Fbxw9 (F-box and WD-40 domain protein 9) - Rat Genome Database

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Gene: Fbxw9 (F-box and WD-40 domain protein 9) Mus musculus
Analyze
Symbol: Fbxw9
Name: F-box and WD-40 domain protein 9
RGD ID: 1332534
MGI Page MGI
Description: Predicted to localize to preribosome, large subunit precursor. Is expressed in brain; endocrine gland; genitourinary system; spinal cord; and trigeminal nerve. Orthologous to human FBXW9 (F-box and WD repeat domain containing 9); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110017H11Rik; F-box/WD repeat-containing protein 9; Fbw9; MGC7678
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,786,748 - 85,793,750 (+)NCBIGRCm39mm39
GRCm39 Ensembl885,786,684 - 85,793,753 (+)Ensembl
GRCm38885,060,119 - 85,067,121 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,060,055 - 85,067,124 (+)EnsemblGRCm38mm10GRCm38
MGSCv37887,584,018 - 87,591,020 (+)NCBIGRCm37mm9NCBIm37
MGSCv36887,950,634 - 87,957,222 (+)NCBImm8
Celera889,354,869 - 89,361,739 (+)NCBICelera
Cytogenetic Map8C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15747579   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:24194600   PMID:27626380  


Genomics

Comparative Map Data
Fbxw9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,786,748 - 85,793,750 (+)NCBIGRCm39mm39
GRCm39 Ensembl885,786,684 - 85,793,753 (+)Ensembl
GRCm38885,060,119 - 85,067,121 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,060,055 - 85,067,124 (+)EnsemblGRCm38mm10GRCm38
MGSCv37887,584,018 - 87,591,020 (+)NCBIGRCm37mm9NCBIm37
MGSCv36887,950,634 - 87,957,222 (+)NCBImm8
Celera889,354,869 - 89,361,739 (+)NCBICelera
Cytogenetic Map8C3NCBI
FBXW9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1912,688,053 - 12,696,631 (-)EnsemblGRCh38hg38GRCh38
GRCh381912,688,916 - 12,696,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371912,799,730 - 12,807,445 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,660,730 - 12,668,455 (-)NCBINCBI36hg18NCBI36
Build 341912,660,730 - 12,668,432NCBI
Celera1912,689,444 - 12,697,169 (-)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,372,724 - 12,380,434 (-)NCBIHuRef
CHM1_11912,800,253 - 12,807,962 (-)NCBICHM1_1
Fbxw9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21923,090,534 - 23,097,439 (-)NCBI
Rnor_6.0 Ensembl1926,173,771 - 26,180,675 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01926,173,771 - 26,180,675 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01937,149,394 - 37,156,298 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,746,820 - 24,753,726 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11924,751,649 - 24,758,479 (-)NCBI
Celera1922,648,501 - 22,655,405 (-)NCBICelera
Cytogenetic Map19q11NCBI
Fbxw9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,787,002 - 31,794,174 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,788,115 - 31,794,174 (-)NCBIChiLan1.0ChiLan1.0
FBXW9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11912,996,061 - 13,003,564 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1912,996,061 - 13,003,564 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01912,250,790 - 12,259,199 (-)NCBIMhudiblu_PPA_v0panPan3
FBXW9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,425,423 - 49,430,673 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,425,534 - 49,430,667 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,299,037 - 49,304,250 (+)NCBI
ROS_Cfam_1.02049,943,914 - 49,949,125 (+)NCBI
UMICH_Zoey_3.12049,154,949 - 49,160,159 (+)NCBI
UNSW_CanFamBas_1.02049,581,463 - 49,586,674 (+)NCBI
UU_Cfam_GSD_1.02049,823,984 - 49,829,194 (+)NCBI
Fbxw9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,531,285 - 208,544,435 (+)NCBI
SpeTri2.0NW_0049366591,817,379 - 1,823,421 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXW9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl266,291,172 - 66,297,215 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1266,290,847 - 66,297,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,670,074 - 66,676,406 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXW9
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,376,476 - 11,384,600 (-)NCBI
ChlSab1.1 Ensembl611,374,898 - 11,384,361 (-)Ensembl
Fbxw9
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624901326,657 - 333,203 (-)NCBI

Position Markers
UniSTS:235947  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,062,114 - 85,062,314UniSTSGRCm38
MGSCv37887,586,013 - 87,586,213UniSTSGRCm37
Celera889,356,864 - 89,357,065UniSTS
Cytogenetic Map8C3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88006677589014359Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881092664115092664Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)881619151115619151Mouse
1301766Desp1_mdespair 1 (mouse)Not determined884759576118759741Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1447
Count of miRNA genes:488
Interacting mature miRNAs:578
Transcripts:ENSMUST00000095220, ENSMUST00000125109, ENSMUST00000139721, ENSMUST00000141183, ENSMUST00000142036, ENSMUST00000143763, ENSMUST00000145479, ENSMUST00000151962, ENSMUST00000152884
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC163703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB870341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP769909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF197934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000095220   ⟹   ENSMUSP00000092845
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,060,055 - 85,067,121 (+)Ensembl
RefSeq Acc Id: ENSMUST00000125109
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,064,595 - 85,066,325 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139721
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,060,056 - 85,067,124 (+)Ensembl
RefSeq Acc Id: ENSMUST00000141183
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,066,063 - 85,066,898 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142036
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,060,567 - 85,066,881 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143763
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,065,568 - 85,066,362 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145479
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,060,097 - 85,064,812 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151962
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,065,622 - 85,066,364 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152884
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,060,529 - 85,067,117 (+)Ensembl
RefSeq Acc Id: NM_026791   ⟹   NP_081067
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39885,786,748 - 85,793,750 (+)NCBI
GRCm38885,060,119 - 85,067,121 (+)NCBI
MGSCv37887,584,018 - 87,591,020 (+)RGD
Celera889,354,869 - 89,361,739 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_081067   ⟸   NM_026791
- UniProtKB: F8VPX2 (UniProtKB/TrEMBL),   Q6PAS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000092845   ⟸   ENSMUST00000095220
Protein Domains
F-box   WD_REPEATS_REGION

Promoters
RGD ID:8667737
Promoter ID:EPDNEW_M11900
Type:initiation region
Name:Fbxw9_1
Description:Mus musculus F-box and WD-40 domain protein 9 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38885,060,103 - 85,060,163EPDNEW
RGD ID:6843138
Promoter ID:MM_KWN:55131
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000077988,   OTTMUST00000077989,   OTTMUST00000077990,   OTTMUST00000077991,   UC009MPE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36887,583,096 - 87,585,237 (+)MPROMDB
RGD ID:6843139
Promoter ID:MM_KWN:55134
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:OTTMUST00000078022,   OTTMUST00000078023,   OTTMUST00000078024
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36887,589,271 - 87,589,872 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915878 AgrOrtholog
Ensembl Genes ENSMUSG00000008167 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000092845 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000095220 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro F-box_dom_cyclin-like UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report mmu:68628 UniProtKB/TrEMBL
MGD MGI:1915878 ENTREZGENE
NCBI Gene 68628 ENTREZGENE
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Fbxw9 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP F-box_dom_Skp2-like UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt F8VPX2 ENTREZGENE, UniProtKB/TrEMBL
  Q6PAS7 ENTREZGENE, UniProtKB/TrEMBL
  Q7TN10_MOUSE UniProtKB/TrEMBL
  Q80XN6_MOUSE UniProtKB/TrEMBL
  Q8C4I7_MOUSE UniProtKB/TrEMBL
  Q9D1B0_MOUSE UniProtKB/TrEMBL