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Gene: Gh (growth hormone) Mus musculus
Symbol: Gh
Name: growth hormone
Description: Exhibits growth hormone receptor binding activity. Involved in cellular response to insulin stimulus; positive regulation of growth; and response to food. Localizes to several cellular components, including the extracellular space; secretory granule; and trans-Golgi network. Used to study isolated growth hormone deficiency type II. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune polyendocrine syndrome type 1; beta thalassemia; isolated growth hormone deficiency (multiple); and progeria. Is expressed in blood; brain; and male reproductive system. Orthologous to several human genes including GH1 (growth hormone 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gh1; Ghb1; growth hormone b1; somatotropin
Homo sapiens (human) : GH1 (growth hormone 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gh1 (growth hormone 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100971425 (somatotropin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969021 (somatotropin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl11106,300,271 - 106,301,865 (-)Ensembl
GRCm3811106,300,261 - 106,303,703 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711106,161,582 - 106,163,124 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,116,358 - 106,117,900 (-)NCBImm8
Celera11118,030,748 - 118,032,383 (-)NCBICelera
Cytogenetic Map11 E1NCBI
cM Map1168.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gh
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10643
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.