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Gene: Gh (growth hormone) Mus musculus
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Symbol: Gh
Name: growth hormone
Description: Exhibits growth hormone receptor binding activity. Involved in cellular response to insulin stimulus; positive regulation of growth; and response to food. Localizes to several cellular components, including the extracellular space; secretory granule; and trans-Golgi network. Used to study isolated growth hormone deficiency type II. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune polyendocrine syndrome type 1; beta thalassemia; isolated growth hormone deficiency (multiple); and progeria. Is expressed in blood; brain; and male reproductive system. Orthologous to several human genes including GH1 (growth hormone 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gh1; Ghb1; growth hormone b1; somatotropin
Orthologs:
Homo sapiens (human) : GH1 (growth hormone 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gh1 (growth hormone 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100971425 (somatotropin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969021 (somatotropin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl11106,300,271 - 106,301,865 (-)Ensembl
GRCm3811106,300,261 - 106,303,703 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711106,161,582 - 106,163,124 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,116,358 - 106,117,900 (-)NCBImm8
Celera11118,030,748 - 118,032,383 (-)NCBICelera
Cytogenetic Map11 E1NCBI
cM Map1168.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10643
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.