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Gene: Casp3 (caspase 3) Mus musculus
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Symbol: Casp3
Name: caspase 3
Description: Exhibits aspartic-type endopeptidase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and cysteine-type endopeptidase activity involved in execution phase of apoptosis. Involved in several processes, including anterior neural tube closure; lymphocyte homeostasis; and negative regulation of lymphocyte proliferation. Localizes to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease; colon cancer; and lung non-small cell carcinoma. Is expressed in several structures, including branchial arch; gut; heart; nervous system; and respiratory system. Orthologous to human CASP3 (caspase 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A830040C14Rik; AC-3; Apopain; CASP-3; caspase 3, apoptosis related cysteine protease; caspase-3; CC3; CPP-32; CPP32; cysteine protease CPP32; Lice; mldy; SCA-1; SREBP cleavage activity 1; Yama
Orthologs:
Homo sapiens (human) : CASP3 (caspase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casp3 (caspase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp3 (caspase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP3 (caspase 3)
Canis lupus familiaris (dog) : CASP3 (caspase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp3 (caspase 3)
Sus scrofa (pig) : CASP3 (caspase 3)
Chlorocebus sabaeus (African green monkey) : CASP3 (caspase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl846,617,291 - 46,639,689 (+)EnsemblGRCm38mm10GRCm38
GRCm38846,617,291 - 46,639,698 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37847,702,803 - 47,724,071 (+)NCBIGRCm37mm9NCBIm37
MGSCv36848,116,266 - 48,137,534 (+)NCBImm8
Celera849,300,031 - 49,321,270 (+)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map826.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model