Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10643
Species: Mus musculus
RGD Object: Gene
Symbol: Gh
Name: growth hormone
Acc ID: CHEBI:31429
Term: colforsin daropate hydrochloride
Definition: The hydrochloride salt of colforsin daropate. It is a drug used for the treatment of acute heart failure. It directly stimulates adenylate cyclase and produces positive inotropic and vasodilator effects accompanied by the increase in cellular cAMP.
Chemical ID: MESH:D005576
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ghincreases secretionISOGH1 (Homo sapiens)6480464CTDColforsin results in increased secretion of GH1 proteinPMID:19952226
Ghmultiple interactionsISOGh1 (Rattus norvegicus)6480464CTDGH1 protein promotes the reaction [Colforsin results in increased metabolism of Lipids]PMID:14981226
Go Back to source page   Continue to Ontology report