Irf1 (interferon regulatory factor 1) - Rat Genome Database

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Gene: Irf1 (interferon regulatory factor 1) Mus musculus
Analyze
Symbol: Irf1
Name: interferon regulatory factor 1
RGD ID: 10815
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including defense response to symbiont; regulation of T cell activation; and regulation of gene expression. Acts upstream of or within CD8-positive, alpha-beta T cell differentiation; positive regulation of interleukin-12 production; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including bone marrow; early conceptus; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in asthma; gastric adenocarcinoma; lung non-small cell carcinoma; smallpox; and stomach cancer. Orthologous to human IRF1 (interferon regulatory factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AU020929; Irf; Irf-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,660,841 - 53,669,200 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,660,841 - 53,669,200 (+)EnsemblGRCm39 Ensembl
GRCm381153,770,014 - 53,778,374 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,770,014 - 53,778,374 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,583,516 - 53,591,876 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,613,501 - 53,620,746 (+)NCBIMGSCv36mm8
Celera1158,349,840 - 58,358,199 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1132.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-viniferin  (EXP)
(-)-demecolcine  (ISO)
(R)-lipoic acid  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1,4-benzoquinone  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-nitropyrene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-bromohexadecanoic acid  (ISO)
2-nitrofluorene  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-tert-Octylphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
9-cis-retinoic acid  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (EXP)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
beta-D-glucosamine  (EXP)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
buspirone  (ISO)
cadmium selenide  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloroprene  (ISO)
chlorpyrifos  (EXP)
chromium(6+)  (EXP)
ciglitazone  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
clofibric acid  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (ISO)
D-glucose  (EXP)
dacarbazine  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dimethyl fumarate  (ISO)
dimethylarsinic acid  (ISO)
divanadium pentaoxide  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fluoranthene  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fructose  (EXP)
fulvestrant  (ISO)
furan  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glucose  (EXP)
glyphosate  (EXP)
GW 1929  (EXP)
hexachlorobenzene  (ISO)
indole-3-methanol  (ISO)
isotretinoin  (ISO)
leflunomide  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
mangiferin  (EXP)
mercury atom  (EXP)
mercury dichloride  (EXP)
mercury(0)  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-N-nitrosourea  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
oxaliplatin  (ISO)
p-menthan-3-ol  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (ISO)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
puromycin  (ISO)
pyrrolidine dithiocarbamate  (ISO)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
Ro 41-5253  (ISO)
ruxolitinib  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
simvastatin  (EXP)
sodium arsenite  (EXP)
sotorasib  (ISO)
SR 144528  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (EXP)
tetrachloromethane  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
trametinib  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
trovafloxacin  (EXP,ISO)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (ISO)
canonical NF-kappaB signal transduction  (ISO)
CD8-positive, alpha-beta T cell differentiation  (IMP)
cellular response to exogenous dsRNA  (ISO)
cellular response to interferon-beta  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to peptide hormone stimulus  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to tumor necrosis factor  (ISO)
cellular response to type II interferon  (ISO)
defense response to virus  (IMP,ISO)
female pregnancy  (ISO)
immune system process  (IBA)
innate immune response  (IEA)
negative regulation of DNA-templated transcription  (IDA,ISO)
negative regulation of regulatory T cell differentiation  (IMP)
negative regulation of T-helper 2 cell differentiation  (TAS)
negative regulation of tyrosine phosphorylation of STAT protein  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of DNA-templated transcription  (IDA,IMP,ISO)
positive regulation of interferon-beta production  (ISO)
positive regulation of interleukin-12 production  (IDA,IMP)
positive regulation of natural killer cell differentiation  (TAS)
positive regulation of T-helper 1 cell differentiation  (TAS)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
positive regulation of type I interferon production  (IMP)
regulation of adaptive immune response  (TAS)
regulation of CD8-positive, alpha-beta T cell proliferation  (IMP)
regulation of cell cycle  (ISO)
regulation of DNA-templated transcription  (IEA)
regulation of gene expression  (IMP)
regulation of innate immune response  (TAS)
regulation of MyD88-dependent toll-like receptor signaling pathway  (IMP)
regulation of transcription by RNA polymerase II  (IBA,ISO)
response to growth hormone  (ISO)
toll-like receptor 3 signaling pathway  (ISO)
transcription by RNA polymerase II  (IDA)
type II interferon-mediated signaling pathway  (IMP)

Cellular Component
chromatin  (ISO)
cytoplasm  (IDA)
nucleus  (IBA,IC,IDA,IMP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell physiology  (IAGP)
abnormal circulating alanine transaminase level  (IAGP)
abnormal circulating interleukin-10 level  (IAGP)
abnormal circulating interleukin-4 level  (IAGP)
abnormal cytokine level  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal DNA repair  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal immunoglobulin level  (IAGP)
abnormal lymphocyte physiology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal response to infection  (IAGP)
abnormal skin condition  (IAGP)
abnormal splenocyte morphology  (IAGP)
abnormal T cell morphology  (IAGP)
abnormal T cell number  (IAGP)
abnormal T cell proliferation  (IAGP)
abnormal thymus cell ratio  (IAGP)
abnormal vascular wound healing  (IAGP)
decreased anti-double stranded DNA antibody level  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating interferon-gamma level  (IAGP)
decreased circulating interleukin-2 level  (IAGP)
decreased interferon-alpha secretion  (IEA)
decreased interferon-beta secretion  (IEA)
decreased interferon-gamma secretion  (IAGP)
decreased NK cell number  (IEA)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased susceptibility to induced arthritis  (IAGP)
decreased tumor-free survival time  (IAGP)
glomerulonephritis  (IAGP)
impaired natural killer cell mediated cytotoxicity  (IEA)
increased anti-double stranded DNA antibody level  (IAGP)
increased B-1 B cell number  (IEA)
increased CD4-positive, alpha-beta T cell number  (IAGP)
increased circulating interferon-gamma level  (IAGP)
increased circulating interleukin-13 level  (IAGP)
increased circulating interleukin-3 level  (IAGP)
increased circulating interleukin-4 level  (IAGP)
increased circulating interleukin-5 level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased double-positive T cell number  (IAGP)
increased hemangiosarcoma incidence  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased lymphoma incidence  (IAGP)
increased susceptibility to Herpesvirales infection  (IEA)
increased susceptibility to Poxviridae infection  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
increased T-helper 2 cell number  (IAGP)
increased teratoma incidence  (IAGP)
increased tumor incidence  (IAGP)
increased urine protein level  (IAGP)
no abnormal phenotype detected  (IAGP)
premature death  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Expression of the nitric oxide synthase 2 gene is not essential for early control of Mycobacterium tuberculosis in the murine lung. Cooper AM, etal., Infect Immun. 2000 Dec;68(12):6879-82.
2. Taxol activates inducible nitric oxide synthase in rat astrocytes: the role of MAP kinases and NF-kappaB. Cvetkovic I, etal., Cell Mol Life Sci. 2004 May;61(10):1167-75.
3. Type I interferons and IRF-1 play a critical role in the control of a gammaherpesvirus infection. Dutia BM, etal., Virology. 1999 Sep 1;261(2):173-9.
4. Interferon regulatory factor 1 tryptophan 11 to arginine point mutation abolishes DNA binding. Eason DD, etal., Biochim Biophys Acta. 1999 Jul 7;1446(1-2):140-4.
5. Differential expression and signaling of IFN-gamma in the conjunctiva between Lewis and Brown Norway rats. Fukushima A, etal., Microbiol Immunol. 2003;47(10):785-96.
6. Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice. Guidotti LG, etal., J Virol. 2002 Mar;76(6):2617-21. doi: 10.1128/jvi.76.6.2617-2621.2002.
7. In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium. Kelley TJ and Elmer HL, J Clin Invest. 2000 Aug;106(3):403-10.
8. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
9. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
10. MGDs mouse GO annotations MGD data from the GO Consortium
11. MGD IEA MGD IEA
12. STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation. Moore F, etal., J Biol Chem. 2011 Jan 14;286(2):929-41. Epub 2010 Oct 27.
13. Mutation screening of interferon regulatory factor 1 gene (IRF-1) as a candidate gene for atopy/asthma. Noguchi E, etal., Clin Exp Allergy. 2000 Nov;30(11):1562-7.
14. Functionally inactivating point mutation in the tumor-suppressor IRF-1 gene identified in human gastric cancer. Nozawa H, etal., Int J Cancer. 1998 Aug 12;77(4):522-7.
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
18. Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia. Raghavendra Rao VL, etal., J Neurochem 2002 Dec;83(5):1072-86.
19. Traumatic brain injury-induced acute gene expression changes in rat cerebral cortex identified by GeneChip analysis. Raghavendra Rao VL, etal., J Neurosci Res. 2003 Jan 15;71(2):208-19.
20. Genetic basis for adverse events after smallpox vaccination. Reif DM, etal., J Infect Dis. 2008 Jul 1;198(1):16-22. doi: 10.1086/588670.
21. Mouse MP Annotation Import Pipeline RGD automated import pipeline
22. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
24. Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. Sampath D, etal., J Clin Invest. 1999 May;103(9):1353-61.
25. Molecular classification of spontaneous endometrial adenocarcinomas in BDII rats. Samuelson E, etal., Endocr Relat Cancer. 2009 Mar;16(1):99-111. Epub 2008 Dec 15.
26. Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. Silverstein DM, etal., Kidney Int. 2003 Jul;64(1):25-35.
27. GeneChip analysis after acute spinal cord injury in rat. Song G, etal., J Neurochem. 2001 Nov;79(4):804-15.
28. Activation of type II alveolar epithelial cells during acute endotoxemia. Sunil VR, etal., Am J Physiol Lung Cell Mol Physiol. 2002 Apr;282(4):L872-80.
29. [Transcription factors in spinal dorsal root ganglion in rats recurrently infected with respiratory syncytial virus]. Tan H, etal., Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Dec;34(12):1189-95.
30. Association of interferon-gamma and interferon regulatory factor 1 polymorphisms with asthma in a family-based association study in Taiwan. Wang TN, etal., Clin Exp Allergy. 2006 Sep;36(9):1147-52.
31. Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1. Wieland CW, etal., Infect Immun. 2002 Mar;70(3):1352-8.
Additional References at PubMed
PMID:1296455   PMID:1358285   PMID:1442307   PMID:2111015   PMID:2475256   PMID:2911367   PMID:3409321   PMID:7510419   PMID:7567467   PMID:7636205   PMID:7650042   PMID:7654369  
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PMID:9472983   PMID:9551885   PMID:9754575   PMID:9850859   PMID:9973388   PMID:9989987   PMID:10225884   PMID:10346812   PMID:10349636   PMID:10364426   PMID:10415056   PMID:10421776  
PMID:10438942   PMID:10477397   PMID:10524230   PMID:10586082   PMID:10655497   PMID:10704283   PMID:10859338   PMID:10934221   PMID:11034406   PMID:11042159   PMID:11076861   PMID:11160382  
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PMID:16484540   PMID:16541466   PMID:16707500   PMID:16791898   PMID:16966383   PMID:17018642   PMID:17159910   PMID:17170083   PMID:17200147   PMID:17227910   PMID:17273999   PMID:17293456  
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PMID:19075017   PMID:19201871   PMID:19429811   PMID:19430477   PMID:19443641   PMID:19652017   PMID:19720760   PMID:19756487   PMID:20059953   PMID:20083668   PMID:20131404   PMID:20194591  
PMID:20308629   PMID:20412781   PMID:20422028   PMID:20435892   PMID:20451243   PMID:20599664   PMID:20624945   PMID:20631312   PMID:20637660   PMID:20856174   PMID:21267068   PMID:21282509  
PMID:21480215   PMID:21624938   PMID:21653838   PMID:21677750   PMID:21725055   PMID:21820332   PMID:21873635   PMID:21900395   PMID:21903422   PMID:21909274   PMID:22042864   PMID:22185785  
PMID:22229156   PMID:22252317   PMID:22266972   PMID:22345458   PMID:22366192   PMID:22464096   PMID:22514347   PMID:22636321   PMID:22777843   PMID:22896628   PMID:22962685   PMID:22973039  
PMID:22988430   PMID:23154982   PMID:23326354   PMID:23383295   PMID:23444404   PMID:23467089   PMID:23554911   PMID:23623383   PMID:23657854   PMID:23853600   PMID:23863621   PMID:23903655  
PMID:23975864   PMID:24130180   PMID:24140644   PMID:24214980   PMID:24412152   PMID:24464131   PMID:24493010   PMID:24532583   PMID:24675692   PMID:24719409   PMID:24732887   PMID:24793404  
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PMID:32245826   PMID:32321819   PMID:32404986   PMID:32428860   PMID:32517688   PMID:32553121   PMID:32554929   PMID:32853398   PMID:32938919   PMID:32968282   PMID:33067530   PMID:33137133  
PMID:33203755   PMID:33238123   PMID:33278357   PMID:33419764   PMID:33424012   PMID:33479228   PMID:34244313   PMID:34346769   PMID:34365659   PMID:34426111   PMID:34536158   PMID:34658101  
PMID:34694641   PMID:34916189   PMID:35315772   PMID:35462787   PMID:35493520   PMID:35852463   PMID:35864246   PMID:35972291   PMID:36169331   PMID:36175404   PMID:36516771   PMID:36736301  
PMID:36857175   PMID:37001504   PMID:37557956   PMID:37611494   PMID:37889967   PMID:38194130  


Genomics

Comparative Map Data
Irf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,660,841 - 53,669,200 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,660,841 - 53,669,200 (+)EnsemblGRCm39 Ensembl
GRCm381153,770,014 - 53,778,374 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,770,014 - 53,778,374 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,583,516 - 53,591,876 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,613,501 - 53,620,746 (+)NCBIMGSCv36mm8
Celera1158,349,840 - 58,358,199 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1132.0NCBI
IRF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,481,609 - 132,490,773 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,440,440 - 132,508,719 (-)EnsemblGRCh38hg38GRCh38
GRCh375131,817,301 - 131,826,465 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,846,679 - 131,854,326 (-)NCBINCBI36Build 36hg18NCBI36
Build 345131,846,683 - 131,854,326NCBI
Celera5127,947,368 - 127,956,530 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,009,541 - 127,018,697 (-)NCBIHuRef
CHM1_15131,250,016 - 131,259,179 (-)NCBICHM1_1
T2T-CHM13v2.05133,001,395 - 133,010,551 (-)NCBIT2T-CHM13v2.0
Irf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,417,935 - 38,424,946 (+)NCBIGRCr8
mRatBN7.21037,917,155 - 37,924,166 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,916,670 - 37,924,166 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1042,609,084 - 42,616,097 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01042,099,164 - 42,106,177 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,602,877 - 37,609,890 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01039,109,530 - 39,116,532 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1039,109,522 - 39,116,531 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,891,468 - 38,898,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,220,600 - 39,227,602 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11039,229,846 - 39,236,848 (+)NCBI
Celera1037,260,559 - 37,267,561 (+)NCBICelera
RH 3.4 Map10405.3RGD
Cytogenetic Map10q22NCBI
Irf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554083,880,155 - 3,887,973 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554083,882,282 - 3,887,965 (-)NCBIChiLan1.0ChiLan1.0
IRF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24127,800,658 - 127,808,444 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15125,938,753 - 125,947,988 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05127,903,887 - 127,913,843 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15134,066,250 - 134,075,035 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,067,441 - 134,075,035 (-)Ensemblpanpan1.1panPan2
IRF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,773,801 - 20,781,106 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,760,120 - 20,781,608 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,575,525 - 19,582,746 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01121,559,527 - 21,566,744 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1121,559,526 - 21,566,930 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11120,278,269 - 20,285,484 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01120,126,105 - 20,133,315 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01120,768,242 - 20,775,474 (-)NCBIUU_Cfam_GSD_1.0
Irf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,683,543 - 115,690,876 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366472,686,414 - 2,693,636 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366472,686,247 - 2,693,633 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,776,129 - 134,783,801 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,776,122 - 134,783,646 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,229,799 - 140,252,658 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2q24-q29NCBI
IRF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,309,058 - 35,317,765 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,307,772 - 35,316,763 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603442,627,248 - 42,635,033 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473339,596,501 - 39,603,526 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473339,596,565 - 39,603,428 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Irf1
189 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2337
Count of miRNA genes:762
Interacting mature miRNAs:1003
Transcripts:ENSMUST00000019043, ENSMUST00000108920, ENSMUST00000108922, ENSMUST00000123376, ENSMUST00000128336, ENSMUST00000133291, ENSMUST00000138913, ENSMUST00000140866, ENSMUST00000142221, ENSMUST00000153054
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse

Markers in Region
RH136336  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381153,776,808 - 53,776,997UniSTSGRCm38
MGSCv371153,590,310 - 53,590,499UniSTSGRCm37
Celera1158,356,633 - 58,356,822UniSTS
Cytogenetic Map11B1.3UniSTS
PMC15548P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381153,776,806 - 53,777,106UniSTSGRCm38
MGSCv371153,590,308 - 53,590,608UniSTSGRCm37
Celera1158,356,631 - 58,356,931UniSTS
Cytogenetic Map11B1.3UniSTS
Irf1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
cM Map1129.0UniSTS
Irf1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
cM Map1129.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001159393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001159396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK152005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY225160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE950981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY266109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY328342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M21065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M21066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OL792763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000019043   ⟹   ENSMUSP00000019043
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,661,321 - 53,668,149 (+)Ensembl
GRCm38.p6 Ensembl1153,770,495 - 53,777,323 (+)Ensembl
RefSeq Acc Id: ENSMUST00000108920   ⟹   ENSMUSP00000104548
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,660,841 - 53,668,149 (+)Ensembl
GRCm38.p6 Ensembl1153,770,014 - 53,777,323 (+)Ensembl
RefSeq Acc Id: ENSMUST00000108922   ⟹   ENSMUSP00000104550
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,660,878 - 53,669,200 (+)Ensembl
GRCm38.p6 Ensembl1153,770,051 - 53,778,374 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123376   ⟹   ENSMUSP00000122101
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,661,313 - 53,665,020 (+)Ensembl
GRCm38.p6 Ensembl1153,770,487 - 53,774,194 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128336
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,660,898 - 53,667,204 (+)Ensembl
GRCm38.p6 Ensembl1153,770,071 - 53,776,378 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133291   ⟹   ENSMUSP00000116656
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,661,335 - 53,664,783 (+)Ensembl
GRCm38.p6 Ensembl1153,770,509 - 53,773,957 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138913   ⟹   ENSMUSP00000118314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,661,303 - 53,663,764 (+)Ensembl
GRCm38.p6 Ensembl1153,770,477 - 53,772,938 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140866   ⟹   ENSMUSP00000114315
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,660,875 - 53,665,929 (+)Ensembl
GRCm38.p6 Ensembl1153,770,048 - 53,775,103 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142221   ⟹   ENSMUSP00000118795
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,660,932 - 53,664,911 (+)Ensembl
GRCm38.p6 Ensembl1153,770,105 - 53,774,085 (+)Ensembl
RefSeq Acc Id: ENSMUST00000153054
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,663,979 - 53,664,956 (+)Ensembl
GRCm38.p6 Ensembl1153,773,153 - 53,774,130 (+)Ensembl
RefSeq Acc Id: NM_001159393   ⟹   NP_001152865
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,660,841 - 53,669,200 (+)NCBI
GRCm381153,770,014 - 53,778,374 (+)NCBI
MGSCv371153,583,516 - 53,591,876 (+)RGD
Celera1158,349,840 - 58,358,199 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001159396   ⟹   NP_001152868
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,661,299 - 53,668,150 (+)NCBI
GRCm381153,770,473 - 53,777,324 (+)NCBI
MGSCv371153,583,516 - 53,591,876 (+)RGD
Celera1158,349,840 - 58,358,199 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_008390   ⟹   NP_032416
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,660,841 - 53,668,150 (+)NCBI
GRCm381153,770,014 - 53,777,324 (+)NCBI
MGSCv371153,583,516 - 53,591,876 (+)RGD
Celera1158,349,840 - 58,358,199 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036156347   ⟹   XP_036012240
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,662,114 - 53,668,145 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032416   ⟸   NM_008390
- Peptide Label: isoform a
- UniProtKB: P15314 (UniProtKB/Swiss-Prot),   Q5SX13 (UniProtKB/TrEMBL),   Q4FK18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001152865   ⟸   NM_001159393
- Peptide Label: isoform b
- UniProtKB: Q3U5M1 (UniProtKB/TrEMBL),   Q4FK18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001152868   ⟸   NM_001159396
- Peptide Label: isoform a
- UniProtKB: P15314 (UniProtKB/Swiss-Prot),   Q5SX13 (UniProtKB/TrEMBL),   Q4FK18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000118314   ⟸   ENSMUST00000138913
RefSeq Acc Id: ENSMUSP00000116656   ⟸   ENSMUST00000133291
RefSeq Acc Id: ENSMUSP00000114315   ⟸   ENSMUST00000140866
RefSeq Acc Id: ENSMUSP00000104548   ⟸   ENSMUST00000108920
RefSeq Acc Id: ENSMUSP00000104550   ⟸   ENSMUST00000108922
RefSeq Acc Id: ENSMUSP00000122101   ⟸   ENSMUST00000123376
RefSeq Acc Id: ENSMUSP00000118795   ⟸   ENSMUST00000142221
RefSeq Acc Id: ENSMUSP00000019043   ⟸   ENSMUST00000019043
RefSeq Acc Id: XP_036012240   ⟸   XM_036156347
- Peptide Label: isoform X1
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P15314-F1-model_v2 AlphaFold P15314 1-329 view protein structure

Promoters
RGD ID:6821115
Promoter ID:MM_KWN:7403
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001159393,   NM_001159396,   NM_008390,   NM_008390_IRF1,   OTTMUST00000012565,   OTTMUST00000012566,   OTTMUST00000012567,   OTTMUST00000012568,   OTTMUST00000044066,   OTTMUST00000071566,   UC007IWX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361153,582,896 - 53,583,727 (+)MPROMDB
RGD ID:6821118
Promoter ID:MM_KWN:7404
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000012562
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361153,586,171 - 53,587,097 (+)MPROMDB
RGD ID:8674630
Promoter ID:EPDNEW_M15345
Type:initiation region
Name:Irf1_1
Description:Mus musculus interferon regulatory factor 1 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15346  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381153,770,051 - 53,770,111EPDNEW
RGD ID:8674634
Promoter ID:EPDNEW_M15346
Type:multiple initiation site
Name:Irf1_2
Description:Mus musculus interferon regulatory factor 1 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15345  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381153,770,500 - 53,770,560EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96590 AgrOrtholog
Ensembl Genes ENSMUSG00000018899 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000019043 ENTREZGENE
  ENSMUST00000019043.13 UniProtKB/Swiss-Prot
  ENSMUST00000108920 ENTREZGENE
  ENSMUST00000108920.10 UniProtKB/Swiss-Prot
  ENSMUST00000108922 ENTREZGENE
  ENSMUST00000108922.9 UniProtKB/TrEMBL
  ENSMUST00000123376.8 UniProtKB/TrEMBL
  ENSMUST00000133291.3 UniProtKB/TrEMBL
  ENSMUST00000138913.8 UniProtKB/TrEMBL
  ENSMUST00000140866.9 UniProtKB/TrEMBL
  ENSMUST00000142221.9 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Interferon_reg_fac_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interferon_reg_fact_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF1/IRF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16362 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96590 ENTREZGENE
NCBI Gene 16362 ENTREZGENE
PANTHER INTERFERON REGULATORY FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11949:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Irf1 PhenoGen
PIRSF IFN_RF1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS INTFRNREGFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IRF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8Y5B9_MOUSE UniProtKB/TrEMBL
  D6RH71_MOUSE UniProtKB/TrEMBL
  IRF1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U5M1 ENTREZGENE, UniProtKB/TrEMBL
  Q4FK18 ENTREZGENE, UniProtKB/TrEMBL
  Q5SX13 ENTREZGENE, UniProtKB/TrEMBL
  Q5SX14_MOUSE UniProtKB/TrEMBL
  Q5SX15_MOUSE UniProtKB/TrEMBL
  Q5SX16_MOUSE UniProtKB/TrEMBL