Cxcl15 (chemokine (C-X-C motif) ligand 15)

Functional Annotation unavailable	Annotation Distribution unavailable	Genomic Variants unavailble for Mouse Genomic Variants unavailable
Functional Annotation	Annotation Distribution	Genomic Variants

Protein-Protein Interactions unavailable	Genome Viewer unavailable	Damaging Variants unavailble for Mouse Damaging Variants unavailable
Protein-Protein Interactions	Genome Viewer	Damaging Variants

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Annotation Comparison	OLGA	Excel (Download)

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Gene: Cxcl15 (chemokine (C-X-C motif) ligand 15) Mus musculus

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General
Array IDs
References

Symbol:

Cxcl15

Name:

chemokine (C-X-C motif) ligand 15

Description:

null

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

C-X-C motif chemokine 15; Il8; interleukin 8; lungkine; Scyb15; small inducible cytokine subfamily B, member 15; small-inducible cytokine B15; weche

Orthologs:

Homo sapiens (human) : CXCL8 (C-X-C motif chemokine ligand 8) HGNC Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcl8 (C-X-C motif chemokine ligand 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL8 (C-X-C motif chemokine ligand 8)
Canis lupus familiaris (dog) : CXCL8 (C-X-C motif chemokine ligand 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcl8 (C-X-C motif chemokine ligand 8)
Sus scrofa (pig) : CXCL8 (C-X-C motif chemokine ligand 8)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CXCL8 (C-X-C motif chemokine ligand 8)	HGNC	Treefam
Chinchilla lanigera (long-tailed chinchilla):	Cxcl8 (C-X-C motif chemokine ligand 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CXCL8 (C-X-C motif chemokine ligand 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CXCL8 (C-X-C motif chemokine ligand 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cxcl8 (C-X-C motif chemokine ligand 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CXCL8 (C-X-C motif chemokine ligand 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CXCL2 (C-X-C motif chemokine ligand 2)	HGNC	Treefam
Homo sapiens (human):	PF4 (platelet factor 4)	HGNC	Treefam
Homo sapiens (human):	PPBP (pro-platelet basic protein)	HGNC	Treefam
Homo sapiens (human):	CXCL1 (C-X-C motif chemokine ligand 1)	HGNC	Treefam
Homo sapiens (human):	CXCL6 (C-X-C motif chemokine ligand 6)	HGNC	Treefam
Homo sapiens (human):	CXCL5 (C-X-C motif chemokine ligand 5)	HGNC	Treefam
Homo sapiens (human):	CXCL3 (C-X-C motif chemokine ligand 3)	HGNC	Treefam
Homo sapiens (human):	PF4V1 (platelet factor 4 variant 1)	HGNC	Treefam
Alliance orthologs ³
Homo sapiens (human):	CXCL8 (C-X-C motif chemokine ligand 8)	Alliance	DIOPT (Ensembl Compara, TreeFam)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm38	5	90,794,534 - 90,803,067 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
MGSCv37	5	91,223,560 - 91,232,093 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	5	91,869,771 - 91,877,088 (+)	NCBI			mm8
Celera	5	88,946,158 - 88,954,669 (+)	NCBI		Celera
Cytogenetic Map	5	E1	NCBI
cM Map	5	44.78	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

Disease Annotations

Imported Annotations - CTD

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
adenocarcinoma		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18307536
alcoholic hepatitis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:26220752
allergic hypersensitivity disease		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:21625544
Bacterial Eye Infections		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:23661603
Barrett's esophagus		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:15387324
Behcet's disease		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:8712863
Breast Neoplasms		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:16298037, PMID:17516992
bullous pemphigoid		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:11359455
bullous pemphigoid		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:11359455
Cachexia		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:17878525
Cardiotoxicity		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:29959987
Cell Transformation, Neoplastic		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:22015448
cholestasis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:21224055
chronic obstructive pulmonary disease		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:15337792 more ...
Colorectal Neoplasms		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:20065508
congestive heart failure		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:29959987
cutaneous leishmaniasis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:20102417
Down syndrome		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:16289943
Edema		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19874808
Endometrial Neoplasms		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:17380299
fatty liver disease		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:23348005
Fever		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:11852909
gastroesophageal reflux disease		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18193101, PMID:20616304
glioblastoma multiforme		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:16356833
glomerulonephritis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:9403216, PMID:10910440
hepatocellular carcinoma		ISO	RGD:1345686	11554173	CTD Direct Evidence: therapeutic	CTD	PMID:12432545
Hyperalgesia		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:7881729, PMID:10401557
Inflammation		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:20578705, PMID:24795235
intermediate coronary syndrome		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:10660968
Intractable Pain		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:11280320
keratitis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:23661603
lichen disease		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18393961
liver cirrhosis		EXP		11554173	CTD Direct Evidence: therapeutic	CTD	PMID:15763341
lung non-small cell carcinoma		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:15956251
malignant mesothelioma		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:25162674
oral submucous fibrosis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28984080
Ovarian Neoplasms		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19401270, PMID:21742513
pancreatic cancer		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18307536
peptic esophagitis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18193101
Pneumococcal Pneumonia		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:24894820
pneumonia		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:21625544
Postherpetic Neuralgia		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:11280320
Prostatic Neoplasms		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:16606632, PMID:17606477
psoriatic arthritis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19732956
pulmonary fibrosis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:17266442, PMID:17894541
pulmonary hypertension		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:15302794
Reperfusion Injury		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:12865660
rheumatoid arthritis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:17379860, PMID:19192274
Salmonella Infections, Animal		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:29421334
squamous cell carcinoma		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:15956251
Staphylococcal Infections		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:23661603
Stomach Neoplasms		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism, therapeutic	CTD	PMID:15492468, PMID:15723263
Thyroid Neoplasms		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:26037280
Tobacco Use Disorder		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28864214
ulcerative colitis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:12133438, PMID:15955209
urinary bladder cancer		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:22015448
visceral leishmaniasis		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:22461696
Wilson disease		ISO	RGD:1345686	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:25002079

Gene-Chemical Interaction Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
(+)-alpha-tocopherol	multiple interactions	ISO	RGD:1345686	6480464	[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein] more ...	CTD	PMID:19135038, PMID:25551565
(+)-catechin	multiple interactions	ISO	RGD:1345686	6480464	[Catechin co-treated with tert-Butylhydroperoxide co-treated with Hydrocortisone] results in decreased secretion of CXCL8 protein	CTD	PMID:29935159
(-)-anisomycin	decreases expression	ISO	RGD:1345686	6480464	Anisomycin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
(-)-anisomycin	increases expression	ISO	RGD:1345686	6480464	Anisomycin results in increased expression of CXCL8 mRNA	CTD	PMID:22003189
(-)-anisomycin	multiple interactions	ISO	RGD:1345686	6480464	[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [Anisomycin results in increased expression of CXCL8 mRNA]	CTD	PMID:22003189
(-)-demecolcine	increases expression	ISO	RGD:1345686	6480464	Demecolcine results in increased expression of CXCL8 mRNA	CTD	PMID:23649840
(-)-epigallocatechin 3-gallate	multiple interactions	ISO	RGD:1345686	6480464	epigallocatechin gallate inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased expression of and results in increased secretion of CXCL8 protein], epigallocatechin gallate inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]	CTD	PMID:18377686, PMID:18413660
(-)-epigallocatechin 3-gallate	decreases secretion	ISO	RGD:1345686	6480464	epigallocatechin gallate results in decreased secretion of CXCL8 protein	CTD	PMID:20816778
(-)-selegiline	multiple interactions	ISO	RGD:1345686	6480464	Selegiline inhibits the reaction [Smoke analog results in increased secretion of CXCL8 protein]	CTD	PMID:28108387
(2-trans,6-trans)-farnesol	increases expression	ISO	RGD:1345686	6480464	Farnesol results in increased expression of CXCL8 mRNA	CTD	PMID:27965148, PMID:30806763
(2-trans,6-trans)-farnesol	increases secretion	ISO	RGD:1345686	6480464	Farnesol results in increased secretion of CXCL8 protein	CTD	PMID:30806763
(24S)-24-hydroxycholesterol	increases expression	ISO	RGD:1345686	6480464	24-hydroxycholesterol results in increased expression of CXCL8 mRNA	CTD	PMID:24802026
(24S)-24-hydroxycholesterol	multiple interactions	ISO	RGD:1345686	6480464	[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta more ...	CTD	PMID:24802026
(25R)-cholest-5-ene-3beta,26-diol	multiple interactions	ISO	RGD:1345686	6480464	[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta more ...	CTD	PMID:24802026
(25R)-cholest-5-ene-3beta,26-diol	increases expression	ISO	RGD:1345686	6480464	27-hydroxycholesterol results in increased expression of CXCL8 mRNA	CTD	PMID:19426978, PMID:24802026
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid	multiple interactions	ISO	RGD:1345686	6480464	zopolrestat inhibits the reaction [Antigens, Plant results in increased secretion of CXCL8 protein]	CTD	PMID:21334316
(E)-cinnamyl alcohol	increases expression	ISO	RGD:1345686	6480464	cinnamyl alcohol results in increased expression of CXCL8 mRNA, cinnamyl alcohol results in increased expression of CXCL8 protein	CTD	PMID:21920952 more ...
(E)-roxithromycin	multiple interactions	ISO	RGD:1345686	6480464	Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of CXCL8 mRNA], Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of CXCL8 protein]	CTD	PMID:17524151
(R)-mevalonic acid	multiple interactions	ISO	RGD:1345686	6480464	Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]] more ...	CTD	PMID:12117737, PMID:16511915
(R)-noradrenaline	multiple interactions	ISO	RGD:1345686	6480464	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Norepinephrine results in increased secretion of CXCL8 protein], Prazosin inhibits the reaction [Norepinephrine results in increased secretion of CXCL8 protein]	CTD	PMID:16782692
(R)-pantothenic acid	increases expression	ISO	RGD:1345686	6480464	Pantothenic Acid results in increased expression of CXCL8 mRNA	CTD	PMID:19397697
(S)-colchicine	multiple interactions	ISO	RGD:1345686	6480464	[Colchicine co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
(S)-colchicine	increases expression	ISO	RGD:1345686	6480464	Colchicine results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
(S)-naringenin	multiple interactions	ISO	RGD:1345686	6480464	naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CXCL8 protein]	CTD	PMID:19135038
(S)-nicotine	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:22119045, PMID:23199342
(S)-nicotine	increases expression	ISO	RGD:1345686	6480464	Nicotine results in increased expression of CXCL8 mRNA	CTD	PMID:22119045
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane	multiple interactions	ISO	RGD:1345686	6480464	2 more ...	CTD	PMID:30017638
1,10-phenanthroline	increases expression	ISO	RGD:1345686	6480464	1, 10-phenanthroline results in increased expression of CXCL8 mRNA	CTD	PMID:19641517
1,2,3-Trichloropropane	increases expression	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:22952646
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine	multiple interactions	ISO	RGD:1345686	6480464	1, 2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]	CTD	PMID:19041333
1,2-dipalmitoylphosphatidylcholine	multiple interactions	ISO	RGD:1345686	6480464	1, 2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]	CTD	PMID:19041333
1,2-Naphthoquinone	multiple interactions	ISO	RGD:1345686	6480464	CAT protein inhibits the reaction [1, 2-naphthoquinone results in increased expression of CXCL8 mRNA]	CTD	PMID:21997482
1,2-Naphthoquinone	increases expression	ISO	RGD:1345686	6480464	1, 2-naphthoquinone results in increased expression of CXCL8 mRNA	CTD	PMID:21997482, PMID:23724284
1,3-benzothiazole-2-thiol	multiple interactions	ISO	RGD:1345686	6480464	[captax co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
1,3-benzothiazole-2-thiol	increases expression	ISO	RGD:1345686	6480464	captax results in increased expression of CXCL8 mRNA, captax results in increased expression of CXCL8 protein	CTD	PMID:20713136 more ...
1,4-benzoquinone	increases expression	ISO	RGD:1345686	6480464	quinone results in increased expression of CXCL8 mRNA, quinone results in increased expression of CXCL8 protein	CTD	PMID:17572062, PMID:23724284
1,4-benzoquinone	increases secretion	ISO	RGD:1345686	6480464	quinone results in increased secretion of CXCL8 protein	CTD	PMID:20541004
1,4-naphthoquinone	increases expression	ISO	RGD:1345686	6480464	1, 4-naphthoquinone results in increased expression of CXCL8 mRNA	CTD	PMID:23333790
1,4-phenylenediamine	multiple interactions	ISO	RGD:1345686	6480464	bisindolylmaleimide I affects the reaction [4-phenylenediamine results in increased expression of CXCL8 protein], SB 203580 affects the reaction [4-phenylenediamine results in increased secretion of CXCL8 protein]	CTD	PMID:18494145, PMID:24136171
1,4-phenylenediamine	increases secretion	ISO	RGD:1345686	6480464	4-phenylenediamine results in increased secretion of CXCL8 protein	CTD	PMID:16099135, PMID:18494145
1,4-phenylenediamine	increases expression	ISO	RGD:1345686	6480464	4-phenylenediamine results in increased expression of CXCL8 mRNA, 4-phenylenediamine results in increased expression of CXCL8 protein	CTD	PMID:20491607 more ...
1-chloro-2,4-dinitrobenzene	multiple interactions	ISO	RGD:1345686	6480464	[Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of CXCL8 protein more ...	CTD	PMID:18494145 more ...
1-chloro-2,4-dinitrobenzene	increases secretion	ISO	RGD:1345686	6480464	Dinitrochlorobenzene results in increased secretion of CXCL8 protein	CTD	PMID:12781210 more ...
1-chloro-2,4-dinitrobenzene	increases expression	ISO	RGD:1345686	6480464	Dinitrochlorobenzene results in increased expression of CXCL8 mRNA, Dinitrochlorobenzene results in increased expression of CXCL8 protein	CTD	PMID:12781210 more ...
1-chloro-2,4-dinitrobenzene	increases stability	ISO	RGD:1345686	6480464	Dinitrochlorobenzene results in increased stability of CXCL8 mRNA	CTD	PMID:21969073
1-fluoro-2,4-dinitrobenzene	multiple interactions	ISO	RGD:1345686	6480464	BIRB 796 inhibits the reaction [Dinitrofluorobenzene results in increased secretion of CXCL8 protein]	CTD	PMID:19427879
1-fluoro-2,4-dinitrobenzene	increases expression	ISO	RGD:1345686	6480464	Dinitrofluorobenzene results in increased expression of CXCL8 mRNA	CTD	PMID:12781210, PMID:25091725
1-fluoro-2,4-dinitrobenzene	increases secretion	ISO	RGD:1345686	6480464	Dinitrofluorobenzene results in increased secretion of CXCL8 protein	CTD	PMID:12781210, PMID:19427879
1-nitronaphthalene	decreases expression	ISO	RGD:1345686	6480464	1-nitronaphthalene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
1-nitropyrene	decreases expression	ISO	RGD:1345686	6480464	1-nitropyrene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
1-nitropyrene	increases secretion	ISO	RGD:1345686	6480464	1-nitropyrene results in increased secretion of CXCL8 protein	CTD	PMID:19428942 more ...
1-nitropyrene	increases expression	ISO	RGD:1345686	6480464	1-nitropyrene results in increased expression of CXCL8 mRNA	CTD	PMID:12393170 more ...
1-nitropyrene	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:12393170 more ...
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine	increases expression	ISO	RGD:1345686	6480464	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of CXCL8 mRNA	CTD	PMID:16386258
14-Deoxy-11,12-didehydroandrographolide	multiple interactions	ISO	RGD:1345686	6480464	14-deoxy-11, 12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]	CTD	PMID:27089844
15-deoxy-Delta(12,14)-prostaglandin J2	multiple interactions	ISO	RGD:1345686	6480464	15-deoxy-delta(12 more ...	CTD	PMID:14998300 more ...
15-deoxy-Delta(12,14)-prostaglandin J2	increases expression	ISO	RGD:1345686	6480464	15-deoxy-delta(12, 14)-prostaglandin J2 results in increased expression of CXCL8 protein	CTD	PMID:20174873
17beta-estradiol	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:12574206 more ...
17beta-estradiol	increases expression	ISO	RGD:1345686	6480464	Estradiol results in increased expression of CXCL8 mRNA	CTD	PMID:19401270 more ...
17beta-estradiol	decreases expression	ISO	RGD:1345686	6480464	Estradiol results in decreased expression of CXCL8 mRNA	CTD	PMID:16298037 more ...
17beta-estradiol	increases expression	EXP		6480464	Estradiol results in increased expression of CXCL15 mRNA	CTD	PMID:19484750
17beta-estradiol	affects expression	ISO	RGD:1345686	6480464	Estradiol affects the expression of CXCL8 mRNA	CTD	PMID:14699072, PMID:22574217
17beta-estradiol	increases secretion	ISO	RGD:1345686	6480464	Estradiol results in increased secretion of CXCL8 protein	CTD	PMID:19401270
17beta-estradiol	decreases secretion	ISO	RGD:1345686	6480464	Estradiol results in decreased secretion of CXCL8 protein	CTD	PMID:16517565
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one	multiple interactions	ISO	RGD:1345686	6480464	AR mRNA affects the reaction [Metribolone results in increased secretion of CXCL8 protein] more ...	CTD	PMID:20711410
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one	increases secretion	ISO	RGD:1345686	6480464	Metribolone results in increased secretion of CXCL8 protein	CTD	PMID:20711410
17beta-hydroxy-5alpha-androstan-3-one	multiple interactions	ISO	RGD:1345686	6480464	[Lipopolysaccharides co-treated with Dihydrotestosterone] results in increased secretion of CXCL8 protein	CTD	PMID:27239218
2,2',4,4',5,5'-hexachlorobiphenyl	decreases secretion	ISO	RGD:1345686	6480464	2 more ...	CTD	PMID:25433332
2,2',4,4',5,5'-hexachlorobiphenyl	multiple interactions	ISO	RGD:1345686	6480464	fulvestrant inhibits the reaction [2 more ...	CTD	PMID:25433332
2,2',4,4'-Tetrabromodiphenyl ether	multiple interactions	ISO	RGD:1345686	6480464	2 more ...	CTD	PMID:24296301
2,2',4,4'-Tetrabromodiphenyl ether	increases expression	ISO	RGD:1345686	6480464	2 more ...	CTD	PMID:24296301
2,2',4,4'-Tetrabromodiphenyl ether	decreases secretion	ISO	RGD:1345686	6480464	2 more ...	CTD	PMID:19211157
2,2'-bipyridine	multiple interactions	ISO	RGD:1345686	6480464	2, 2'-Dipyridyl inhibits the reaction [sodium arsenite results in increased expression of CXCL8 mRNA]	CTD	PMID:24570342
2,2,2-tetramine	multiple interactions	ISO	RGD:1345686	6480464	[Trientine results in decreased activity of Copper] which results in decreased expression of CXCL8 more ...	CTD	PMID:12432545
2,2,2-tetramine	decreases expression	ISO	RGD:1345686	6480464	Trientine results in decreased expression of CXCL8 mRNA, Trientine results in decreased expression of CXCL8 protein	CTD	PMID:12432545
2,3,3',4,4',5,5'-Heptachlorobiphenyl	affects expression	ISO	RGD:1345686	6480464	2 more ...	CTD	PMID:22326254
2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1345686	6480464	Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA	CTD	PMID:12377990 more ...
2,3,7,8-tetrachlorodibenzodioxine	increases secretion	ISO	RGD:1345686	6480464	Tetrachlorodibenzodioxin results in increased secretion of CXCL8 protein	CTD	PMID:16517565 more ...
2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of CXCL15 mRNA	CTD	PMID:21570461
2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA	CTD	PMID:19063610
2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	EXP		6480464	Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA] more ...	CTD	PMID:19063610
2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:1345686	6480464	Tetrachlorodibenzodioxin results in decreased expression of CXCL8 mRNA	CTD	PMID:17101203, PMID:19147701
2,3,7,8-tetrachlorodibenzodioxine	decreases secretion	ISO	RGD:1345686	6480464	Tetrachlorodibenzodioxin results in decreased secretion of CXCL8 protein	CTD	PMID:16517565
2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	RGD:1345686	6480464	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:16517565 more ...
2,4,6-trinitrobenzenesulfonic acid	multiple interactions	ISO	RGD:1345686	6480464	Betamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA], Tacrolimus inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA]	CTD	PMID:20090409
2,4,6-trinitrobenzenesulfonic acid	increases secretion	ISO	RGD:1345686	6480464	Trinitrobenzenesulfonic Acid results in increased secretion of CXCL8 protein	CTD	PMID:12781210
2,4,6-trinitrobenzenesulfonic acid	increases expression	ISO	RGD:1345686	6480464	Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA, Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 protein	CTD	PMID:12781210 more ...
2,4-di-tert-butylphenol	increases expression	ISO	RGD:1345686	6480464	2, 4-di-tert-butylphenol results in increased expression of CXCL8 mRNA	CTD	PMID:30945539
2,4-di-tert-butylphenol	multiple interactions	ISO	RGD:1345686	6480464	2-(1 more ...	CTD	PMID:30945539
2,4-diaminotoluene	multiple interactions	ISO	RGD:1345686	6480464	[2, 4-diaminotoluene co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
2,4-dinitroiodobenzene	increases secretion	ISO	RGD:1345686	6480464	1-iodo-2, 4-dinitrobenzene results in increased secretion of CXCL8 protein	CTD	PMID:19427879
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione	decreases activity	ISO	RGD:1345686	6480464	Thalidomide results in decreased activity of CXCL8 protein	CTD	PMID:17557286
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione	multiple interactions	ISO	RGD:1345686	6480464	Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA], Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]	CTD	PMID:15687330
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine	multiple interactions	ISO	RGD:1345686	6480464	Foropafant inhibits the reaction [Platelet Activating Factor results in increased secretion of CXCL8 protein]	CTD	PMID:15149885
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine	increases secretion	ISO	RGD:1345686	6480464	Platelet Activating Factor results in increased secretion of CXCL8 protein	CTD	PMID:15149885
2-amino-2-deoxy-D-glucopyranose	multiple interactions	ISO	RGD:1345686	6480464	Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18026701 more ...
2-aminophenol	increases expression	ISO	RGD:1345686	6480464	2-aminophenol results in increased expression of CXCL8 mRNA	CTD	PMID:20491607
2-aminophenol	increases secretion	ISO	RGD:1345686	6480464	2-aminophenol results in increased secretion of CXCL8 protein	CTD	PMID:20541004
2-aminopurine	multiple interactions	ISO	RGD:1345686	6480464	2-Aminopurine inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA], 2-Aminopurine inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]	CTD	PMID:18599499
2-arachidonoylglycerol	multiple interactions	ISO	RGD:1345686	6480464	[SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein], CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]	CTD	PMID:15115777
2-arachidonoylglycerol	increases expression	ISO	RGD:1345686	6480464	glyceryl 2-arachidonate analog results in increased expression of CXCL8 protein, glyceryl 2-arachidonate results in increased expression of CXCL8 protein	CTD	PMID:15115777
2-bromo-2-(bromomethyl)pentanedinitrile	increases expression	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:21920952, PMID:27965148
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one	multiple interactions	ISO	RGD:1345686	6480464	Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]	CTD	PMID:23688403
2-Ethylhexyl acrylate	increases expression	ISO	RGD:1345686	6480464	2-ethylhexyl acrylate results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID	multiple interactions	ISO	RGD:1345686	6480464	[Sulfasalazine co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:12135912 more ...
2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID	decreases expression	ISO	RGD:1345686	6480464	Sulfasalazine results in decreased expression of CXCL8 mRNA	CTD	PMID:12133438 more ...
2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID	affects secretion	ISO	RGD:1345686	6480464	Sulfasalazine affects the secretion of CXCL8 protein	CTD	PMID:12231210
2-hydroxypropyl methacrylate	increases expression	ISO	RGD:1345686	6480464	2-hydroxypropyl methacrylate results in increased expression of CXCL8 mRNA	CTD	PMID:21920952
2-methylcholine	affects expression	ISO	RGD:1345686	6480464	beta-methylcholine affects the expression of CXCL8 mRNA	CTD	PMID:21179406
2-methylserotonin	multiple interactions	ISO	RGD:1345686	6480464	2-methyl-5-HT promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]	CTD	PMID:15802305
2-nitrofluorene	decreases expression	ISO	RGD:1345686	6480464	2-nitrofluorene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
2-nitronaphthalene	decreases expression	ISO	RGD:1345686	6480464	2-nitronaphthalene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
2-tert-butylhydroquinone	increases expression	ISO	RGD:1345686	6480464	2-tert-butylhydroquinone results in increased expression of CXCL8 mRNA	CTD	PMID:30806763
2-trans,6-trans,10-trans-geranylgeranyl diphosphate	multiple interactions	ISO	RGD:1345686	6480464	geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]	CTD	PMID:16511915
24,25-Dihydroxyvitamin D	decreases expression	ISO	RGD:1345686	6480464	24, 25-Dihydroxyvitamin D 3 results in decreased expression of CXCL8 protein	CTD	PMID:18379402
25-hydroxycholesterol	increases secretion	ISO	RGD:1345686	6480464	25-hydroxycholesterol results in increased secretion of CXCL8 protein	CTD	PMID:16142584
25-hydroxycholesterol	increases expression	ISO	RGD:1345686	6480464	25-hydroxycholesterol results in increased expression of CXCL8 mRNA	CTD	PMID:16142584, PMID:19426978
26-hydroxycholesterol	multiple interactions	ISO	RGD:1345686	6480464	[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta more ...	CTD	PMID:24802026
26-hydroxycholesterol	increases expression	ISO	RGD:1345686	6480464	27-hydroxycholesterol results in increased expression of CXCL8 mRNA	CTD	PMID:19426978, PMID:24802026
3',5'-cyclic AMP	multiple interactions	ISO	RGD:1345686	6480464	[Terbutaline results in increased abundance of Cyclic AMP] which results in increased expression of CXCL8 protein	CTD	PMID:9258252
3,3',4',5-tetrachlorosalicylanilide	increases expression	ISO	RGD:1345686	6480464	3 more ...	CTD	PMID:27965148
3,3',4,4',5-pentachlorobiphenyl	multiple interactions	ISO	RGD:1345686	6480464	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3 more ...	CTD	PMID:22262711 more ...
3,3',4,4',5-pentachlorobiphenyl	decreases expression	ISO	RGD:1345686	6480464	3 more ...	CTD	PMID:25433332
3,3',4,4',5-pentachlorobiphenyl	decreases secretion	ISO	RGD:1345686	6480464	3 more ...	CTD	PMID:25433332
3,3',4,4',5-pentachlorobiphenyl	increases expression	ISO	RGD:1345686	6480464	3 more ...	CTD	PMID:22262711, PMID:28351761
3,3',4,4',5-pentachlorobiphenyl	increases secretion	ISO	RGD:1345686	6480464	3 more ...	CTD	PMID:22262711 more ...
3,3',5,5'-tetrabromobisphenol A	decreases expression	ISO	RGD:1345686	6480464	tetrabromobisphenol A results in decreased expression of CXCL8 protein	CTD	PMID:26718265
3,3',5,5'-tetrabromobisphenol A	increases secretion	ISO	RGD:1345686	6480464	tetrabromobisphenol A results in increased secretion of CXCL8 protein	CTD	PMID:25461914
3,3',5,5'-tetrabromobisphenol A	increases expression	ISO	RGD:1345686	6480464	tetrabromobisphenol A results in increased expression of CXCL8 mRNA	CTD	PMID:25461914
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid	multiple interactions	ISO	RGD:1345686	6480464	MK-886 inhibits the reaction [Histamine results in increased expression of CXCL8 mRNA], MK-886 inhibits the reaction [Histamine results in increased expression of CXCL8 protein]	CTD	PMID:9609743
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione	multiple interactions	ISO	RGD:1345686	6480464	bisindolylmaleimide I affects the reaction [4-phenylenediamine results in increased expression of CXCL8 protein] more ...	CTD	PMID:17000667 more ...
3-aminophenol	increases expression	ISO	RGD:1345686	6480464	3-aminophenol results in increased expression of CXCL8 mRNA	CTD	PMID:20713136
3-isobutyl-1-methyl-7H-xanthine	multiple interactions	ISO	RGD:1345686	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CXCL8 mRNA	CTD	PMID:28628672
3-methyladenine	multiple interactions	ISO	RGD:1345686	6480464	3-methyladenine inhibits the reaction [Particulate Matter results in increased expression of CXCL8 mRNA], 3-methyladenine inhibits the reaction [Particulate Matter results in increased expression of CXCL8 protein]	CTD	PMID:28867211
3-Nitrofluoranthene	increases secretion	ISO	RGD:1345686	6480464	3-nitrofluoranthene results in increased secretion of CXCL8 protein	CTD	PMID:19879285
3-Nitrofluoranthene	increases expression	ISO	RGD:1345686	6480464	3-nitrofluoranthene results in increased expression of CXCL8 mRNA	CTD	PMID:19879285
4'-hydroxydiclofenac	increases expression	ISO	RGD:1345686	6480464	4'-hydroxydiclofenac results in increased expression of CXCL8 mRNA	CTD	PMID:24104198
4,4'-sulfonyldiphenol	increases expression	ISO	RGD:1345686	6480464	bis(4-hydroxyphenyl)sulfone results in increased expression of CXCL8 mRNA	CTD	PMID:30292839
4-(ethoxymethylene)-2-phenyloxazol-5-one	decreases expression	ISO	RGD:1345686	6480464	Oxazolone results in decreased expression of CXCL8 protein	CTD	PMID:8006454
4-(ethoxymethylene)-2-phenyloxazol-5-one	increases secretion	ISO	RGD:1345686	6480464	Oxazolone results in increased secretion of CXCL8 protein	CTD	PMID:12781210, PMID:17763283
4-(ethoxymethylene)-2-phenyloxazol-5-one	increases expression	ISO	RGD:1345686	6480464	Oxazolone results in increased expression of CXCL8 mRNA	CTD	PMID:12781210, PMID:27965148
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one	decreases expression	ISO	RGD:1345686	6480464	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CXCL8 protein	CTD	PMID:15762874
4-methoxyacetophenone	increases expression	ISO	RGD:1345686	6480464	4-acetylanisole results in increased expression of CXCL8 mRNA	CTD	PMID:21920952
4-nitroaniline	multiple interactions	ISO	RGD:1345686	6480464	[4-nitroaniline co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
4-nitrobenzyl bromide	increases expression	ISO	RGD:1345686	6480464	4-nitrobenzyl bromide results in increased expression of CXCL8 mRNA	CTD	PMID:21920952
4-nitrophenol	increases expression	ISO	RGD:1345686	6480464	4-nitrophenol results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
4-phenylbutyric acid	multiple interactions	ISO	RGD:1345686	6480464	4-phenylbutyric acid inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA], [4-phenylbutyric acid co-treated with N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide] results in decreased expression of CXCL8 protein	CTD	PMID:17709599
4-phenylbutyric acid	decreases expression	ISO	RGD:1345686	6480464	4-phenylbutyric acid results in decreased expression of CXCL8 protein	CTD	PMID:17709599
5-chloro-7-iodoquinolin-8-ol	increases expression	ISO	RGD:1345686	6480464	Clioquinol results in increased expression of CXCL8 mRNA	CTD	PMID:29966605
5-chloro-7-iodoquinolin-8-ol	increases secretion	ISO	RGD:1345686	6480464	Clioquinol results in increased secretion of CXCL8 protein	CTD	PMID:29966605
5-chloro-7-iodoquinolin-8-ol	multiple interactions	ISO	RGD:1345686	6480464	Clioquinol inhibits the reaction [GATA3 protein binds to CXCL8 promoter] more ...	CTD	PMID:29966605
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide	multiple interactions	ISO	RGD:1345686	6480464	Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CXCL8 mRNA]	CTD	PMID:27542212
5-fluorouracil	affects expression	ISO	RGD:1345686	6480464	Fluorouracil affects the expression of CXCL8 mRNA	CTD	PMID:16584549
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide	multiple interactions	ISO	RGD:1345686	6480464	(+)-JQ1 compound inhibits the reaction [6-chloro-2 more ...	CTD	PMID:26212199
6-Nitrochrysene	decreases expression	ISO	RGD:1345686	6480464	6-nitrochrysene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
6alpha-methylprednisolone	multiple interactions	ISO	RGD:1345686	6480464	[Methylprednisolone co-treated with Lidocaine] results in decreased expression of CXCL8 protein	CTD	PMID:11280320
6alpha-methylprednisolone	decreases expression	ISO	RGD:1345686	6480464	Methylprednisolone results in decreased expression of CXCL8 mRNA, Methylprednisolone results in decreased expression of CXCL8 protein	CTD	PMID:19192274
7-ketocholesterol	increases secretion	ISO	RGD:1345686	6480464	7-ketocholesterol results in increased secretion of CXCL8 protein	CTD	PMID:23454145
7-ketocholesterol	multiple interactions	ISO	RGD:1345686	6480464	resveratrol inhibits the reaction [7-ketocholesterol results in increased expression of CXCL8 protein]	CTD	PMID:24895526
7-ketocholesterol	increases expression	ISO	RGD:1345686	6480464	7-ketocholesterol results in increased expression of CXCL8 protein	CTD	PMID:24895526
7alpha-hydroxycholesterol	multiple interactions	ISO	RGD:1345686	6480464	[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta more ...	CTD	PMID:24802026
7alpha-hydroxycholesterol	increases secretion	ISO	RGD:1345686	6480464	cholest-5-en-3 beta, 7 alpha-diol results in increased secretion of CXCL8 protein	CTD	PMID:16142584
7alpha-hydroxycholesterol	increases expression	ISO	RGD:1345686	6480464	cholest-5-en-3 beta, 7 alpha-diol results in increased expression of CXCL8 mRNA	CTD	PMID:16142584, PMID:24802026
8-bromo-3',5'-cyclic AMP	multiple interactions	ISO	RGD:1345686	6480464	daidzein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:21056929
8-bromo-3',5'-cyclic AMP	increases expression	ISO	RGD:1345686	6480464	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA	CTD	PMID:21056929, PMID:22079614
8-OH-DPAT	multiple interactions	ISO	RGD:1345686	6480464	8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]	CTD	PMID:15802305
9,10-phenanthroquinone	increases expression	ISO	RGD:1345686	6480464	9, 10-phenanthrenequinone results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
AACOCF3	multiple interactions	ISO	RGD:1345686	6480464	arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA]	CTD	PMID:18938131, PMID:19162293
AACOCF3	multiple interactions	EXP		6480464	arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA]	CTD	PMID:19063610
abietic acid	increases expression	ISO	RGD:1345686	6480464	abietic acid results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
acenaphthene	decreases expression	ISO	RGD:1345686	6480464	acenaphthene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
acenaphthylene	decreases expression	ISO	RGD:1345686	6480464	acenaphthylene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
acetaldehyde	multiple interactions	ISO	RGD:1345686	6480464	Acetaldehyde results in increased expression of and results in increased secretion of CXCL8 protein more ...	CTD	PMID:15698409
acetaldehyde	increases expression	ISO	RGD:1345686	6480464	Acetaldehyde results in increased expression of CXCL8 mRNA, Acetaldehyde results in increased expression of CXCL8 protein	CTD	PMID:11344824, PMID:23416264
acetate ester	multiple interactions	ISO	RGD:1345686	6480464	[Butyrates results in increased acylation of Hyaluronic Acid metabolite] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of CXCL8 protein], [Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of CXCL8 protein	CTD	PMID:25053413
acetic anhydride	multiple interactions	ISO	RGD:1345686	6480464	[acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of CXCL8 protein	CTD	PMID:25053413
acetoacetic acid	increases secretion	ISO	RGD:1345686	6480464	acetoacetic acid results in increased secretion of CXCL8 protein	CTD	PMID:17665966
acetylleucyl-leucyl-norleucinal	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [acetylleucyl-leucyl-norleucinal results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12208513
acetylleucyl-leucyl-norleucinal	increases expression	ISO	RGD:1345686	6480464	acetylleucyl-leucyl-norleucinal results in increased expression of CXCL8 mRNA	CTD	PMID:12208513
acetylsalicylic acid	multiple interactions	ISO	RGD:1345686	6480464	Aspirin inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein] more ...	CTD	PMID:15136050, PMID:15379866
acetylsalicylic acid	increases expression	ISO	RGD:1345686	6480464	Aspirin results in increased expression of CXCL8 mRNA	CTD	PMID:15928584
acrolein	decreases secretion	ISO	RGD:1345686	6480464	Acrolein results in decreased secretion of CXCL8 protein	CTD	PMID:28947239
acrolein	increases secretion	ISO	RGD:1345686	6480464	Acrolein results in increased secretion of CXCL8 protein	CTD	PMID:11504702, PMID:30204913
acrolein	decreases expression	ISO	RGD:1345686	6480464	Acrolein results in decreased expression of CXCL8 mRNA, Acrolein results in decreased expression of CXCL8 protein	CTD	PMID:15650393 more ...
acrolein	increases expression	ISO	RGD:1345686	6480464	Acrolein results in increased expression of CXCL8 mRNA	CTD	PMID:18951912
acrolein	multiple interactions	ISO	RGD:1345686	6480464	[Acrolein co-treated with Formaldehyde co-treated with Ozone] results in increased expression of CXCL8 protein more ...	CTD	PMID:11504702 more ...
actinomycin D	increases expression	ISO	RGD:1345686	6480464	Dactinomycin results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
actinomycin D	multiple interactions	ISO	RGD:1345686	6480464	[Dactinomycin co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:12039947 more ...
adenine	multiple interactions	ISO	RGD:1345686	6480464	Adenine inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]	CTD	PMID:18308354
adenosine	multiple interactions	ISO	RGD:1345686	6480464	[Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA], [Adenosine co-treated with Homocysteine] results in decreased expression of CXCL8 mRNA	CTD	PMID:24224954
adenosine 5'-[gamma-thio]triphosphate	multiple interactions	ISO	RGD:1345686	6480464	[adenosine 5'-O-(3-thiotriphosphate) binds to and results in increased activity of P2RY11 protein] which results in increased expression of CXCL8 protein	CTD	PMID:19815812
aflatoxin B1	affects expression	ISO	RGD:1345686	6480464	Aflatoxin B1 affects the expression of CXCL8 protein	CTD	PMID:20106945
aflatoxin B1	increases expression	ISO	RGD:1345686	6480464	Aflatoxin B1 results in increased expression of CXCL8 mRNA	CTD	PMID:21632981 more ...
AICA ribonucleotide	multiple interactions	ISO	RGD:1345686	6480464	AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CXCL8 mRNA]	CTD	PMID:21745629
albendazole	increases expression	ISO	RGD:1345686	6480464	Albendazole results in increased expression of CXCL8 protein	CTD	PMID:20116850
albendazole	multiple interactions	ISO	RGD:1345686	6480464	[Ivermectin co-treated with Albendazole] results in increased expression of CXCL8 protein, U 0126 inhibits the reaction [Albendazole results in increased secretion of CXCL8 protein]	CTD	PMID:16861626, PMID:20848085
albendazole	increases secretion	ISO	RGD:1345686	6480464	Albendazole results in increased secretion of CXCL8 protein	CTD	PMID:20848085
albuterol	multiple interactions	ISO	RGD:1345686	6480464	[Beclomethasone co-treated with Albuterol] results in decreased secretion of CXCL8 protein, Albuterol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:12818968, PMID:15679717
aldehydo-D-glucosamine	multiple interactions	ISO	RGD:1345686	6480464	Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18026701 more ...
aldehydo-D-glucose	increases expression	ISO	RGD:1345686	6480464	Glucose results in increased expression of CXCL8 mRNA, Glucose results in increased expression of CXCL8 protein	CTD	PMID:20578705 more ...
aldehydo-D-glucose	increases secretion	ISO	RGD:1345686	6480464	Glucose results in increased secretion of CXCL8 protein	CTD	PMID:17665966
aldehydo-D-glucose	multiple interactions	ISO	RGD:1345686	6480464	aspalathin inhibits the reaction [Glucose results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:17665966 more ...
alexidine	decreases expression	ISO	RGD:1345686	6480464	alexidine results in decreased expression of CXCL8 protein	CTD	PMID:20116850
all-trans-retinoic acid	multiple interactions	ISO	RGD:1345686	6480464	[Tretinoin co-treated with arsenic trioxide] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:15894607 more ...
all-trans-retinoic acid	increases secretion	ISO	RGD:1345686	6480464	Tretinoin results in increased secretion of CXCL8 protein	CTD	PMID:17235257, PMID:17763283
all-trans-retinoic acid	increases expression	ISO	RGD:1345686	6480464	Tretinoin results in increased expression of CXCL8 mRNA, Tretinoin results in increased expression of CXCL8 protein	CTD	PMID:12875902 more ...
allopurinol	increases expression	ISO	RGD:1345686	6480464	Allopurinol results in increased expression of CXCL8 mRNA	CTD	PMID:25091725, PMID:26641773
allopurinol	multiple interactions	ISO	RGD:1345686	6480464	pyrazolanthrone inhibits the reaction [Allopurinol results in increased expression of CXCL8 mRNA], U 0126 inhibits the reaction [Allopurinol results in increased expression of CXCL8 mRNA]	CTD	PMID:26641773
alloxanthine	increases expression	ISO	RGD:1345686	6480464	Oxypurinol results in increased expression of CXCL8 mRNA	CTD	PMID:25091725, PMID:26641773
alpha-D-galactose	increases expression	ISO	RGD:1345686	6480464	Galactose results in increased expression of CXCL8 mRNA	CTD	PMID:29412148
alpha-D-galactose	multiple interactions	ISO	RGD:1345686	6480464	ginsenoside F1 inhibits the reaction [Galactose results in increased expression of CXCL8 mRNA], ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of CXCL8 protein]	CTD	PMID:29412148
alpha-hexylcinnamaldehyde	increases expression	ISO	RGD:1345686	6480464	alpha-hexylcinnamaldehyde results in increased expression of CXCL8 mRNA, hexyl cinnamic aldehyde results in increased expression of CXCL8 mRNA	CTD	PMID:21920952, PMID:27965148
alpha-naphthoflavone	multiple interactions	ISO	RGD:1345686	6480464	alpha-naphthoflavone inhibits the reaction [3 more ...	CTD	PMID:22262711
alpha-naphthoflavone	decreases expression	ISO	RGD:1345686	6480464	alpha-naphthoflavone results in decreased expression of CXCL8 mRNA	CTD	PMID:22262711
alpha-naphthoflavone	increases expression	ISO	RGD:1345686	6480464	alpha-naphthoflavone results in increased expression of CXCL8 mRNA	CTD	PMID:22262711
aluminium atom	increases expression	ISO	RGD:1345686	6480464	Aluminum analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
aluminium hydroxide	increases secretion	ISO	RGD:1345686	6480464	Aluminum Hydroxide results in increased secretion of CXCL8 protein	CTD	PMID:18390722
aluminium oxide	increases expression	ISO	RGD:1345686	6480464	Aluminum Oxide results in increased expression of CXCL8 mRNA	CTD	PMID:15183442
aluminium(0)	increases expression	ISO	RGD:1345686	6480464	Aluminum analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
aluminium(3+)	increases expression	ISO	RGD:1345686	6480464	Aluminum analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
AM-251	multiple interactions	ISO	RGD:1345686	6480464	AM 251 promotes the reaction [Capsaicin results in increased secretion of CXCL8 protein]	CTD	PMID:20619260
amidotrizoic acid	increases secretion	ISO	RGD:1345686	6480464	Diatrizoate results in increased secretion of CXCL8 protein	CTD	PMID:21036957
amiloride	multiple interactions	ISO	RGD:1345686	6480464	Amiloride inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12065299, PMID:12107048
amiodarone	multiple interactions	ISO	RGD:1345686	6480464	[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:22785256
ammonium hexachloroplatinate	multiple interactions	ISO	RGD:1345686	6480464	SB 203580 affects the reaction [ammonium hexachloroplatinate results in increased secretion of CXCL8 protein]	CTD	PMID:18494145
ammonium hexachloroplatinate	increases secretion	ISO	RGD:1345686	6480464	ammonium hexachloroplatinate results in increased secretion of CXCL8 protein	CTD	PMID:18494145
amorolfine	multiple interactions	ISO	RGD:1345686	6480464	amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]	CTD	PMID:23688403
amoxicillin	increases expression	ISO	RGD:1345686	6480464	Amoxicillin results in increased expression of CXCL8 mRNA, Amoxicillin results in increased expression of CXCL8 protein	CTD	PMID:11390425, PMID:25091725
amphibole asbestos	decreases expression	ISO	RGD:1345686	6480464	Asbestos, Amphibole results in decreased expression of CXCL8 mRNA alternative form	CTD	PMID:20831825
amphibole asbestos	multiple interactions	ISO	RGD:1345686	6480464	Deferoxamine promotes the reaction [Asbestos, Amphibole results in increased expression of CXCL8], Iron inhibits the reaction [Asbestos, Amphibole results in increased expression of CXCL8]	CTD	PMID:21605006
amphibole asbestos	increases expression	ISO	RGD:1345686	6480464	Asbestos, Amphibole results in increased expression of CXCL8 more ...	CTD	PMID:20831825 more ...
amphotericin B	multiple interactions	ISO	RGD:1345686	6480464	[Amphotericin B co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
amphotericin B	increases expression	ISO	RGD:1345686	6480464	Amphotericin B results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
ampicillin	increases expression	ISO	RGD:1345686	6480464	Ampicillin results in increased expression of CXCL8 mRNA	CTD	PMID:25091725
andrographolide	multiple interactions	EXP		6480464	andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CXCL8 mRNA], andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased secretion of CXCL8 protein]	CTD	PMID:31128153
aniline	increases expression	ISO	RGD:1345686	6480464	aniline analog results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
anthra[1,9-cd]pyrazol-6(2H)-one	multiple interactions	ISO	RGD:1345686	6480464	pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12832416 more ...
anthracen-2-amine	increases expression	ISO	RGD:1345686	6480464	2-anthramine results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
anthracene	multiple interactions	ISO	RGD:1345686	6480464	TNF protein promotes the reaction [anthracene results in increased expression of CXCL8 mRNA]	CTD	PMID:18434080
anthracene	increases expression	ISO	RGD:1345686	6480464	anthracene results in increased expression of CXCL8 mRNA	CTD	PMID:18434080
anthracene-1,8,9-triol	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [Anthralin results in increased expression of CXCL8 protein] more ...	CTD	PMID:9628260
anthracene-1,8,9-triol	increases expression	ISO	RGD:1345686	6480464	Anthralin results in increased expression of CXCL8 mRNA, Anthralin results in increased expression of CXCL8 protein	CTD	PMID:9628260
antimycin A	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein] more ...	CTD	PMID:12208513, PMID:22549761
antimycin A	increases expression	ISO	RGD:1345686	6480464	Antimycin A results in increased expression of CXCL8 mRNA, Antimycin A results in increased expression of CXCL8 protein	CTD	PMID:22549761
antimycin A	decreases expression	ISO	RGD:1345686	6480464	Antimycin A results in decreased expression of CXCL8 protein	CTD	PMID:20116850
antirheumatic drug	decreases expression	ISO	RGD:1345686	6480464	Antirheumatic Agents results in decreased expression of CXCL8 mRNA	CTD	PMID:24449571
apocynin	multiple interactions	ISO	RGD:1345686	6480464	acetovanillone inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:20920494 more ...
arachidonic acid	multiple interactions	EXP		6480464	Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA]	CTD	PMID:19063610
arachidonic acid	increases secretion	ISO	RGD:1345686	6480464	Arachidonic Acid results in increased secretion of CXCL8 protein	CTD	PMID:21457203
arachidonic acid	multiple interactions	ISO	RGD:1345686	6480464	CNR2 protein affects the reaction [Arachidonic Acid results in increased expression of CXCL8 protein]	CTD	PMID:15115777
arecoline	increases secretion	ISO	RGD:1345686	6480464	Arecoline results in increased secretion of CXCL8 protein	CTD	PMID:21297082
Aroclor 1254	decreases expression	ISO	RGD:1345686	6480464	Chlorodiphenyl (54% Chlorine) results in decreased expression of CXCL8 mRNA	CTD	PMID:17851650
arsane	increases expression	ISO	RGD:1345686	6480464	Arsenic results in increased expression of CXCL8 protein	CTD	PMID:16084078
arsane	multiple interactions	ISO	RGD:1345686	6480464	Arsenic affects the reaction [GSTO1 gene alternative form results in increased expression of CXCL8 mRNA]	CTD	PMID:22293942
arsenic acid	increases secretion	ISO	RGD:1345686	6480464	arsenic acid results in increased secretion of CXCL8 protein	CTD	PMID:29355690
arsenic atom	multiple interactions	ISO	RGD:1345686	6480464	Arsenic affects the reaction [GSTO1 gene alternative form results in increased expression of CXCL8 mRNA]	CTD	PMID:22293942
arsenic atom	increases expression	ISO	RGD:1345686	6480464	Arsenic results in increased expression of CXCL8 protein	CTD	PMID:16084078
arsenic(3+)	increases expression	ISO	RGD:1345686	6480464	Arsenic results in increased expression of CXCL8 protein	CTD	PMID:16084078
arsenic(3+)	multiple interactions	ISO	RGD:1345686	6480464	Arsenic affects the reaction [GSTO1 gene alternative form results in increased expression of CXCL8 mRNA]	CTD	PMID:22293942
arsenite(3-)	increases expression	ISO	RGD:1345686	6480464	arsenite results in increased expression of CXCL8 mRNA, arsenite results in increased expression of CXCL8 protein	CTD	PMID:18418899, PMID:25257954
arsenite(3-)	affects expression	ISO	RGD:1345686	6480464	arsenite affects the expression of CXCL8 mRNA	CTD	PMID:22959463
arsenite(3-)	multiple interactions	ISO	RGD:1345686	6480464	[arsenite results in increased activity of [NFKB1 protein binds to RELB protein]] which results in increased expression of CXCL8 mRNA more ...	CTD	PMID:10775461 more ...
arsenite(3-)	decreases expression	ISO	RGD:1345686	6480464	arsenite results in decreased expression of CXCL8 mRNA	CTD	PMID:16085347
asbestos	increases expression	ISO	RGD:1345686	6480464	Asbestos results in increased expression of CXCL8 mRNA, Asbestos results in increased expression of CXCL8 protein	CTD	PMID:22076105 more ...
aspalathin	multiple interactions	ISO	RGD:1345686	6480464	aspalathin inhibits the reaction [Glucose results in increased expression of CXCL8 mRNA], aspalathin inhibits the reaction [Glucose results in increased expression of CXCL8 protein]	CTD	PMID:25338943
asperentin	decreases expression	EXP		6480464	cladosporin results in decreased expression of CXCL15 mRNA	CTD	PMID:19818335
atorvastatin calcium	decreases secretion	ISO	RGD:1345686	6480464	Atorvastatin results in decreased secretion of CXCL8 protein	CTD	PMID:16387846
atorvastatin calcium	multiple interactions	ISO	RGD:1345686	6480464	Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12117737 more ...
atorvastatin calcium	decreases expression	ISO	RGD:1345686	6480464	Atorvastatin results in decreased expression of CXCL8 mRNA, Atorvastatin results in decreased expression of CXCL8 protein	CTD	PMID:12117737, PMID:16410222
atorvastatin calcium	increases expression	ISO	RGD:1345686	6480464	Atorvastatin results in increased expression of CXCL8 protein	CTD	PMID:19171469
atrazine	decreases expression	EXP		6480464	Atrazine results in decreased expression of CXCL15 protein	CTD	PMID:12504806
Augmentin	increases expression	ISO	RGD:1345686	6480464	Amoxicillin-Potassium Clavulanate Combination results in increased expression of CXCL8 protein	CTD	PMID:11390425
avobenzone	increases expression	ISO	RGD:1345686	6480464	avobenzone results in increased expression of CXCL8 protein	CTD	PMID:25617811
azathioprine	increases expression	ISO	RGD:1345686	6480464	Azathioprine results in increased expression of CXCL8 mRNA	CTD	PMID:22623647
azathioprine	decreases expression	ISO	RGD:1345686	6480464	Azathioprine results in decreased expression of CXCL8 mRNA, Azathioprine results in decreased expression of CXCL8 protein	CTD	PMID:19192274
aziridines	decreases expression	ISO	RGD:1345686	6480464	Aziridines analog results in decreased expression of CXCL8 mRNA	CTD	PMID:16243974
azithromycin	multiple interactions	ISO	RGD:1345686	6480464	Azithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA], Azithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:21417583
Bandrowski's base	affects expression	ISO	RGD:1345686	6480464	Bandrowski's base affects the expression of CXCL8 mRNA	CTD	PMID:18202158
beclomethasone	multiple interactions	ISO	RGD:1345686	6480464	[Beclomethasone co-treated with Albuterol] results in decreased secretion of CXCL8 protein more ...	CTD	PMID:14643170, PMID:15679717
beclomethasone	decreases expression	ISO	RGD:1345686	6480464	Beclomethasone results in decreased expression of CXCL8 protein	CTD	PMID:11015126
belinostat	increases expression	ISO	RGD:1345686	6480464	belinostat results in increased expression of CXCL8 mRNA	CTD	PMID:23671600
benomyl	increases expression	ISO	RGD:1345686	6480464	Benomyl results in increased expression of CXCL8 mRNA	CTD	PMID:27784618
benomyl	multiple interactions	ISO	RGD:1345686	6480464	ORMDL3 protein affects the reaction [Benomyl results in increased expression of CXCL8 mRNA]	CTD	PMID:27784618
benzalkonium chloride	decreases expression	ISO	RGD:1345686	6480464	Benzalkonium Compounds results in decreased expression of CXCL8 protein	CTD	PMID:25290854, PMID:8006454
benzalkonium chloride	increases expression	ISO	RGD:1345686	6480464	Benzalkonium Compounds results in increased expression of CXCL8 mRNA	CTD	PMID:12781210 more ...
benzalkonium chloride	decreases secretion	ISO	RGD:1345686	6480464	Benzalkonium Compounds results in decreased secretion of CXCL8 protein	CTD	PMID:16099135
benzalkonium chloride	increases secretion	ISO	RGD:1345686	6480464	Benzalkonium Compounds results in increased secretion of CXCL8 protein	CTD	PMID:12781210 more ...
benzene	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [Benzene results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:11306435
benzene	multiple interactions	EXP		6480464	[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in increased expression of CXCL15 protein	CTD	PMID:24733833
benzene	increases expression	ISO	RGD:1345686	6480464	Benzene metabolite results in increased expression of CXCL8 protein more ...	CTD	PMID:11306435 more ...
benzene-1,2,4-triol	affects expression	ISO	RGD:1345686	6480464	hydroxyhydroquinone affects the expression of CXCL8 protein	CTD	PMID:17572062
benzene-1,2,4-triol	increases expression	ISO	RGD:1345686	6480464	hydroxyhydroquinone results in increased expression of CXCL8 mRNA	CTD	PMID:24530881
benzene-1,2,4-triol	multiple interactions	ISO	RGD:1345686	6480464	4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL8 mRNA]	CTD	PMID:24530881
benzethonium chloride	increases expression	ISO	RGD:1345686	6480464	Benzethonium results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
benzethonium chloride	decreases expression	ISO	RGD:1345686	6480464	Benzethonium results in decreased expression of CXCL8 protein	CTD	PMID:20116850
benzo[a]pyrene	decreases metabolic processing	ISO	RGD:1345686	6480464	CXCL8 protein results in decreased metabolism of Benzo(a)pyrene	CTD	PMID:28238931
benzo[a]pyrene	decreases expression	ISO	RGD:1345686	6480464	Benzo(a)pyrene metabolite results in decreased expression of CXCL8 mRNA, Benzo(a)pyrene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284, PMID:26314263
benzo[a]pyrene	increases secretion	ISO	RGD:1345686	6480464	Benzo(a)pyrene results in increased secretion of CXCL8 protein	CTD	PMID:22404339, PMID:29787794
benzo[a]pyrene	increases expression	ISO	RGD:1345686	6480464	Benzo(a)pyrene results in increased expression of CXCL8 more ...	CTD	PMID:11306435 more ...
benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of CXCL15 mRNA	CTD	PMID:20713471
benzo[a]pyrene	multiple interactions	ISO	RGD:1345686	6480464	[Benzo(a)pyrene co-treated with CXCL8 protein] results in decreased abundance of NADP more ...	CTD	PMID:11306435 more ...
benzo[a]pyrene diol epoxide I	multiple interactions	ISO	RGD:1345686	6480464	[Asbestos, Serpentine co-treated with 7 more ...	CTD	PMID:18197826
benzo[a]pyrene diol epoxide I	increases expression	ISO	RGD:1345686	6480464	7 more ...	CTD	PMID:19150397, PMID:20382639
benzo[b]fluoranthene	increases expression	ISO	RGD:1345686	6480464	benzo(b)fluoranthene results in increased expression of CXCL8 mRNA	CTD	PMID:29787794
benzo[b]fluoranthene	decreases expression	ISO	RGD:1345686	6480464	benzo(b)fluoranthene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
benzo[b]fluoranthene	increases secretion	ISO	RGD:1345686	6480464	benzo(b)fluoranthene results in increased secretion of CXCL8 protein	CTD	PMID:29787794
benzo[c]phenanthrene	decreases expression	ISO	RGD:1345686	6480464	benzo(c)phenanthrene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
Benzo[k]fluoranthene	decreases expression	ISO	RGD:1345686	6480464	benzo(k)fluoranthene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
benzofurans	multiple interactions	ISO	RGD:1345686	6480464	Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CXCL8 protein], Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA]	CTD	PMID:30696844
benzoic acid	increases expression	ISO	RGD:1345686	6480464	Benzoic Acid results in increased expression of CXCL8 mRNA	CTD	PMID:12781210
Benzoyl peroxide	increases expression	ISO	RGD:1345686	6480464	Benzoyl Peroxide results in increased expression of CXCL8 mRNA	CTD	PMID:21920952, PMID:27965148
benzyl benzoate	increases expression	ISO	RGD:1345686	6480464	benzyl benzoate results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
benzyl bromide	increases expression	ISO	RGD:1345686	6480464	benzyl bromide results in increased expression of CXCL8 mRNA	CTD	PMID:20713136
benzylpenicillin	multiple interactions	ISO	RGD:1345686	6480464	SB 203580 affects the reaction [Penicillin G results in increased secretion of CXCL8 protein]	CTD	PMID:18494145
benzylpenicillin	increases expression	ISO	RGD:1345686	6480464	Penicillin G results in increased expression of CXCL8 mRNA, Penicillin G results in increased expression of CXCL8 protein	CTD	PMID:22609641, PMID:27965148
benzylpenicillin	increases secretion	ISO	RGD:1345686	6480464	Penicillin G results in increased secretion of CXCL8 protein	CTD	PMID:18494145
berberine	multiple interactions	ISO	RGD:1345686	6480464	Berberine inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:16391493, PMID:28916288
beta-carotene	multiple interactions	ISO	RGD:1345686	6480464	beta Carotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CXCL8 protein]	CTD	PMID:19135038
beta-D-glucosamine	multiple interactions	ISO	RGD:1345686	6480464	Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18026701 more ...
betamethasone	multiple interactions	ISO	RGD:1345686	6480464	Betamethasone inhibits the reaction [cinnamic aldehyde results in increased expression of CXCL8 mRNA], Betamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA]	CTD	PMID:20090409
bezafibrate	multiple interactions	ISO	RGD:1345686	6480464	Bezafibrate inhibits the reaction [Palmitic Acid results in increased expression of CXCL8 mRNA]	CTD	PMID:21745629
bilirubin IXalpha	multiple interactions	ISO	RGD:1345686	6480464	EIF2AK3 mRNA promotes the reaction [Bilirubin results in increased expression of CXCL8 mRNA], prolinedithiocarbamate inhibits the reaction [Bilirubin results in increased expression of CXCL8 mRNA]	CTD	PMID:27578021
bilirubin IXalpha	increases expression	ISO	RGD:1345686	6480464	Bilirubin results in increased expression of CXCL8 mRNA, Bilirubin results in increased expression of CXCL8 protein	CTD	PMID:27578021
biochanin A	multiple interactions	ISO	RGD:1345686	6480464	biochanin A inhibits the reaction [CXCL8 protein results in increased expression of ICAM1 protein] more ...	CTD	PMID:22387535
bis(2-chloroethyl) sulfide	multiple interactions	ISO	RGD:1345686	6480464	Berberine inhibits the reaction [Mustard Gas results in increased secretion of CXCL8 protein] more ...	CTD	PMID:12083423 more ...
bis(2-chloroethyl) sulfide	increases secretion	ISO	RGD:1345686	6480464	Mustard Gas results in increased secretion of CXCL8 protein	CTD	PMID:12753408 more ...
bis(2-chloroethyl) sulfide	increases expression	ISO	RGD:1345686	6480464	Mustard Gas results in increased expression of CXCL8 mRNA, Mustard Gas results in increased expression of CXCL8 protein	CTD	PMID:10025362 more ...
bis(2-chloroethyl) sulfide	affects expression	ISO	RGD:1345686	6480464	Mustard Gas affects the expression of CXCL8 protein	CTD	PMID:19748996
bis(2-ethylhexyl) phthalate	increases expression	ISO	RGD:1345686	6480464	Diethylhexyl Phthalate results in increased expression of CXCL8 mRNA	CTD	PMID:23724284, PMID:28412506
bisphenol A	multiple interactions	ISO	RGD:1345686	6480464	4-(6-bromo-1 more ...	CTD	PMID:28628672 more ...
bisphenol A	increases secretion	ISO	RGD:1345686	6480464	bisphenol A results in increased secretion of CXCL8 protein	CTD	PMID:26133781
bisphenol A	increases expression	ISO	RGD:1345686	6480464	bisphenol A results in increased expression of CXCL8 mRNA	CTD	PMID:25619500 more ...
bisphenol A	decreases expression	ISO	RGD:1345686	6480464	bisphenol A results in decreased expression of CXCL8 mRNA, bisphenol A results in decreased expression of CXCL8 protein	CTD	PMID:25878060, PMID:28736254
Bisphenol A diglycidyl ether	increases expression	ISO	RGD:1345686	6480464	2, 2-bis(4-glycidyloxyphenyl)propane results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
Bisphenol A glycidylmethacrylate	increases expression	ISO	RGD:1345686	6480464	Bisphenol A-Glycidyl Methacrylate results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
bleomycin A2	multiple interactions	ISO	RGD:1345686	6480464	[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein, [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of CXCL8 protein	CTD	PMID:14617519
bleomycin A2	increases expression	ISO	RGD:1345686	6480464	Bleomycin results in increased expression of CXCL8 mRNA, Bleomycin results in increased expression of CXCL8 protein	CTD	PMID:18684396
bortezomib	multiple interactions	ISO	RGD:1345686	6480464	Bortezomib inhibits the reaction [vorinostat results in increased expression of CXCL8 mRNA]	CTD	PMID:15514602
bortezomib	increases secretion	ISO	RGD:1345686	6480464	Bortezomib results in increased secretion of CXCL8 protein	CTD	PMID:17172406
bortezomib	increases expression	ISO	RGD:1345686	6480464	Bortezomib results in increased expression of CXCL8 mRNA	CTD	PMID:15509775
bosentan	increases expression	ISO	RGD:1345686	6480464	Bosentan results in increased expression of CXCL8 mRNA	CTD	PMID:29761207
Brevetoxin B	increases expression	ISO	RGD:1345686	6480464	brevetoxin 2 results in increased expression of CXCL8 mRNA	CTD	PMID:20498034
bromobenzene	increases secretion	ISO	RGD:1345686	6480464	bromobenzene analog results in increased secretion of CXCL8 protein	CTD	PMID:19427879
bucladesine	multiple interactions	ISO	RGD:1345686	6480464	Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:9258252
budesonide	multiple interactions	ISO	RGD:1345686	6480464	Budesonide inhibits the reaction [TNF protein results in increased secretion of CXCL8 mRNA], Budesonide inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]	CTD	PMID:14643170
butan-1-ol	multiple interactions	ISO	RGD:1345686	6480464	1-Butanol inhibits the reaction [sphingosine 1-phosphate results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12039947, PMID:29432896
butanal	increases expression	ISO	RGD:1345686	6480464	butyraldehyde results in increased expression of CXCL8 mRNA	CTD	PMID:26079696
butanal	increases secretion	ISO	RGD:1345686	6480464	butyraldehyde results in increased secretion of CXCL8 protein	CTD	PMID:26079696
butane-2,3-dione	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Diacetyl results in increased expression of and results in increased secretion of IL8 protein] more ...	CTD	PMID:30851105
butane-2,3-dione	affects expression	ISO	RGD:1345686	6480464	Diacetyl analog affects the expression of CXCL8 mRNA	CTD	PMID:20200221
butenafine	multiple interactions	ISO	RGD:1345686	6480464	butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]	CTD	PMID:23688403
Butylbenzyl phthalate	increases expression	ISO	RGD:1345686	6480464	butylbenzyl phthalate results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
butyric acid	multiple interactions	ISO	RGD:1345686	6480464	[Butyric Acid co-treated with Glucans] results in increased secretion of CXCL8 protein, [Butyric Acid co-treated with Zymosan] results in increased secretion of CXCL8 protein	CTD	PMID:15196572
butyric acid	increases secretion	ISO	RGD:1345686	6480464	Butyric Acid results in increased secretion of CXCL8 protein	CTD	PMID:15196572
butyric acid	increases expression	ISO	RGD:1345686	6480464	Butyric Acid results in increased expression of CXCL8 mRNA	CTD	PMID:15196572, PMID:17928716
cadmium atom	multiple interactions	ISO	RGD:1345686	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CXCL8 mRNA more ...	CTD	PMID:29741670, PMID:8123758
cadmium atom	increases expression	ISO	RGD:1345686	6480464	Cadmium results in increased expression of CXCL8 mRNA, Cadmium results in increased expression of CXCL8 protein	CTD	PMID:20105457 more ...
cadmium dichloride	multiple interactions	ISO	RGD:1345686	6480464	[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:17391980 more ...
cadmium dichloride	increases expression	ISO	RGD:1345686	6480464	Cadmium Chloride results in increased expression of CXCL8 mRNA, Cadmium Chloride results in increased expression of CXCL8 protein	CTD	PMID:15033544 more ...
cadmium dichloride	increases secretion	ISO	RGD:1345686	6480464	Cadmium Chloride results in increased secretion of CXCL8 protein	CTD	PMID:17391980 more ...
cadmium sulfate	increases expression	ISO	RGD:1345686	6480464	cadmium sulfate results in increased expression of CXCL8 mRNA, cadmium sulfate results in increased expression of CXCL8 protein	CTD	PMID:21783983 more ...
cadmium sulfate	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein] more ...	CTD	PMID:22094458, PMID:22142850
cadmium sulfate	increases secretion	ISO	RGD:1345686	6480464	cadmium sulfate results in increased secretion of CXCL8 protein	CTD	PMID:22094458, PMID:22142850
caffeine	increases expression	ISO	RGD:1345686	6480464	Caffeine results in increased expression of CXCL8 mRNA	CTD	PMID:28089782
Calcimycin	multiple interactions	ISO	RGD:1345686	6480464	3 more ...	CTD	PMID:12789233 more ...
Calcimycin	increases expression	ISO	RGD:1345686	6480464	Calcimycin results in increased expression of CXCL8 mRNA	CTD	PMID:12789233
calcitriol	multiple interactions	ISO	RGD:1345686	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:12753408 more ...
calcitriol	increases expression	ISO	RGD:1345686	6480464	Calcitriol results in increased expression of CXCL8 mRNA	CTD	PMID:12875902 more ...
calcitriol	decreases expression	ISO	RGD:1345686	6480464	Calcitriol results in decreased expression of CXCL8 mRNA	CTD	PMID:16002434
calcium atom	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:11298490 more ...
calcium atom	increases uptake	ISO	RGD:1345686	6480464	CXCL8 protein results in increased uptake of Calcium	CTD	PMID:10984371
calcium atom	increases abundance	ISO	RGD:1345686	6480464	CXCL8 protein results in increased abundance of Calcium	CTD	PMID:15748943
calcium(0)	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:11298490 more ...
calcium(0)	increases uptake	ISO	RGD:1345686	6480464	CXCL8 protein results in increased uptake of Calcium	CTD	PMID:10984371
calcium(0)	increases abundance	ISO	RGD:1345686	6480464	CXCL8 protein results in increased abundance of Calcium	CTD	PMID:15748943
camptothecin	decreases expression	ISO	RGD:1345686	6480464	Camptothecin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
camptothecin	decreases response to substance	ISO	RGD:1345686	6480464	CXCL8 protein results in decreased susceptibility to Camptothecin	CTD	PMID:16356833
camptothecin	multiple interactions	ISO	RGD:1345686	6480464	Ciprofloxacin inhibits the reaction [Camptothecin results in increased secretion of CXCL8 protein], moxifloxacin inhibits the reaction [Camptothecin results in increased secretion of CXCL8 protein]	CTD	PMID:18191106
camptothecin	increases secretion	ISO	RGD:1345686	6480464	Camptothecin results in increased secretion of CXCL8 protein	CTD	PMID:18191106
candesartan	decreases expression	ISO	RGD:1345686	6480464	candesartan results in decreased expression of CXCL8	CTD	PMID:16675585
canertinib	decreases secretion	ISO	RGD:1345686	6480464	Canertinib results in decreased secretion of CXCL8 protein	CTD	PMID:15956251
canertinib	decreases expression	ISO	RGD:1345686	6480464	Canertinib results in decreased expression of CXCL8 mRNA, Canertinib results in decreased expression of CXCL8 protein	CTD	PMID:15956251
capsaicin	multiple interactions	ISO	RGD:1345686	6480464	5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein] more ...	CTD	PMID:12034025 more ...
capsaicin	increases secretion	ISO	RGD:1345686	6480464	Capsaicin results in increased secretion of CXCL8 protein	CTD	PMID:20619260, PMID:22171160
capsaicin	increases expression	ISO	RGD:1345686	6480464	Capsaicin results in increased expression of CXCL8 mRNA	CTD	PMID:16173059
capsaicin	decreases expression	ISO	RGD:1345686	6480464	Capsaicin results in decreased expression of CXCL8 protein	CTD	PMID:12034025
capsaicin	affects expression	ISO	RGD:1345686	6480464	Capsaicin affects the expression of CXCL8 mRNA	CTD	PMID:17760719
capsazepine	multiple interactions	ISO	RGD:1345686	6480464	capsazepine inhibits the reaction [Capsaicin results in increased expression of CXCL8 mRNA], capsazepine inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]	CTD	PMID:16173059, PMID:20619260
carazolol	multiple interactions	ISO	RGD:1345686	6480464	carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of CXCL8 mRNA]	CTD	PMID:30503853
carbamate ester	increases expression	ISO	RGD:1345686	6480464	Carbamates analog results in increased expression of CXCL8 protein	CTD	PMID:19111005, PMID:19376255
carbamate ester	increases secretion	ISO	RGD:1345686	6480464	Carbamates results in increased secretion of CXCL8 protein	CTD	PMID:19455394
carbamazepine	affects expression	ISO	RGD:1345686	6480464	Carbamazepine affects the expression of CXCL8 mRNA	CTD	PMID:24752500
carbon nanotube	increases expression	ISO	RGD:1345686	6480464	Nanotubes, Carbon analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:20371264 more ...
carbon nanotube	increases secretion	ISO	RGD:1345686	6480464	Nanotubes, Carbon analog results in increased secretion of CXCL8 protein, Nanotubes, Carbon results in increased secretion of CXCL8 protein	CTD	PMID:19268679 more ...
carbon nanotube	decreases secretion	ISO	RGD:1345686	6480464	Nanotubes, Carbon analog results in decreased secretion of CXCL8 protein	CTD	PMID:19041333
carbon nanotube	decreases expression	ISO	RGD:1345686	6480464	Nanotubes, Carbon analog results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:19041333, PMID:23634900
carbon nanotube	increases expression	EXP		6480464	Nanotubes, Carbon results in increased expression of CXCL15 protein	CTD	PMID:21135415
carbon nanotube	multiple interactions	ISO	RGD:1345686	6480464	[Nanotubes, Carbon co-treated with calfactant] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:19041333 more ...
carrageenan	increases expression	ISO	RGD:1345686	6480464	Carrageenan results in increased expression of CXCL8 mRNA, Carrageenan results in increased expression of CXCL8 protein	CTD	PMID:22561171
carrageenan	multiple interactions	ISO	RGD:1345686	6480464	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Carrageenan results in increased expression of CXCL8 mRNA], 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Carrageenan results in increased expression of CXCL8 protein]	CTD	PMID:22561171
catechin	multiple interactions	ISO	RGD:1345686	6480464	[Catechin co-treated with tert-Butylhydroperoxide co-treated with Hydrocortisone] results in decreased secretion of CXCL8 protein	CTD	PMID:29935159
catechol	increases expression	ISO	RGD:1345686	6480464	catechol results in increased expression of CXCL8 protein	CTD	PMID:15356918, PMID:17572062
celecoxib	increases expression	ISO	RGD:1345686	6480464	Celecoxib results in increased expression of CXCL8 protein	CTD	PMID:11390425
cephaeline	decreases expression	ISO	RGD:1345686	6480464	cephaelin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
ceric oxide	multiple interactions	ISO	RGD:1345686	6480464	[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CXCL8 mRNA	CTD	PMID:29792201
ceric oxide	increases expression	ISO	RGD:1345686	6480464	ceric oxide analog results in increased expression of CXCL8 mRNA	CTD	PMID:27060086
ceric oxide	increases secretion	ISO	RGD:1345686	6480464	ceric oxide analog results in increased secretion of CXCL8 protein	CTD	PMID:27060086
cerium trichloride	increases expression	EXP		6480464	cerous chloride results in increased expression of CXCL15	CTD	PMID:23712967
cerivastatin	multiple interactions	ISO	RGD:1345686	6480464	cerivastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12117737
cerivastatin	decreases expression	ISO	RGD:1345686	6480464	cerivastatin results in decreased expression of CXCL8 mRNA	CTD	PMID:12117737
cetirizine	multiple interactions	ISO	RGD:1345686	6480464	[montelukast co-treated with Cetirizine] results in decreased expression of CXCL8 protein	CTD	PMID:15061398
cetylpyridinium	affects expression	ISO	RGD:1345686	6480464	Cetylpyridinium affects the expression of CXCL8 protein	CTD	PMID:25290854
chelerythrine	multiple interactions	ISO	RGD:1345686	6480464	[AG 1879 co-treated with chelerythrine] inhibits the reaction [CXCL8 protein results in increased secretion of MMP9 protein] more ...	CTD	PMID:15831558, PMID:19074641
chlorendic acid	increases expression	ISO	RGD:1345686	6480464	chlorendic acid results in increased expression of CXCL8 mRNA	CTD	PMID:22952646
chlorobenzene	increases expression	ISO	RGD:1345686	6480464	chlorobenzene results in increased expression of CXCL8 protein	CTD	PMID:17993253 more ...
chloroform	increases expression	ISO	RGD:1345686	6480464	Chloroform results in increased expression of CXCL8 protein	CTD	PMID:11306435
chloromethylisothiazolinone	increases expression	ISO	RGD:1345686	6480464	5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of CXCL8 mRNA	CTD	PMID:20491607, PMID:20713136
chloropicrin	decreases expression	ISO	RGD:1345686	6480464	chloropicrin results in decreased expression of IL8 mRNA	CTD	PMID:28476498
chloropicrin	affects expression	ISO	RGD:1345686	6480464	chloropicrin affects the expression of CXCL8 mRNA	CTD	PMID:26352163
chloroprene	decreases expression	EXP		6480464	Chloroprene results in decreased expression of CXCL15 mRNA	CTD	PMID:23125180
chloroquine	multiple interactions	ISO	RGD:1345686	6480464	[Chloroquine co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:15139008, PMID:29594315
chloroquine	increases expression	ISO	RGD:1345686	6480464	Chloroquine results in increased expression of CXCL8 mRNA	CTD	PMID:15139008, PMID:29594315
chlorpromazine	multiple interactions	ISO	RGD:1345686	6480464	[Chlorpromazine co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
chlorpromazine	increases expression	ISO	RGD:1345686	6480464	Chlorpromazine results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
chlorpyrifos	multiple interactions	ISO	RGD:1345686	6480464	[TNF protein co-treated with Chlorpyrifos] results in decreased expression of CXCL8 mRNA	CTD	PMID:19589100
cholesterol	multiple interactions	ISO	RGD:1345686	6480464	[methyl-beta-cyclodextrin results in decreased abundance of Cholesterol] inhibits the reaction [Polystyrenes inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]]	CTD	PMID:23274767
chromium atom	multiple interactions	ISO	RGD:1345686	6480464	Chromium inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]	CTD	PMID:10593907
chromium atom	increases expression	ISO	RGD:1345686	6480464	Chromium analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
chromium trioxide	decreases expression	ISO	RGD:1345686	6480464	chromium trioxide results in decreased expression of CXCL8 protein	CTD	PMID:8006454
chromium(3+)	increases expression	ISO	RGD:1345686	6480464	Chromium analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
chromium(3+)	multiple interactions	ISO	RGD:1345686	6480464	Chromium inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]	CTD	PMID:10593907
chromium(3+) trichloride	increases expression	ISO	RGD:1345686	6480464	chromic chloride results in increased expression of CXCL8 protein	CTD	PMID:23629852
chromium(3+) trichloride	multiple interactions	ISO	RGD:1345686	6480464	chromic chloride inhibits the reaction [Glucose results in increased secretion of CXCL8 protein]	CTD	PMID:17665966
chromium(6+)	increases expression	ISO	RGD:1345686	6480464	chromium hexavalent ion results in increased expression of CXCL8 mRNA	CTD	PMID:23748240, PMID:27793765
chromium(6+)	increases secretion	ISO	RGD:1345686	6480464	chromium hexavalent ion results in increased secretion of CXCL8 protein	CTD	PMID:25448439
chromium(6+)	multiple interactions	ISO	RGD:1345686	6480464	Luteolin inhibits the reaction [chromium hexavalent ion results in increased secretion of CXCL8 protein] more ...	CTD	PMID:23748240, PMID:25448439
chrysene	increases expression	ISO	RGD:1345686	6480464	chrysene results in increased expression of CXCL8 mRNA	CTD	PMID:25433334
chrysin	multiple interactions	ISO	RGD:1345686	6480464	chrysin inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]	CTD	PMID:18377686
chrysin	increases expression	ISO	RGD:1345686	6480464	chrysin results in increased expression of CXCL8 mRNA	CTD	PMID:18457675
chrysin 5,7-dimethyl ether	multiple interactions	ISO	RGD:1345686	6480464	5, 7-dimethoxyflavone inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]	CTD	PMID:24134915
cimetidine	multiple interactions	ISO	RGD:1345686	6480464	Cimetidine inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein], Cimetidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 protein]	CTD	PMID:12065299, PMID:12107048
cinnamyl alcohol	increases expression	ISO	RGD:1345686	6480464	cinnamyl alcohol results in increased expression of CXCL8 mRNA, cinnamyl alcohol results in increased expression of CXCL8 protein	CTD	PMID:21920952 more ...
ciprofloxacin	multiple interactions	ISO	RGD:1345686	6480464	Ciprofloxacin affects the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:11052920 more ...
ciprofloxacin	decreases secretion	ISO	RGD:1345686	6480464	Ciprofloxacin results in decreased secretion of CXCL8 protein	CTD	PMID:18191106
cis-caffeic acid	multiple interactions	ISO	RGD:1345686	6480464	caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA], caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:17636245
cisplatin	decreases response to substance	ISO	RGD:1345686	6480464	CXCL8 results in decreased susceptibility to Cisplatin	CTD	PMID:21742513
cisplatin	multiple interactions	EXP		6480464	3-(5-(2, 3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Cisplatin results in increased expression of CXCL15 protein]	CTD	PMID:25308879
cisplatin	increases expression	ISO	RGD:1345686	6480464	Cisplatin results in increased expression of CXCL8 mRNA	CTD	PMID:27594783, PMID:29594315
cisplatin	decreases expression	ISO	RGD:1345686	6480464	Cisplatin results in decreased expression of CXCL8 mRNA	CTD	PMID:19561079
cisplatin	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [CXCL8 results in decreased susceptibility to Cisplatin] more ...	CTD	PMID:20705681 more ...
citral	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [citral results in increased expression of CXCL8 mRNA]	CTD	PMID:21920952
citral	increases secretion	ISO	RGD:1345686	6480464	citral results in increased secretion of CXCL8 protein	CTD	PMID:20541004
citral	increases expression	ISO	RGD:1345686	6480464	citral results in increased expression of CXCL8 mRNA, citral results in increased expression of CXCL8 protein	CTD	PMID:21920952 more ...
cladribine	increases expression	ISO	RGD:1345686	6480464	Cladribine results in increased expression of CXCL8 protein	CTD	PMID:10540334
clarithromycin	increases expression	ISO	RGD:1345686	6480464	Clarithromycin results in increased expression of CXCL8 protein	CTD	PMID:11390425
clenbuterol	multiple interactions	ISO	RGD:1345686	6480464	Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]	CTD	PMID:15502056
clonazepam	multiple interactions	ISO	RGD:1345686	6480464	Clonazepam affects the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased expression of CXCL8 protein]	CTD	PMID:23266380
clonidine	multiple interactions	ISO	RGD:1345686	6480464	Clonidine inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein], Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 protein]	CTD	PMID:12065299, PMID:12107048
clonidine (amino form)	multiple interactions	ISO	RGD:1345686	6480464	Clonidine inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein], Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 protein]	CTD	PMID:12065299, PMID:12107048
clonidine (imino form)	multiple interactions	ISO	RGD:1345686	6480464	Clonidine inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein], Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 protein]	CTD	PMID:12065299, PMID:12107048
clotrimazole	increases expression	ISO	RGD:1345686	6480464	Clotrimazole results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
cobalt atom	increases expression	ISO	RGD:1345686	6480464	Cobalt results in increased expression of CXCL8 mRNA	CTD	PMID:19132727
cobalt atom	increases secretion	ISO	RGD:1345686	6480464	Cobalt results in increased secretion of CXCL8 protein	CTD	PMID:19132727
cobalt dichloride	multiple interactions	ISO	RGD:1345686	6480464	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:17082639 more ...
cobalt dichloride	decreases expression	ISO	RGD:1345686	6480464	cobaltous chloride results in decreased expression of CXCL8 mRNA	CTD	PMID:26314263
cobalt dichloride	increases secretion	ISO	RGD:1345686	6480464	cobaltous chloride results in increased secretion of CXCL8 protein	CTD	PMID:16099135 more ...
cobalt dichloride	increases expression	ISO	RGD:1345686	6480464	cobaltous chloride results in increased expression of CXCL8 mRNA, cobaltous chloride results in increased expression of CXCL8 protein	CTD	PMID:17082639 more ...
cobalt(2+)	increases expression	ISO	RGD:1345686	6480464	Cobalt results in increased expression of CXCL8 mRNA	CTD	PMID:19132727
cobalt(2+)	increases secretion	ISO	RGD:1345686	6480464	Cobalt results in increased secretion of CXCL8 protein	CTD	PMID:19132727
cobalt(2+) sulfate	increases expression	ISO	RGD:1345686	6480464	cobalt sulfate results in increased expression of CXCL8 mRNA	CTD	PMID:20713136
cocaine	increases secretion	ISO	RGD:1345686	6480464	Cocaine results in increased secretion of CXCL8 protein	CTD	PMID:10065903
codeine	multiple interactions	ISO	RGD:1345686	6480464	Codeine affects the secretion of and affects the expression of CXCL8 protein	CTD	PMID:17441793
Colforsin dapropate hydrochloride	multiple interactions	ISO	RGD:1345686	6480464	[Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 mRNA more ...	CTD	PMID:17823304, PMID:23526216
Colforsin dapropate hydrochloride	multiple interactions	EXP		6480464	Colforsin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA]	CTD	PMID:19063610
conjugated linoleic acid	increases expression	ISO	RGD:1345686	6480464	Linoleic Acids, Conjugated results in increased expression of CXCL8 mRNA	CTD	PMID:18776171
conjugated linoleic acid	multiple interactions	ISO	RGD:1345686	6480464	resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased expression of CXCL8 mRNA]	CTD	PMID:18776171
copper atom	multiple interactions	ISO	RGD:1345686	6480464	[NSC 689534 binds to Copper] which results in increased expression of CXCL8 mRNA more ...	CTD	PMID:12432545 more ...
copper atom	increases secretion	ISO	RGD:1345686	6480464	Copper results in increased secretion of CXCL8 protein	CTD	PMID:22981796
copper atom	increases expression	ISO	RGD:1345686	6480464	Copper analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:12432545 more ...
copper(0)	multiple interactions	ISO	RGD:1345686	6480464	[NSC 689534 binds to Copper] which results in increased expression of CXCL8 mRNA more ...	CTD	PMID:12432545 more ...
copper(0)	increases secretion	ISO	RGD:1345686	6480464	Copper results in increased secretion of CXCL8 protein	CTD	PMID:22981796
copper(0)	increases expression	ISO	RGD:1345686	6480464	Copper analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:12432545 more ...
copper(2+)	multiple interactions	ISO	RGD:1345686	6480464	[NSC 689534 binds to Copper] which results in increased expression of CXCL8 mRNA more ...	CTD	PMID:12432545 more ...
copper(2+)	increases expression	ISO	RGD:1345686	6480464	Copper analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:12432545 more ...
copper(2+)	increases secretion	ISO	RGD:1345686	6480464	Copper results in increased secretion of CXCL8 protein	CTD	PMID:22981796
copper(II) chloride	increases secretion	ISO	RGD:1345686	6480464	cupric chloride results in increased secretion of CXCL8 protein	CTD	PMID:12865660
copper(II) chloride	increases expression	ISO	RGD:1345686	6480464	cupric chloride results in increased expression of CXCL8 mRNA, cupric chloride results in increased expression of CXCL8 protein	CTD	PMID:12865660 more ...
copper(II) sulfate	increases expression	ISO	RGD:1345686	6480464	Copper Sulfate results in increased expression of CXCL8 mRNA, Copper Sulfate results in increased expression of CXCL8 protein	CTD	PMID:19549813, PMID:26456670
copper(II) sulfate	increases secretion	ISO	RGD:1345686	6480464	Copper Sulfate results in increased secretion of CXCL8 protein	CTD	PMID:16099135, PMID:23692033
copper(II) sulfate	multiple interactions	ISO	RGD:1345686	6480464	Copper Sulfate promotes the reaction [Homocysteine results in increased expression of CXCL8 mRNA], TLR4 protein inhibits the reaction [Copper Sulfate results in increased secretion of CXCL8 protein]	CTD	PMID:12964812, PMID:23692033
cortisol	decreases secretion	ISO	RGD:1345686	6480464	Hydrocortisone results in decreased secretion of CXCL8 protein	CTD	PMID:29935159
cortisol	multiple interactions	ISO	RGD:1345686	6480464	[Catechin co-treated with tert-Butylhydroperoxide co-treated with Hydrocortisone] results in decreased secretion of CXCL8 protein more ...	CTD	PMID:26481333 more ...
cortisol	decreases response to substance	ISO	RGD:1345686	6480464	Hydrocortisone results in decreased susceptibility to CXCL8 protein	CTD	PMID:7522859
crocidolite asbestos	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:15952644 more ...
crocidolite asbestos	increases secretion	ISO	RGD:1345686	6480464	Asbestos, Crocidolite results in increased secretion of CXCL8 protein	CTD	PMID:16272461 more ...
crocidolite asbestos	decreases expression	ISO	RGD:1345686	6480464	Asbestos, Crocidolite results in decreased expression of CXCL8 mRNA alternative form	CTD	PMID:20831825
crocidolite asbestos	increases expression	ISO	RGD:1345686	6480464	Asbestos, Crocidolite results in increased expression of CXCL8 mRNA, Asbestos, Crocidolite results in increased expression of CXCL8 protein	CTD	PMID:15952644 more ...
crotonaldehyde	affects secretion	ISO	RGD:1345686	6480464	2-butenal affects the secretion of CXCL8 protein	CTD	PMID:28947239
crotonaldehyde	decreases expression	ISO	RGD:1345686	6480464	2-butenal results in decreased expression of CXCL8 mRNA	CTD	PMID:20471460
CU-O LINKAGE	increases secretion	ISO	RGD:1345686	6480464	cupric oxide results in increased secretion of CXCL8 protein	CTD	PMID:23906720
CU-O LINKAGE	affects expression	ISO	RGD:1345686	6480464	cupric oxide affects the expression of CXCL8 mRNA	CTD	PMID:28705761
curcumin	multiple interactions	ISO	RGD:1345686	6480464	Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12216086 more ...
curcumin	decreases expression	ISO	RGD:1345686	6480464	Curcumin results in decreased expression of CXCL8 protein	CTD	PMID:18226269
cyanuric chloride	increases expression	ISO	RGD:1345686	6480464	cyanuric chloride results in increased expression of CXCL8 mRNA	CTD	PMID:20713136
cycloheximide	multiple interactions	ISO	RGD:1345686	6480464	[TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein more ...	CTD	PMID:12812920 more ...
cycloheximide	increases expression	ISO	RGD:1345686	6480464	Cycloheximide results in increased expression of CXCL8 mRNA	CTD	PMID:21146893
cyclophosphamide	increases expression	ISO	RGD:1345686	6480464	Cyclophosphamide results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
cyclosporin A	multiple interactions	ISO	RGD:1345686	6480464	Cyclosporine inhibits the reaction [Histamine results in increased expression of CXCL8 mRNA]	CTD	PMID:9609743
cyclosporin A	increases expression	ISO	RGD:1345686	6480464	Cyclosporine results in increased expression of CXCL8 mRNA	CTD	PMID:20106945 more ...
cyclosporin A	decreases expression	ISO	RGD:1345686	6480464	Cyclosporine results in decreased expression of CXCL8 mRNA, Cyclosporine results in decreased expression of CXCL8 protein	CTD	PMID:15286717 more ...
cytochalasin D	multiple interactions	ISO	RGD:1345686	6480464	Cytochalasin D inhibits the reaction [Particulate Matter results in increased expression of CXCL8 protein] more ...	CTD	PMID:11145710 more ...
cytochalasin D	increases stability	ISO	RGD:1345686	6480464	Cytochalasin D results in increased stability of CXCL8 mRNA	CTD	PMID:16499908
D-glucosamine	multiple interactions	ISO	RGD:1345686	6480464	Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18026701 more ...
D-glucose	increases expression	ISO	RGD:1345686	6480464	Glucose results in increased expression of CXCL8 mRNA, Glucose results in increased expression of CXCL8 protein	CTD	PMID:20578705 more ...
D-glucose	increases secretion	ISO	RGD:1345686	6480464	Glucose results in increased secretion of CXCL8 protein	CTD	PMID:17665966
D-glucose	multiple interactions	ISO	RGD:1345686	6480464	aspalathin inhibits the reaction [Glucose results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:17665966 more ...
dacarbazine	increases secretion	ISO	RGD:1345686	6480464	Dacarbazine results in increased secretion of CXCL8 protein	CTD	PMID:12939465, PMID:15026559
dacarbazine	decreases response to substance	ISO	RGD:1345686	6480464	CXCL8 protein results in decreased susceptibility to Dacarbazine	CTD	PMID:12939465 more ...
dacarbazine	increases expression	ISO	RGD:1345686	6480464	Dacarbazine results in increased expression of CXCL8 mRNA, Dacarbazine results in increased expression of CXCL8 protein	CTD	PMID:12939465 more ...
daidzein	multiple interactions	ISO	RGD:1345686	6480464	daidzein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA]	CTD	PMID:21056929
daidzein	decreases expression	ISO	RGD:1345686	6480464	daidzein results in decreased expression of CXCL8 mRNA	CTD	PMID:21056929
danazol	multiple interactions	ISO	RGD:1345686	6480464	Danazol inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased expression of CXCL8 mRNA], Danazol inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased expression of CXCL8 protein]	CTD	PMID:15866594
dapsone	multiple interactions	ISO	RGD:1345686	6480464	[Dapsone co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:21436242, PMID:29594315
dapsone	decreases secretion	ISO	RGD:1345686	6480464	Dapsone results in decreased secretion of CXCL8 protein	CTD	PMID:11359455
daunorubicin	decreases expression	ISO	RGD:1345686	6480464	Daunorubicin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
DDE	multiple interactions	ISO	RGD:1345686	6480464	Dichlorodiphenyl Dichloroethylene inhibits the reaction [endotoxin, Escherichia coli results in increased expression of CXCL8 protein]	CTD	PMID:28412309
DDT	multiple interactions	ISO	RGD:1345686	6480464	DDT inhibits the reaction [endotoxin, Escherichia coli results in increased expression of CXCL8 protein]	CTD	PMID:28412309
decane	multiple interactions	ISO	RGD:1345686	6480464	decane results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:19720135
Deguelin	multiple interactions	ISO	RGD:1345686	6480464	deguelin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]	CTD	PMID:22623043
dehydroepiandrosterone	multiple interactions	ISO	RGD:1345686	6480464	[Lipopolysaccharides co-treated with Dehydroepiandrosterone] results in increased secretion of CXCL8 protein, Flutamide inhibits the reaction [[Lipopolysaccharides co-treated with Dehydroepiandrosterone] results in increased secretion of CXCL8 protein]	CTD	PMID:27239218
deoxynivalenol	multiple interactions	ISO	RGD:1345686	6480464	15-deoxy-delta(12 more ...	CTD	PMID:16364386 more ...
deoxynivalenol	increases secretion	ISO	RGD:1345686	6480464	deoxynivalenol results in increased secretion of CXCL8 protein	CTD	PMID:20633634, PMID:23792671
deoxynivalenol	increases expression	ISO	RGD:1345686	6480464	[deoxynivalenol results in increased expression of EGR1 protein] which results in increased expression of CXCL8 protein more ...	CTD	PMID:16364386 more ...
deoxynivalenol	decreases degradation	ISO	RGD:1345686	6480464	deoxynivalenol results in decreased degradation of CXCL8 mRNA	CTD	PMID:18485432
dequalinium	decreases expression	ISO	RGD:1345686	6480464	Dequalinium results in decreased expression of CXCL8 protein	CTD	PMID:20116850
desferrioxamine B	multiple interactions	ISO	RGD:1345686	6480464	Deferoxamine inhibits the reaction [Coal Ash results in increased expression of CXCL8 protein] more ...	CTD	PMID:17097691 more ...
desferrioxamine B	increases expression	ISO	RGD:1345686	6480464	Deferoxamine results in increased expression of CXCL8 mRNA	CTD	PMID:17097691
desferrioxamine B	increases secretion	ISO	RGD:1345686	6480464	Deferoxamine results in increased secretion of CXCL8 protein	CTD	PMID:17097691
desloratadine	multiple interactions	ISO	RGD:1345686	6480464	[montelukast co-treated with desloratadine] results in decreased expression of CXCL8 protein	CTD	PMID:15061398
dexamethasone	decreases secretion	EXP		6480464	Dexamethasone results in decreased secretion of CXCL15 protein	CTD	PMID:14694204
dexamethasone	decreases expression	ISO	RGD:1345686	6480464	Dexamethasone results in decreased expression of CXCL8 mRNA, Dexamethasone results in decreased expression of CXCL8 protein	CTD	PMID:10380089 more ...
dexamethasone	decreases expression	EXP		6480464	Dexamethasone results in decreased expression of CXCL15 protein	CTD	PMID:12504806
dexamethasone	decreases response to substance	ISO	RGD:1345686	6480464	Dexamethasone results in decreased susceptibility to CXCL8 protein	CTD	PMID:7522859
dexamethasone	multiple interactions	EXP		6480464	Dexamethasone inhibits the reaction [TNF protein results in increased expression of CXCL15 mRNA], Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of CXCL15 protein]	CTD	PMID:12504806
dexamethasone	decreases secretion	ISO	RGD:1345686	6480464	Dexamethasone results in decreased secretion of CXCL8 protein	CTD	PMID:17235257, PMID:21436242
dexamethasone	multiple interactions	ISO	RGD:1345686	6480464	[Dexamethasone co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:12070353 more ...
dextran sulfate	increases expression	EXP		6480464	Dextran Sulfate results in increased expression of CXCL15 protein	CTD	PMID:20637373
diazepam	multiple interactions	ISO	RGD:1345686	6480464	Diazepam inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased expression of CXCL8 mRNA], Diazepam inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased expression of CXCL8 protein]	CTD	PMID:23266380
diazinon	decreases expression	ISO	RGD:1345686	6480464	Diazinon results in decreased expression of CXCL8 mRNA	CTD	PMID:19589100
diazinon	multiple interactions	ISO	RGD:1345686	6480464	[TNF protein co-treated with Diazinon] results in decreased expression of CXCL8 mRNA	CTD	PMID:19589100
dibenziodolium	multiple interactions	ISO	RGD:1345686	6480464	diphenyleneiodonium inhibits the reaction [acetylleucyl-leucyl-norleucinal results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12208513 more ...
dibutyl phthalate	multiple interactions	ISO	RGD:1345686	6480464	[Dibutyl Phthalate co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA, Dibutyl Phthalate results in increased expression of and results in increased secretion of CXCL8	CTD	PMID:22723514, PMID:29594315
dibutyl phthalate	increases expression	ISO	RGD:1345686	6480464	Dibutyl Phthalate results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
dichloromethane	multiple interactions	ISO	RGD:1345686	6480464	[Particulate Matter co-treated with Methylene Chloride] results in increased expression of CXCL8 mRNA, carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of CXCL8 mRNA]	CTD	PMID:30503853
dichloromethane	increases expression	ISO	RGD:1345686	6480464	Methylene Chloride results in increased expression of CXCL8 mRNA	CTD	PMID:20359517
dichromium trioxide	increases secretion	ISO	RGD:1345686	6480464	chromic oxide analog results in increased secretion of CXCL8 protein	CTD	PMID:24885771
diclofenac	multiple interactions	ISO	RGD:1345686	6480464	Diclofenac inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:24104198, PMID:27313093
diclofenac	affects expression	ISO	RGD:1345686	6480464	Diclofenac affects the expression of CXCL8 mRNA	CTD	PMID:24752500
diclofenac	decreases expression	ISO	RGD:1345686	6480464	Diclofenac results in decreased expression of CXCL8 mRNA, Diclofenac results in decreased expression of CXCL8 protein	CTD	PMID:19192274
diclofenac	increases secretion	ISO	RGD:1345686	6480464	Diclofenac analog results in increased secretion of CXCL8 protein	CTD	PMID:24104198
diclofenac	increases expression	ISO	RGD:1345686	6480464	Diclofenac analog results in increased expression of CXCL8 mRNA, Diclofenac results in increased expression of CXCL8 mRNA	CTD	PMID:17379860, PMID:24104198
dicoumarol	multiple interactions	ISO	RGD:1345686	6480464	Dicumarol inhibits the reaction [Ozone results in increased expression of CXCL8 mRNA]	CTD	PMID:19059883
dienogest	multiple interactions	ISO	RGD:1345686	6480464	dienogest inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:15866594, PMID:22014880
diethanolamine	increases expression	ISO	RGD:1345686	6480464	diethanolamine results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
diethyl maleate	increases stability	ISO	RGD:1345686	6480464	diethyl maleate results in increased stability of CXCL8 mRNA	CTD	PMID:21969073
diethyl maleate	multiple interactions	ISO	RGD:1345686	6480464	bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CXCL8 protein]	CTD	PMID:24136171
diethyl maleate	increases expression	ISO	RGD:1345686	6480464	diethyl maleate results in increased expression of CXCL8 mRNA, diethyl maleate results in increased expression of CXCL8 protein	CTD	PMID:20491607 more ...
diethyl maleate	increases secretion	ISO	RGD:1345686	6480464	diethyl maleate results in increased secretion of CXCL8 protein	CTD	PMID:20541004, PMID:21969073
diethyl phthalate	increases expression	ISO	RGD:1345686	6480464	diethyl phthalate results in increased expression of CXCL8 mRNA	CTD	PMID:21920952, PMID:23724284
digitoxigenin	decreases expression	ISO	RGD:1345686	6480464	Digitoxigenin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
digitoxin	decreases secretion	ISO	RGD:1345686	6480464	Digitoxin results in decreased secretion of CXCL8 protein	CTD	PMID:15136726
digoxigenin	decreases expression	ISO	RGD:1345686	6480464	Digoxigenin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
digoxin	increases expression	ISO	RGD:1345686	6480464	Digoxin results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
digoxin	decreases expression	ISO	RGD:1345686	6480464	Digoxin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
dimethoate	increases secretion	ISO	RGD:1345686	6480464	Dimethoate results in increased secretion of CXCL8 protein	CTD	PMID:23994500
dimethyl sulfoxide	multiple interactions	ISO	RGD:1345686	6480464	[Dimethyl Sulfoxide co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA, Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]	CTD	PMID:17529908, PMID:29594315
dimethyl sulfoxide	decreases expression	ISO	RGD:1345686	6480464	Dimethyl Sulfoxide results in decreased expression of CXCL8 mRNA	CTD	PMID:24296301
dimethyl sulfoxide	increases expression	ISO	RGD:1345686	6480464	Dimethyl Sulfoxide results in increased expression of CXCL8 mRNA	CTD	PMID:18684396
dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium	increases expression	ISO	RGD:1345686	6480464	Benzethonium results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium	decreases expression	ISO	RGD:1345686	6480464	Benzethonium results in decreased expression of CXCL8 protein	CTD	PMID:20116850
dimethylarsinous acid	increases expression	ISO	RGD:1345686	6480464	dimethylarsinous acid results in increased expression of CXCL8 mRNA	CTD	PMID:23876855, PMID:24140498
dimethylarsinous acid	multiple interactions	ISO	RGD:1345686	6480464	Lipopolysaccharides promotes the reaction [dimethylarsinous acid results in increased secretion of CXCL8 protein]	CTD	PMID:24140498
dimethylarsinous acid	increases secretion	ISO	RGD:1345686	6480464	dimethylarsinous acid results in increased secretion of CXCL8 protein	CTD	PMID:24140498
dinitrogen	multiple interactions	ISO	RGD:1345686	6480464	[Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CXCL8 protein	CTD	PMID:30711708
dioxygen	multiple interactions	ISO	RGD:1345686	6480464	3 more ...	CTD	PMID:22535156, PMID:23452621
dioxygen	increases expression	ISO	RGD:1345686	6480464	Oxygen deficiency results in increased expression of CXCL8 mRNA, Oxygen results in increased expression of CXCL8 mRNA	CTD	PMID:23452621 more ...
diphenhydramine	multiple interactions	ISO	RGD:1345686	6480464	Diphenhydramine inhibits the reaction [Histamine results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:11336536 more ...
diphenhydramine	decreases response to substance	ISO	RGD:1345686	6480464	Diphenhydramine results in decreased susceptibility to CXCL8 protein	CTD	PMID:7522859
diphenylmethane-4,4'-diisocyanate	multiple interactions	ISO	RGD:1345686	6480464	SB 203580 affects the reaction [4, 4'-diphenylmethane diisocyanate results in increased secretion of CXCL8 protein]	CTD	PMID:18494145
diphenylmethane-4,4'-diisocyanate	increases secretion	ISO	RGD:1345686	6480464	4, 4'-diphenylmethane diisocyanate results in increased secretion of CXCL8 protein	CTD	PMID:18494145
divanadium pentaoxide	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [vanadium pentoxide results in increased expression of CXCL8 protein], tetramethylthiourea inhibits the reaction [vanadium pentoxide results in increased expression of CXCL8 protein]	CTD	PMID:9707512
divanadium pentaoxide	increases expression	ISO	RGD:1345686	6480464	vanadium pentoxide results in increased expression of CXCL8 mRNA, vanadium pentoxide results in increased expression of CXCL8 protein	CTD	PMID:17459161, PMID:9707512
dobutamine	multiple interactions	ISO	RGD:1345686	6480464	Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein], Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]	CTD	PMID:12818968, PMID:15502056
dodecan-1-ol	increases expression	ISO	RGD:1345686	6480464	Dodecanol analog results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
dodecane	multiple interactions	ISO	RGD:1345686	6480464	n-dodecane results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:19720135
dodecanoic acid	multiple interactions	ISO	RGD:1345686	6480464	Curcumin inhibits the reaction [lauric acid results in increased expression of and results in increased secretion of CXCL8 protein] more ...	CTD	PMID:18413660
doramapimod	multiple interactions	ISO	RGD:1345686	6480464	BIRB 796 inhibits the reaction [Dinitrofluorobenzene results in increased secretion of CXCL8 protein], BIRB 796 inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:14997032, PMID:19427879
doxorubicin	decreases expression	ISO	RGD:1345686	6480464	Doxorubicin results in decreased expression of CXCL8 mRNA	CTD	PMID:15899819, PMID:29803840
doxorubicin	increases expression	ISO	RGD:1345686	6480464	Doxorubicin results in increased expression of CXCL8 mRNA	CTD	PMID:18510171
doxorubicin	affects response to substance	ISO	RGD:1345686	6480464	CXCL8 protein affects the susceptibility to Doxorubicin	CTD	PMID:16217747
doxorubicin	multiple interactions	ISO	RGD:1345686	6480464	Doxorubicin results in increased expression of and results in increased secretion of CXCL8 protein, TNF protein inhibits the reaction [Doxorubicin results in decreased expression of CXCL8 mRNA]	CTD	PMID:12908082 more ...
doxycycline	multiple interactions	ISO	RGD:1345686	6480464	Doxycycline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of CXCL8 protein]	CTD	PMID:16134060
ebselen	multiple interactions	ISO	RGD:1345686	6480464	ebselen inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:14572605
efavirenz	increases secretion	ISO	RGD:1345686	6480464	efavirenz results in increased secretion of CXCL8 protein	CTD	PMID:21619898
elemental selenium	increases expression	ISO	RGD:1345686	6480464	Selenium results in increased expression of CXCL8 mRNA	CTD	PMID:17293063
elesclomol	increases expression	ISO	RGD:1345686	6480464	elesclomol results in increased expression of CXCL8 mRNA	CTD	PMID:18723479
ellagic acid	multiple interactions	ISO	RGD:1345686	6480464	Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]	CTD	PMID:18377686
embelin	decreases expression	ISO	RGD:1345686	6480464	embelin results in decreased expression of CXCL8 protein	CTD	PMID:24694877
emetine	decreases expression	ISO	RGD:1345686	6480464	Emetine results in decreased expression of CXCL8 protein	CTD	PMID:20116850
enalapril	multiple interactions	ISO	RGD:1345686	6480464	Enalapril inhibits the reaction [sodium arsenite results in increased secretion of CXCL8 protein]	CTD	PMID:28973481
endosulfan	multiple interactions	ISO	RGD:1345686	6480464	MIR22 mRNA affects the reaction [Endosulfan results in increased expression of CXCL8 mRNA]	CTD	PMID:28161397
endosulfan	increases expression	ISO	RGD:1345686	6480464	Endosulfan results in increased expression of CXCL8 mRNA	CTD	PMID:26714676 more ...
endosulfan	increases secretion	ISO	RGD:1345686	6480464	Endosulfan results in increased secretion of CXCL8 protein	CTD	PMID:26714676
enniatin	decreases expression	EXP		6480464	enniatins results in decreased expression of CXCL8 mRNA	CTD	PMID:30259633
entinostat	decreases expression	EXP		6480464	entinostat results in decreased expression of CXCL15 protein	CTD	PMID:21041383
entinostat	multiple interactions	EXP		6480464	TNFSF10 protein promotes the reaction [entinostat results in decreased expression of CXCL15 protein]	CTD	PMID:21041383
eriodictyol	multiple interactions	ISO	RGD:1345686	6480464	eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA]	CTD	PMID:20438634
erlotinib hydrochloride	decreases expression	ISO	RGD:1345686	6480464	Erlotinib Hydrochloride results in decreased expression of CXCL8 protein	CTD	PMID:23099361
erlotinib hydrochloride	increases secretion	ISO	RGD:1345686	6480464	Erlotinib Hydrochloride results in increased secretion of CXCL8 protein	CTD	PMID:27738319
erlotinib hydrochloride	multiple interactions	ISO	RGD:1345686	6480464	[Erlotinib Hydrochloride results in decreased susceptibility to Erlotinib Hydrochloride] which results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:27738319, PMID:28101945
erythromycin A	multiple interactions	ISO	RGD:1345686	6480464	Erythromycin inhibits the reaction [Particulate Matter results in increased expression of CXCL8 mRNA]	CTD	PMID:23291319
ethanol	multiple interactions	EXP		6480464	5 more ...	CTD	PMID:29476730
ethanol	increases secretion	ISO	RGD:1345686	6480464	Ethanol results in increased secretion of CXCL8 protein, Ethanol results in increased secretion of IL8 protein	CTD	PMID:23300006, PMID:28013186
ethanol	multiple interactions	ISO	RGD:1345686	6480464	Ethanol inhibits the reaction [sodium arsenite results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18182400, PMID:28013186
ethanol	increases expression	EXP		6480464	Ethanol results in increased expression of CXCL15 protein	CTD	PMID:29476730
ethylbenzene	increases expression	ISO	RGD:1345686	6480464	ethylbenzene results in increased expression of CXCL8 mRNA	CTD	PMID:20359517
ethylene glycol bis(2-aminoethyl)tetraacetic acid	multiple interactions	ISO	RGD:1345686	6480464	Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of CXCL8 mRNA]	CTD	PMID:16173059
ethylenediamine	increases expression	ISO	RGD:1345686	6480464	ethylenediamine results in increased expression of CXCL8 mRNA	CTD	PMID:21920952, PMID:27965148
ethylenediamine	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [ethylenediamine results in increased expression of CXCL8 mRNA]	CTD	PMID:21920952
ethylenediaminetetraacetic acid	multiple interactions	ISO	RGD:1345686	6480464	Edetic Acid inhibits the reaction [Cadmium results in increased expression of CXCL8 protein]	CTD	PMID:8123758
ethylisopropylamiloride	multiple interactions	ISO	RGD:1345686	6480464	ethylisopropylamiloride inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein], ethylisopropylamiloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 protein]	CTD	PMID:12065299, PMID:12107048
etoposide	increases expression	ISO	RGD:1345686	6480464	Etoposide results in increased expression of CXCL8 mRNA, Etoposide results in increased expression of CXCL8 protein	CTD	PMID:10540334
etoposide	multiple interactions	ISO	RGD:1345686	6480464	SB 203580 inhibits the reaction [Etoposide results in increased expression of CXCL8 protein], Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Etoposide results in increased expression of CXCL8 protein]	CTD	PMID:10540334
eugenol	increases secretion	ISO	RGD:1345686	6480464	Eugenol results in increased secretion of CXCL8 protein	CTD	PMID:30806763
eugenol	increases expression	ISO	RGD:1345686	6480464	Eugenol results in increased expression of CXCL8 mRNA, Eugenol results in increased expression of CXCL8 protein	CTD	PMID:20713136 more ...
eugenol	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [Eugenol results in increased expression of CXCL8 mRNA], Eugenol results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:21920952, PMID:23624239
farnesol	increases expression	ISO	RGD:1345686	6480464	Farnesol results in increased expression of CXCL8 mRNA	CTD	PMID:27965148, PMID:30806763
farnesol	increases secretion	ISO	RGD:1345686	6480464	Farnesol results in increased secretion of CXCL8 protein	CTD	PMID:30806763
fenbendazole	multiple interactions	ISO	RGD:1345686	6480464	U 0126 inhibits the reaction [Fenbendazole results in increased secretion of CXCL8 protein]	CTD	PMID:20848085
fenbendazole	increases expression	ISO	RGD:1345686	6480464	Fenbendazole results in increased expression of CXCL8 protein	CTD	PMID:20116850
fenbendazole	increases secretion	ISO	RGD:1345686	6480464	Fenbendazole results in increased secretion of CXCL8 protein	CTD	PMID:20848085
fenoterol	multiple interactions	ISO	RGD:1345686	6480464	Fenoterol inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of CXCL8 mRNA], Fenoterol inhibits the reaction [Tobacco Smoke Pollution analog results in increased secretion of CXCL8 protein]	CTD	PMID:22363678
ferric oxide	increases secretion	ISO	RGD:1345686	6480464	ferric oxide results in increased secretion of CXCL8 protein	CTD	PMID:24885771
ferric oxide	increases expression	ISO	RGD:1345686	6480464	ferric oxide results in increased expression of CXCL8 protein	CTD	PMID:21439359
ferrosoferric oxide	increases secretion	ISO	RGD:1345686	6480464	Ferrosoferric Oxide results in increased secretion of CXCL8 protein	CTD	PMID:24885771
ferrous oxide	increases expression	ISO	RGD:1345686	6480464	ferrous oxide results in increased expression of CXCL8 protein	CTD	PMID:21439359
fisetin	multiple interactions	ISO	RGD:1345686	6480464	fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:17884996 more ...
Flunitrazepam	multiple interactions	ISO	RGD:1345686	6480464	Flunitrazepam inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased expression of CXCL8 protein]	CTD	PMID:23266380
fluoranthene	increases secretion	ISO	RGD:1345686	6480464	fluoranthene results in increased secretion of CXCL8 protein	CTD	PMID:18434080, PMID:29787794
fluoranthene	increases expression	ISO	RGD:1345686	6480464	fluoranthene results in increased expression of CXCL8 mRNA	CTD	PMID:18434080 more ...
fluoranthene	decreases expression	ISO	RGD:1345686	6480464	fluoranthene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
fluoranthene	multiple interactions	ISO	RGD:1345686	6480464	TNF protein promotes the reaction [fluoranthene results in increased expression of CXCL8 mRNA], TNF protein promotes the reaction [fluoranthene results in increased secretion of CXCL8 protein]	CTD	PMID:18434080
flutamide	multiple interactions	ISO	RGD:1345686	6480464	Flutamide inhibits the reaction [[Lipopolysaccharides co-treated with Dehydroepiandrosterone] results in increased secretion of CXCL8 protein]	CTD	PMID:27239218
fluticasone	multiple interactions	ISO	RGD:1345686	6480464	Fluticasone inhibits the reaction [TNF protein results in increased expression of CXCL8 protein] more ...	CTD	PMID:14643170, PMID:15531761
folic acid	decreases expression	ISO	RGD:1345686	6480464	Folic Acid results in decreased expression of CXCL8 protein	CTD	PMID:16491109
folic acid	increases expression	ISO	RGD:1345686	6480464	Folic Acid deficiency results in increased expression of CXCL8 mRNA, Folic Acid deficiency results in increased expression of CXCL8 protein	CTD	PMID:24657277
folic acid	multiple interactions	ISO	RGD:1345686	6480464	[Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of CXCL8 mRNA more ...	CTD	PMID:22975265, PMID:24657277
formaldehyde	increases secretion	ISO	RGD:1345686	6480464	Formaldehyde results in increased secretion of CXCL8 protein	CTD	PMID:29860525
formaldehyde	affects expression	ISO	RGD:1345686	6480464	Formaldehyde affects the expression of CXCL8	CTD	PMID:24960057
formaldehyde	increases expression	ISO	RGD:1345686	6480464	Formaldehyde results in increased expression of CXCL8 mRNA, Formaldehyde results in increased expression of CXCL8 protein	CTD	PMID:21147603 more ...
formaldehyde	multiple interactions	EXP		6480464	[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in increased expression of CXCL15 protein	CTD	PMID:24733833
formaldehyde	decreases expression	ISO	RGD:1345686	6480464	Formaldehyde results in decreased expression of CXCL8 protein	CTD	PMID:21087659
formaldehyde	multiple interactions	ISO	RGD:1345686	6480464	[Acrolein co-treated with Formaldehyde co-treated with Ozone] results in increased expression of CXCL8 protein more ...	CTD	PMID:16860297 more ...
formononetin	multiple interactions	ISO	RGD:1345686	6480464	formononetin inhibits the reaction [CXCL8 protein results in increased phosphorylation of NFKBIA protein]	CTD	PMID:22387535
formoterol fumarate	multiple interactions	ISO	RGD:1345686	6480464	[Beclomethasone co-treated with Formoterol Fumarate] results in decreased secretion of CXCL8 protein	CTD	PMID:15679717
fragrance	increases expression	ISO	RGD:1345686	6480464	Perfume results in increased expression of CXCL8 mRNA	CTD	PMID:24768652
fulvestrant	increases expression	ISO	RGD:1345686	6480464	fulvestrant results in increased expression of CXCL8 mRNA	CTD	PMID:16298037
fulvestrant	multiple interactions	ISO	RGD:1345686	6480464	fulvestrant inhibits the reaction [2 more ...	CTD	PMID:25433332, PMID:28736254
fulvestrant	multiple interactions	EXP		6480464	fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL15 mRNA]	CTD	PMID:22553218
fumonisin B1	increases expression	ISO	RGD:1345686	6480464	fumonisin B1 results in increased expression of CXCL8 mRNA	CTD	PMID:27757495
galactose	increases expression	ISO	RGD:1345686	6480464	Galactose results in increased expression of CXCL8 mRNA	CTD	PMID:29412148
galactose	multiple interactions	ISO	RGD:1345686	6480464	ginsenoside F1 inhibits the reaction [Galactose results in increased expression of CXCL8 mRNA], ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of CXCL8 protein]	CTD	PMID:29412148
galangin	multiple interactions	ISO	RGD:1345686	6480464	galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CXCL8 mRNA]	CTD	PMID:23535185
gallic acid	multiple interactions	ISO	RGD:1345686	6480464	Gallic Acid inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA], Gallic Acid inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]	CTD	PMID:21420233
gastrin-17	increases secretion	ISO	RGD:1345686	6480464	gastrin 17 results in increased secretion of CXCL8 protein	CTD	PMID:15623601
gefitinib	multiple interactions	ISO	RGD:1345686	6480464	gefitinib inhibits the reaction [irinotecan metabolite results in increased expression of CXCL8 mRNA], gefitinib inhibits the reaction [irinotecan results in increased expression of CXCL8 mRNA]	CTD	PMID:15723263
geldanamycin	multiple interactions	ISO	RGD:1345686	6480464	geldanamycin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA], geldanamycin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]	CTD	PMID:11472980
gemcitabine	decreases expression	ISO	RGD:1345686	6480464	gemcitabine results in decreased expression of CXCL8 protein	CTD	PMID:20531411
gemcitabine	increases secretion	ISO	RGD:1345686	6480464	gemcitabine results in increased secretion of CXCL8 protein	CTD	PMID:28007550
genistein	multiple interactions	ISO	RGD:1345686	6480464	Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:15779068 more ...
genistein	increases expression	EXP		6480464	Genistein results in increased expression of CXCL15 mRNA	CTD	PMID:21810550, PMID:22553218
genistein	multiple interactions	EXP		6480464	Fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL15 mRNA]	CTD	PMID:22553218
genistein	increases expression	ISO	RGD:1345686	6480464	Genistein results in increased expression of CXCL8 mRNA	CTD	PMID:15257099
genistein	decreases expression	ISO	RGD:1345686	6480464	Genistein results in decreased expression of CXCL8 mRNA	CTD	PMID:21056929
geranial	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [citral results in increased expression of CXCL8 mRNA]	CTD	PMID:21920952
geranial	increases secretion	ISO	RGD:1345686	6480464	citral results in increased secretion of CXCL8 protein	CTD	PMID:20541004
geranial	increases expression	ISO	RGD:1345686	6480464	citral results in increased expression of CXCL8 mRNA, citral results in increased expression of CXCL8 protein	CTD	PMID:21920952 more ...
geraniol	increases expression	ISO	RGD:1345686	6480464	geraniol results in increased expression of CXCL8 mRNA	CTD	PMID:20713136, PMID:21920952
geraniol	increases secretion	ISO	RGD:1345686	6480464	geraniol results in increased secretion of CXCL8 protein	CTD	PMID:30806763
ginsenoside C-K	multiple interactions	ISO	RGD:1345686	6480464	ginsenoside M1 inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]	CTD	PMID:21875580
ginsenoside F1	multiple interactions	ISO	RGD:1345686	6480464	ginsenoside F1 inhibits the reaction [Galactose results in increased expression of CXCL8 mRNA], ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of CXCL8 protein]	CTD	PMID:29412148
gliotoxin	multiple interactions	ISO	RGD:1345686	6480464	Gliotoxin inhibits the reaction [Zymosan results in increased expression of CXCL8 mRNA]	CTD	PMID:11527995
glucose	increases expression	ISO	RGD:1345686	6480464	Glucose results in increased expression of CXCL8 mRNA, Glucose results in increased expression of CXCL8 protein	CTD	PMID:20578705 more ...
glucose	increases secretion	ISO	RGD:1345686	6480464	Glucose results in increased secretion of CXCL8 protein	CTD	PMID:17665966
glucose	multiple interactions	ISO	RGD:1345686	6480464	aspalathin inhibits the reaction [Glucose results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:17665966 more ...
glutaraldehyde	affects expression	ISO	RGD:1345686	6480464	Glutaral affects the expression of CXCL8 mRNA	CTD	PMID:20200221
glutaraldehyde	increases expression	ISO	RGD:1345686	6480464	Glutaral results in increased expression of CXCL8 mRNA	CTD	PMID:20713136
glutathione	decreases abundance	ISO	RGD:1345686	6480464	CXCL8 protein results in decreased abundance of Glutathione	CTD	PMID:28238931
glutathione	decreases expression	ISO	RGD:1345686	6480464	Glutathione results in decreased expression of CXCL8 mRNA	CTD	PMID:22385246
glutathione	multiple interactions	ISO	RGD:1345686	6480464	Benzo(a)pyrene promotes the reaction [CXCL8 protein results in decreased abundance of Glutathione] more ...	CTD	PMID:10919993 more ...
glutathione disulfide	multiple interactions	ISO	RGD:1345686	6480464	[Benzo(a)pyrene co-treated with CXCL8 protein] results in increased abundance of Glutathione Disulfide	CTD	PMID:28238931
glycerol	multiple interactions	ISO	RGD:1345686	6480464	Glycerol results in decreased expression of and results in decreased secretion of CXCL8 protein	CTD	PMID:29953848
glycyrrhetinate	multiple interactions	EXP		6480464	18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL15 protein]	CTD	PMID:21644799
glycyrrhetinic acid	multiple interactions	EXP		6480464	18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL15 protein]	CTD	PMID:21644799
glycyrrhizinic acid	multiple interactions	ISO	RGD:1345686	6480464	Glycyrrhizic Acid inhibits the reaction [Histamine results in increased expression of CXCL8 mRNA], Glycyrrhizic Acid inhibits the reaction [Histamine results in increased secretion of CXCL8 protein]	CTD	PMID:29452068
glycyrrhizinic acid	multiple interactions	EXP		6480464	Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL15 protein]	CTD	PMID:21644799
glyoxal	affects expression	ISO	RGD:1345686	6480464	Glyoxal analog affects the expression of CXCL8 mRNA	CTD	PMID:20200221
glyoxal	increases expression	ISO	RGD:1345686	6480464	Glyoxal results in increased expression of CXCL8 mRNA	CTD	PMID:21920952, PMID:27965148
graphite	multiple interactions	ISO	RGD:1345686	6480464	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 protein] more ...	CTD	PMID:25446327
GW 3965	increases expression	ISO	RGD:1345686	6480464	GW 3965 results in increased expression of CXCL8 mRNA	CTD	PMID:19426978
harmaline	multiple interactions	ISO	RGD:1345686	6480464	Harmaline inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein], Harmaline inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 protein]	CTD	PMID:12065299, PMID:12107048
helenalin	multiple interactions	ISO	RGD:1345686	6480464	helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]	CTD	PMID:23688403
heparin	increases secretion	ISO	RGD:1345686	6480464	Heparin analog results in increased secretion of CXCL8 protein, Heparin results in increased secretion of CXCL8 protein	CTD	PMID:26476401, PMID:8595612
hesperidin	multiple interactions	ISO	RGD:1345686	6480464	Hesperidin inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein], Hesperidin inhibits the reaction [TNF protein co-treated with and results in increased expression of IL1B protein co-treated with and results in increased expression of CXCL8 protein]	CTD	PMID:17400256
hexadecane	multiple interactions	ISO	RGD:1345686	6480464	n-hexadecane results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:19720135
hexadecanoic acid	multiple interactions	ISO	RGD:1345686	6480464	[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:21745629, PMID:30547786
hexadecanoic acid	increases expression	ISO	RGD:1345686	6480464	Palmitic Acid results in increased expression of CXCL8 mRNA	CTD	PMID:21745629
hexanal	affects secretion	ISO	RGD:1345686	6480464	n-hexanal affects the secretion of CXCL8 protein	CTD	PMID:28947239
hexane	multiple interactions	ISO	RGD:1345686	6480464	[Particulate Matter co-treated with n-hexane] results in increased expression of CXCL8 mRNA	CTD	PMID:30503853
histamine	multiple interactions	ISO	RGD:1345686	6480464	[Histamine co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:10051702 more ...
histamine	increases secretion	ISO	RGD:1345686	6480464	Histamine results in increased secretion of CXCL8 protein	CTD	PMID:10051702, PMID:29452068
histamine	increases expression	ISO	RGD:1345686	6480464	Histamine results in increased expression of CXCL8 mRNA, Histamine results in increased expression of CXCL8 protein	CTD	PMID:11336536 more ...
homocysteine	increases expression	ISO	RGD:1345686	6480464	Homocysteine results in increased expression of CXCL8 mRNA, Homocysteine results in increased expression of CXCL8 protein	CTD	PMID:12964812
homocysteine	multiple interactions	ISO	RGD:1345686	6480464	[Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12964812 more ...
homocysteine	increases secretion	ISO	RGD:1345686	6480464	Homocysteine results in increased secretion of CXCL8 protein	CTD	PMID:16715183
hyaluronic acid	multiple interactions	ISO	RGD:1345686	6480464	[acetic anhydride results in increased acetylation of Hyaluronic Acid metabolite] which results in increased secretion of CXCL8 protein more ...	CTD	PMID:25053413
hydrogen chloride	decreases expression	ISO	RGD:1345686	6480464	Hydrochloric Acid results in decreased expression of CXCL8 mRNA	CTD	PMID:15046208
hydrogen peroxide	increases expression	ISO	RGD:1345686	6480464	Hydrogen Peroxide results in increased expression of CXCL8 more ...	CTD	PMID:12207893 more ...
hydrogen peroxide	affects expression	ISO	RGD:1345686	6480464	Hydrogen Peroxide affects the expression of CXCL8 mRNA	CTD	PMID:23410634
hydrogen peroxide	increases secretion	ISO	RGD:1345686	6480464	Hydrogen Peroxide results in increased secretion of CXCL8 protein	CTD	PMID:19706323 more ...
hydrogen peroxide	multiple interactions	ISO	RGD:1345686	6480464	(+)-JQ1 compound inhibits the reaction [[Hydrogen Peroxide co-treated with IL1B protein] promotes the reaction [BRD4 protein binds to CXCL8 promoter]] more ...	CTD	PMID:12207893 more ...
hydroquinone	increases expression	ISO	RGD:1345686	6480464	hydroquinone results in increased expression of CXCL8 protein	CTD	PMID:15356918, PMID:17572062
hydroquinone	decreases secretion	ISO	RGD:1345686	6480464	hydroquinone results in decreased secretion of CXCL8 protein	CTD	PMID:22302391
hydroquinone	increases secretion	ISO	RGD:1345686	6480464	hydroquinone results in increased secretion of CXCL8 protein	CTD	PMID:17118622, PMID:20946948
hydroxychloroquine	increases expression	ISO	RGD:1345686	6480464	Hydroxychloroquine results in increased expression of CXCL8 mRNA	CTD	PMID:15139008
hydroxycitronellal	increases secretion	ISO	RGD:1345686	6480464	hydroxycitronellal results in increased secretion of CXCL8 protein	CTD	PMID:17118622
hyperforin	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hyperforin results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:15622447
hyperforin	increases secretion	ISO	RGD:1345686	6480464	hyperforin results in increased secretion of CXCL8 protein	CTD	PMID:15622447
hyperforin	increases expression	ISO	RGD:1345686	6480464	hyperforin results in increased expression of CXCL8 mRNA	CTD	PMID:15622447
ibufenac	increases expression	ISO	RGD:1345686	6480464	ibufenac metabolite results in increased expression of CXCL8 mRNA	CTD	PMID:26528891
ICI 118551	multiple interactions	ISO	RGD:1345686	6480464	ICI 118551 inhibits the reaction [1-nitropyrene results in increased secretion of CXCL8 protein]	CTD	PMID:24904980
imidurea	increases expression	ISO	RGD:1345686	6480464	imidazolidinyl urea results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
imidurea	increases secretion	ISO	RGD:1345686	6480464	imidazolidinyl urea results in increased secretion of CXCL8 protein	CTD	PMID:20541004
indometacin	decreases expression	ISO	RGD:1345686	6480464	Indomethacin results in decreased expression of CXCL8 mRNA	CTD	PMID:16984733
indometacin	multiple interactions	ISO	RGD:1345686	6480464	[Indomethacin co-treated with isoeugenol] results in increased expression of CXCL8 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CXCL8 mRNA	CTD	PMID:21284934, PMID:28628672
iohexol	decreases expression	ISO	RGD:1345686	6480464	Iohexol results in decreased expression of CXCL8 mRNA	CTD	PMID:29705293
ionomycin	multiple interactions	ISO	RGD:1345686	6480464	[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein more ...	CTD	PMID:17000667 more ...
iopamidol	decreases expression	ISO	RGD:1345686	6480464	Iopamidol results in decreased expression of CXCL8 mRNA	CTD	PMID:29705293
irinotecan	increases expression	ISO	RGD:1345686	6480464	Irinotecan metabolite results in increased expression of CXCL8 mRNA, Irinotecan results in increased expression of CXCL8 mRNA	CTD	PMID:15723263
irinotecan	multiple interactions	ISO	RGD:1345686	6480464	Gefitinib inhibits the reaction [Irinotecan metabolite results in increased expression of CXCL8 mRNA], Gefitinib inhibits the reaction [Irinotecan results in increased expression of CXCL8 mRNA]	CTD	PMID:15723263
iron atom	increases secretion	EXP		6480464	Iron results in increased secretion of CXCL15 protein	CTD	PMID:26416317
iron atom	increases expression	ISO	RGD:1345686	6480464	Iron analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
iron atom	multiple interactions	ISO	RGD:1345686	6480464	Iron inhibits the reaction [Asbestos, Amphibole results in increased expression of CXCL8]	CTD	PMID:21605006
iron trichloride	multiple interactions	ISO	RGD:1345686	6480464	ferric chloride inhibits the reaction [nickel sulfate results in increased expression of CXCL8 protein]	CTD	PMID:15081272
iron(0)	increases secretion	EXP		6480464	Iron results in increased secretion of CXCL15 protein	CTD	PMID:26416317
iron(0)	increases expression	ISO	RGD:1345686	6480464	Iron analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
iron(0)	multiple interactions	ISO	RGD:1345686	6480464	Iron inhibits the reaction [Asbestos, Amphibole results in increased expression of CXCL8]	CTD	PMID:21605006
iron(2+) sulfate (anhydrous)	multiple interactions	ISO	RGD:1345686	6480464	ferrous sulfate inhibits the reaction [nickel sulfate results in increased expression of CXCL8 protein], N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [ferrous sulfate results in increased expression of CXCL8 mRNA]	CTD	PMID:15081272, PMID:21540303
iron(2+) sulfate (anhydrous)	increases expression	ISO	RGD:1345686	6480464	ferrous sulfate results in increased expression of CXCL8 mRNA	CTD	PMID:19428942, PMID:21540303
isocyanates	increases expression	ISO	RGD:1345686	6480464	Isocyanates analog results in increased expression of CXCL8 protein	CTD	PMID:19111005
isoeugenol	multiple interactions	ISO	RGD:1345686	6480464	[Indomethacin co-treated with isoeugenol] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:21284934, PMID:21969073
isoeugenol	increases expression	ISO	RGD:1345686	6480464	isoeugenol results in increased expression of CXCL8 mRNA, isoeugenol results in increased expression of CXCL8 protein	CTD	PMID:21284934 more ...
isoflavones	multiple interactions	ISO	RGD:1345686	6480464	Isoflavones inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA], Isoflavones inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]	CTD	PMID:19926933
isoflavones	decreases expression	ISO	RGD:1345686	6480464	Isoflavones results in decreased expression of CXCL8 mRNA	CTD	PMID:16365062
isoniazide	multiple interactions	ISO	RGD:1345686	6480464	[Isoniazid co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
isophorone diisocyanate	increases expression	ISO	RGD:1345686	6480464	isophorone diisocyanate results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
isophorone diisocyanate	multiple interactions	ISO	RGD:1345686	6480464	[isophorone diisocyanate co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
isoprenaline	multiple interactions	ISO	RGD:1345686	6480464	Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA], Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:21088047, PMID:9258252
itraconazole	multiple interactions	ISO	RGD:1345686	6480464	Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]	CTD	PMID:23688403
ivermectin	decreases expression	ISO	RGD:1345686	6480464	Ivermectin results in decreased expression of CXCL8 mRNA, Ivermectin results in decreased expression of CXCL8 protein	CTD	PMID:28653460
ivermectin	multiple interactions	ISO	RGD:1345686	6480464	[Ivermectin co-treated with Albendazole] results in increased expression of CXCL8 protein	CTD	PMID:16861626
kaempferol	multiple interactions	ISO	RGD:1345686	6480464	kaempferol inhibits the reaction [IL32 protein results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:20438634, PMID:28711657
ketanserin	multiple interactions	ISO	RGD:1345686	6480464	Ketanserin inhibits the reaction [Tobacco Smoke Pollution results in increased secretion of CXCL8 protein]	CTD	PMID:22048642
ketoconazole	multiple interactions	ISO	RGD:1345686	6480464	AHR protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]] more ...	CTD	PMID:21753779 more ...
KN-93	multiple interactions	ISO	RGD:1345686	6480464	KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA]	CTD	PMID:18089838
KT 5720	multiple interactions	ISO	RGD:1345686	6480464	KT 5720 inhibits the reaction [Deferoxamine results in increased expression of CXCL8 protein], KT 5720 inhibits the reaction [isoeugenol results in increased expression of CXCL8 mRNA]	CTD	PMID:17097691, PMID:21969073
L-ascorbic acid	multiple interactions	ISO	RGD:1345686	6480464	[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein] more ...	CTD	PMID:16715183, PMID:25551565
L-ascorbic acid	affects expression	ISO	RGD:1345686	6480464	Ascorbic Acid affects the expression of CXCL8 mRNA, Ascorbic Acid deficiency affects the expression of CXCL8 mRNA	CTD	PMID:19932582
L-cystathionine	multiple interactions	ISO	RGD:1345686	6480464	Cystathionine inhibits the reaction [Formaldehyde results in increased expression of CXCL8 protein]	CTD	PMID:27664576
L-cysteine	multiple interactions	ISO	RGD:1345686	6480464	Cysteine inhibits the reaction [Formaldehyde results in increased expression of CXCL8 protein]	CTD	PMID:27664576
L-selenocysteine	multiple interactions	ISO	RGD:1345686	6480464	Selenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:14572605
lactacystin	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [lactacystin results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12208513
lactacystin	increases expression	ISO	RGD:1345686	6480464	lactacystin results in increased expression of CXCL8 mRNA	CTD	PMID:12208513
lanatoside C	decreases expression	ISO	RGD:1345686	6480464	lanatoside C results in decreased expression of CXCL8 protein	CTD	PMID:20116850
lansoprazole	decreases expression	ISO	RGD:1345686	6480464	Lansoprazole results in decreased expression of CXCL8 mRNA, Lansoprazole results in decreased expression of CXCL8 protein	CTD	PMID:15089887, PMID:15513378
lead diacetate	multiple interactions	EXP		6480464	[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with U 0126] inhibits the reaction [lead acetate results in increased secretion of CXCL15 protein]	CTD	PMID:24530660
lead diacetate	increases secretion	ISO	RGD:1345686	6480464	lead acetate results in increased secretion of CXCL8 protein	CTD	PMID:22839698
lead diacetate	multiple interactions	ISO	RGD:1345686	6480464	lead acetate promotes the reaction [Hemagglutinins results in increased secretion of CXCL8 protein]	CTD	PMID:22839698
lead(0)	increases expression	ISO	RGD:1345686	6480464	Lead results in increased expression of CXCL8 mRNA, Lead results in increased expression of CXCL8 protein	CTD	PMID:18464055, PMID:24106166
lead(0)	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lead results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:24106166, PMID:24709140
lead(2+)	increases expression	ISO	RGD:1345686	6480464	Lead results in increased expression of CXCL8 mRNA, Lead results in increased expression of CXCL8 protein	CTD	PMID:18464055, PMID:24106166
lead(2+)	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lead results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:24106166, PMID:24709140
lead(II) chloride	increases secretion	ISO	RGD:1345686	6480464	lead chloride results in increased secretion of CXCL8 protein	CTD	PMID:16099135
leflunomide	increases expression	ISO	RGD:1345686	6480464	leflunomide results in increased expression of CXCL8 mRNA	CTD	PMID:28988120
leptomycin B	multiple interactions	ISO	RGD:1345686	6480464	acteoside inhibits the reaction [leptomycin B results in increased secretion of CXCL8 protein], Quercetin inhibits the reaction [leptomycin B results in increased secretion of CXCL8 protein]	CTD	PMID:21967610
leptomycin B	increases secretion	ISO	RGD:1345686	6480464	leptomycin B results in increased secretion of CXCL8 protein	CTD	PMID:21967610
leukotriene B4	multiple interactions	ISO	RGD:1345686	6480464	Leukotriene B4 inhibits the reaction [zileuton inhibits the reaction [Histamine results in increased expression of CXCL8 protein]]	CTD	PMID:9609743
leukotriene B4	increases expression	ISO	RGD:1345686	6480464	Leukotriene B4 results in increased expression of CXCL8 mRNA, Leukotriene B4 results in increased expression of CXCL8 protein	CTD	PMID:9609743
leukotriene D4	multiple interactions	ISO	RGD:1345686	6480464	[Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein, zafirlukast inhibits the reaction [[Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein]	CTD	PMID:18704935
leupeptin	multiple interactions	ISO	RGD:1345686	6480464	leupeptin inhibits the reaction [Particulate Matter results in increased secretion of CXCL8 protein]	CTD	PMID:21818627
lidocaine	multiple interactions	ISO	RGD:1345686	6480464	[Methylprednisolone co-treated with Lidocaine] results in decreased expression of CXCL8 protein	CTD	PMID:11280320
limonene	increases expression	ISO	RGD:1345686	6480464	limonene results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
lipid As	increases expression	ISO	RGD:1345686	6480464	Lipid A results in increased expression of CXCL8 protein	CTD	PMID:16299289
lipid As	multiple interactions	ISO	RGD:1345686	6480464	[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of CXCL8 protein, [FK 565 co-treated with Lipid A] results in increased expression of CXCL8 protein	CTD	PMID:16299289
lipoarabinomannan	multiple interactions	ISO	RGD:1345686	6480464	CSF2 protein promotes the reaction [lipoarabinomannan results in increased secretion of CXCL8 protein]	CTD	PMID:12176910
lipoarabinomannan	increases secretion	ISO	RGD:1345686	6480464	lipoarabinomannan results in increased secretion of CXCL8 protein	CTD	PMID:12176910
lipophosphoglycan	multiple interactions	ISO	RGD:1345686	6480464	[lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of CXCL8 protein, [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of CXCL8 protein	CTD	PMID:15910421
lipopolysaccharide	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:10072544 more ...
lipopolysaccharide	increases secretion	ISO	RGD:1345686	6480464	Lipopolysaccharides results in increased secretion of CXCL8 protein, Lipopolysaccharides results in increased secretion of IL8 protein	CTD	PMID:12070353 more ...
lipopolysaccharide	increases expression	ISO	RGD:1345686	6480464	Lipopolysaccharides results in increased expression of CXCL8 more ...	CTD	PMID:10072544 more ...
lipopolysaccharide	multiple interactions	EXP		6480464	Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL15 mRNA] more ...	CTD	PMID:20384571, PMID:21307008
lipopolysaccharide	increases expression	EXP		6480464	Lipopolysaccharides results in increased expression of CXCL15 mRNA, Lipopolysaccharides results in increased expression of CXCL15 protein	CTD	PMID:20384571, PMID:21307008
lipoteichoic acid	multiple interactions	ISO	RGD:1345686	6480464	resveratrol inhibits the reaction [lipoteichoic acid results in increased secretion of CXCL8 protein]	CTD	PMID:23981542
lipoteichoic acid	increases secretion	ISO	RGD:1345686	6480464	lipoteichoic acid results in increased secretion of CXCL8 protein	CTD	PMID:22183712, PMID:23981542
lipoxin A4	multiple interactions	ISO	RGD:1345686	6480464	lipoxin A4 analog inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12235371 more ...
lipoxin A4	decreases expression	ISO	RGD:1345686	6480464	lipoxin A4 analog results in decreased expression of CXCL8 protein	CTD	PMID:21659618
lithium atom	increases expression	ISO	RGD:1345686	6480464	Lithium results in increased expression of CXCL8 mRNA	CTD	PMID:11756416
lithium atom	increases secretion	ISO	RGD:1345686	6480464	Lithium results in increased secretion of CXCL8 protein	CTD	PMID:11756416
lithium carbonate	increases expression	ISO	RGD:1345686	6480464	Lithium Carbonate results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
lithium carbonate	multiple interactions	ISO	RGD:1345686	6480464	[Lithium Carbonate co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
lithium hydride	increases expression	ISO	RGD:1345686	6480464	Lithium results in increased expression of CXCL8 mRNA	CTD	PMID:11756416
lithium hydride	increases secretion	ISO	RGD:1345686	6480464	Lithium results in increased secretion of CXCL8 protein	CTD	PMID:11756416
lithium(1+)	increases secretion	ISO	RGD:1345686	6480464	Lithium results in increased secretion of CXCL8 protein	CTD	PMID:11756416
lithium(1+)	increases expression	ISO	RGD:1345686	6480464	Lithium results in increased expression of CXCL8 mRNA	CTD	PMID:11756416
lithocholic acid	multiple interactions	ISO	RGD:1345686	6480464	Lithocholic Acid inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]	CTD	PMID:18515093
lucanthone	increases expression	ISO	RGD:1345686	6480464	Lucanthone results in increased expression of CXCL8 mRNA	CTD	PMID:21148553
Luliconazole	multiple interactions	ISO	RGD:1345686	6480464	luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]	CTD	PMID:23688403
luteolin	multiple interactions	ISO	RGD:1345686	6480464	Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA], Luteolin inhibits the reaction [chromium hexavalent ion results in increased secretion of CXCL8 protein]	CTD	PMID:25448439, PMID:30133131
LY294002	decreases expression	ISO	RGD:1345686	6480464	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of CXCL8 protein	CTD	PMID:23099361
LY294002	multiple interactions	EXP		6480464	[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with U 0126] inhibits the reaction [lead acetate results in increased secretion of CXCL15 protein]	CTD	PMID:24530660
LY294002	multiple interactions	ISO	RGD:1345686	6480464	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2 more ...	CTD	PMID:16611624 more ...
lycopene	multiple interactions	ISO	RGD:1345686	6480464	[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein] more ...	CTD	PMID:25551565
m-xylene	increases expression	ISO	RGD:1345686	6480464	3-xylene results in increased expression of CXCL8 protein	CTD	PMID:17993253
magnesium sulfate	increases expression	ISO	RGD:1345686	6480464	Magnesium Sulfate results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
magnesium sulfate	multiple interactions	ISO	RGD:1345686	6480464	Magnesium Sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]	CTD	PMID:16384605
mancozeb	multiple interactions	ISO	RGD:1345686	6480464	mancozeb inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]	CTD	PMID:16112155
manganese atom	increases secretion	ISO	RGD:1345686	6480464	Manganese results in increased secretion of CXCL8 protein	CTD	PMID:19263519
manganese(0)	increases secretion	ISO	RGD:1345686	6480464	Manganese results in increased secretion of CXCL8 protein	CTD	PMID:19263519
manganese(2+)	increases secretion	ISO	RGD:1345686	6480464	Manganese results in increased secretion of CXCL8 protein	CTD	PMID:19263519
manganese(II) chloride	affects expression	ISO	RGD:1345686	6480464	manganese chloride affects the expression of CXCL8 mRNA	CTD	PMID:27427241
manganese(II) chloride	increases expression	ISO	RGD:1345686	6480464	manganese chloride results in increased expression of CXCL8 mRNA	CTD	PMID:19815061
mangiferin	multiple interactions	ISO	RGD:1345686	6480464	mangiferin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA], mangiferin inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]	CTD	PMID:21420233
mangiferin	affects expression	EXP		6480464	mangiferin affects the expression of CXCL15 protein	CTD	PMID:21837981
mebendazole	increases expression	ISO	RGD:1345686	6480464	Mebendazole results in increased expression of CXCL8 mRNA, Mebendazole results in increased expression of CXCL8 protein	CTD	PMID:20116850 more ...
mebendazole	multiple interactions	ISO	RGD:1345686	6480464	U 0126 inhibits the reaction [Mebendazole results in increased secretion of CXCL8 protein]	CTD	PMID:20848085
mebendazole	increases secretion	ISO	RGD:1345686	6480464	Mebendazole results in increased secretion of CXCL8 protein	CTD	PMID:20848085
meclocycline	decreases expression	ISO	RGD:1345686	6480464	meclocycline results in decreased expression of CXCL8 protein	CTD	PMID:20116850
melittin	increases expression	ISO	RGD:1345686	6480464	Melitten results in increased expression of CXCL8 mRNA	CTD	PMID:17579088
menadione	affects expression	ISO	RGD:1345686	6480464	Vitamin K 3 affects the expression of CXCL8 mRNA	CTD	PMID:23410634
mepyramine	multiple interactions	ISO	RGD:1345686	6480464	HRH1 protein promotes the reaction [Pyrilamine results in decreased susceptibility to CXCL8 protein]	CTD	PMID:7522859
mepyramine	decreases response to substance	ISO	RGD:1345686	6480464	Pyrilamine results in decreased susceptibility to CXCL8 protein	CTD	PMID:7522859
mercury atom	increases expression	ISO	RGD:1345686	6480464	Mercury results in increased expression of CXCL8 protein	CTD	PMID:18393961
mercury dichloride	multiple interactions	ISO	RGD:1345686	6480464	[Mercuric Chloride co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
mercury dichloride	increases secretion	ISO	RGD:1345686	6480464	Mercuric Chloride results in increased secretion of CXCL8 protein	CTD	PMID:25458486
mercury dichloride	decreases expression	ISO	RGD:1345686	6480464	Mercuric Chloride results in decreased expression of CXCL8 mRNA	CTD	PMID:8560497
mercury dichloride	increases expression	ISO	RGD:1345686	6480464	Mercuric Chloride results in increased expression of CXCL8 mRNA, Mercuric Chloride results in increased expression of CXCL8 protein	CTD	PMID:20713136 more ...
mercury(0)	increases expression	ISO	RGD:1345686	6480464	Mercury results in increased expression of CXCL8 protein	CTD	PMID:18393961
mercury(2+)	increases expression	ISO	RGD:1345686	6480464	Mercury results in increased expression of CXCL8 protein	CTD	PMID:18393961
metformin	multiple interactions	ISO	RGD:1345686	6480464	Metformin inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]	CTD	PMID:16385087
metformin	increases expression	ISO	RGD:1345686	6480464	Metformin results in increased expression of CXCL8 mRNA	CTD	PMID:21316309
methimazole	increases expression	ISO	RGD:1345686	6480464	Methimazole results in increased expression of CXCL8 mRNA	CTD	PMID:20144635
methionine sulfoximine	decreases expression	ISO	RGD:1345686	6480464	Methionine Sulfoximine results in decreased expression of CXCL8 protein	CTD	PMID:20116850
methotrexate	increases secretion	ISO	RGD:1345686	6480464	Methotrexate results in increased secretion of CXCL8 protein	CTD	PMID:19100307, PMID:27605418
methotrexate	increases expression	ISO	RGD:1345686	6480464	Methotrexate results in increased expression of CXCL8 mRNA, Methotrexate results in increased expression of CXCL8 protein	CTD	PMID:17379860, PMID:24657277
methotrexate	decreases expression	ISO	RGD:1345686	6480464	Methotrexate results in decreased expression of CXCL8 more ...	CTD	PMID:15476228 more ...
methotrexate	multiple interactions	ISO	RGD:1345686	6480464	[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of CXCL8 mRNA, SB 203580 inhibits the reaction [Methotrexate results in increased secretion of CXCL8 protein]	CTD	PMID:19100307, PMID:24657277
methyl beta-cyclodextrin	multiple interactions	ISO	RGD:1345686	6480464	[methyl-beta-cyclodextrin results in decreased abundance of Cholesterol] inhibits the reaction [Polystyrenes inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]]	CTD	PMID:23274767
methyl methacrylate	increases expression	ISO	RGD:1345686	6480464	Methylmethacrylate results in increased expression of CXCL8 mRNA, Methylmethacrylate results in increased expression of CXCL8 protein	CTD	PMID:17498896, PMID:25617811
methyl non-2-ynoate	increases expression	ISO	RGD:1345686	6480464	2-nonynoic acid methyl ester results in increased expression of CXCL8 mRNA	CTD	PMID:21920952
methyl salicylate	increases expression	ISO	RGD:1345686	6480464	methyl salicylate results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
methylglyoxal	affects expression	ISO	RGD:1345686	6480464	Pyruvaldehyde analog affects the expression of CXCL8 mRNA	CTD	PMID:20200221
methylisothiazolinone	multiple interactions	ISO	RGD:1345686	6480464	2-methyl-4-isothiazolin-3-one results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:29110394
methylisothiazolinone	increases secretion	ISO	RGD:1345686	6480464	2-methyl-4-isothiazolin-3-one results in increased secretion of CXCL8 protein	CTD	PMID:30806763
methylisothiazolinone	increases expression	ISO	RGD:1345686	6480464	2-methyl-4-isothiazolin-3-one results in increased expression of CXCL8 mRNA	CTD	PMID:30806763
methylmercury chloride	increases expression	ISO	RGD:1345686	6480464	methylmercuric chloride results in increased expression of CXCL8 mRNA	CTD	PMID:27917510
methylmercury chloride	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:27917510
methylmercury chloride	increases secretion	ISO	RGD:1345686	6480464	methylmercuric chloride results in increased secretion of CXCL8 protein	CTD	PMID:27917510
methylmercury(1+)	affects expression	ISO	RGD:1345686	6480464	methylmercury II affects the expression of CXCL8 mRNA	CTD	PMID:26314263
microcystin-LR	increases expression	EXP		6480464	cyanoginosin LR results in increased expression of CXCL8 protein	CTD	PMID:26984711
mifepristone	multiple interactions	ISO	RGD:1345686	6480464	Mifepristone inhibits the reaction [Hydrocortisone results in decreased susceptibility to CXCL8 protein], Mifepristone inhibits the reaction [Progesterone inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased expression of CXCL8 mRNA]]	CTD	PMID:15866594, PMID:7522859
mifepristone	multiple interactions	EXP		6480464	Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of CXCL15 protein]	CTD	PMID:12504806
milrinone	multiple interactions	ISO	RGD:1345686	6480464	Milrinone promotes the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]	CTD	PMID:21088047
minocycline	increases expression	ISO	RGD:1345686	6480464	Minocycline results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
minocycline	decreases expression	ISO	RGD:1345686	6480464	Minocycline results in decreased expression of CXCL8 protein	CTD	PMID:20116850
mitomycin C	increases expression	ISO	RGD:1345686	6480464	Mitomycin results in increased expression of CXCL8 mRNA	CTD	PMID:20002897, PMID:29594315
mitomycin C	increases secretion	ISO	RGD:1345686	6480464	Mitomycin results in increased secretion of CXCL8 protein	CTD	PMID:20002897
mitomycin C	multiple interactions	ISO	RGD:1345686	6480464	Dexamethasone inhibits the reaction [Mitomycin results in increased expression of CXCL8 mRNA], Dexamethasone inhibits the reaction [Mitomycin results in increased secretion of CXCL8 protein]	CTD	PMID:20002897
Mizoribine	multiple interactions	ISO	RGD:1345686	6480464	[mizoribine co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
montelukast	multiple interactions	ISO	RGD:1345686	6480464	[montelukast co-treated with Cetirizine] results in decreased expression of CXCL8 protein more ...	CTD	PMID:15061398, PMID:20083671
morphine	multiple interactions	ISO	RGD:1345686	6480464	CTAP octapeptide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]] more ...	CTD	PMID:24068670
moxifloxacin	multiple interactions	ISO	RGD:1345686	6480464	moxifloxacin inhibits the reaction [Camptothecin results in increased secretion of CXCL8 protein]	CTD	PMID:18191106
moxifloxacin	decreases secretion	ISO	RGD:1345686	6480464	moxifloxacin results in decreased secretion of CXCL8 protein	CTD	PMID:16352735, PMID:18191106
muramyl dipeptide	multiple interactions	ISO	RGD:1345686	6480464	[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA more ...	CTD	PMID:16299289 more ...
muramyl dipeptide	increases expression	ISO	RGD:1345686	6480464	Acetylmuramyl-Alanyl-Isoglutamine results in increased expression of CXCL8 protein	CTD	PMID:16299289
mycophenolic acid	increases expression	ISO	RGD:1345686	6480464	Mycophenolic Acid results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
mycophenolic acid	multiple interactions	ISO	RGD:1345686	6480464	Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased secretion of CXCL8 protein]	CTD	PMID:20302854
mycophenolic acid	increases expression	EXP		6480464	Mycophenolic Acid results in increased expression of CXCL15 mRNA	CTD	PMID:19818335
mycophenolic acid	increases secretion	ISO	RGD:1345686	6480464	Mycophenolic Acid results in increased secretion of CXCL8 protein	CTD	PMID:29408666
mycotoxin	decreases expression	EXP		6480464	Mycotoxins results in decreased expression of CXCL15 mRNA	CTD	PMID:19818335
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	increases secretion	ISO	RGD:1345686	6480464	N more ...	CTD	PMID:18615482
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	multiple interactions	ISO	RGD:1345686	6480464	N more ...	CTD	PMID:26303504
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide	multiple interactions	ISO	RGD:1345686	6480464	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]] more ...	CTD	PMID:17823304, PMID:22363678
N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE	multiple interactions	ISO	RGD:1345686	6480464	Diphenhydramine inhibits the reaction [Histamine results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:11336536 more ...
N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE	decreases response to substance	ISO	RGD:1345686	6480464	Diphenhydramine results in decreased susceptibility to CXCL8 protein	CTD	PMID:7522859
N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide	multiple interactions	ISO	RGD:1345686	6480464	N-(3 more ...	CTD	PMID:19747488, PMID:20932985
N-acetyl-L-cysteine	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein] more ...	CTD	PMID:10202011 more ...
N-acetyl-L-cysteine	decreases expression	ISO	RGD:1345686	6480464	Acetylcysteine results in decreased expression of CXCL8 mRNA	CTD	PMID:21920952, PMID:22385246
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:11698246 more ...
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal	increases secretion	ISO	RGD:1345686	6480464	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased secretion of CXCL8 protein	CTD	PMID:16392133
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal	increases expression	ISO	RGD:1345686	6480464	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA	CTD	PMID:12208513 more ...
N-ethyl-5'-carboxamidoadenosine	increases expression	ISO	RGD:1345686	6480464	Adenosine-5'-(N-ethylcarboxamide) results in increased expression of CXCL8 mRNA, Adenosine-5'-(N-ethylcarboxamide) results in increased expression of CXCL8 protein	CTD	PMID:23266380
N-ethyl-5'-carboxamidoadenosine	multiple interactions	ISO	RGD:1345686	6480464	4'-chlorodiazepam inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased expression of CXCL8 protein] more ...	CTD	PMID:23266380
N-formyl-L-methionyl-L-leucyl-L-phenylalanine	increases expression	ISO	RGD:1345686	6480464	N-Formylmethionine Leucyl-Phenylalanine results in increased expression of CXCL8 mRNA, N-Formylmethionine Leucyl-Phenylalanine results in increased expression of CXCL8 protein	CTD	PMID:12946449, PMID:17459229
N-formyl-L-methionyl-L-leucyl-L-phenylalanine	increases secretion	ISO	RGD:1345686	6480464	N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of CXCL8 protein	CTD	PMID:11566077, PMID:17459229
N-formyl-L-methionyl-L-leucyl-L-phenylalanine	multiple interactions	ISO	RGD:1345686	6480464	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of CXCL8 protein] more ...	CTD	PMID:12946449, PMID:17459229
N-tosyl-L-phenylalanyl chloromethyl ketone	multiple interactions	ISO	RGD:1345686	6480464	Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Chloroquine results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:10540334 more ...
N-tosyl-L-phenylalanyl chloromethyl ketone	decreases secretion	ISO	RGD:1345686	6480464	Tosylphenylalanyl Chloromethyl Ketone results in decreased secretion of CXCL8 protein	CTD	PMID:23844176
NADP zwitterion	multiple interactions	ISO	RGD:1345686	6480464	[Benzo(a)pyrene co-treated with CXCL8 protein] results in decreased abundance of NADP	CTD	PMID:28238931
NADP(+)	multiple interactions	ISO	RGD:1345686	6480464	[Benzo(a)pyrene co-treated with CXCL8 protein] results in decreased abundance of NADP	CTD	PMID:28238931
nandrolone	multiple interactions	ISO	RGD:1345686	6480464	Nandrolone promotes the reaction [endotoxin, Escherichia coli results in increased expression of CXCL8 protein]	CTD	PMID:28412309
naphthalene	increases expression	ISO	RGD:1345686	6480464	naphthalene results in increased expression of CXCL8 mRNA, naphthalene results in increased expression of CXCL8 protein	CTD	PMID:14595851
naringin	multiple interactions	EXP		6480464	naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL15 mRNA], naringin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CXCL15 protein]	CTD	PMID:22965302
neurotensin	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:17000667
neurotensin	increases expression	ISO	RGD:1345686	6480464	Neurotensin results in increased expression of CXCL8 mRNA, Neurotensin results in increased expression of CXCL8 protein	CTD	PMID:17000667
nickel atom	increases expression	ISO	RGD:1345686	6480464	Nickel analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:20632048 more ...
nickel atom	multiple interactions	ISO	RGD:1345686	6480464	Nickel results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:23624239
nickel dichloride	increases expression	ISO	RGD:1345686	6480464	nickel chloride results in increased expression of CXCL8 mRNA, nickel chloride results in increased expression of CXCL8 protein	CTD	PMID:11378323 more ...
nickel dichloride	increases secretion	ISO	RGD:1345686	6480464	nickel chloride results in increased secretion of CXCL8 protein	CTD	PMID:21473897 more ...
nickel dichloride	decreases expression	ISO	RGD:1345686	6480464	nickel chloride results in decreased expression of CXCL8 mRNA	CTD	PMID:23844176, PMID:27427241
nickel dichloride	decreases secretion	ISO	RGD:1345686	6480464	nickel chloride results in decreased secretion of CXCL8 protein	CTD	PMID:23844176
nickel dichloride	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nickel chloride results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:23090859 more ...
nickel sulfate	multiple interactions	ISO	RGD:1345686	6480464	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein] more ...	CTD	PMID:15081272 more ...
nickel sulfate	increases secretion	ISO	RGD:1345686	6480464	nickel sulfate results in increased secretion of CXCL8 protein	CTD	PMID:12781210 more ...
nickel sulfate	decreases expression	ISO	RGD:1345686	6480464	nickel sulfate results in decreased expression of CXCL8 mRNA	CTD	PMID:22714537
nickel sulfate	affects expression	ISO	RGD:1345686	6480464	nickel sulfate affects the expression of CXCL8 mRNA	CTD	PMID:18202158
nickel sulfate	increases expression	ISO	RGD:1345686	6480464	nickel sulfate results in increased expression of CXCL8 mRNA, nickel sulfate results in increased expression of CXCL8 protein	CTD	PMID:11978798 more ...
nicotinamide	increases expression	ISO	RGD:1345686	6480464	Niacinamide results in increased expression of CXCL8 mRNA	CTD	PMID:22385246
nicotinamide	multiple interactions	ISO	RGD:1345686	6480464	[Niacinamide co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA, [Niacinamide results in decreased activity of SIRT1 protein] which results in increased expression of CXCL8 mRNA	CTD	PMID:24894820, PMID:29594315
nicotine	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:22119045, PMID:23199342
nicotine	increases expression	ISO	RGD:1345686	6480464	Nicotine results in increased expression of CXCL8 mRNA	CTD	PMID:22119045
nicotinic acid	multiple interactions	ISO	RGD:1345686	6480464	[Ubiquinone co-treated with Niacin co-treated with Riboflavin] promotes the reaction [Tamoxifen results in decreased expression of CXCL8 protein]	CTD	PMID:17516992
nifedipine	multiple interactions	ISO	RGD:1345686	6480464	[Nifedipine co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA], Nifedipine inhibits the reaction [nickel chloride results in increased expression of CXCL8 mRNA]	CTD	PMID:18938131, PMID:25045119
nimesulide	affects expression	ISO	RGD:1345686	6480464	nimesulide affects the expression of CXCL8 protein	CTD	PMID:17380299
nimesulide	multiple interactions	ISO	RGD:1345686	6480464	nimesulide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of CXCL8 protein], nimesulide inhibits the reaction [Zymosan analog results in increased expression of CXCL8 protein]	CTD	PMID:12946449
nitric oxide	increases expression	ISO	RGD:1345686	6480464	Nitric Oxide results in increased expression of CXCL8 protein	CTD	PMID:10619828
nitrofurazone	multiple interactions	ISO	RGD:1345686	6480464	[Nitrofurazone co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
nitrofurazone	increases expression	ISO	RGD:1345686	6480464	Nitrofurazone results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
nitrogen dioxide	increases secretion	ISO	RGD:1345686	6480464	Nitrogen Dioxide results in increased secretion of CXCL8 protein	CTD	PMID:22331494 more ...
nitrogen dioxide	increases expression	ISO	RGD:1345686	6480464	Nitrogen Dioxide results in increased expression of CXCL8 mRNA	CTD	PMID:27206323, PMID:8584542
nitroglycerin	increases expression	ISO	RGD:1345686	6480464	Nitroglycerin results in increased expression of CXCL8 mRNA, Nitroglycerin results in increased expression of CXCL8 protein	CTD	PMID:10884648, PMID:17470570
Nivalenol	increases expression	ISO	RGD:1345686	6480464	nivalenol results in increased expression of CXCL8 mRNA	CTD	PMID:17166736
nocodazole	increases expression	ISO	RGD:1345686	6480464	Nocodazole results in increased expression of CXCL8 protein	CTD	PMID:20116850
Nodularin	multiple interactions	ISO	RGD:1345686	6480464	sauchinone inhibits the reaction [nodularin results in increased expression of CXCL8 mRNA]	CTD	PMID:27061667
Nodularin	increases expression	ISO	RGD:1345686	6480464	nodularin results in increased expression of CXCL8 mRNA	CTD	PMID:27061667
nonane	increases secretion	ISO	RGD:1345686	6480464	nonane results in increased secretion of CXCL8 protein	CTD	PMID:19720135
Nonidet P-40	decreases expression	ISO	RGD:1345686	6480464	Nonidet P-40 results in decreased expression of CXCL8 mRNA	CTD	PMID:26552463
NS-398	multiple interactions	ISO	RGD:1345686	6480464	[4-phenylbutyric acid co-treated with N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide] results in decreased expression of CXCL8 protein more ...	CTD	PMID:12946449 more ...
o-anisidine	increases expression	ISO	RGD:1345686	6480464	2-anisidine results in increased expression of CXCL8 protein	CTD	PMID:28089782
o-anisidine	affects expression	ISO	RGD:1345686	6480464	2-anisidine affects the expression of CXCL8 mRNA, 2-anisidine affects the expression of IL8 mRNA	CTD	PMID:28089782
o-xylene	increases expression	ISO	RGD:1345686	6480464	2-xylene results in increased expression of CXCL8 mRNA	CTD	PMID:20359517
ochratoxin A	multiple interactions	ISO	RGD:1345686	6480464	ochratoxin A inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein], Quercetin inhibits the reaction [ochratoxin A results in increased expression of CXCL8 protein]	CTD	PMID:18308354, PMID:25532488
ochratoxin A	decreases expression	ISO	RGD:1345686	6480464	ochratoxin A metabolite results in decreased expression of CXCL8 mRNA, ochratoxin A results in decreased expression of CXCL8 mRNA	CTD	PMID:26314263, PMID:30763683
ochratoxin A	increases expression	ISO	RGD:1345686	6480464	ochratoxin A results in increased expression of CXCL8 mRNA, ochratoxin A results in increased expression of CXCL8 protein	CTD	PMID:25532488, PMID:28286205
octadecanoic acid	increases expression	ISO	RGD:1345686	6480464	stearic acid results in increased expression of CXCL8 mRNA	CTD	PMID:21745629
octanoic acid	increases expression	ISO	RGD:1345686	6480464	octanoic acid results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
oleic acid	multiple interactions	ISO	RGD:1345686	6480464	[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:23348005, PMID:30547786
oleic acid	increases expression	ISO	RGD:1345686	6480464	Oleic Acid results in increased expression of CXCL8 protein	CTD	PMID:23348005
orlistat	multiple interactions	ISO	RGD:1345686	6480464	orlistat inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]	CTD	PMID:21088047
oroxylin A	multiple interactions	EXP		6480464	5 more ...	CTD	PMID:29476730
oxytetracycline	decreases expression	ISO	RGD:1345686	6480464	Oxytetracycline results in decreased expression of CXCL8 protein	CTD	PMID:20116850
ozone	multiple interactions	EXP		6480464	SLC11A2 protein inhibits the reaction [Ozone results in increased secretion of CXCL15 protein]	CTD	PMID:16905637
ozone	increases expression	ISO	RGD:1345686	6480464	Ozone results in increased expression of CXCL8 mRNA, Ozone results in increased expression of CXCL8 protein	CTD	PMID:11781168 more ...
ozone	increases secretion	ISO	RGD:1345686	6480464	Ozone results in increased secretion of CXCL8 protein	CTD	PMID:19162161
ozone	multiple interactions	ISO	RGD:1345686	6480464	[Acrolein co-treated with Formaldehyde co-treated with Ozone] results in increased expression of CXCL8 protein more ...	CTD	PMID:11781168 more ...
paclitaxel	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [CXCL8 results in decreased susceptibility to Paclitaxel] more ...	CTD	PMID:16499908 more ...
paclitaxel	increases expression	ISO	RGD:1345686	6480464	Paclitaxel results in increased expression of CXCL8 protein	CTD	PMID:14698135
paclitaxel	affects response to substance	ISO	RGD:1345686	6480464	CXCL8 protein affects the susceptibility to Paclitaxel	CTD	PMID:16217747
paclitaxel	decreases response to substance	ISO	RGD:1345686	6480464	CXCL8 results in decreased susceptibility to Paclitaxel	CTD	PMID:21742513
palmatine	decreases expression	ISO	RGD:1345686	6480464	palmatine results in decreased expression of CXCL8 protein	CTD	PMID:20116850
paracetamol	increases secretion	EXP		6480464	Acetaminophen results in increased secretion of CXCL8 protein	CTD	PMID:27161652
paracetamol	decreases expression	ISO	RGD:1345686	6480464	Acetaminophen results in decreased expression of CXCL8 mRNA	CTD	PMID:26690555, PMID:29067470
paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of CXCL15 mRNA	CTD	PMID:12051698
paracetamol	multiple interactions	EXP		6480464	Biflavonoids inhibits the reaction [Acetaminophen results in increased secretion of CXCL8 protein], S100A9 protein promotes the reaction [Acetaminophen results in increased expression of CXCL15 mRNA]	CTD	PMID:12051698, PMID:27161652
paracetamol	increases expression	ISO	RGD:1345686	6480464	Acetaminophen results in increased expression of CXCL8 mRNA, Acetaminophen results in increased expression of CXCL8 protein	CTD	PMID:12654133, PMID:21420995
paracetamol	multiple interactions	ISO	RGD:1345686	6480464	[Acetaminophen co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
paraquat	increases secretion	ISO	RGD:1345686	6480464	Paraquat results in increased secretion of CXCL8 protein	CTD	PMID:20883675
paraquat	increases expression	ISO	RGD:1345686	6480464	Paraquat results in increased expression of CXCL8 more ...	CTD	PMID:20506652 more ...
paraquat	multiple interactions	ISO	RGD:1345686	6480464	[Paraquat results in increased activity of RELA protein] which results in increased expression of CXCL8 mRNA more ...	CTD	PMID:20506652 more ...
paricalcitol	multiple interactions	ISO	RGD:1345686	6480464	[Phosphorus co-treated with paricalcitol] results in decreased expression of CXCL8 mRNA	CTD	PMID:17715259
parthenolide	multiple interactions	ISO	RGD:1345686	6480464	parthenolide inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased expression of and results in increased secretion of CXCL8 protein] more ...	CTD	PMID:18413660, PMID:20307528
patulin	multiple interactions	ISO	RGD:1345686	6480464	Patulin inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]	CTD	PMID:18308354
PD 0325901	decreases expression	ISO	RGD:1345686	6480464	PD 0325901 results in decreased expression of CXCL8 mRNA	CTD	PMID:25119042
PD 0325901	multiple interactions	ISO	RGD:1345686	6480464	[PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of CXCL8 mRNA	CTD	PMID:25119042
PD 168393	multiple interactions	ISO	RGD:1345686	6480464	PD168393 inhibits the reaction [resveratrol results in increased expression of CXCL8]	CTD	PMID:23527233
pemetrexed	multiple interactions	ISO	RGD:1345686	6480464	[Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of CXCL8 mRNA, [Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of CXCL8 protein	CTD	PMID:22975265
pentachlorophenol	increases expression	ISO	RGD:1345686	6480464	Pentachlorophenol results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
pentamidine	multiple interactions	ISO	RGD:1345686	6480464	[Pentamidine co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
pentanal	affects expression	ISO	RGD:1345686	6480464	pentanal analog affects the expression of CXCL8 mRNA	CTD	PMID:20200221
pentanal	increases secretion	ISO	RGD:1345686	6480464	pentanal results in increased secretion of CXCL8 protein	CTD	PMID:26079696
pentanal	increases expression	ISO	RGD:1345686	6480464	pentanal results in increased expression of CXCL8 mRNA	CTD	PMID:26079696
peptidoglycan	multiple interactions	ISO	RGD:1345686	6480464	[Lipopolysaccharides co-treated with Peptidoglycan] results in increased secretion of CXCL8 protein, CSF2 protein promotes the reaction [Peptidoglycan results in increased secretion of CXCL8 protein]	CTD	PMID:12176910, PMID:21355852
peptidoglycan	increases expression	ISO	RGD:1345686	6480464	Peptidoglycan results in increased expression of CXCL8 mRNA	CTD	PMID:15860229, PMID:15893496
peptidoglycan	increases secretion	ISO	RGD:1345686	6480464	Peptidoglycan results in increased secretion of CXCL8 protein	CTD	PMID:12176910, PMID:15893496
perfluorooctane-1-sulfonic acid	multiple interactions	ISO	RGD:1345686	6480464	perfluorooctane sulfonic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA], perfluorooctane sulfonic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]	CTD	PMID:21075133
perfluorooctanoic acid	multiple interactions	ISO	RGD:1345686	6480464	perfluorooctanoic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:21075133
perfluorooctanoic acid	increases expression	ISO	RGD:1345686	6480464	perfluorooctanoic acid results in increased expression of CXCL8 mRNA	CTD	PMID:22322153
perillyl aldehyde	increases expression	ISO	RGD:1345686	6480464	perillaldehyde results in increased expression of CXCL8 mRNA	CTD	PMID:20491607
peroxynitrous acid	multiple interactions	ISO	RGD:1345686	6480464	ebselen inhibits the reaction [Peroxynitrous Acid results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:14572605
peroxynitrous acid	increases expression	ISO	RGD:1345686	6480464	Peroxynitrous Acid results in increased expression of CXCL8 more ...	CTD	PMID:12235371, PMID:14572605
perylene	decreases expression	ISO	RGD:1345686	6480464	Perylene results in decreased expression of CXCL8 mRNA	CTD	PMID:23724284
phenanthrene	increases expression	ISO	RGD:1345686	6480464	phenanthrene results in increased expression of CXCL8 mRNA	CTD	PMID:18434080
phenanthrene	multiple interactions	ISO	RGD:1345686	6480464	TNF protein promotes the reaction [phenanthrene results in increased expression of CXCL8 mRNA]	CTD	PMID:18434080
phenethyl caffeate	multiple interactions	ISO	RGD:1345686	6480464	caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of CXCL8 mRNA]	CTD	PMID:16085347
phenethyl isothiocyanate	multiple interactions	ISO	RGD:1345686	6480464	phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]	CTD	PMID:23724058
phenobarbital	affects expression	ISO	RGD:1345686	6480464	Phenobarbital affects the expression of CXCL8 mRNA	CTD	PMID:19159669
phenol	increases expression	ISO	RGD:1345686	6480464	Phenol results in increased expression of CXCL8 mRNA, Phenol results in increased expression of CXCL8 protein	CTD	PMID:8006454
phenol	multiple interactions	ISO	RGD:1345686	6480464	IL1A protein affects the reaction [Phenol results in increased expression of CXCL8 protein], TNF protein affects the reaction [Phenol results in increased expression of CXCL8 protein]	CTD	PMID:8006454
phenoxymethylpenicillin	increases expression	ISO	RGD:1345686	6480464	Penicillin V results in increased expression of CXCL8 mRNA, Penicillin V results in increased expression of CXCL8 protein	CTD	PMID:22609641
phenyl benzoate	increases expression	ISO	RGD:1345686	6480464	diphenylcarboxylate results in increased expression of CXCL8 mRNA, diphenylcarboxylate results in increased expression of CXCL8 protein	CTD	PMID:25617811, PMID:27965148
phenylacetaldehyde	increases secretion	ISO	RGD:1345686	6480464	phenylacetaldehyde results in increased secretion of CXCL8 protein	CTD	PMID:17118622
phorbol 13-acetate 12-myristate	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:10072544 more ...
phorbol 13-acetate 12-myristate	increases secretion	ISO	RGD:1345686	6480464	Tetradecanoylphorbol Acetate results in increased secretion of CXCL8 protein	CTD	PMID:16376386 more ...
phorbol 13-acetate 12-myristate	increases expression	ISO	RGD:1345686	6480464	Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA, Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein	CTD	PMID:12765200 more ...
phosphorus atom	multiple interactions	ISO	RGD:1345686	6480464	[Phosphorus co-treated with paricalcitol] results in decreased expression of CXCL8 mRNA	CTD	PMID:17715259
phosphorus(.)	multiple interactions	ISO	RGD:1345686	6480464	[Phosphorus co-treated with paricalcitol] results in decreased expression of CXCL8 mRNA	CTD	PMID:17715259
phthalic anhydride	increases expression	ISO	RGD:1345686	6480464	phthalic anhydride results in increased expression of CXCL8 mRNA	CTD	PMID:21920952
picolinic acid	multiple interactions	ISO	RGD:1345686	6480464	picolinic acid inhibits the reaction [Glucose results in increased secretion of CXCL8 protein]	CTD	PMID:17665966
pioglitazone	decreases expression	ISO	RGD:1345686	6480464	Pioglitazone results in decreased expression of CXCL8 mRNA	CTD	PMID:30031879
pioglitazone	multiple interactions	EXP		6480464	[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of CXCL15 mRNA	CTD	PMID:27935865
pirinixic acid	increases expression	EXP		6480464	pirinixic acid results in increased expression of CXCL15 mRNA	CTD	PMID:20813756
piroxicam	decreases expression	ISO	RGD:1345686	6480464	Piroxicam results in decreased expression of CXCL8 mRNA, Piroxicam results in decreased expression of CXCL8 protein	CTD	PMID:19192274
platinum	increases expression	ISO	RGD:1345686	6480464	Platinum analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
platinum(0)	increases expression	ISO	RGD:1345686	6480464	Platinum analog results in increased expression of CXCL8 mRNA	CTD	PMID:23724284
platycodin D	multiple interactions	ISO	RGD:1345686	6480464	platycodin D inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]	CTD	PMID:27743553
poly(I:C)	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:18779317 more ...
poly(I:C)	increases secretion	ISO	RGD:1345686	6480464	Poly I-C results in increased secretion of CXCL8 protein	CTD	PMID:17669408 more ...
poly(I:C)	increases expression	ISO	RGD:1345686	6480464	Poly I-C results in increased expression of CXCL8 more ...	CTD	PMID:18779317 more ...
polymyxin B1	multiple interactions	ISO	RGD:1345686	6480464	Polymyxin B inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18406506 more ...
polymyxin B2	multiple interactions	ISO	RGD:1345686	6480464	Polymyxin B inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18406506 more ...
potassium chromate	decreases expression	ISO	RGD:1345686	6480464	potassium chromate(VI) results in decreased expression of CXCL8 mRNA	CTD	PMID:22714537
potassium dichromate	increases secretion	ISO	RGD:1345686	6480464	Potassium Dichromate results in increased secretion of CXCL8 protein	CTD	PMID:15679580
potassium dichromate	multiple interactions	ISO	RGD:1345686	6480464	[Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:24964617
potassium dichromate	increases expression	EXP		6480464	Potassium Dichromate results in increased expression of CXCL15 mRNA	CTD	PMID:23608068
pravastatin	multiple interactions	ISO	RGD:1345686	6480464	Pravastatin inhibits the reaction [lopinavir-ritonavir drug combination results in increased secretion of CXCL8 protein], Pravastatin inhibits the reaction [Ritonavir results in increased secretion of CXCL8 protein]	CTD	PMID:20884875
prazosin	multiple interactions	ISO	RGD:1345686	6480464	Prazosin inhibits the reaction [Norepinephrine results in increased secretion of CXCL8 protein]	CTD	PMID:16782692
prednisolone	decreases secretion	EXP		6480464	Prednisolone results in decreased secretion of CXCL15 protein	CTD	PMID:14694204
prednisolone	decreases secretion	ISO	RGD:1345686	6480464	Prednisolone results in decreased secretion of CXCL8 protein	CTD	PMID:17379860
prednisolone	decreases expression	ISO	RGD:1345686	6480464	Prednisolone results in decreased expression of CXCL8 mRNA, Prednisolone results in decreased expression of CXCL8 protein	CTD	PMID:17379860, PMID:19192274
probenecid	increases expression	ISO	RGD:1345686	6480464	Probenecid analog results in increased expression of CXCL8 mRNA, Probenecid metabolite results in increased expression of CXCL8 protein	CTD	PMID:24104198, PMID:26528891
progesterone	multiple interactions	ISO	RGD:1345686	6480464	[Estradiol co-treated with Progesterone] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:15866594 more ...
progesterone	increases expression	ISO	RGD:1345686	6480464	Progesterone results in increased expression of CXCL8 mRNA, Progesterone results in increased expression of CXCL8 protein	CTD	PMID:20130130 more ...
progesterone	increases secretion	ISO	RGD:1345686	6480464	CXCL8 protein results in increased secretion of Progesterone	CTD	PMID:15780010
propanal	increases expression	ISO	RGD:1345686	6480464	propionaldehyde results in increased expression of CXCL8 mRNA	CTD	PMID:26079696
propanal	increases secretion	ISO	RGD:1345686	6480464	propionaldehyde results in increased secretion of CXCL8 protein	CTD	PMID:26079696
propidium	decreases expression	ISO	RGD:1345686	6480464	Propidium results in decreased expression of CXCL8 protein	CTD	PMID:20116850
propofol	multiple interactions	EXP		6480464	Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL15 mRNA], Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL15 protein]	CTD	PMID:21307008
Proscillaridin	decreases expression	ISO	RGD:1345686	6480464	Proscillaridin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
prostaglandin E2	multiple interactions	ISO	RGD:1345686	6480464	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein] more ...	CTD	PMID:17709599 more ...
prostaglandin E2	increases secretion	ISO	RGD:1345686	6480464	Dinoprostone results in increased secretion of CXCL8 protein	CTD	PMID:17709599
protein kinase inhibitor	multiple interactions	ISO	RGD:1345686	6480464	Protein Kinase Inhibitors inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein], Protein Kinase Inhibitors inhibits the reaction [Ozone results in increased expression of CXCL8 protein]	CTD	PMID:25303742, PMID:28003376
puromycin	decreases expression	ISO	RGD:1345686	6480464	Puromycin results in decreased expression of CXCL8 protein	CTD	PMID:20116850
pyrene	increases expression	ISO	RGD:1345686	6480464	pyrene results in increased expression of CXCL8 mRNA, pyrene results in increased expression of CXCL8 protein	CTD	PMID:12946434, PMID:18434080
pyrene	increases secretion	ISO	RGD:1345686	6480464	pyrene results in increased secretion of CXCL8 protein	CTD	PMID:23458896
pyrene	multiple interactions	ISO	RGD:1345686	6480464	TNF protein promotes the reaction [pyrene results in increased expression of CXCL8 mRNA]	CTD	PMID:18434080
pyrrolidine dithiocarbamate	multiple interactions	ISO	RGD:1345686	6480464	pyrrolidine dithiocarbamic acid affects the reaction [IL1B results in increased expression of CXCL8 protein] more ...	CTD	PMID:11306435 more ...
pyrvinium	multiple interactions	ISO	RGD:1345686	6480464	pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CXCL8 mRNA]	CTD	PMID:27542212
pyrvinium	decreases expression	ISO	RGD:1345686	6480464	pyrvinium results in decreased expression of CXCL8 protein	CTD	PMID:20116850
quartz	increases expression	ISO	RGD:1345686	6480464	Quartz results in increased expression of CXCL8 mRNA	CTD	PMID:27917503
quartz	increases secretion	ISO	RGD:1345686	6480464	Quartz results in increased secretion of CXCL8 protein	CTD	PMID:29102675
quercetin	decreases expression	ISO	RGD:1345686	6480464	Quercetin results in decreased expression of CXCL8 mRNA, Quercetin results in decreased expression of CXCL8 protein	CTD	PMID:21756928, PMID:23099361
quercetin	decreases secretion	ISO	RGD:1345686	6480464	Quercetin results in decreased secretion of CXCL8 protein	CTD	PMID:21756928 more ...
quercetin	increases secretion	ISO	RGD:1345686	6480464	Quercetin results in increased secretion of CXCL8 protein	CTD	PMID:21371465
quercetin	increases expression	ISO	RGD:1345686	6480464	Quercetin results in increased expression of CXCL8 mRNA	CTD	PMID:15309432 more ...
quercetin	affects expression	ISO	RGD:1345686	6480464	Quercetin affects the expression of CXCL8 mRNA	CTD	PMID:17717114
quercetin	multiple interactions	ISO	RGD:1345686	6480464	[Quercetin co-treated with TGFA protein] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:15180920 more ...
quercetin 3-O-beta-D-glucofuranoside	increases expression	ISO	RGD:1345686	6480464	isoquercitrin results in increased expression of CXCL8 mRNA	CTD	PMID:30597948
quercetin 3-O-beta-D-glucopyranoside	increases expression	ISO	RGD:1345686	6480464	isoquercitrin results in increased expression of CXCL8 mRNA	CTD	PMID:30597948
quinazolines	multiple interactions	ISO	RGD:1345686	6480464	Quinazolines inhibits the reaction [IL33 protein results in increased expression of CXCL8 mRNA], Quinazolines inhibits the reaction [IL33 protein results in increased expression of CXCL8 protein]	CTD	PMID:23585867
raloxifene	multiple interactions	ISO	RGD:1345686	6480464	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA	CTD	PMID:19059307
Rebamipide	decreases expression	ISO	RGD:1345686	6480464	rebamipide results in decreased expression of CXCL8 mRNA	CTD	PMID:20198424
Repaglinide	decreases expression	ISO	RGD:1345686	6480464	repaglinide metabolite results in decreased expression of CXCL8 mRNA	CTD	PMID:26528891
resorcinol	increases secretion	ISO	RGD:1345686	6480464	resorcinol results in increased secretion of CXCL8 protein	CTD	PMID:30806763
resorcinol	increases expression	ISO	RGD:1345686	6480464	resorcinol results in increased expression of CXCL8 mRNA	CTD	PMID:30806763
resveratrol	increases expression	ISO	RGD:1345686	6480464	resveratrol results in increased expression of CXCL8 mRNA, resveratrol results in increased expression of CXCL8 protein	CTD	PMID:15280659 more ...
resveratrol	decreases stability	ISO	RGD:1345686	6480464	resveratrol results in decreased stability of CXCL8 mRNA	CTD	PMID:25352548
resveratrol	decreases expression	ISO	RGD:1345686	6480464	resveratrol analog results in decreased expression of CXCL8 mRNA, resveratrol results in decreased expression of CXCL8 mRNA	CTD	PMID:21756928 more ...
resveratrol	decreases secretion	ISO	RGD:1345686	6480464	resveratrol results in decreased secretion of CXCL8 protein	CTD	PMID:22933405, PMID:23661232
resveratrol	decreases expression	EXP		6480464	Resveratrol results in decreased expression of CXCL15 mRNA, Resveratrol results in decreased expression of CXCL15 protein	CTD	PMID:18826146
resveratrol	increases secretion	ISO	RGD:1345686	6480464	resveratrol results in increased secretion of CXCL8 protein	CTD	PMID:21756928 more ...
resveratrol	multiple interactions	ISO	RGD:1345686	6480464	6-formylindolo(3 more ...	CTD	PMID:12765200 more ...
riboflavin	multiple interactions	ISO	RGD:1345686	6480464	[Ubiquinone co-treated with Niacin co-treated with Riboflavin] promotes the reaction [Tamoxifen results in decreased expression of CXCL8 protein]	CTD	PMID:17516992
ritonavir	multiple interactions	ISO	RGD:1345686	6480464	Pravastatin inhibits the reaction [Ritonavir results in increased secretion of CXCL8 protein]	CTD	PMID:20884875
ritonavir	decreases expression	ISO	RGD:1345686	6480464	Ritonavir results in decreased expression of CXCL8	CTD	PMID:26626330
ritonavir	increases secretion	ISO	RGD:1345686	6480464	Ritonavir results in increased secretion of CXCL8 protein	CTD	PMID:20884875
Ro 31-8220	multiple interactions	ISO	RGD:1345686	6480464	Ro 31-8220 inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]	CTD	PMID:17000667
rofecoxib	increases expression	ISO	RGD:1345686	6480464	rofecoxib results in increased expression of CXCL8 mRNA	CTD	PMID:16580899
rotenone	multiple interactions	ISO	RGD:1345686	6480464	Rotenone inhibits the reaction [acetylleucyl-leucyl-norleucinal results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12208513, PMID:24316229
rottlerin	multiple interactions	ISO	RGD:1345686	6480464	rottlerin inhibits the reaction [Deferoxamine results in increased expression of CXCL8 protein]	CTD	PMID:17097691
ruthenium red	multiple interactions	ISO	RGD:1345686	6480464	Ruthenium Red inhibits the reaction [Capsaicin results in increased expression of CXCL8 mRNA]	CTD	PMID:16173059
rutin	multiple interactions	ISO	RGD:1345686	6480464	Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:18958421, PMID:21756928
rutin	decreases secretion	ISO	RGD:1345686	6480464	Rutin results in decreased secretion of CXCL8 protein	CTD	PMID:21756928, PMID:21967610
S-butyl-DL-homocysteine (S,R)-sulfoximine	increases secretion	ISO	RGD:1345686	6480464	Buthionine Sulfoximine results in increased secretion of CXCL8 protein	CTD	PMID:20457211
SB 203580	multiple interactions	ISO	RGD:1345686	6480464	SB 203580 affects the reaction [4 more ...	CTD	PMID:10540334 more ...
SB 203580	decreases expression	ISO	RGD:1345686	6480464	SB 203580 results in decreased expression of CXCL8 protein	CTD	PMID:26718265
SB-239063	multiple interactions	ISO	RGD:1345686	6480464	SB 239063 inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:21956143
Scoparone	multiple interactions	ISO	RGD:1345686	6480464	scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA], scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CXCL8 protein]	CTD	PMID:16376386
selenium atom	increases expression	ISO	RGD:1345686	6480464	Selenium results in increased expression of CXCL8 mRNA	CTD	PMID:17293063
selenomethionine	multiple interactions	ISO	RGD:1345686	6480464	Selenomethionine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:14572605
serotonin	affects expression	ISO	RGD:1345686	6480464	Serotonin affects the expression of CXCL8 mRNA	CTD	PMID:15802305
serotonin	affects secretion	ISO	RGD:1345686	6480464	Serotonin affects the secretion of CXCL8 protein	CTD	PMID:15802305
serpentine asbestos	increases expression	ISO	RGD:1345686	6480464	Asbestos, Serpentine results in increased expression of CXCL8 mRNA, Asbestos, Serpentine results in increased expression of CXCL8 protein	CTD	PMID:15790520, PMID:24160326
serpentine asbestos	multiple interactions	ISO	RGD:1345686	6480464	[Asbestos, Serpentine co-treated with 7 more ...	CTD	PMID:18197826
sesquiterpene	multiple interactions	ISO	RGD:1345686	6480464	Sesquiterpenes analog inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]	CTD	PMID:30672058
silicon dioxide	increases expression	ISO	RGD:1345686	6480464	Silicon Dioxide analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:15790520 more ...
silicon dioxide	increases secretion	ISO	RGD:1345686	6480464	Silicon Dioxide analog results in increased secretion of CXCL8 protein, Silicon Dioxide results in increased secretion of CXCL8 protein	CTD	PMID:19428942 more ...
silicon dioxide	multiple interactions	ISO	RGD:1345686	6480464	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Silicon Dioxide analog results in increased secretion of CXCL8 protein] more ...	CTD	PMID:21540303 more ...
silver atom	increases secretion	ISO	RGD:1345686	6480464	Silver analog results in increased secretion of CXCL8 protein, Silver results in increased secretion of CXCL8 protein	CTD	PMID:20064793, PMID:23086748
silver atom	decreases expression	ISO	RGD:1345686	6480464	Silver analog results in decreased expression of CXCL8 mRNA	CTD	PMID:27113704
silver atom	decreases secretion	ISO	RGD:1345686	6480464	Silver analog results in decreased secretion of CXCL8 protein, Silver results in decreased secretion of CXCL8 protein	CTD	PMID:27113704
silver atom	multiple interactions	ISO	RGD:1345686	6480464	[Silver analog co-treated with Quercetin] results in decreased secretion of CXCL8 protein	CTD	PMID:27113704
silver atom	increases expression	ISO	RGD:1345686	6480464	Silver analog results in increased expression of CXCL8 mRNA, Silver results in increased expression of CXCL8 mRNA	CTD	PMID:23086748 more ...
silver(0)	increases secretion	ISO	RGD:1345686	6480464	Silver analog results in increased secretion of CXCL8 protein, Silver results in increased secretion of CXCL8 protein	CTD	PMID:20064793, PMID:23086748
silver(0)	decreases expression	ISO	RGD:1345686	6480464	Silver analog results in decreased expression of CXCL8 mRNA	CTD	PMID:27113704
silver(0)	decreases secretion	ISO	RGD:1345686	6480464	Silver analog results in decreased secretion of CXCL8 protein, Silver results in decreased secretion of CXCL8 protein	CTD	PMID:27113704
silver(0)	multiple interactions	ISO	RGD:1345686	6480464	[Silver analog co-treated with Quercetin] results in decreased secretion of CXCL8 protein	CTD	PMID:27113704
silver(0)	increases expression	ISO	RGD:1345686	6480464	Silver analog results in increased expression of CXCL8 mRNA, Silver results in increased expression of CXCL8 mRNA	CTD	PMID:23086748 more ...
silver(1+)	multiple interactions	ISO	RGD:1345686	6480464	[Silver analog co-treated with Quercetin] results in decreased secretion of CXCL8 protein	CTD	PMID:27113704
silver(1+)	decreases secretion	ISO	RGD:1345686	6480464	Silver analog results in decreased secretion of CXCL8 protein, Silver results in decreased secretion of CXCL8 protein	CTD	PMID:27113704
silver(1+)	decreases expression	ISO	RGD:1345686	6480464	Silver analog results in decreased expression of CXCL8 mRNA	CTD	PMID:27113704
silver(1+)	increases secretion	ISO	RGD:1345686	6480464	Silver analog results in increased secretion of CXCL8 protein, Silver results in increased secretion of CXCL8 protein	CTD	PMID:20064793, PMID:23086748
silver(1+)	increases expression	ISO	RGD:1345686	6480464	Silver analog results in increased expression of CXCL8 mRNA, Silver results in increased expression of CXCL8 mRNA	CTD	PMID:23086748 more ...
silver(1+) nitrate	increases expression	ISO	RGD:1345686	6480464	Silver Nitrate results in increased expression of CXCL8 mRNA	CTD	PMID:20491607
simvastatin	multiple interactions	ISO	RGD:1345686	6480464	geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]] more ...	CTD	PMID:12117737 more ...
simvastatin	decreases expression	ISO	RGD:1345686	6480464	Simvastatin results in decreased expression of CXCL8 mRNA, Simvastatin results in decreased expression of CXCL8 protein	CTD	PMID:12117737 more ...
simvastatin	multiple interactions	EXP		6480464	Simvastatin inhibits the reaction [TNF results in increased expression of CXCL15 mRNA]	CTD	PMID:17178392
simvastatin	decreases secretion	ISO	RGD:1345686	6480464	Simvastatin results in decreased secretion of CXCL8 protein	CTD	PMID:16387846
sirolimus	increases expression	ISO	RGD:1345686	6480464	Sirolimus results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
sirolimus	multiple interactions	ISO	RGD:1345686	6480464	[(+)-JQ1 compound co-treated with Sirolimus] affects the expression of CXCL8 mRNA more ...	CTD	PMID:17606477 more ...
sirtinol	increases expression	ISO	RGD:1345686	6480464	sirtinol results in increased expression of CXCL8 mRNA	CTD	PMID:22385246
sodium arsenite	multiple interactions	ISO	RGD:1345686	6480464	2 more ...	CTD	PMID:10521501 more ...
sodium arsenite	increases expression	ISO	RGD:1345686	6480464	sodium arsenite results in increased expression of CXCL8 mRNA, sodium arsenite results in increased expression of CXCL8 protein	CTD	PMID:10521501 more ...
sodium arsenite	decreases methylation	ISO	RGD:1345686	6480464	sodium arsenite results in decreased methylation of CXCL8 promoter	CTD	PMID:26008221
sodium arsenite	increases secretion	ISO	RGD:1345686	6480464	sodium arsenite results in increased secretion of CXCL8 protein	CTD	PMID:26008221 more ...
sodium aurothiomalate	decreases expression	ISO	RGD:1345686	6480464	Gold Sodium Thiomalate results in decreased expression of CXCL8 mRNA, Gold Sodium Thiomalate results in decreased expression of CXCL8 protein	CTD	PMID:19192274
sodium aurothiosulfate	increases expression	ISO	RGD:1345686	6480464	Gold Sodium Thiosulfate results in increased expression of CXCL8 protein	CTD	PMID:26456670
sodium aurothiosulfate	multiple interactions	ISO	RGD:1345686	6480464	Poly I-C affects the reaction [Gold Sodium Thiosulfate results in increased secretion of CXCL8 protein], TLR3 protein affects the reaction [Gold Sodium Thiosulfate results in increased secretion of CXCL8 protein]	CTD	PMID:25458486
sodium aurothiosulfate	increases secretion	ISO	RGD:1345686	6480464	Gold Sodium Thiosulfate results in increased secretion of CXCL8 protein	CTD	PMID:25458486
sodium bromate	increases expression	ISO	RGD:1345686	6480464	sodium bromate results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
sodium chloride	increases expression	ISO	RGD:1345686	6480464	Sodium Chloride results in increased expression of CXCL8 mRNA	CTD	PMID:11378323, PMID:23634900
sodium dichromate	affects secretion	ISO	RGD:1345686	6480464	sodium bichromate affects the secretion of CXCL8 protein	CTD	PMID:17685462
sodium dichromate	multiple interactions	ISO	RGD:1345686	6480464	sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein]	CTD	PMID:17685462
sodium dodecyl sulfate	decreases expression	ISO	RGD:1345686	6480464	Sodium Dodecyl Sulfate results in decreased expression of CXCL8 mRNA	CTD	PMID:17936526
sodium dodecyl sulfate	increases expression	ISO	RGD:1345686	6480464	Sodium Dodecyl Sulfate results in increased expression of CXCL8 mRNA, Sodium Dodecyl Sulfate results in increased expression of CXCL8 protein	CTD	PMID:12781210 more ...
sodium dodecyl sulfate	decreases secretion	ISO	RGD:1345686	6480464	Sodium Dodecyl Sulfate results in decreased secretion of CXCL8 protein	CTD	PMID:16099135
sodium dodecyl sulfate	increases secretion	ISO	RGD:1345686	6480464	Sodium Dodecyl Sulfate results in increased secretion of CXCL8 protein	CTD	PMID:15679580
sodium dodecyl sulfate	multiple interactions	ISO	RGD:1345686	6480464	IL1A protein affects the reaction [Sodium Dodecyl Sulfate results in increased secretion of CXCL8 protein], TNF protein affects the reaction [Sodium Dodecyl Sulfate results in increased secretion of CXCL8 protein]	CTD	PMID:15679580
sodium nitrite	increases expression	ISO	RGD:1345686	6480464	Sodium Nitrite results in increased expression of CXCL8 mRNA	CTD	PMID:16581224
sodium nitrite	increases secretion	ISO	RGD:1345686	6480464	Sodium Nitrite results in increased secretion of CXCL8 protein	CTD	PMID:16581224
Sodium salicylate	multiple interactions	ISO	RGD:1345686	6480464	Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]	CTD	PMID:10328874
sorbinil	multiple interactions	ISO	RGD:1345686	6480464	sorbinil inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein], sorbinil inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]	CTD	PMID:21334316
sphingosine 1-phosphate	multiple interactions	ISO	RGD:1345686	6480464	1-Butanol inhibits the reaction [sphingosine 1-phosphate results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12039947
sphingosine 1-phosphate	increases expression	ISO	RGD:1345686	6480464	sphingosine 1-phosphate results in increased expression of CXCL8 mRNA, sphingosine 1-phosphate results in increased expression of CXCL8 protein	CTD	PMID:12039947, PMID:19349368
stigmasterol	increases secretion	ISO	RGD:1345686	6480464	Stigmasterol results in increased secretion of CXCL8 protein	CTD	PMID:23454145
styrene	increases expression	ISO	RGD:1345686	6480464	Styrene results in increased expression of CXCL8 protein	CTD	PMID:17993253
succimer	multiple interactions	EXP		6480464	[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CXCL15 mRNA	CTD	PMID:26378955
sulfamethoxazole	increases secretion	ISO	RGD:1345686	6480464	Sulfamethoxazole results in increased secretion of CXCL8 protein	CTD	PMID:22609641
sulfapyridine	decreases secretion	ISO	RGD:1345686	6480464	Sulfapyridine results in decreased secretion of CXCL8 protein	CTD	PMID:12231210
sulfasalazine	multiple interactions	ISO	RGD:1345686	6480464	[Sulfasalazine co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA more ...	CTD	PMID:12135912 more ...
sulfasalazine	decreases expression	ISO	RGD:1345686	6480464	Sulfasalazine results in decreased expression of CXCL8 mRNA	CTD	PMID:12133438 more ...
sulfasalazine	affects secretion	ISO	RGD:1345686	6480464	Sulfasalazine affects the secretion of CXCL8 protein	CTD	PMID:12231210
sulfates	increases expression	ISO	RGD:1345686	6480464	Sulfates results in increased expression of CXCL8 protein	CTD	PMID:18464055
sulforaphane	increases expression	ISO	RGD:1345686	6480464	sulforafan results in increased expression of CXCL8 mRNA	CTD	PMID:26833863
sulforaphane	multiple interactions	ISO	RGD:1345686	6480464	sulforafan inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL8 protein] more ...	CTD	PMID:16905640, PMID:30965051
sulindac sulfide	increases expression	ISO	RGD:1345686	6480464	sulindac sulfide results in increased expression of CXCL8 mRNA	CTD	PMID:16184548
sunitinib	affects response to substance	ISO	RGD:1345686	6480464	CXCL8 polymorphism affects the susceptibility to sunitinib	CTD	PMID:26387812
sunitinib	multiple interactions	ISO	RGD:1345686	6480464	PTEN protein inhibits the reaction [sunitinib results in increased expression of and results in increased secretion of CXCL8 protein] more ...	CTD	PMID:22532600
T-2 Toxin	increases expression	ISO	RGD:1345686	6480464	T-2 Toxin results in increased expression of CXCL8 mRNA, T-2 Toxin results in increased expression of CXCL8 protein	CTD	PMID:21453744
T-2 Toxin	multiple interactions	ISO	RGD:1345686	6480464	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]] more ...	CTD	PMID:21453744
tacrolimus hydrate	multiple interactions	ISO	RGD:1345686	6480464	Tacrolimus inhibits the reaction [cinnamic aldehyde results in increased expression of CXCL8 mRNA], Tacrolimus inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA]	CTD	PMID:20090409
tamoxifen	multiple interactions	ISO	RGD:1345686	6480464	[Tamoxifen co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:17516992 more ...
tamoxifen	increases expression	ISO	RGD:1345686	6480464	Tamoxifen results in increased expression of CXCL8 mRNA	CTD	PMID:15604281
tamoxifen	decreases activity	ISO	RGD:1345686	6480464	Tamoxifen results in decreased activity of CXCL8 protein	CTD	PMID:19401270
tamoxifen	decreases expression	ISO	RGD:1345686	6480464	Tamoxifen results in decreased expression of CXCL8 mRNA, Tamoxifen results in decreased expression of CXCL8 protein	CTD	PMID:16298037, PMID:17516992
telmisartan	decreases expression	ISO	RGD:1345686	6480464	telmisartan metabolite results in decreased expression of CXCL8 mRNA	CTD	PMID:26528891
TEMPO	multiple interactions	ISO	RGD:1345686	6480464	TEMPO inhibits the reaction [Ozone results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:19162161
Temsirolimus	multiple interactions	ISO	RGD:1345686	6480464	temsirolimus inhibits the reaction [sunitinib results in increased expression of and results in increased secretion of CXCL8 protein]	CTD	PMID:22532600
tenofovir disoproxil fumarate	increases expression	ISO	RGD:1345686	6480464	Tenofovir results in increased expression of CXCL8 mRNA	CTD	PMID:24205323
tenofovir disoproxil fumarate	multiple interactions	ISO	RGD:1345686	6480464	Tenofovir results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:24205323
terbinafine	multiple interactions	ISO	RGD:1345686	6480464	terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA], U 0126 inhibits the reaction [terbinafine results in increased expression of CXCL8 protein]	CTD	PMID:20816994, PMID:23688403
terbinafine	increases expression	ISO	RGD:1345686	6480464	terbinafine results in increased expression of CXCL8 protein	CTD	PMID:20816994
terbutaline	multiple interactions	ISO	RGD:1345686	6480464	[Terbutaline results in increased abundance of Cyclic AMP] which results in increased expression of CXCL8 protein more ...	CTD	PMID:9258252
tert-butyl hydroperoxide	multiple interactions	ISO	RGD:1345686	6480464	1 more ...	CTD	PMID:17129690 more ...
tert-butyl hydroperoxide	affects expression	ISO	RGD:1345686	6480464	tert-Butylhydroperoxide affects the expression of CXCL8 mRNA	CTD	PMID:23410634
tert-butyl hydroperoxide	increases secretion	ISO	RGD:1345686	6480464	tert-Butylhydroperoxide results in increased secretion of CXCL8 protein	CTD	PMID:17129690, PMID:29935159
tert-butyl hydroperoxide	increases expression	ISO	RGD:1345686	6480464	tert-Butylhydroperoxide results in increased expression of CXCL8 mRNA, tert-Butylhydroperoxide results in increased expression of CXCL8 protein	CTD	PMID:15336504 more ...
testosterone	multiple interactions	ISO	RGD:1345686	6480464	[Lipopolysaccharides co-treated with Testosterone] results in increased secretion of CXCL8 protein, [Testosterone co-treated with Calcitriol] results in increased expression of CXCL8 mRNA	CTD	PMID:21592394, PMID:27239218
testosterone	increases expression	ISO	RGD:1345686	6480464	Testosterone results in increased expression of CXCL8 mRNA	CTD	PMID:21592394
tetrachloropalladate(2-)	increases secretion	ISO	RGD:1345686	6480464	tetrachloropalladium results in increased secretion of CXCL8 protein	CTD	PMID:23692033
tetrachloropalladate(2-)	multiple interactions	ISO	RGD:1345686	6480464	TLR4 protein affects the reaction [tetrachloropalladium results in increased secretion of CXCL8 protein]	CTD	PMID:23692033
tetradecane	multiple interactions	ISO	RGD:1345686	6480464	n-tetradecane results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:19720135
tetraphene	multiple interactions	ISO	RGD:1345686	6480464	[benz(a)anthracene co-treated with TNF protein] results in increased expression of CXCL8 mRNA	CTD	PMID:23396138
tetraphene	increases expression	ISO	RGD:1345686	6480464	benz(a)anthracene results in increased expression of CXCL8 mRNA	CTD	PMID:25433334
thalidomide	multiple interactions	ISO	RGD:1345686	6480464	Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA], Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]	CTD	PMID:15687330
thalidomide	decreases activity	ISO	RGD:1345686	6480464	Thalidomide results in decreased activity of CXCL8 protein	CTD	PMID:17557286
thapsigargin	increases expression	ISO	RGD:1345686	6480464	Thapsigargin results in increased expression of CXCL8 mRNA	CTD	PMID:18951912, PMID:29453283
theophylline	decreases expression	ISO	RGD:1345686	6480464	Theophylline results in decreased expression of CXCL8 protein	CTD	PMID:12016098
theophylline	multiple interactions	ISO	RGD:1345686	6480464	[Dexamethasone co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein] more ...	CTD	PMID:12070353, PMID:15337792
thimerosal	multiple interactions	ISO	RGD:1345686	6480464	Acetylcysteine inhibits the reaction [Thimerosal results in increased secretion of CXCL8 protein], Glutathione inhibits the reaction [Thimerosal results in increased secretion of CXCL8 protein]	CTD	PMID:20457211
thimerosal	increases secretion	ISO	RGD:1345686	6480464	Thimerosal results in increased secretion of CXCL8 protein	CTD	PMID:18495191 more ...
thioacetamide	increases secretion	ISO	RGD:1345686	6480464	Thioacetamide results in increased secretion of CXCL8 protein	CTD	PMID:27605418
thiophenes	multiple interactions	ISO	RGD:1345686	6480464	Thiophenes analog promotes the reaction [Tretinoin results in increased expression of CXCL8 mRNA]	CTD	PMID:16140955
thiourea	multiple interactions	ISO	RGD:1345686	6480464	Thiourea inhibits the reaction [cadmium acetate results in increased secretion of CXCL8 protein] more ...	CTD	PMID:26160521, PMID:27427241
thiram	increases expression	ISO	RGD:1345686	6480464	Thiram results in increased expression of CXCL8 mRNA	CTD	PMID:21920952, PMID:27965148
thiram	increases secretion	ISO	RGD:1345686	6480464	Thiram results in increased secretion of CXCL8 protein	CTD	PMID:18494145, PMID:19878716
thiram	multiple interactions	ISO	RGD:1345686	6480464	SB 203580 affects the reaction [Thiram results in increased secretion of CXCL8 protein]	CTD	PMID:18494145
thymidine	multiple interactions	ISO	RGD:1345686	6480464	[Thymidine co-treated with TYMP protein] results in increased secretion of CXCL8 protein, Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased secretion of CXCL8 protein]	CTD	PMID:11103787
thymine	multiple interactions	ISO	RGD:1345686	6480464	Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased secretion of CXCL8 protein]	CTD	PMID:11103787
titanium atom	multiple interactions	ISO	RGD:1345686	6480464	benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Titanium results in increased secretion of CXCL8 protein], Cytochalasin D inhibits the reaction [Titanium results in increased secretion of CXCL8 protein]	CTD	PMID:16392133
titanium atom	increases secretion	ISO	RGD:1345686	6480464	Titanium results in increased secretion of CXCL8 protein	CTD	PMID:16392133
titanium atom	increases expression	ISO	RGD:1345686	6480464	Titanium results in increased expression of CXCL8 mRNA	CTD	PMID:16392133
titanium dioxide	multiple interactions	EXP		6480464	Vitamin E inhibits the reaction [titanium dioxide results in increased secretion of CXCL8 protein]	CTD	PMID:30626778
titanium dioxide	increases expression	ISO	RGD:1345686	6480464	titanium dioxide results in increased expression of CXCL8 mRNA	CTD	PMID:27060086
titanium dioxide	increases secretion	ISO	RGD:1345686	6480464	titanium dioxide results in increased secretion of CXCL8 protein	CTD	PMID:20005940 more ...
titanium dioxide	increases expression	EXP		6480464	titanium dioxide results in increased expression of CXCL15 mRNA	CTD	PMID:23557971
titanium dioxide	affects expression	ISO	RGD:1345686	6480464	titanium dioxide affects the expression of CXCL8 mRNA	CTD	PMID:19695317
titanium dioxide	multiple interactions	ISO	RGD:1345686	6480464	[Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CXCL8 protein more ...	CTD	PMID:21341804, PMID:30711708
titanium dioxide	increases secretion	EXP		6480464	titanium dioxide results in increased secretion of CXCL8 protein	CTD	PMID:30626778
toluene	increases expression	ISO	RGD:1345686	6480464	Toluene results in increased expression of CXCL8 mRNA	CTD	PMID:20359517
toluene	multiple interactions	EXP		6480464	[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in increased expression of CXCL15 protein	CTD	PMID:24733833
toluene 2,4-diisocyanate	multiple interactions	ISO	RGD:1345686	6480464	[Tetradecanoylphorbol Acetate co-treated with Toluene 2 more ...	CTD	PMID:14676436 more ...
trans-caffeic acid	multiple interactions	ISO	RGD:1345686	6480464	caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA], caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	CTD	PMID:17636245
trans-isoeugenol	multiple interactions	ISO	RGD:1345686	6480464	[Indomethacin co-treated with isoeugenol] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:21284934, PMID:21969073
trans-isoeugenol	increases expression	ISO	RGD:1345686	6480464	isoeugenol results in increased expression of CXCL8 mRNA, isoeugenol results in increased expression of CXCL8 protein	CTD	PMID:21284934 more ...
trans-piceid	multiple interactions	ISO	RGD:1345686	6480464	[polydatin co-treated with TGFA protein] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:21756928
trans-piceid	increases secretion	ISO	RGD:1345686	6480464	polydatin results in increased secretion of CXCL8 protein	CTD	PMID:21756928, PMID:21967610
trans-piceid	decreases expression	ISO	RGD:1345686	6480464	polydatin results in decreased expression of CXCL8 mRNA	CTD	PMID:21756928, PMID:21967610
triacetin	multiple interactions	ISO	RGD:1345686	6480464	[Biofuels co-treated with Triacetin] results in increased secretion of CXCL8 protein	CTD	PMID:30738890
tributylstannane	decreases expression	ISO	RGD:1345686	6480464	tributyltin results in decreased expression of CXCL8 mRNA	CTD	PMID:26314263
tricetin	multiple interactions	ISO	RGD:1345686	6480464	tricetin inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]	CTD	PMID:17884996
trichloroacetic acid	multiple interactions	ISO	RGD:1345686	6480464	Trichloroacetic Acid results in decreased expression of and results in decreased secretion of CXCL8 protein	CTD	PMID:29953848
trichloroethene	increases expression	ISO	RGD:1345686	6480464	Trichloroethylene results in increased expression of CXCL8 mRNA	CTD	PMID:20359517
trichostatin A	multiple interactions	ISO	RGD:1345686	6480464	trichostatin A promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CXCL8 protein], trichostatin A promotes the reaction [sodium arsenite results in increased expression of CXCL8 protein]	CTD	PMID:12470611, PMID:26008221
trichostatin A	increases expression	ISO	RGD:1345686	6480464	trichostatin A results in increased expression of CXCL8 mRNA	CTD	PMID:24935251
tridecane	increases expression	ISO	RGD:1345686	6480464	tridecane results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
tridecane	multiple interactions	ISO	RGD:1345686	6480464	tridecane results in increased expression of and results in increased secretion of CXCL8 protein	CTD	PMID:19720135
triethanolamine	increases expression	ISO	RGD:1345686	6480464	triethanolamine results in increased expression of CXCL8 mRNA	CTD	PMID:29594315
triprolidine	decreases response to substance	ISO	RGD:1345686	6480464	Triprolidine results in decreased susceptibility to CXCL8 protein	CTD	PMID:7522859
triprolidine	multiple interactions	ISO	RGD:1345686	6480464	HRH1 protein promotes the reaction [Triprolidine results in decreased susceptibility to CXCL8 protein]	CTD	PMID:7522859
Triptolide	multiple interactions	ISO	RGD:1345686	6480464	triptolide inhibits the reaction [deoxynivalenol results in increased secretion of CXCL8 protein], triptolide inhibits the reaction [TAC1 protein results in increased expression of CXCL8 protein]	CTD	PMID:20348278, PMID:20633634
troglitazone	increases expression	ISO	RGD:1345686	6480464	troglitazone results in increased expression of CXCL8 mRNA	CTD	PMID:19140230
troglitazone	decreases expression	ISO	RGD:1345686	6480464	troglitazone results in decreased expression of CXCL8 mRNA	CTD	PMID:20846491, PMID:25572481
tubocurarine	multiple interactions	ISO	RGD:1345686	6480464	Tubocurarine inhibits the reaction [Nicotine promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]], Tubocurarine inhibits the reaction [Nicotine promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]	CTD	PMID:22119045
tyrphostin AG 1478	multiple interactions	ISO	RGD:1345686	6480464	RTKI cpd affects the reaction [Capsaicin results in increased secretion of CXCL8 protein] more ...	CTD	PMID:15247267 more ...
tyrphostin AG 1478	decreases expression	ISO	RGD:1345686	6480464	RTKI cpd results in decreased expression of CXCL8 protein	CTD	PMID:26718265
ubiquinones	multiple interactions	ISO	RGD:1345686	6480464	[Ubiquinone co-treated with Niacin co-treated with Riboflavin] promotes the reaction [Tamoxifen results in decreased expression of CXCL8 protein]	CTD	PMID:17516992
UDP	multiple interactions	ISO	RGD:1345686	6480464	[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein more ...	CTD	PMID:20083671
undecanal	increases expression	ISO	RGD:1345686	6480464	undecanal analog results in increased expression of CXCL8 mRNA	CTD	PMID:27965148
urethane	decreases expression	ISO	RGD:1345686	6480464	Urethane results in decreased expression of CXCL8 mRNA	CTD	PMID:28818685
ursodeoxycholic acid	multiple interactions	ISO	RGD:1345686	6480464	Ursodeoxycholic Acid analog inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein], Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CXCL8 mRNA]]	CTD	PMID:21146893
valproic acid	increases expression	ISO	RGD:1345686	6480464	Valproic Acid results in increased expression of CXCL8 mRNA	CTD	PMID:24935251
valsartan	multiple interactions	ISO	RGD:1345686	6480464	Valsartan inhibits the reaction [sodium arsenite results in increased secretion of CXCL8 protein]	CTD	PMID:28973481
vanadium atom	increases expression	ISO	RGD:1345686	6480464	Vanadium results in increased expression of CXCL8 mRNA, Vanadium results in increased expression of CXCL8 protein	CTD	PMID:18464055, PMID:9344885
vanadium(0)	increases expression	ISO	RGD:1345686	6480464	Vanadium results in increased expression of CXCL8 mRNA, Vanadium results in increased expression of CXCL8 protein	CTD	PMID:18464055, PMID:9344885
vanadium(3+)	increases expression	ISO	RGD:1345686	6480464	Vanadium results in increased expression of CXCL8 mRNA, Vanadium results in increased expression of CXCL8 protein	CTD	PMID:18464055, PMID:9344885
vanadyl sulfate	increases secretion	ISO	RGD:1345686	6480464	vanadyl sulfate results in increased secretion of CXCL8 protein	CTD	PMID:9728050
vanadyl sulfate	increases expression	ISO	RGD:1345686	6480464	vanadyl sulfate results in increased expression of CXCL8 mRNA, vanadyl sulfate results in increased expression of CXCL8 protein	CTD	PMID:10521501 more ...
vanadyl sulfate	multiple interactions	ISO	RGD:1345686	6480464	NFKBIA protein mutant form inhibits the reaction [vanadyl sulfate results in increased expression of CXCL8 mRNA]	CTD	PMID:10521501
vanillin	increases expression	ISO	RGD:1345686	6480464	vanillin results in increased expression of CXCL8 mRNA	CTD	PMID:20491607, PMID:21920952
Verbascoside	decreases expression	ISO	RGD:1345686	6480464	acteoside results in decreased expression of CXCL8 mRNA	CTD	PMID:21371465 more ...
Verbascoside	multiple interactions	ISO	RGD:1345686	6480464	[acteoside co-treated with TGFA protein] results in increased expression of CXCL8 mRNA more ...	CTD	PMID:21756928, PMID:21967610
Verbascoside	decreases secretion	ISO	RGD:1345686	6480464	acteoside results in decreased secretion of CXCL8 protein	CTD	PMID:21756928 more ...
vincaleukoblastine	affects response to substance	ISO	RGD:1345686	6480464	CXCL8 protein affects the susceptibility to Vinblastine	CTD	PMID:16217747
vincaleukoblastine	multiple interactions	ISO	RGD:1345686	6480464	Paclitaxel inhibits the reaction [Vinblastine results in increased stability of CXCL8 mRNA]	CTD	PMID:16499908
vincaleukoblastine	increases stability	ISO	RGD:1345686	6480464	Vinblastine results in increased stability of CXCL8 mRNA	CTD	PMID:16499908
vincristine	increases expression	ISO	RGD:1345686	6480464	Vincristine results in increased expression of CXCL8 mRNA	CTD	PMID:23649840
vitamin D	multiple interactions	ISO	RGD:1345686	6480464	Vitamin D inhibits the reaction [Dust results in increased secretion of CXCL8 protein]	CTD	PMID:23281135
vitamin E	multiple interactions	ISO	RGD:1345686	6480464	[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein] more ...	CTD	PMID:16076765 more ...
vitamin E	multiple interactions	EXP		6480464	Vitamin E inhibits the reaction [titanium dioxide results in increased secretion of CXCL8 protein]	CTD	PMID:30626778
vorinostat	increases expression	ISO	RGD:1345686	6480464	vorinostat results in increased expression of CXCL8 mRNA	CTD	PMID:15300209 more ...
vorinostat	multiple interactions	ISO	RGD:1345686	6480464	BAY 11-7085 inhibits the reaction [vorinostat results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:15300209 more ...
vorinostat	decreases expression	ISO	RGD:1345686	6480464	vorinostat results in decreased expression of CXCL8 protein	CTD	PMID:19509267
warfarin	multiple interactions	ISO	RGD:1345686	6480464	[Warfarin co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA	CTD	PMID:29594315
withaferin A	multiple interactions	ISO	RGD:1345686	6480464	withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA]	CTD	PMID:20438634
wortmannin	multiple interactions	ISO	RGD:1345686	6480464	wortmannin inhibits the reaction [CXCL8 protein results in increased activity of CXCR2 protein] more ...	CTD	PMID:11978798 more ...
zafirlukast	multiple interactions	ISO	RGD:1345686	6480464	zafirlukast inhibits the reaction [[Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein], zafirlukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein]	CTD	PMID:18704935, PMID:20083671
zearalenone	increases expression	ISO	RGD:1345686	6480464	Zearalenone results in increased expression of CXCL8 mRNA	CTD	PMID:27757495
zileuton	multiple interactions	ISO	RGD:1345686	6480464	Leukotriene B4 inhibits the reaction [zileuton inhibits the reaction [Histamine results in increased expression of CXCL8 protein]] more ...	CTD	PMID:9609743
zinc acetate	multiple interactions	ISO	RGD:1345686	6480464	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein] more ...	CTD	PMID:24080332
zinc acetate	increases expression	ISO	RGD:1345686	6480464	Zinc Acetate results in increased expression of CXCL8 protein	CTD	PMID:24080332
zinc acetate	increases secretion	ISO	RGD:1345686	6480464	Zinc Acetate results in increased secretion of CXCL8 protein	CTD	PMID:21974847
zinc atom	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Zinc results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12812920 more ...
zinc atom	decreases expression	ISO	RGD:1345686	6480464	Zinc deficiency results in decreased expression of CXCL8 protein	CTD	PMID:12812920
zinc atom	increases expression	ISO	RGD:1345686	6480464	Zinc analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:16373669 more ...
zinc dichloride	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein] more ...	CTD	PMID:27427241
zinc dichloride	increases secretion	ISO	RGD:1345686	6480464	zinc chloride results in increased secretion of CXCL8 protein	CTD	PMID:19428942 more ...
zinc dichloride	increases expression	ISO	RGD:1345686	6480464	zinc chloride results in increased expression of CXCL8 mRNA	CTD	PMID:19428942 more ...
zinc oxide	multiple interactions	ISO	RGD:1345686	6480464	[titanium dioxide co-treated with Zinc Oxide] results in increased expression of CXCL8 protein more ...	CTD	PMID:20194077, PMID:21341804
zinc oxide	increases expression	ISO	RGD:1345686	6480464	Zinc Oxide results in increased expression of CXCL8 mRNA, Zinc Oxide results in increased expression of CXCL8 protein	CTD	PMID:20194077, PMID:21341804
zinc sulfate	multiple interactions	ISO	RGD:1345686	6480464	Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:16606632, PMID:22722935
zinc sulfate	decreases expression	ISO	RGD:1345686	6480464	Zinc Sulfate results in decreased expression of CXCL8 mRNA	CTD	PMID:22722935
zinc sulfate	increases secretion	ISO	RGD:1345686	6480464	Zinc Sulfate results in increased secretion of CXCL8 protein	CTD	PMID:9728050
zinc(0)	multiple interactions	ISO	RGD:1345686	6480464	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Zinc results in increased expression of CXCL8 mRNA] more ...	CTD	PMID:12812920 more ...
zinc(0)	increases expression	ISO	RGD:1345686	6480464	Zinc analog results in increased expression of CXCL8 mRNA more ...	CTD	PMID:16373669 more ...
zinc(0)	decreases expression	ISO	RGD:1345686	6480464	Zinc deficiency results in decreased expression of CXCL8 protein	CTD	PMID:12812920
zoledronic acid	increases expression	ISO	RGD:1345686	6480464	zoledronic acid results in increased expression of CXCL8 mRNA	CTD	PMID:24714768
zomepirac	increases expression	ISO	RGD:1345686	6480464	zomepirac metabolite results in increased expression of CXCL8	CTD	PMID:29154782

Gene Ontology Annotations

Biological Process

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
antimicrobial humoral immune response mediated by antimicrobial peptide		IBA	MGI:MGI:1888711 more ...	2290270		GO_Central	PMID:21873635
cellular response to lipopolysaccharide		IBA	PANTHER:PTN000021269 more ...	2290270		GO_Central	PMID:21873635
chemokine-mediated signaling pathway		IBA	PANTHER:PTN000021269 more ...	2290270		GO_Central	PMID:21873635
chemotaxis		IDA		2290270		MGI	MGI:MGI:1353826, PMID:10714680
defense response		IEA	InterPro:IPR033899	2290270		UniProtKB	GO_REF:0000002, MGI:MGI:2152098
hemopoiesis		IDA		2290270		MGI	MGI:MGI:1353826, PMID:10714680
immune response		IBA	PANTHER:PTN000021269 more ...	2290270		GO_Central	PMID:21873635
inflammatory response		IBA	MGI:MGI:1339941 more ...	2290270		GO_Central	PMID:21873635
inflammatory response		IDA		2290270		MGI	MGI:MGI:1335723, PMID:10228029
leukocyte chemotaxis		IBA	PANTHER:PTN000021269 more ...	2290270		GO_Central	PMID:21873635
neutrophil chemotaxis		IBA	MGI:MGI:1339941 more ...	2290270		GO_Central	PMID:21873635
neutrophil chemotaxis		IDA		2290270		MGI	MGI:MGI:1335723, PMID:10228029

Cellular Component

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
extracellular region		IDA		2290270		MGI	MGI:MGI:1335723, PMID:10228029
extracellular space		IBA	MGI:MGI:108068 more ...	2290270		GO_Central	PMID:21873635

Molecular Function

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
chemokine activity		IBA	MGI:MGI:1339941 more ...	2290270		GO_Central	PMID:21873635
chemokine activity		IDA		2290270		MGI	MGI:MGI:1335723 more ...
cytokine activity		IEA	UniProtKB-KW:KW-0202	2290270		UniProtKB	GO_REF:0000004, MGI:MGI:1354194

Molecular Pathway Annotations

Imported Annotations - PID (archival)

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
chemokine (C-X-C motif) ligand 8 signaling pathway		ISO	RGD:1345686	6484113		PID	PID:200136
syndecan signaling pathway		ISO	RGD:1345686	6484113		PID	PID:200198
syndecan signaling pathway		ISO	RGD:1345686	6484113		PID	PID:200192

Phenotype Annotations

Mammalian Phenotype

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
decreased neutrophil cell number		IAGP		5509061		MGI	PMID:11207292
increased susceptibility to bacterial infection		IAGP		5509061		MGI	PMID:11207292

Disease Annotations

	adenocarcinoma (ISO)
	alcoholic hepatitis (ISO)
	allergic hypersensitivity disease (EXP)
	Bacterial Eye Infections (ISO)
	Barrett's esophagus (ISO)
	Behcet's disease (ISO)
	Breast Neoplasms (ISO)
	bullous pemphigoid (EXP,ISO)
	Cachexia (ISO)
	Cardiotoxicity (ISO)
	Cell Transformation, Neoplastic (ISO)
	cholestasis (ISO)
	chronic obstructive pulmonary disease (ISO)
	Colorectal Neoplasms (ISO)
	congestive heart failure (ISO)
	cutaneous leishmaniasis (ISO)
	Down syndrome (ISO)
	Edema (ISO)
	Endometrial Neoplasms (ISO)
	fatty liver disease (ISO)

	Fever (ISO)
	gastroesophageal reflux disease (ISO)
	glioblastoma multiforme (ISO)
	glomerulonephritis (ISO)
	hepatocellular carcinoma (ISO)
	Hyperalgesia (ISO)
	Inflammation (ISO)
	intermediate coronary syndrome (ISO)
	Intractable Pain (ISO)
	keratitis (ISO)
	lichen disease (ISO)
	liver cirrhosis (EXP)
	lung non-small cell carcinoma (ISO)
	malignant mesothelioma (ISO)
	oral submucous fibrosis (ISO)
	Ovarian Neoplasms (ISO)
	pancreatic cancer (ISO)
	peptic esophagitis (ISO)
	Pneumococcal Pneumonia (ISO)
	pneumonia (EXP)

	Postherpetic Neuralgia (ISO)
	Prostatic Neoplasms (ISO)
	psoriatic arthritis (ISO)
	pulmonary fibrosis (ISO)
	pulmonary hypertension (ISO)
	Reperfusion Injury (ISO)
	rheumatoid arthritis (ISO)
	Salmonella Infections, Animal (ISO)
	squamous cell carcinoma (ISO)
	Staphylococcal Infections (ISO)
	Stomach Neoplasms (ISO)
	Thyroid Neoplasms (ISO)
	Tobacco Use Disorder (ISO)
	ulcerative colitis (ISO)
	urinary bladder cancer (ISO)
	visceral leishmaniasis (ISO)
	Wilson disease (ISO)

Gene-Chemical Interaction Annotations

	(+)-alpha-tocopherol (ISO)
	(+)-catechin (ISO)
	(-)-anisomycin (ISO)
	(-)-demecolcine (ISO)
	(-)-epigallocatechin 3-gallate (ISO)
	(-)-selegiline (ISO)
	(2-trans,6-trans)-farnesol (ISO)
	(24S)-24-hydroxycholesterol (ISO)
	(25R)-cholest-5-ene-3beta,26-diol (ISO)
	(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid (ISO)
	(E)-cinnamyl alcohol (ISO)
	(E)-roxithromycin (ISO)
	(R)-mevalonic acid (ISO)
	(R)-noradrenaline (ISO)
	(R)-pantothenic acid (ISO)
	(S)-colchicine (ISO)
	(S)-naringenin (ISO)
	(S)-nicotine (ISO)
	1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO)
	1,10-phenanthroline (ISO)
	1,2,3-Trichloropropane (ISO)
	1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (ISO)
	1,2-dipalmitoylphosphatidylcholine (ISO)
	1,2-Naphthoquinone (ISO)
	1,3-benzothiazole-2-thiol (ISO)
	1,4-benzoquinone (ISO)
	1,4-naphthoquinone (ISO)
	1,4-phenylenediamine (ISO)
	1-chloro-2,4-dinitrobenzene (ISO)
	1-fluoro-2,4-dinitrobenzene (ISO)
	1-nitronaphthalene (ISO)
	1-nitropyrene (ISO)
	1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine (ISO)
	14-Deoxy-11,12-didehydroandrographolide (ISO)
	15-deoxy-Delta(12,14)-prostaglandin J2 (ISO)
	17beta-estradiol (EXP,ISO)
	17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)
	17beta-hydroxy-5alpha-androstan-3-one (ISO)
	2,2',4,4',5,5'-hexachlorobiphenyl (ISO)
	2,2',4,4'-Tetrabromodiphenyl ether (ISO)
	2,2'-bipyridine (ISO)
	2,2,2-tetramine (ISO)
	2,3,3',4,4',5,5'-Heptachlorobiphenyl (ISO)
	2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)
	2,4,6-trinitrobenzenesulfonic acid (ISO)
	2,4-di-tert-butylphenol (ISO)
	2,4-diaminotoluene (ISO)
	2,4-dinitroiodobenzene (ISO)
	2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione (ISO)
	2-acetyl-1-alkyl-sn-glycero-3-phosphocholine (ISO)
	2-amino-2-deoxy-D-glucopyranose (ISO)
	2-aminophenol (ISO)
	2-aminopurine (ISO)
	2-arachidonoylglycerol (ISO)
	2-bromo-2-(bromomethyl)pentanedinitrile (ISO)
	2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one (ISO)
	2-Ethylhexyl acrylate (ISO)
	2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID (ISO)
	2-hydroxypropyl methacrylate (ISO)
	2-methylcholine (ISO)
	2-methylserotonin (ISO)
	2-nitrofluorene (ISO)
	2-nitronaphthalene (ISO)
	2-tert-butylhydroquinone (ISO)
	2-trans,6-trans,10-trans-geranylgeranyl diphosphate (ISO)
	24,25-Dihydroxyvitamin D (ISO)
	25-hydroxycholesterol (ISO)
	26-hydroxycholesterol (ISO)
	3',5'-cyclic AMP (ISO)
	3,3',4',5-tetrachlorosalicylanilide (ISO)
	3,3',4,4',5-pentachlorobiphenyl (ISO)
	3,3',5,5'-tetrabromobisphenol A (ISO)
	3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid (ISO)
	3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione (ISO)
	3-aminophenol (ISO)
	3-isobutyl-1-methyl-7H-xanthine (ISO)
	3-methyladenine (ISO)
	3-Nitrofluoranthene (ISO)
	4'-hydroxydiclofenac (ISO)
	4,4'-sulfonyldiphenol (ISO)
	4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)
	4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (ISO)
	4-methoxyacetophenone (ISO)
	4-nitroaniline (ISO)
	4-nitrobenzyl bromide (ISO)
	4-nitrophenol (ISO)
	4-phenylbutyric acid (ISO)
	5-chloro-7-iodoquinolin-8-ol (ISO)
	5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (ISO)
	5-fluorouracil (ISO)
	6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (ISO)
	6-Nitrochrysene (ISO)
	6alpha-methylprednisolone (ISO)
	7-ketocholesterol (ISO)
	7alpha-hydroxycholesterol (ISO)
	8-bromo-3',5'-cyclic AMP (ISO)
	8-OH-DPAT (ISO)
	9,10-phenanthroquinone (ISO)
	AACOCF3 (EXP,ISO)
	abietic acid (ISO)
	acenaphthene (ISO)
	acenaphthylene (ISO)
	acetaldehyde (ISO)
	acetate ester (ISO)
	acetic anhydride (ISO)
	acetoacetic acid (ISO)
	acetylleucyl-leucyl-norleucinal (ISO)
	acetylsalicylic acid (ISO)
	acrolein (ISO)
	actinomycin D (ISO)
	adenine (ISO)
	adenosine (ISO)
	adenosine 5'-[gamma-thio]triphosphate (ISO)
	aflatoxin B1 (ISO)
	AICA ribonucleotide (ISO)
	albendazole (ISO)
	albuterol (ISO)
	aldehydo-D-glucosamine (ISO)
	aldehydo-D-glucose (ISO)
	alexidine (ISO)
	all-trans-retinoic acid (ISO)
	allopurinol (ISO)
	alloxanthine (ISO)
	alpha-D-galactose (ISO)
	alpha-hexylcinnamaldehyde (ISO)
	alpha-naphthoflavone (ISO)
	aluminium atom (ISO)
	aluminium hydroxide (ISO)
	aluminium oxide (ISO)
	aluminium(0) (ISO)
	aluminium(3+) (ISO)
	AM-251 (ISO)
	amidotrizoic acid (ISO)
	amiloride (ISO)
	amiodarone (ISO)
	ammonium hexachloroplatinate (ISO)
	amorolfine (ISO)
	amoxicillin (ISO)
	amphibole asbestos (ISO)
	amphotericin B (ISO)
	ampicillin (ISO)
	andrographolide (EXP)
	aniline (ISO)
	anthra[1,9-cd]pyrazol-6(2H)-one (ISO)
	anthracen-2-amine (ISO)
	anthracene (ISO)
	anthracene-1,8,9-triol (ISO)
	antimycin A (ISO)
	antirheumatic drug (ISO)
	apocynin (ISO)
	arachidonic acid (EXP,ISO)
	arecoline (ISO)
	Aroclor 1254 (ISO)
	arsane (ISO)
	arsenic acid (ISO)
	arsenic atom (ISO)
	arsenic(3+) (ISO)
	arsenite(3-) (ISO)
	asbestos (ISO)
	aspalathin (ISO)
	asperentin (EXP)
	atorvastatin calcium (ISO)
	atrazine (EXP)
	Augmentin (ISO)
	avobenzone (ISO)
	azathioprine (ISO)
	aziridines (ISO)
	azithromycin (ISO)
	Bandrowski's base (ISO)
	beclomethasone (ISO)
	belinostat (ISO)
	benomyl (ISO)
	benzalkonium chloride (ISO)
	benzene (EXP,ISO)
	benzene-1,2,4-triol (ISO)
	benzethonium chloride (ISO)
	benzo[a]pyrene (EXP,ISO)
	benzo[a]pyrene diol epoxide I (ISO)
	benzo[b]fluoranthene (ISO)
	benzo[c]phenanthrene (ISO)
	Benzo[k]fluoranthene (ISO)
	benzofurans (ISO)
	benzoic acid (ISO)
	Benzoyl peroxide (ISO)
	benzyl benzoate (ISO)
	benzyl bromide (ISO)
	benzylpenicillin (ISO)
	berberine (ISO)
	beta-carotene (ISO)
	beta-D-glucosamine (ISO)
	betamethasone (ISO)
	bezafibrate (ISO)
	bilirubin IXalpha (ISO)
	biochanin A (ISO)
	bis(2-chloroethyl) sulfide (ISO)
	bis(2-ethylhexyl) phthalate (ISO)
	bisphenol A (ISO)
	Bisphenol A diglycidyl ether (ISO)
	Bisphenol A glycidylmethacrylate (ISO)
	bleomycin A2 (ISO)
	bortezomib (ISO)
	bosentan (ISO)
	Brevetoxin B (ISO)
	bromobenzene (ISO)
	bucladesine (ISO)
	budesonide (ISO)
	butan-1-ol (ISO)
	butanal (ISO)
	butane-2,3-dione (ISO)
	butenafine (ISO)
	Butylbenzyl phthalate (ISO)
	butyric acid (ISO)
	cadmium atom (ISO)
	cadmium dichloride (ISO)
	cadmium sulfate (ISO)
	caffeine (ISO)
	Calcimycin (ISO)
	calcitriol (ISO)
	calcium atom (ISO)
	calcium(0) (ISO)
	camptothecin (ISO)
	candesartan (ISO)
	canertinib (ISO)
	capsaicin (ISO)
	capsazepine (ISO)
	carazolol (ISO)
	carbamate ester (ISO)
	carbamazepine (ISO)
	carbon nanotube (EXP,ISO)
	carrageenan (ISO)
	catechin (ISO)
	catechol (ISO)
	celecoxib (ISO)
	cephaeline (ISO)
	ceric oxide (ISO)
	cerium trichloride (EXP)
	cerivastatin (ISO)
	cetirizine (ISO)
	cetylpyridinium (ISO)
	chelerythrine (ISO)
	chlorendic acid (ISO)
	chlorobenzene (ISO)
	chloroform (ISO)
	chloromethylisothiazolinone (ISO)
	chloropicrin (ISO)
	chloroprene (EXP)
	chloroquine (ISO)
	chlorpromazine (ISO)
	chlorpyrifos (ISO)
	cholesterol (ISO)
	chromium atom (ISO)
	chromium trioxide (ISO)
	chromium(3+) (ISO)
	chromium(3+) trichloride (ISO)

	chromium(6+) (ISO)
	chrysene (ISO)
	chrysin (ISO)
	chrysin 5,7-dimethyl ether (ISO)
	cimetidine (ISO)
	cinnamyl alcohol (ISO)
	ciprofloxacin (ISO)
	cis-caffeic acid (ISO)
	cisplatin (EXP,ISO)
	citral (ISO)
	cladribine (ISO)
	clarithromycin (ISO)
	clenbuterol (ISO)
	clonazepam (ISO)
	clonidine (ISO)
	clonidine (amino form) (ISO)
	clonidine (imino form) (ISO)
	clotrimazole (ISO)
	cobalt atom (ISO)
	cobalt dichloride (ISO)
	cobalt(2+) (ISO)
	cobalt(2+) sulfate (ISO)
	cocaine (ISO)
	codeine (ISO)
	Colforsin dapropate hydrochloride (EXP,ISO)
	conjugated linoleic acid (ISO)
	copper atom (ISO)
	copper(0) (ISO)
	copper(2+) (ISO)
	copper(II) chloride (ISO)
	copper(II) sulfate (ISO)
	cortisol (ISO)
	crocidolite asbestos (ISO)
	crotonaldehyde (ISO)
	CU-O LINKAGE (ISO)
	curcumin (ISO)
	cyanuric chloride (ISO)
	cycloheximide (ISO)
	cyclophosphamide (ISO)
	cyclosporin A (ISO)
	cytochalasin D (ISO)
	D-glucosamine (ISO)
	D-glucose (ISO)
	dacarbazine (ISO)
	daidzein (ISO)
	danazol (ISO)
	dapsone (ISO)
	daunorubicin (ISO)
	DDE (ISO)
	DDT (ISO)
	decane (ISO)
	Deguelin (ISO)
	dehydroepiandrosterone (ISO)
	deoxynivalenol (ISO)
	dequalinium (ISO)
	desferrioxamine B (ISO)
	desloratadine (ISO)
	dexamethasone (EXP,ISO)
	dextran sulfate (EXP)
	diazepam (ISO)
	diazinon (ISO)
	dibenziodolium (ISO)
	dibutyl phthalate (ISO)
	dichloromethane (ISO)
	dichromium trioxide (ISO)
	diclofenac (ISO)
	dicoumarol (ISO)
	dienogest (ISO)
	diethanolamine (ISO)
	diethyl maleate (ISO)
	diethyl phthalate (ISO)
	digitoxigenin (ISO)
	digitoxin (ISO)
	digoxigenin (ISO)
	digoxin (ISO)
	dimethoate (ISO)
	dimethyl sulfoxide (ISO)
	dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium (ISO)
	dimethylarsinous acid (ISO)
	dinitrogen (ISO)
	dioxygen (ISO)
	diphenhydramine (ISO)
	diphenylmethane-4,4'-diisocyanate (ISO)
	divanadium pentaoxide (ISO)
	dobutamine (ISO)
	dodecan-1-ol (ISO)
	dodecane (ISO)
	dodecanoic acid (ISO)
	doramapimod (ISO)
	doxorubicin (ISO)
	doxycycline (ISO)
	ebselen (ISO)
	efavirenz (ISO)
	elemental selenium (ISO)
	elesclomol (ISO)
	ellagic acid (ISO)
	embelin (ISO)
	emetine (ISO)
	enalapril (ISO)
	endosulfan (ISO)
	enniatin (EXP)
	entinostat (EXP)
	eriodictyol (ISO)
	erlotinib hydrochloride (ISO)
	erythromycin A (ISO)
	ethanol (EXP,ISO)
	ethylbenzene (ISO)
	ethylene glycol bis(2-aminoethyl)tetraacetic acid (ISO)
	ethylenediamine (ISO)
	ethylenediaminetetraacetic acid (ISO)
	ethylisopropylamiloride (ISO)
	etoposide (ISO)
	eugenol (ISO)
	farnesol (ISO)
	fenbendazole (ISO)
	fenoterol (ISO)
	ferric oxide (ISO)
	ferrosoferric oxide (ISO)
	ferrous oxide (ISO)
	fisetin (ISO)
	Flunitrazepam (ISO)
	fluoranthene (ISO)
	flutamide (ISO)
	fluticasone (ISO)
	folic acid (ISO)
	formaldehyde (EXP,ISO)
	formononetin (ISO)
	formoterol fumarate (ISO)
	fragrance (ISO)
	fulvestrant (EXP,ISO)
	fumonisin B1 (ISO)
	galactose (ISO)
	galangin (ISO)
	gallic acid (ISO)
	gastrin-17 (ISO)
	gefitinib (ISO)
	geldanamycin (ISO)
	gemcitabine (ISO)
	genistein (EXP,ISO)
	geranial (ISO)
	geraniol (ISO)
	ginsenoside C-K (ISO)
	ginsenoside F1 (ISO)
	gliotoxin (ISO)
	glucose (ISO)
	glutaraldehyde (ISO)
	glutathione (ISO)
	glutathione disulfide (ISO)
	glycerol (ISO)
	glycyrrhetinate (EXP)
	glycyrrhetinic acid (EXP)
	glycyrrhizinic acid (EXP,ISO)
	glyoxal (ISO)
	graphite (ISO)
	GW 3965 (ISO)
	harmaline (ISO)
	helenalin (ISO)
	heparin (ISO)
	hesperidin (ISO)
	hexadecane (ISO)
	hexadecanoic acid (ISO)
	hexanal (ISO)
	hexane (ISO)
	histamine (ISO)
	homocysteine (ISO)
	hyaluronic acid (ISO)
	hydrogen chloride (ISO)
	hydrogen peroxide (ISO)
	hydroquinone (ISO)
	hydroxychloroquine (ISO)
	hydroxycitronellal (ISO)
	hyperforin (ISO)
	ibufenac (ISO)
	ICI 118551 (ISO)
	imidurea (ISO)
	indometacin (ISO)
	iohexol (ISO)
	ionomycin (ISO)
	iopamidol (ISO)
	irinotecan (ISO)
	iron atom (EXP,ISO)
	iron trichloride (ISO)
	iron(0) (EXP,ISO)
	iron(2+) sulfate (anhydrous) (ISO)
	isocyanates (ISO)
	isoeugenol (ISO)
	isoflavones (ISO)
	isoniazide (ISO)
	isophorone diisocyanate (ISO)
	isoprenaline (ISO)
	itraconazole (ISO)
	ivermectin (ISO)
	kaempferol (ISO)
	ketanserin (ISO)
	ketoconazole (ISO)
	KN-93 (ISO)
	KT 5720 (ISO)
	L-ascorbic acid (ISO)
	L-cystathionine (ISO)
	L-cysteine (ISO)
	L-selenocysteine (ISO)
	lactacystin (ISO)
	lanatoside C (ISO)
	lansoprazole (ISO)
	lead diacetate (EXP,ISO)
	lead(0) (ISO)
	lead(2+) (ISO)
	lead(II) chloride (ISO)
	leflunomide (ISO)
	leptomycin B (ISO)
	leukotriene B4 (ISO)
	leukotriene D4 (ISO)
	leupeptin (ISO)
	lidocaine (ISO)
	limonene (ISO)
	lipid As (ISO)
	lipoarabinomannan (ISO)
	lipophosphoglycan (ISO)
	lipopolysaccharide (EXP,ISO)
	lipoteichoic acid (ISO)
	lipoxin A4 (ISO)
	lithium atom (ISO)
	lithium carbonate (ISO)
	lithium hydride (ISO)
	lithium(1+) (ISO)
	lithocholic acid (ISO)
	lucanthone (ISO)
	Luliconazole (ISO)
	luteolin (ISO)
	LY294002 (EXP,ISO)
	lycopene (ISO)
	m-xylene (ISO)
	magnesium sulfate (ISO)
	mancozeb (ISO)
	manganese atom (ISO)
	manganese(0) (ISO)
	manganese(2+) (ISO)
	manganese(II) chloride (ISO)
	mangiferin (EXP,ISO)
	mebendazole (ISO)
	meclocycline (ISO)
	melittin (ISO)
	menadione (ISO)
	mepyramine (ISO)
	mercury atom (ISO)
	mercury dichloride (ISO)
	mercury(0) (ISO)
	mercury(2+) (ISO)
	metformin (ISO)
	methimazole (ISO)
	methionine sulfoximine (ISO)
	methotrexate (ISO)
	methyl beta-cyclodextrin (ISO)
	methyl methacrylate (ISO)

	methyl non-2-ynoate (ISO)
	methyl salicylate (ISO)