Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Itgb5 (integrin beta 5) Mus musculus
Symbol: Itgb5
Name: integrin beta 5
RGD ID: 1617621
Description: Exhibits integrin binding activity. Involved in integrin-mediated signaling pathway; stress fiber assembly; and transforming growth factor beta receptor signaling pathway. Localizes to several cellular components, including focal adhesion; glutamatergic synapse; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Orthologous to human ITGB5 (integrin subunit beta 5); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [b]-5; [b]5; [b]5A; [b]5B; AA475909; AI874634; beta-; beta-5; beta5; ESTM2; ESTM23; integrin beta-5
Homo sapiens (human) : ITGB5 (integrin subunit beta 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itgb5 (integrin subunit beta 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb5 (integrin subunit beta 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB5 (integrin subunit beta 5)
Canis lupus familiaris (dog) : ITGB5 (integrin subunit beta 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb5 (integrin subunit beta 5)
Sus scrofa (pig) : ITGB5 (integrin subunit beta 5)
Chlorocebus sabaeus (African green monkey) : ITGB5 (integrin subunit beta 5)
Heterocephalus glaber (naked mole-rat) : Itgb5 (integrin subunit beta 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391633,650,035 - 33,769,708 (+)NCBI
GRCm381633,829,665 - 33,949,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,829,665 - 33,949,338 (+)EnsemblGRCm38mm10GRCm38
MGSCv371633,829,751 - 33,949,424 (+)NCBIGRCm37mm9NCBIm37
MGSCv361633,749,506 - 33,868,893 (+)NCBImm8
Celera1634,313,798 - 34,433,456 (+)NCBICelera
Cytogenetic Map16B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Itgb5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1617621
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.