Casp3 (caspase 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Casp3 (caspase 3) Mus musculus
Analyze
Symbol: Casp3
Name: caspase 3
RGD ID: 10289
MGI Page MGI
Description: Enables aspartic-type endopeptidase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and cysteine-type endopeptidase activity involved in execution phase of apoptosis. Involved in intrinsic apoptotic signaling pathway in response to osmotic stress and positive regulation of apoptotic process. Acts upstream of or within several processes, including anterior neural tube closure; lymphocyte homeostasis; and negative regulation of lymphocyte proliferation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; gut; heart; limb; and respiratory system. Human ortholog(s) of this gene implicated in Parkinson's disease; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP3 (caspase 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A830040C14Rik; AC-; AC-3; Apopain; Casp; CASP-3; caspase 3, apoptosis related cysteine protease; caspase-3; CC3; CPP; CPP-32; CPP32; cysteine protease CPP32; Lice; mld; mldy; SCA-1; SREBP cleavage activity 1; Ya; Yama
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39847,070,326 - 47,092,733 (+)NCBIGRCm39mm39
GRCm39 Ensembl847,070,326 - 47,092,724 (+)Ensembl
GRCm38846,617,291 - 46,639,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl846,617,291 - 46,639,689 (+)EnsemblGRCm38mm10GRCm38
MGSCv37847,702,803 - 47,724,071 (+)NCBIGRCm37mm9NCBIm37
MGSCv36848,116,266 - 48,137,534 (+)NCBImm8
Celera849,300,031 - 49,321,270 (+)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map826.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model