Gh (growth hormone) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Gh (growth hormone) Mus musculus
Analyze
Symbol: Gh
Name: growth hormone
RGD ID: 10643
MGI Page MGI
Description: Exhibits growth hormone receptor binding activity. Involved in cellular response to insulin stimulus; regulation of growth; and response to food. Localizes to several cellular components, including extracellular space; secretory granule; and trans-Golgi network. Is expressed in blood; brain; early conceptus; and male reproductive system. Used to study isolated growth hormone deficiency type II. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune disease of endocrine system (multiple); diabetic retinopathy; isolated growth hormone deficiency (multiple); and progeria. Orthologous to several human genes including GH1 (growth hormone 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gh1; Ghb1; growth hormone b1; somatotropin
RGD Orthologs
Human
Rat
Bonobo
Squirrel
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911106,191,087 - 106,194,529 (-)NCBIGRCm39mm39
GRCm39 Ensembl11106,191,097 - 106,192,691 (-)Ensembl
GRCm3811106,300,261 - 106,303,703 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11106,300,271 - 106,301,865 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711106,161,582 - 106,163,124 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,116,358 - 106,117,900 (-)NCBImm8
Celera11118,030,755 - 118,032,297 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-trifluoroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxybutyric acid  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
4-tert-Octylphenol  (ISO)
7,12-dimethyltetraphene  (ISO)
9-cis-retinoic acid  (ISO)
afimoxifene  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apomorphine  (ISO)
arsenous acid  (ISO)
ATP  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzoates  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bromocriptine  (ISO)
butan-1-ol  (ISO)
butan-2-ol  (ISO)
butyric acid  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
CGP 12177  (ISO)
chlormequat chloride  (ISO)
chromium(6+)  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
corticotropin  (ISO)
cortisol  (ISO)
cypermethrin  (ISO)
cyproheptadine  (ISO)
D-glucose  (ISO)
dehydroepiandrosterone  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
disulfiram  (ISO)
dobutamine  (ISO)
doxorubicin  (ISO)
enalapril  (ISO)
endosulfan  (ISO)
estriol  (ISO)
ethanol  (ISO)
ethylbenzene  (ISO)
ethylene glycol  (ISO)
ethylenediaminetetraacetic acid  (ISO)
fenvalerate  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
glucose  (ISO)
Guanfacine  (ISO)
homocysteine  (ISO)
hydrogen sulfide  (EXP)
idazoxan  (ISO)
ionomycin  (ISO)
L-ascorbic acid  (ISO)
lead nitrate  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (EXP)
lisinopril dihydrate  (ISO)
maneb  (EXP)
mephenytoin  (ISO)
monosodium L-glutamate  (ISO)
morphine  (EXP,ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-methyl-N-nitrosourea  (ISO)
naproxen  (ISO)
nicotinic acid  (ISO)
Nivalenol  (ISO)
octreotide  (ISO)
p-tert-Amylphenol  (ISO)
paraquat  (EXP)
PCB138  (ISO)
pentetic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
phenylarsine oxide  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
progesterone  (ISO)
propan-1-ol  (ISO)
propan-2-ol  (ISO)
propane-1,2-diol  (ISO)
pyridoxal 5'-phosphate  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
SB 203580  (ISO)
sirtinol  (ISO)
sodium atom  (ISO)
sulpiride  (ISO)
sumatriptan  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP,ISO)
tert-butanol  (ISO)
testosterone  (ISO)
thimerosal  (EXP)
thioacetamide  (ISO)
thyroxine  (EXP,ISO)
titanium dioxide  (EXP)
triptonide  (EXP)
urethane  (EXP)
valproic acid  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Arcasoy A, etal., Pediatr Int. 1999 Dec;41(6):655-61.
2. Barreca T, etal., J Clin Endocrinol Metab. 1980 Dec;51(6):1279-82.
3. Birla S, etal., Growth Horm IGF Res. 2016 Aug;29:50-6. doi: 10.1016/j.ghir.2016.04.001. Epub 2016 Apr 16.
4. Bouillon R Verh K Acad Geneeskd Belg. 1992;54(4):365-91; discussion 391-2.
5. Castagnino HE, etal., Neuro Endocrinol Lett. 2002 Oct-Dec;23(5-6):391-5.
6. Cocco C, etal., Autoimmunity. 2012 Sep;45(6):485-94. doi: 10.3109/08916934.2012.680632. Epub 2012 May 18.
7. de Almeida Leme JA, etal., Pituitary. 2009;12(4):304-8. Epub 2009 Apr 16.
8. Dequeker J, etal., Horm Res. 1982;16(6):353-6.
9. Ekenstedt KJ, etal., Arthritis Rheum. 2006 Dec;54(12):3850-8.
10. Flavell DM, etal., EMBO J. 1996 Aug 1;15(15):3871-9.
11. Guo X, etal., Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2001 Dec;15(4):339-41.
12. Hao Y, etal., Chin J Traumatol. 2001 May;4(2):102-5.
13. Horner JM, etal., J Clin Endocrinol Metab. 1981 Dec;53(6):1148-53.
14. Howell JC, etal., Pediatr Blood Cancer. 2015 Mar;62(3):402-8. doi: 10.1002/pbc.25341. Epub 2014 Dec 9.
15. Leheup BP, etal., J Endocrinol Invest. 1991 Jan;14(1):37-40.
16. Li W, etal., Zhonghua Yi Xue Za Zhi. 1998 Jun;78(6):413-5.
17. Locatelli V, etal., Brain Res. 1985 Aug 19;341(1):35-40.
18. Lopez-Espinoza I, etal., Diabetes Res. 1986 Mar;3(3):119-25.
19. Madeira JL, etal., Eur J Endocrinol. 2016 Aug;175(2):K7-K15. doi: 10.1530/EJE-15-0149. Epub 2016 Jun 1.
20. Marino G, etal., Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16268-73. doi: 10.1073/pnas.1002696107. Epub 2010 Aug 30.
21. MGD and Homologene mouse data transfer
22. MGD data from the GO Consortium
23. MGD IEA
24. Moell C, etal., Arch Dis Child. 1989 Feb;64(2):252-8.
25. Molina G, etal., J Pediatr Endocrinol Metab. 2003 Oct-Nov;16(8):1143-55.
26. Navalesi R, etal., Diabetes. 1975 Apr;24(4):317-27.
27. Nogami H, etal., Endocrinology. 1989 Aug;125(2):964-70.
28. Okazaki K, etal., Endocrinology. 1999 Oct;140(10):4821-30.
29. OMIM Disease Annotation Pipeline
30. Online Mendelian Inheritance in Man, OMIM (TM).
31. Pipeline to import KEGG annotations from KEGG into RGD
32. Pontiroli AE, etal., J Endocrinol Invest. 1988 May;11(5):389-91.
33. RGD automated import pipeline
34. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
35. RGD automated import pipeline for gene-chemical interactions
36. Rose DP, etal., Anticancer Res. 1983 Sep-Oct;3(5):323-5.
37. Saceda J, etal., Neurosci Lett. 2011 Oct 24;504(2):146-50. doi: 10.1016/j.neulet.2011.09.020. Epub 2011 Sep 17.
38. Santos DP, etal., Growth Horm IGF Res. 2010 Apr;20(2):149-55. doi: 10.1016/j.ghir.2009.11.007. Epub 2010 Jan 8.
39. Serri O and Brazeau P, Neuroendocrinology. 1987 Aug;46(2):162-6.
40. Shen Q, etal., Endocrinology. 2007 Oct;148(10):4536-44. Epub 2007 Jun 21.
41. Sohmiya M and Kato Y, Clin Endocrinol (Oxf). 2001 Dec;55(6):749-54.
42. Song CJ, etal., Int J Clin Exp Med. 2015 Jul 15;8(7):10411-9. eCollection 2015.
43. Takahashi Y, etal., J Clin Invest. 1997 Sep 1;100(5):1159-65.
44. Takeuchi T, etal., Endocrinology. 1990 Jan;126(1):31-8.
45. Tang H, etal., J Neurosci Res. 2011 Feb;89(2):248-55. doi: 10.1002/jnr.22540. Epub 2010 Dec 8.
46. Vanelli M, etal., J Endocrinol Invest. 1986 Aug;9(4):293-7.
47. Wassenaar MJ, etal., J Clin Endocrinol Metab. 2009 Dec;94(12):4671-8. doi: 10.1210/jc.2009-1172. Epub 2009 Oct 28.
48. Wei L, etal., Biochem Cell Biol. 2010 Aug;88(4):723-30. doi: 10.1139/O10-022.
49. Wolf N, etal., Exp Eye Res. 2005 Sep;81(3):276-85.
50. Yigiter M, etal., Eur J Obstet Gynecol Reprod Biol. 2011 Jul;157(1):94-100. doi: 10.1016/j.ejogrb.2011.02.012. Epub 2011 Mar 25.
51. Ziaei M, etal., Neurosci Lett. 2009 Aug 21;460(1):87-91. Epub 2009 May 20.
Additional References at PubMed
PMID:1311971   PMID:1329576   PMID:1334535   PMID:1358809   PMID:1525063   PMID:1628813   PMID:1643309   PMID:1679528   PMID:1874564   PMID:1889803   PMID:1889815   PMID:2165966  
PMID:2249485   PMID:2286379   PMID:2836164   PMID:2963825   PMID:2991252   PMID:3780533   PMID:6262212   PMID:7613042   PMID:7664670   PMID:7733275   PMID:7740179   PMID:7760844  
PMID:7782295   PMID:7956352   PMID:7965203   PMID:8027530   PMID:8391647   PMID:8397485   PMID:8449498   PMID:8496314   PMID:8552145   PMID:8595891   PMID:8612966   PMID:8638120  
PMID:8647448   PMID:8661048   PMID:8742817   PMID:8756530   PMID:8833235   PMID:8875899   PMID:8887166   PMID:8923471   PMID:8934515   PMID:8981482   PMID:8990189   PMID:9118797  
PMID:9144201   PMID:9175714   PMID:9177778   PMID:9247269   PMID:9275086   PMID:9333128   PMID:9388186   PMID:9546108   PMID:9556071   PMID:9620855   PMID:9624169   PMID:10049363  
PMID:10076541   PMID:10349636   PMID:10367888   PMID:10395045   PMID:10451227   PMID:10459853   PMID:10465256   PMID:10467223   PMID:10478489   PMID:10556764   PMID:10556780   PMID:10559399  
PMID:10564535   PMID:10588713   PMID:10594738   PMID:10628753   PMID:10689811   PMID:10767558   PMID:10810296   PMID:10882104   PMID:10974531   PMID:10984300   PMID:11042159   PMID:11076861  
PMID:11087842   PMID:11152636   PMID:11195349   PMID:11217851   PMID:11309401   PMID:11316754   PMID:11318985   PMID:11346667   PMID:11350075   PMID:11487592   PMID:11570960   PMID:11731482  
PMID:11807026   PMID:12010633   PMID:12153463   PMID:12163409   PMID:12166626   PMID:12175649   PMID:12183375   PMID:12208853   PMID:12225773   PMID:12368809   PMID:12399427   PMID:12464179  
PMID:12466851   PMID:12477932   PMID:12563029   PMID:12586770   PMID:12651892   PMID:12759574   PMID:12907761   PMID:12933669   PMID:14530511   PMID:14563698   PMID:14583653   PMID:14596666  
PMID:14702113   PMID:14726438   PMID:14726450   PMID:14759511   PMID:14981518   PMID:14984790   PMID:15037319   PMID:15044591   PMID:15070902   PMID:15090034   PMID:15138153   PMID:15166120  
PMID:15231871   PMID:15242989   PMID:15314086   PMID:15314164   PMID:15316240   PMID:15363417   PMID:15456744   PMID:15459176   PMID:15489334   PMID:15606491   PMID:15616010   PMID:15661635  
PMID:15664625   PMID:15734145   PMID:15761027   PMID:15899943   PMID:15985453   PMID:16141072   PMID:16141073   PMID:16141355   PMID:16141391   PMID:16201410   PMID:16384867   PMID:16456855  
PMID:16467156   PMID:16508206   PMID:16513828   PMID:16556738   PMID:16602821   PMID:16678101   PMID:16840533   PMID:16840539   PMID:16932809   PMID:17015435   PMID:17234973   PMID:17242167  
PMID:17272395   PMID:17272398   PMID:17284572   PMID:17301034   PMID:17347312   PMID:17359964   PMID:17367776   PMID:17392792   PMID:17396120   PMID:17426285   PMID:17626886   PMID:17698843  
PMID:17717072   PMID:17761891   PMID:17881271   PMID:17975745   PMID:18006625   PMID:18040896   PMID:18180319   PMID:18203262   PMID:18272476   PMID:18287078   PMID:18287559   PMID:18351662  
PMID:18462884   PMID:18535104   PMID:18585098   PMID:18617616   PMID:18618017   PMID:18716208   PMID:18757483   PMID:18775421   PMID:18831980   PMID:18948397   PMID:18996108   PMID:19010462  
PMID:19019400   PMID:19093031   PMID:19122000   PMID:19139274   PMID:19301152   PMID:19359380   PMID:19366684   PMID:19398579   PMID:19417088   PMID:19433492   PMID:19460757   PMID:19619004  
PMID:19797429   PMID:19900438   PMID:20032199   PMID:20162728   PMID:20231469   PMID:20593419   PMID:20682777   PMID:20707609   PMID:20807761   PMID:20863500   PMID:20934421   PMID:21045135  
PMID:21084383   PMID:21084450   PMID:21098290   PMID:21247964   PMID:21262217   PMID:21267068   PMID:21636786   PMID:21725989   PMID:21741628   PMID:21832120   PMID:21849508   PMID:21852148  
PMID:21873635   PMID:21971153   PMID:21990313   PMID:22031092   PMID:22421044   PMID:22467218   PMID:22791713   PMID:22844247   PMID:22890843   PMID:22945632   PMID:23010755   PMID:23059197  
PMID:23070814   PMID:23143598   PMID:23150490   PMID:23150495   PMID:23209615   PMID:23284914   PMID:23288907   PMID:23349524   PMID:23428905   PMID:23595986   PMID:23639351   PMID:23674600  
PMID:23689346   PMID:23708999   PMID:23782652   PMID:23861378   PMID:23913444   PMID:23980167   PMID:24109593   PMID:24190208   PMID:24194600   PMID:24218587   PMID:24227653   PMID:24284820  
PMID:24517230   PMID:24673559   PMID:24691732   PMID:24758742   PMID:24759003   PMID:24949662   PMID:25017732   PMID:25085903   PMID:25105693   PMID:25119036   PMID:25179284   PMID:25315894  
PMID:25519132   PMID:25551181   PMID:25605944   PMID:25645493   PMID:25691498   PMID:25811804   PMID:25907274   PMID:25936582   PMID:26015548   PMID:26075743   PMID:26134413   PMID:26292757  
PMID:26296153   PMID:26442444   PMID:26465715   PMID:26651607   PMID:26697363   PMID:26762506   PMID:26764381   PMID:26812162   PMID:26862561   PMID:26887678   PMID:26997624   PMID:27079169  
PMID:27184910   PMID:27226307   PMID:27226320   PMID:27558671   PMID:27616671   PMID:27626380   PMID:27631552   PMID:27771355   PMID:27776119   PMID:27810956   PMID:27825319   PMID:28506993  
PMID:28807898   PMID:28911172   PMID:28938441   PMID:29180744   PMID:29263200   PMID:29578405   PMID:29796621   PMID:30085028   PMID:30307165   PMID:30333823   PMID:30400015   PMID:30811539  
PMID:30910968   PMID:30982661   PMID:31099824   PMID:31436800   PMID:31479305   PMID:31781038   PMID:31913463   PMID:32100023   PMID:32423821   PMID:32556100   PMID:32644973   PMID:33112796  
PMID:33248443  


Genomics

Comparative Map Data
Gh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911106,191,087 - 106,194,529 (-)NCBIGRCm39mm39
GRCm39 Ensembl11106,191,097 - 106,192,691 (-)Ensembl
GRCm3811106,300,261 - 106,303,703 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11106,300,271 - 106,301,865 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711106,161,582 - 106,163,124 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,116,358 - 106,117,900 (-)NCBImm8
Celera11118,030,755 - 118,032,297 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.89NCBI
GH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1763,917,200 - 63,918,839 (-)EnsemblGRCh38hg38GRCh38
GRCh381763,917,203 - 63,918,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371761,994,563 - 61,996,199 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,348,295 - 59,349,930 (-)NCBINCBI36hg18NCBI36
Build 341759,348,294 - 59,349,930NCBI
Celera1756,382,602 - 56,384,237 (-)NCBI
Cytogenetic Map17q23.3NCBI
HuRef1757,362,255 - 57,363,890 (-)NCBIHuRef
CHM1_11762,058,482 - 62,060,117 (-)NCBICHM1_1
Gh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21091,228,102 - 91,230,079 (-)NCBI
Rnor_6.0 Ensembl1094,486,205 - 94,488,180 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01094,486,204 - 94,488,181 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,237,414 - 94,239,391 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,692,240 - 95,694,117 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11095,708,476 - 95,710,261 (-)NCBI
Celera1089,903,834 - 89,905,811 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
LOC100971425
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11763,103,339 - 63,105,719 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01758,010,848 - 58,013,421 (-)NCBIMhudiblu_PPA_v0panPan3
LOC101969021
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560214,668,568 - 14,670,240 (+)NCBI
SpeTri2.0NW_0049365414,524,397 - 4,528,234 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0

Position Markers
BGH  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811106,300,550 - 106,300,812UniSTSGRCm38
MGSCv3711106,161,864 - 106,162,126UniSTSGRCm37
Celera11118,031,037 - 118,031,299UniSTS
Cytogenetic Map11DUniSTS
cM Map1165.0UniSTS
Gh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811106,300,366 - 106,301,775UniSTSGRCm38
MGSCv3711106,161,680 - 106,163,089UniSTSGRCm37
Celera11118,030,853 - 118,032,262UniSTS
Cytogenetic Map11DUniSTS
cM Map1165.0UniSTS
cM Map1165.0UniSTS
cM Map1165.0UniSTS
GHI  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811106,300,830 - 106,301,522UniSTSGRCm38
MGSCv3711106,162,144 - 106,162,836UniSTSGRCm37
Celera11118,031,317 - 118,032,009UniSTS
Cytogenetic Map11DUniSTS
cM Map1165.0UniSTS
Gh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811106,300,423 - 106,300,503UniSTSGRCm38
MGSCv3711106,161,737 - 106,161,817UniSTSGRCm37
Celera11118,030,910 - 118,030,990UniSTS
Cytogenetic Map11DUniSTS
cM Map1165.0UniSTS
Gh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811106,300,355 - 106,300,484UniSTSGRCm38
MGSCv3711106,161,669 - 106,161,798UniSTSGRCm37
Celera11118,030,842 - 118,030,971UniSTS
Cytogenetic Map11DUniSTS
cM Map1165.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185954085119954085Mouse
15039374Adip29_madiposity 29 (mouse)1186717494120717494Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186717494120717494Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186717494120717494Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1193048547112653728Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194172953118131898Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194300000119000000Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94546357118131898Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195513139122082543Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195513139122082543Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196246848122082543Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196285639108915558Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196919310122082543Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1197006867110713165Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198461783122082543Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198609643122082543Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199363361122082543Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100167277122082543Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100363360120996339Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101131764122082543Mouse
14700693Ppiq12_mprepulse inhibition QTL 12 (mouse)11101613994114581537Mouse
14700694Ppiq13_mprepulse inhibition QTL 13 (mouse)11101613994114581537Mouse
14700695Ppiq14_mprepulse inhibition QTL 14 (mouse)11101613994114581537Mouse
14700696Ppiq15_mprepulse inhibition QTL 15 (mouse)11101613994114581537Mouse
1300957Pbd1_mpeak bone density 1 (mouse)Not determined11102453297112493297Mouse
4141612Cia40_mcollagen induced arthritis 40 (mouse)Not determined11103383166115130618Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:213
Count of miRNA genes:206
Interacting mature miRNAs:211
Transcripts:ENSMUST00000103071
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK019952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL604045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB024006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC061157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LM644167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U34362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z46663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000103071   ⟹   ENSMUSP00000099360
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11106,300,271 - 106,301,865 (-)Ensembl
RefSeq Acc Id: NM_008117   ⟹   NP_032143
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911106,191,087 - 106,192,722 (-)NCBI
GRCm3811106,300,261 - 106,301,896 (-)NCBI
MGSCv3711106,161,582 - 106,163,124 (-)RGD
Celera11118,030,748 - 118,032,383 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532223   ⟹   XP_006532286
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911106,191,094 - 106,194,529 (-)NCBI
GRCm3811106,300,268 - 106,303,703 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032143   ⟸   NM_008117
- Peptide Label: precursor
- UniProtKB: P06880 (UniProtKB/Swiss-Prot),   A0A0M6L0K7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006532286   ⟸   XM_006532223
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000099360   ⟸   ENSMUST00000103071

Promoters
RGD ID:8677080
Promoter ID:EPDNEW_M16571
Type:multiple initiation site
Name:Gh_1
Description:Mus musculus growth hormone , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811106,301,810 - 106,301,870EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95707 AgrOrtholog
Ensembl Genes ENSMUSG00000020713 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000099360 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000103071 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Somatotropin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Somatotropin/Prolactin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Somatotropin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14599 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95707 ENTREZGENE
NCBI Gene 14599 ENTREZGENE
PANTHER PTHR11417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11417:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gh PhenoGen
PRINTS SOMATOTROPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SOMATOTROPIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOMATOTROPIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0M6L0K7 ENTREZGENE, UniProtKB/TrEMBL
  P06880 ENTREZGENE
  Q8BK24_MOUSE UniProtKB/TrEMBL
  SOMA_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q544X1 UniProtKB/Swiss-Prot