Fam110c (family with sequence similarity 110, member C) - Rat Genome Database

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Gene: Fam110c (family with sequence similarity 110, member C) Mus musculus
Analyze
Symbol: Fam110c
Name: family with sequence similarity 110, member C
RGD ID: 1616655
MGI Page MGI
Description: Predicted to enable alpha-tubulin binding activity. Predicted to be involved in positive regulation of cell migration; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of cell projection assembly. Predicted to be located in cytoplasm; microtubule; and nucleus. Predicted to be active in cell cortex. Is expressed in adrenal gland and pancreas epithelium. Orthologous to human FAM110C (family with sequence similarity 110 member C).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 9030611O19Rik; AU019489
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391231,123,967 - 31,129,939 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1231,123,860 - 31,130,250 (+)EnsemblGRCm39 Ensembl
GRCm381231,073,968 - 31,079,940 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1231,073,861 - 31,080,251 (+)EnsemblGRCm38mm10GRCm38
MGSCv371231,758,833 - 31,764,805 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361231,660,023 - 31,665,995 (+)NCBIMGSCv36mm8
Celera1232,522,905 - 32,528,736 (+)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell cortex  (IBA,ISO)
cytoplasm  (IEA)
cytoskeleton  (IEA)
microtubule  (IEA)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:18554416   PMID:21267068  
PMID:21873635  


Genomics

Comparative Map Data
Fam110c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391231,123,967 - 31,129,939 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1231,123,860 - 31,130,250 (+)EnsemblGRCm39 Ensembl
GRCm381231,073,968 - 31,079,940 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1231,073,861 - 31,080,251 (+)EnsemblGRCm38mm10GRCm38
MGSCv371231,758,833 - 31,764,805 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361231,660,023 - 31,665,995 (+)NCBIMGSCv36mm8
Celera1232,522,905 - 32,528,736 (+)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.06NCBI
FAM110C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38238,814 - 46,505 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl238,814 - 46,870 (-)EnsemblGRCh38hg38GRCh38
GRCh37238,814 - 46,505 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36231,608 - 36,385 (-)NCBINCBI36Build 36hg18NCBI36
Celera295,571 - 103,345 (-)NCBICelera
Cytogenetic Map2p25.3NCBI
HuRef229,297 - 37,071 (-)NCBIHuRef
CHM1_1238,316 - 46,090 (-)NCBICHM1_1
T2T-CHM13v2.0232,180 - 40,449 (-)NCBIT2T-CHM13v2.0
Fam110c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8653,366,013 - 53,372,270 (+)NCBIGRCr8
mRatBN7.2647,638,466 - 47,644,723 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl647,638,276 - 47,644,634 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx647,944,208 - 47,950,218 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0648,259,130 - 48,265,140 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0647,702,016 - 47,708,032 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0649,968,473 - 49,974,730 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl649,968,473 - 49,974,728 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0658,647,800 - 58,654,057 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4648,916,302 - 48,922,559 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera646,843,225 - 46,849,154 (+)NCBICelera
Cytogenetic Map6q16NCBI
Fam110c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955487207,945 - 213,899 (-)NCBIChiLan1.0ChiLan1.0
FAM110C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212126,505,353 - 126,513,333 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A126,509,329 - 126,517,309 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A27,359 - 35,345 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A29,607 - 37,389 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A29,607 - 37,389 (-)Ensemblpanpan1.1panPan2
FAM110C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11783,132 - 90,893 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1789,772 - 90,893 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1774,516 - 82,277 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.017140,755 - 148,528 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11769,588 - 77,361 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01787,461 - 95,239 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01792,299 - 100,072 (-)NCBIUU_Cfam_GSD_1.0
Fam110c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629245,269,130 - 45,276,055 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493653224,178 - 30,543 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493653224,176 - 30,715 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM110C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3132,811,629 - 132,816,901 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13132,810,038 - 132,819,554 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FAM110C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114107,661,612 - 107,667,351 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660454,280,629 - 4,288,808 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam110c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248461,661,653 - 1,669,535 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fam110c
203 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:354
Count of miRNA genes:265
Interacting mature miRNAs:301
Transcripts:ENSMUST00000041133
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121062064244620809Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132758756Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133430339Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12805000040049999Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
1300870Ath18_matherosclerosis 18 (mouse)Not determined121825996652260067Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1234013434340302Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
4141516slwr_mslowlearner (mouse)Not determined1239247546392614Mouse
10043977Obq34_mobesity QTL 34 (mouse)Not determined121514733149147331Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12772315841723301Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
26884413Bzwq9_mbi-zygomatic width QTL 9, 10 week (mouse)121615000147746783Mouse
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12949100443491112Mouse
15039339Nmrs29_mNAFLD-associated magnetic resonance shift 29 (mouse)121782585251825852Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12835244442352581Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
14746972Manh72_mmandible shape 72 (mouse)121061528144615281Mouse
10043848Hdlq90_mHDL QTL 90 (mouse)Not determined121783993951840081Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse

Markers in Region
RH136403  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381231,079,516 - 31,079,709UniSTSGRCm38
MGSCv371231,764,381 - 31,764,574UniSTSGRCm37
Celera1232,528,312 - 32,528,505UniSTS
Cytogenetic Map12A2UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000041133   ⟹   ENSMUSP00000041563
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1231,123,860 - 31,130,250 (+)Ensembl
GRCm38.p6 Ensembl1231,073,861 - 31,080,251 (+)Ensembl
RefSeq Acc Id: NM_027828   ⟹   NP_082104
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391231,123,967 - 31,129,939 (+)NCBI
GRCm381231,073,968 - 31,079,940 (+)ENTREZGENE
MGSCv371231,758,833 - 31,764,805 (+)RGD
Celera1232,522,905 - 32,528,736 (+)RGD
cM Map12 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_082104 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH19466 (Get FASTA)   NCBI Sequence Viewer  
  AAH85288 (Get FASTA)   NCBI Sequence Viewer  
  BAB31266 (Get FASTA)   NCBI Sequence Viewer  
  BAE35611 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000041563
  ENSMUSP00000041563.9
GenBank Protein Q8VE94 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_082104   ⟸   NM_027828
- UniProtKB: Q9D322 (UniProtKB/Swiss-Prot),   Q8VE94 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000041563   ⟸   ENSMUST00000041133

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VE94-F1-model_v2 AlphaFold Q8VE94 1-421 view protein structure

Promoters
RGD ID:8678080
Promoter ID:EPDNEW_M17071
Type:initiation region
Name:Fam110c_1
Description:Mus musculus family with sequence similarity 110, member C ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381231,073,997 - 31,074,057EPDNEW
RGD ID:6822938
Promoter ID:MM_KWN:11426
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Kidney,   Lung
Transcripts:ENSMUST00000041133
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361231,758,531 - 31,760,112 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918813 AgrOrtholog
Ensembl Genes ENSMUSG00000036136 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000041133 ENTREZGENE
  ENSMUST00000041133.10 UniProtKB/Swiss-Prot
InterPro FAM110 UniProtKB/Swiss-Prot
  FAM110_C UniProtKB/Swiss-Prot
KEGG Report mmu:104943 UniProtKB/Swiss-Prot
MGD MGI:1918813 ENTREZGENE
NCBI Gene 104943 ENTREZGENE
PANTHER PROTEIN FAM110C UniProtKB/Swiss-Prot
  PTHR14758 UniProtKB/Swiss-Prot
Pfam FAM110_C UniProtKB/Swiss-Prot
PhenoGen Fam110c PhenoGen
UniProt F110C_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9D322 ENTREZGENE
UniProt Secondary Q9D322 UniProtKB/Swiss-Prot