - 30,347,761 (-)NCBI
GRCm381430,595,354 - 30,625,819 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001297611 (Get FASTA)   NCBI Sequence Viewer  
  NP_001411429 (Get FASTA)   NCBI Sequence Viewer  
  NP_035233 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518758 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518760 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518761 (Get FASTA)   NCBI Sequence Viewer  
  XP_017171407 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA73056 (Get FASTA)   NCBI Sequence Viewer  
  AAF64316 (Get FASTA)   NCBI Sequence Viewer  
  AAF79208 (Get FASTA)   NCBI Sequence Viewer  
  AAH51416 (Get FASTA)   NCBI Sequence Viewer  
  AAS57795 (Get FASTA)   NCBI Sequence Viewer  
  ADX77909 (Get FASTA)   NCBI Sequence Viewer  
  BAA36408 (Get FASTA)   NCBI Sequence Viewer  
  BAE25785 (Get FASTA)   NCBI Sequence Viewer  
  BAE36451 (Get FASTA)   NCBI Sequence Viewer  
  BAE40604 (Get FASTA)   NCBI Sequence Viewer  
  BAE93682 (Get FASTA)   NCBI Sequence Viewer  
  BAE93683 (Get FASTA)   NCBI Sequence Viewer  
  BAE93684 (Get FASTA)   NCBI Sequence Viewer  
  BAE93685 (Get FASTA)   NCBI Sequence Viewer  
  CAA42845 (Get FASTA)   NCBI Sequence Viewer  
  EDL24758 (Get FASTA)   NCBI Sequence Viewer  
  EDL24759 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000022521
  ENSMUSP00000022521.7
  ENSMUSP00000107821
  ENSMUSP00000107821.2
  ENSMUSP00000107822
  ENSMUSP00000107822.2
  ENSMUSP00000107825.2
  ENSMUSP00000107826.2
  ENSMUSP00000107829
  ENSMUSP00000107829.4
  ENSMUSP00000107830
  ENSMUSP00000107830.3
GenBank Protein P28867 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_035233   ⟸   NM_011103
- Peptide Label: isoform 2
- UniProtKB: Q91V85 (UniProtKB/Swiss-Prot),   Q9Z333 (UniProtKB/Swiss-Prot),   P28867 (UniProtKB/Swiss-Prot),   Q53YN4 (UniProtKB/TrEMBL),   Q3UNG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006518758   ⟸   XM_006518695
- Peptide Label: isoform X1
- UniProtKB: Q3UNG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006518761   ⟸   XM_006518698
- Peptide Label: isoform X4
- UniProtKB: Q3UNG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006518760   ⟸   XM_006518697
- Peptide Label: isoform X2
- UniProtKB: Q3UNG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017171407   ⟸   XM_017315918
- Peptide Label: isoform X1
- UniProtKB: Q3UNG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001297611   ⟸   NM_001310682
- Peptide Label: isoform 1
- UniProtKB: Q3UNG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000107821   ⟸   ENSMUST00000112202
RefSeq Acc Id: ENSMUSP00000107826   ⟸   ENSMUST00000112207
RefSeq Acc Id: ENSMUSP00000107822   ⟸   ENSMUST00000112203
RefSeq Acc Id: ENSMUSP00000107825   ⟸   ENSMUST00000112206
RefSeq Acc Id: ENSMUSP00000107830   ⟸   ENSMUST00000112211
RefSeq Acc Id: ENSMUSP00000107829   ⟸   ENSMUST00000112210
RefSeq Acc Id: ENSMUSP00000022521   ⟸   ENSMUST00000022521
RefSeq Acc Id: NP_001411429   ⟸   NM_001424500
- Peptide Label: isoform 2
- UniProtKB: Q9Z333 (UniProtKB/Swiss-Prot),   Q91V85 (UniProtKB/Swiss-Prot),   P28867 (UniProtKB/Swiss-Prot),   Q3UNG2 (UniProtKB/TrEMBL),   Q53YN4 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28867-F1-model_v2 AlphaFold P28867 1-674 view protein structure

Promoters
RGD ID:8681770
Promoter ID:EPDNEW_M18916
Type:initiation region
Name:Prkcd_2
Description:Mus musculus protein kinase C, delta , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18917  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381430,607,795 - 30,607,855EPDNEW
RGD ID:8681772
Promoter ID:EPDNEW_M18917
Type:initiation region
Name:Prkcd_1
Description:Mus musculus protein kinase C, delta , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18916  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381430,626,207 - 30,626,267EPDNEW
RGD ID:6825292
Promoter ID:MM_KWN:16054
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000061826
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361431,412,796 - 31,414,092 (-)MPROMDB
RGD ID:6825296
Promoter ID:MM_KWN:16055
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung
Transcripts:UC007SVL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361431,416,854 - 31,417,354 (-)MPROMDB
RGD ID:6825291
Promoter ID:MM_KWN:16056
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000061824,   OTTMUST00000061825
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361431,418,821 - 31,419,321 (-)MPROMDB
RGD ID:6825290
Promoter ID:MM_KWN:16057
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Lung,   Spleen
Transcripts:ENSMUST00000112202,   ENSMUST00000112203,   OTTMUST00000061823,   UC007SVD.1,   UC007SVE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361431,420,841 - 31,421,902 (-)MPROMDB
RGD ID:6825293
Promoter ID:MM_KWN:16058
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Lung,   Spleen
Transcripts:NM_011103,   UC007SVG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361431,423,041 - 31,424,497 (-)MPROMDB
RGD ID:6825295
Promoter ID:MM_KWN:16059
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000112204,   ENSMUST00000112208,   ENSMUST00000112210,   ENSMUST00000112211,   UC007SVK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361431,439,251 - 31,439,962 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97598 AgrOrtholog
Ensembl Genes ENSMUSG00000021948 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022521 ENTREZGENE
  ENSMUST00000022521.13 UniProtKB/Swiss-Prot
  ENSMUST00000112202 ENTREZGENE
  ENSMUST00000112202.8 UniProtKB/TrEMBL
  ENSMUST00000112203 ENTREZGENE
  ENSMUST00000112203.2 UniProtKB/TrEMBL
  ENSMUST00000112206.8 UniProtKB/TrEMBL
  ENSMUST00000112207.8 UniProtKB/TrEMBL
  ENSMUST00000112210 ENTREZGENE
  ENSMUST00000112210.11 UniProtKB/Swiss-Prot
  ENSMUST00000112211 ENTREZGENE
  ENSMUST00000112211.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKC_delta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kin_PKC_delta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18753 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97598 ENTREZGENE
NCBI Gene 18753 ENTREZGENE
PANTHER PROTEIN KINASE C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN KINASE C DELTA TYPE UniProtKB/TrEMBL
  RIBOSOMAL PROTEIN S6 KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKC_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prkcd PhenoGen
PIRSF PKC_delta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kin_C_delta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57889 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F1DGF6_MOUSE UniProtKB/TrEMBL
  KPCD_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q1MX40_MOUSE UniProtKB/TrEMBL
  Q1MX41_MOUSE UniProtKB/TrEMBL
  Q1MX42_MOUSE UniProtKB/TrEMBL
  Q1MX43_MOUSE UniProtKB/TrEMBL
  Q3TGE4_MOUSE UniProtKB/TrEMBL
  Q3TT74_MOUSE UniProtKB/TrEMBL
  Q3UNG2 ENTREZGENE, UniProtKB/TrEMBL
  Q53YN4 ENTREZGENE, UniProtKB/TrEMBL
  Q80UN7_MOUSE UniProtKB/TrEMBL
  Q91V85 ENTREZGENE
  Q9Z333 ENTREZGENE
UniProt Secondary Q91V85 UniProtKB/Swiss-Prot
  Q9Z333 UniProtKB/Swiss-Prot