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Gene: Itgb5 (integrin beta 5) Mus musculus
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Symbol: Itgb5
Name: integrin beta 5
RGD ID: 1617621
Description: Exhibits integrin binding activity. Involved in integrin-mediated signaling pathway; stress fiber assembly; and transforming growth factor beta receptor signaling pathway. Localizes to several cellular components, including focal adhesion; glutamatergic synapse; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Orthologous to human ITGB5 (integrin subunit beta 5); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [b]-5; [b]5; [b]5A; [b]5B; AA475909; AI874634; beta-; beta-5; beta5; ESTM2; ESTM23; integrin beta-5
Orthologs:
Homo sapiens (human) : ITGB5 (integrin subunit beta 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itgb5 (integrin subunit beta 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb5 (integrin subunit beta 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB5 (integrin subunit beta 5)
Canis lupus familiaris (dog) : ITGB5 (integrin subunit beta 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb5 (integrin subunit beta 5)
Sus scrofa (pig) : ITGB5 (integrin subunit beta 5)
Chlorocebus sabaeus (African green monkey) : ITGB5 (integrin subunit beta 5)
Heterocephalus glaber (naked mole-rat) : Itgb5 (integrin subunit beta 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,650,035 - 33,769,708 (+)NCBI
GRCm381633,829,665 - 33,949,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,829,665 - 33,949,338 (+)EnsemblGRCm38mm10GRCm38
MGSCv371633,829,751 - 33,949,424 (+)NCBIGRCm37mm9NCBIm37
MGSCv361633,749,506 - 33,868,893 (+)NCBImm8
Celera1634,313,798 - 34,433,456 (+)NCBICelera
Cytogenetic Map16B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Itgb5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1617621
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.