Ms4a14 (membrane-spanning 4-domains, subfamily A, member 14) - Rat Genome Database

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Gene: Ms4a14 (membrane-spanning 4-domains, subfamily A, member 14) Mus musculus
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Symbol: Ms4a14
Name: membrane-spanning 4-domains, subfamily A, member 14
RGD ID: 1614011
MGI Page MGI
Description: Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human MS4A14 (membrane spanning 4-domains A14).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm1276; membrane-spanning 4-domains subfamily A member 14; SP3111
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391911,278,613 - 11,293,239 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1911,278,613 - 11,291,818 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381911,301,249 - 11,315,877 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1911,301,249 - 11,314,454 (-)Ensemblmm10GRCm38
MGSCv371911,375,984 - 11,388,823 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361911,368,294 - 11,381,378 (-)NCBIMGSCv36mm8
Celera1911,979,485 - 11,992,319 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map198.37NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18689890   PMID:20180398   PMID:20562862   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Ms4a14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391911,278,613 - 11,293,239 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1911,278,613 - 11,291,818 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381911,301,249 - 11,315,877 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1911,301,249 - 11,314,454 (-)Ensemblmm10GRCm38
MGSCv371911,375,984 - 11,388,823 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361911,368,294 - 11,381,378 (-)NCBIMGSCv36mm8
Celera1911,979,485 - 11,992,319 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map198.37NCBI
MS4A14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,396,459 - 60,417,756 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,378,530 - 60,417,756 (+)Ensemblhg38GRCh38
GRCh371160,163,932 - 60,185,229 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,920,063 - 59,941,805 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1157,527,870 - 57,549,614 (+)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1156,510,292 - 56,532,001 (+)NCBIHuRef
CHM1_11160,029,518 - 60,051,230 (+)NCBICHM1_1
T2T-CHM13v2.01160,347,724 - 60,368,988 (+)NCBIT2T-CHM13v2.0
Ms4a14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81217,374,325 - 217,389,839 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1217,374,328 - 217,389,839 (-)EnsemblGRCr8
mRatBN7.21207,949,423 - 207,964,937 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,949,426 - 207,964,937 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1216,324,274 - 216,339,786 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,388,380 - 223,403,878 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01216,078,686 - 216,094,202 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01227,471,441 - 227,486,953 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1227,471,436 - 227,486,976 (-)Ensemblrn6Rnor6.0
Rnor_5.01234,536,324 - 234,551,836 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41213,809,166 - 213,824,678 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1205,424,565 - 205,440,077 (-)NCBICelera
RGSC_v3.11213,967,598 - 213,983,108 (-)NCBI
Cytogenetic Map1q43NCBI
Ms4a14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555115,211,917 - 5,229,938 (+)Ensembl
ChiLan1.0NW_0049555115,211,454 - 5,229,099 (+)NCBIChiLan1.0ChiLan1.0
MS4A14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2961,538,170 - 61,559,404 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11162,582,338 - 62,603,568 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01155,632,378 - 55,653,574 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,075,069 - 59,096,374 (+)NCBIPanPan1.1PanPan1.1panPan2
MS4A14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12150,663,060 - 50,690,248 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2150,103,739 - 50,130,886 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02151,836,401 - 51,863,584 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2151,836,396 - 51,863,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12150,882,922 - 50,910,060 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02150,981,393 - 51,008,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02151,605,440 - 51,632,630 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ms4a14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494712,388,976 - 12,408,489 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365812,503,640 - 2,522,184 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MS4A14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1211,269,456 - 11,291,611 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2210,828,356 - 10,849,768 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MS4A14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1113,384,442 - 13,408,540 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038110,726,528 - 110,750,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ms4a14
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1210,755,141 - 10,770,177 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ms4a14
387 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
38455997Cdtm2_mCD62L+ CD8 TM cells 2 (mouse)19997736419977364Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000187467   ⟹   ENSMUSP00000140996
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1911,278,613 - 11,291,818 (-)Ensembl
GRCm38.p6 Ensembl1911,301,249 - 11,314,454 (-)Ensembl
RefSeq Acc Id: NM_001377045   ⟹   NP_001363974
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391911,278,613 - 11,291,818 (-)NCBI
GRCm381911,301,249 - 11,314,454 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006527510   ⟹   XP_006527573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391911,278,613 - 11,291,853 (-)NCBI
GRCm381911,301,249 - 11,314,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006527511   ⟹   XP_006527574
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391911,278,613 - 11,291,854 (-)NCBI
GRCm381911,301,249 - 11,314,490 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247415   ⟹   XP_011245717
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391911,278,613 - 11,293,239 (-)NCBI
GRCm381911,301,249 - 11,315,877 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001363974 (Get FASTA)   NCBI Sequence Viewer  
  XP_006527573 (Get FASTA)   NCBI Sequence Viewer  
  XP_006527574 (Get FASTA)   NCBI Sequence Viewer  
  XP_011245717 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000140996
  ENSMUSP00000140996.2
RefSeq Acc Id: XP_006527573   ⟸   XM_006527510
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006527574   ⟸   XM_006527511
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011245717   ⟸   XM_011247415
- Peptide Label: isoform X1
- UniProtKB: A0A087WSD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001363974   ⟸   NM_001377045
- UniProtKB: A0A087WSD2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000140996   ⟸   ENSMUST00000187467

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A087WSD2-F1-model_v2 AlphaFold A0A087WSD2 1-1232 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2686122 AgrOrtholog
Ensembl Genes ENSMUSG00000099398 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000187467 ENTREZGENE
  ENSMUST00000187467.2 UniProtKB/TrEMBL
InterPro CD20-like UniProtKB/TrEMBL
  MS4A UniProtKB/TrEMBL
MGD MGI:2686122 ENTREZGENE
NCBI Gene 383435 ENTREZGENE
PANTHER MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 14 UniProtKB/TrEMBL
  PTHR23320 UniProtKB/TrEMBL
Pfam CD20 UniProtKB/TrEMBL
PhenoGen Ms4a14 PhenoGen
UniProt A0A087WSD2 ENTREZGENE, UniProtKB/TrEMBL