Maf (MAF bZIP transcription factor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Maf (MAF bZIP transcription factor) Mus musculus
Analyze
Symbol: Maf
Name: MAF bZIP transcription factor
RGD ID: 735352
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within several processes, including lens fiber cell differentiation; regulation of chondrocyte differentiation; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and zeugopod. Used to study cataract 21 multiple types. Human ortholog(s) of this gene implicated in Ayme-Gripp syndrome; cataract; and cataract 21 multiple types. Orthologous to human MAF (MAF bZIP transcription factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810401A20Rik; A230108G15Rik; avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog; avian musculoaponeurotic fibrosarcoma oncogene homolog; AW047063; c-ma; c-maf; c-Maf long form; proto-oncogene c-maf; transcription factor Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398116,429,992 - 116,433,633 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8116,409,681 - 116,434,533 (-)EnsemblGRCm39 Ensembl
GRCm388115,703,253 - 115,706,894 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8115,682,942 - 115,707,794 (-)EnsemblGRCm38mm10GRCm38
MGSCv378118,227,153 - 118,230,794 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368118,589,230 - 118,592,871 (-)NCBIMGSCv36mm8
Celera8119,915,403 - 119,918,981 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map862.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-butoxyethanol  (EXP)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-dichloroaniline  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-vinylcyclohexene dioxide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
casticin  (EXP)
cefaloridine  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (EXP)
chromium(6+)  (EXP)
cisplatin  (EXP)
clofibric acid  (ISO)
colforsin daropate hydrochloride  (ISO)
cyclosporin A  (EXP,ISO)
dapsone  (ISO)
deoxycholic acid  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzalutamide  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
flavonoids  (ISO)
fluoranthene  (EXP)
fonofos  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP)
irinotecan  (ISO)
isoflavones  (ISO)
isoprenaline  (ISO)
lipopolysaccharide  (ISO)
lithocholic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
menadione  (ISO)
methimazole  (ISO)
methoxychlor  (EXP)
methylisothiazolinone  (ISO)
methylseleninic acid  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel sulfate  (ISO)
obeticholic acid  (ISO)
oxazepam  (EXP)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phlorizin  (EXP)
pirinixic acid  (EXP,ISO)
progesterone  (ISO)
propiconazole  (EXP)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
SB 431542  (ISO)
Sinomenine  (EXP)
sodium arsenite  (EXP)
sodium dichromate  (EXP)
Soman  (ISO)
Sunset Yellow FCF  (ISO)
tamoxifen  (ISO)
tartrazine  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tipifarnib  (ISO)
titanium dioxide  (EXP)
Trapidil  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trovafloxacin  (EXP)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axon morphology  (IAGP)
abnormal blood vessel morphology  (IEA)
abnormal coat/ hair morphology  (IAGP)
abnormal corneal endothelium morphology  (IAGP)
abnormal eating behavior  (IAGP)
abnormal heart morphology  (IEA)
abnormal kidney morphology  (IAGP)
abnormal lens development  (IAGP)
abnormal lens fiber morphology  (IAGP)
abnormal lens induction  (IAGP)
abnormal lens morphology  (IAGP)
abnormal lens vesicle development  (IAGP)
abnormal liver morphology  (IEA)
abnormal liver size  (IEA)
abnormal Meissner's corpuscle morphology  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal ovary morphology  (IEA)
abnormal pacinian corpuscle morphology  (IAGP)
abnormal placenta morphology  (IEA)
abnormal placenta vasculature  (IEA)
abnormal pupillary reflex  (IAGP)
abnormal spleen morphology  (IEA)
axon degeneration  (IAGP)
cataract  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased nerve conduction velocity  (IAGP)
decreased pacinian corpuscle number  (IAGP)
decreased prepulse inhibition  (IEA)
dilated renal tubule  (IAGP)
edema  (IEA)
embryonic growth retardation  (IEA)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enlarged heart  (IEA)
enlarged kidney  (IEA)
enlarged ovary  (IEA)
enlarged spleen  (IEA)
impaired coordination  (IAGP)
increased circulating bilirubin level  (IEA)
increased cornea thickness  (IAGP)
increased freezing behavior  (IEA)
increased urine glucose level  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
microphthalmia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
nuclear cataract  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
shortened head  (IAGP)
small kidney  (IEA)
small lens  (IAGP)
small liver  (IEA)
small pacinian corpuscles  (IAGP)
small pupil  (IAGP)
small spleen  (IEA)
tremors  (IAGP)
tubular nephritis  (IAGP)
urinary bladder obstruction  (IEA)
weakness  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Comprehensive mutational screening in a cohort of Danish families with hereditary congenital cataract. Hansen L, etal., Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3291-303. doi: 10.1167/iovs.08-3149. Epub 2009 Jan 31.
2. Domain disruption and mutation of the bZIP transcription factor, MAF, associated with cataract, ocular anterior segment dysgenesis and coloboma. Jamieson RV, etal., Hum Mol Genet 2002 Jan 1;11(1):33-42.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Identification of a novel missense mutation of MAF in a Japanese family with congenital cataract by whole exome sequencing: a clinical report and review of literature. Narumi Y, etal., Am J Med Genet A. 2014 May;164A(5):1272-6. doi: 10.1002/ajmg.a.36433. Epub 2014 Mar 24.
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Mouse chromosomal location of three epithelial sodium channel subunit genes and an apical sodium chloride cotransporter gene. Pathak BG, etal., Genomics 1996 Apr 1;33(1):124-7.
11. A heterozygous c-Maf transactivation domain mutation causes congenital cataract and enhances target gene activation. Perveen R, etal., Hum Mol Genet. 2007 May 1;16(9):1030-8. Epub 2007 Mar 20.
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Multiple mouse chromosomal loci for dynein-based motility. Vaughan KT, etal., Genomics 1996 Aug 15;36(1):29-38.
Additional References at PubMed
PMID:7789972   PMID:7799931   PMID:8164679   PMID:8211130   PMID:8265578   PMID:8844497   PMID:8889548   PMID:9047395   PMID:9224592   PMID:10097114   PMID:10349636   PMID:10383433  
PMID:10403649   PMID:10603348   PMID:10699374   PMID:10885750   PMID:11042159   PMID:11076861   PMID:11233530   PMID:11840349   PMID:11850820   PMID:12150890   PMID:12271139   PMID:12381733  
PMID:12421951   PMID:12477932   PMID:12551916   PMID:12620964   PMID:12835653   PMID:12917329   PMID:14512017   PMID:14707122   PMID:14742445   PMID:15187104   PMID:15249232   PMID:15452066  
PMID:15618518   PMID:15728480   PMID:15749884   PMID:15781580   PMID:15790681   PMID:15832295   PMID:15845902   PMID:16023139   PMID:16141072   PMID:16141073   PMID:16162653   PMID:16325892  
PMID:16343439   PMID:16424013   PMID:16446698   PMID:16516881   PMID:16580660   PMID:16675956   PMID:16785233   PMID:16890189   PMID:17360442   PMID:17493607   PMID:17823980   PMID:17892401  
PMID:17901057   PMID:18287559   PMID:18455718   PMID:18652817   PMID:18757513   PMID:19098919   PMID:19334279   PMID:19386638   PMID:19414009   PMID:19414776   PMID:19515997   PMID:19539733  
PMID:19553542   PMID:19570826   PMID:19570848   PMID:19623612   PMID:19624757   PMID:19627984   PMID:19877281   PMID:19892988   PMID:20042469   PMID:20060689   PMID:20127678   PMID:20181838  
PMID:20484573   PMID:20510229   PMID:20534675   PMID:20676095   PMID:20877012   PMID:21224354   PMID:21255566   PMID:21267068   PMID:21362551   PMID:21402704   PMID:21460847   PMID:21504908  
PMID:21628412   PMID:21743007   PMID:21795542   PMID:21873635   PMID:21998302   PMID:22001828   PMID:22120711   PMID:22173065   PMID:22275127   PMID:22345400   PMID:22491411   PMID:22514301  
PMID:22798672   PMID:22827438   PMID:22972715   PMID:23021777   PMID:23312518   PMID:23334579   PMID:23426945   PMID:23460268   PMID:23482492   PMID:24140542   PMID:24151333   PMID:24161570  
PMID:24319262   PMID:24445679   PMID:24472646   PMID:24742460   PMID:24821970   PMID:24912173   PMID:24952961   PMID:25073789   PMID:25268479   PMID:25763640   PMID:25792196   PMID:25912440  
PMID:25993510   PMID:26138486   PMID:26139534   PMID:26554594   PMID:26719333   PMID:26825710   PMID:26969892   PMID:26996125   PMID:27022145   PMID:27596755   PMID:27631609   PMID:27657450  
PMID:28763805   PMID:29117290   PMID:29127150   PMID:29324782   PMID:29360039   PMID:29414937   PMID:29484383   PMID:29662170   PMID:29748249   PMID:29768210   PMID:29878134   PMID:29899446  
PMID:29907708   PMID:29974486   PMID:30059018   PMID:30538336   PMID:30635555   PMID:30699346   PMID:30728831   PMID:30778241   PMID:30929925   PMID:30992496   PMID:31142588   PMID:31231191  
PMID:31257105   PMID:31278058   PMID:31422869   PMID:31570496   PMID:31945018   PMID:31969659   PMID:32027825   PMID:32039762   PMID:32043969   PMID:32452758   PMID:32627520   PMID:33006313  
PMID:33238123   PMID:33328221   PMID:34007995   PMID:34119483   PMID:34321664   PMID:34502552   PMID:34597123   PMID:35175194   PMID:35364013   PMID:35377797   PMID:35395181   PMID:35467036  
PMID:35613277   PMID:36121415   PMID:36121416   PMID:36504079   PMID:36787192   PMID:36928411   PMID:36947543   PMID:37088263   PMID:37468485   PMID:37566909   PMID:37815917  


Genomics

Comparative Map Data
Maf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398116,429,992 - 116,433,633 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8116,409,681 - 116,434,533 (-)EnsemblGRCm39 Ensembl
GRCm388115,703,253 - 115,706,894 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8115,682,942 - 115,707,794 (-)EnsemblGRCm38mm10GRCm38
MGSCv378118,227,153 - 118,230,794 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368118,589,230 - 118,592,871 (-)NCBIMGSCv36mm8
Celera8119,915,403 - 119,918,981 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map862.61NCBI
MAF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381679,202,622 - 79,600,737 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1679,585,843 - 79,600,737 (-)EnsemblGRCh38hg38GRCh38
GRCh371679,627,735 - 79,634,634 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361678,185,732 - 78,192,112 (-)NCBINCBI36Build 36hg18NCBI36
Build 341678,185,735 - 78,192,112NCBI
Celera1663,926,698 - 63,933,512 (-)NCBICelera
Cytogenetic Map16q23.2NCBI
HuRef1665,384,643 - 65,391,409 (-)NCBIHuRef
CHM1_11681,039,513 - 81,046,247 (-)NCBICHM1_1
T2T-CHM13v2.01685,268,951 - 85,657,071 (-)NCBIT2T-CHM13v2.0
Maf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81960,259,200 - 60,622,145 (-)NCBIGRCr8
mRatBN7.21943,353,867 - 43,713,162 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1943,360,342 - 43,712,365 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1950,534,463 - 50,536,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01951,187,718 - 51,189,656 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01953,428,393 - 53,430,309 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01948,179,826 - 48,200,995 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1948,194,804 - 48,196,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01958,976,694 - 58,999,741 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41945,859,510 - 45,861,454 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11945,864,390 - 45,866,335 (-)NCBI
Celera1943,012,985 - 43,014,923 (-)NCBICelera
Cytogenetic Map19q12NCBI
Maf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555222,514,313 - 2,519,694 (-)NCBIChiLan1.0ChiLan1.0
MAF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21889,333,211 - 89,339,592 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11695,251,476 - 95,257,980 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01660,188,494 - 60,194,871 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11679,618,156 - 79,624,460 (-)NCBIpanpan1.1PanPan1.1panPan2
MAF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1571,965,291 - 71,982,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl571,965,500 - 71,981,735 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha571,912,571 - 71,918,461 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0572,271,569 - 72,277,450 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl572,271,341 - 72,302,366 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1572,211,442 - 72,217,331 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0572,047,056 - 72,052,965 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0572,524,417 - 72,530,335 (+)NCBIUU_Cfam_GSD_1.0
MAF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl68,468,413 - 8,485,030 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.168,468,736 - 8,910,012 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.268,568,594 - 8,571,175 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1565,064,715 - 65,078,972 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604710,795,871 - 10,802,372 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Maf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247467,653,690 - 7,672,404 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Maf
113 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2618
Count of miRNA genes:828
Interacting mature miRNAs:1141
Transcripts:ENSMUST00000069009, ENSMUST00000109104
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871740461124622354Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71740461124622354Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)874126628126826739Mouse
1301766Desp1_mdespair 1 (mouse)Not determined885486208119486373Mouse
1302049Heal1_mwound healing/regeneration 1 (mouse)Not determined886443553120443701Mouse
1301253Skmw2_mskeletal muscle weight 2 (mouse)Not determined886443553120443701Mouse
10045619Heal14_mwound healing/regeneration 14 (mouse)Not determined886443553120443701Mouse
27226796Scvln16_msacral vertebrae length 2, 16 week (mouse)889726628130027694Mouse
1357494Obsty2_mobesity 2 (mouse)Not determined896245241129745061Mouse
12880431Fgf23lq2_mFGF23 serum level QTL 2 (mouse)897626632130127694Mouse
11252141Fdr2_mfat response to dietary restriction 2 (mouse)898390634130127694Mouse
1301481Lith11_mlithogenic gene 11 (mouse)Not determined898563635130127694Mouse
1302105Im1_mImmunoregulatory 1 (mouse)Not determined899828531130127694Mouse
1301080Sluc9_msusceptibility to lung cancer 9 (mouse)Not determined899828531130127694Mouse
4141435Fbtq3_mfemoral bone trait QTL 3 (mouse)Not determined8100965309130127694Mouse
1301316Dntcs1_mdental caries susceptibility 1 (mouse)Not determined8103443553127781786Mouse
11532691Sluc38_msusceptibility to lung cancer 38 (mouse)8105033977130127694Mouse
11532692Sluc38a_msusceptibility to lung cancer 38a (mouse)8105033977130127694Mouse
14746994Manh65_mmandible shape 65 (mouse)8106489629130127694Mouse
10412273Fcd1_mfunctional capillary density 1 (mouse)Not determined8110415083130127694Mouse
10412274Leci1_mleukocyte endothelial cell interactions 1 (mouse)Not determined8110415083130127694Mouse
12904938Edlmmq7_mextensor digitorum longus muscle mass QTL 7 (mouse)8111481497130127694Mouse
12904960Gmmq6_mgastrocnemius muscle mass QTL 6 (mouse)8111481497130127694Mouse
4141546Mrdq3_mmodifier of retinal degeneration QTL 3 (mouse)Not determined114439420126055880Mouse

Markers in Region
AW047063  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388115,682,994 - 115,683,092UniSTSGRCm38
MGSCv378118,206,894 - 118,206,992UniSTSGRCm37
Celera8119,895,224 - 119,895,322UniSTS
Cytogenetic Map8E1UniSTS
cM Map861.0UniSTS
Whitehead/MRC_RH81387.82UniSTS
Maf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381576,353,378 - 76,353,610UniSTSGRCm38
MGSCv378118,229,574 - 118,229,845UniSTSGRCm37
Celera1577,853,439 - 77,853,671UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map8E1UniSTS
cM Map861.0UniSTS
cM Map861.0UniSTS
D19Wox13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388115,705,490 - 115,705,746UniSTSGRCm38
MGSCv378118,229,390 - 118,229,646UniSTSGRCm37
Celera8119,917,640 - 119,917,888UniSTS
Cytogenetic Map8E1UniSTS
cM Map861.0UniSTS
Maf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388115,705,674 - 115,705,945UniSTSGRCm38
MGSCv378118,229,574 - 118,229,845UniSTSGRCm37
Celera8119,917,816 - 119,918,087UniSTS
Cytogenetic Map8E1UniSTS
cM Map861.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000069009   ⟹   ENSMUSP00000067704
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8116,409,681 - 116,433,835 (-)Ensembl
GRCm38.p6 Ensembl8115,682,942 - 115,707,096 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109104   ⟹   ENSMUSP00000104732
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8116,428,174 - 116,434,533 (-)Ensembl
GRCm38.p6 Ensembl8115,701,435 - 115,707,794 (-)Ensembl
RefSeq Acc Id: NM_001025577   ⟹   NP_001020748
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398116,429,992 - 116,433,633 (-)NCBI
GRCm388115,703,253 - 115,706,894 (-)ENTREZGENE
MGSCv378118,227,153 - 118,230,794 (-)RGD
Celera8119,915,403 - 119,918,981 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001020748 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB32820 (Get FASTA)   NCBI Sequence Viewer  
  BAE21007 (Get FASTA)   NCBI Sequence Viewer  
  EDL11560 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000067704.7
  ENSMUSP00000104732
  ENSMUSP00000104732.2
GenBank Protein P54843 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001020748   ⟸   NM_001025577
- UniProtKB: Q3V1Z2 (UniProtKB/Swiss-Prot),   Q4QY62 (UniProtKB/Swiss-Prot),   P54843 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000104732   ⟸   ENSMUST00000109104
RefSeq Acc Id: ENSMUSP00000067704   ⟸   ENSMUST00000069009
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P54843-F1-model_v2 AlphaFold P54843 1-370 view protein structure

Promoters
RGD ID:8668365
Promoter ID:EPDNEW_M12213
Type:initiation region
Name:Maf_1
Description:Mus musculus avian musculoaponeurotic fibrosarcoma oncogene homolog, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm388115,706,981 - 115,707,041EPDNEW
RGD ID:6843425
Promoter ID:MM_KWN:55842
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001025577,   OTTMUST00000061393
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv368118,227,256 - 118,231,797 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96909 AgrOrtholog
Ensembl Genes ENSMUSG00000055435 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000069009.7 UniProtKB/Swiss-Prot
  ENSMUST00000109104 ENTREZGENE
  ENSMUST00000109104.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
InterPro bZIP UniProtKB/Swiss-Prot
  bZIP_Maf UniProtKB/Swiss-Prot
  bZIP_sf UniProtKB/Swiss-Prot
  Maf_TF_N UniProtKB/Swiss-Prot
  TF_DNA-bd_sf UniProtKB/Swiss-Prot
  Transciption_factor_Maf_fam UniProtKB/Swiss-Prot
KEGG Report mmu:17132 UniProtKB/Swiss-Prot
MGD MGI:96909 ENTREZGENE
NCBI Gene 17132 ENTREZGENE
PANTHER PTHR10129 UniProtKB/Swiss-Prot
  PTHR10129:SF9 UniProtKB/Swiss-Prot
Pfam bZIP_Maf UniProtKB/Swiss-Prot
  Maf_N UniProtKB/Swiss-Prot
PhenoGen Maf PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot
SMART BRLZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot
  SSF57959 UniProtKB/Swiss-Prot
UniProt MAF_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3V1Z2 ENTREZGENE
  Q4QY62 ENTREZGENE
UniProt Secondary Q3V1Z2 UniProtKB/Swiss-Prot
  Q4QY62 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-02-28 Maf  MAF bZIP transcription factor  Maf  avian musculoaponeurotic fibrosarcoma oncogene homolog  Symbol and/or name change 5135510 APPROVED
2016-02-02 Maf  avian musculoaponeurotic fibrosarcoma oncogene homolog    avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog  Symbol and/or name change 5135510 APPROVED