(1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PKM mRNA CTD PMID:36331819 (R)-adrenaline multiple interactions ISO RGD:3337 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein CTD PMID:19464573 (R)-adrenaline increases expression EXP 6480464 Epinephrine results in increased expression of PKM protein CTD PMID:36423730 (R)-adrenaline increases expression ISO RGD:737501 6480464 Epinephrine results in increased expression of PKM protein CTD PMID:36423730 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:737501 6480464 o, p'-DDT results in increased expression of PKM mRNA CTD PMID:19371625 1,2,4-trimethylbenzene decreases expression ISO RGD:3337 6480464 pseudocumene results in decreased expression of PKM protein CTD PMID:17337753 1,4-benzoquinone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [quinone results in increased degradation of PKM protein] more ... CTD PMID:25437431 1,4-benzoquinone increases expression ISO RGD:737501 6480464 quinone results in increased expression of PKM protein CTD PMID:30448556 1,4-benzoquinone multiple interactions ISO RGD:737501 6480464 [HIF1A protein co-treated with quinone] results in increased expression of PKM protein CTD PMID:30448556 1-chloro-2,4-dinitrobenzene increases metabolic processing ISO RGD:737501 6480464 Dinitrochlorobenzene results in increased metabolism of PKM protein CTD PMID:29267982 14-Deoxy-11,12-didehydroandrographolide decreases expression ISO RGD:737501 6480464 14-deoxy-11, 12-didehydroandrographolide results in decreased expression of PKM mRNA CTD PMID:22101062 17alpha-ethynylestradiol increases expression ISO RGD:3337 6480464 Ethinyl Estradiol results in increased expression of PKM mRNA CTD PMID:12075121 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of PKM mRNA CTD PMID:19484750 17beta-estradiol multiple interactions ISO RGD:737501 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of and affects the localization of PKM protein] more ... CTD PMID:32078667 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:737501 6480464 Metribolone promotes the reaction [NDRG1 protein binds to PKM protein] CTD PMID:17220478 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO RGD:737501 6480464 2 more ... CTD PMID:31251971 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:737501 6480464 2 more ... CTD PMID:31251971 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:3337 6480464 Tetrachlorodibenzodioxin results in decreased expression of PKM protein CTD PMID:16548065 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3337 6480464 Tetrachlorodibenzodioxin results in increased expression of PKM mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PKM mRNA more ... CTD PMID:19770486 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PKM mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737501 6480464 Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA CTD PMID:23152189 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:737501 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA], alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] CTD PMID:23152189 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:3337 6480464 2 more ... CTD PMID:19954255 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO RGD:3337 6480464 2 more ... CTD PMID:19954255 2,4-dinitrotoluene affects expression ISO RGD:3337 6480464 2, 4-dinitrotoluene affects the expression of PKM mRNA CTD PMID:21346803 2,5-hexanedione increases expression ISO RGD:3337 6480464 2, 5-hexanedione results in increased expression of PKM protein CTD PMID:19033394 2-acetamidofluorene increases expression ISO RGD:3337 6480464 2-Acetylaminofluorene results in increased expression of PKM mRNA, 2-Acetylaminofluorene results in increased expression of PKM protein CTD PMID:17538966 2-deoxy-D-glucose multiple interactions ISO RGD:737501 6480464 Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of PKM protein] CTD PMID:35945655 2-hydroxypropanoic acid increases abundance ISO RGD:737501 6480464 PKM protein results in increased abundance of Lactic Acid CTD PMID:22574221 2-hydroxypropanoic acid increases expression ISO RGD:737501 6480464 Lactic Acid results in increased expression of PKM protein CTD PMID:36336208 2-hydroxypropanoic acid multiple interactions ISO RGD:737501 6480464 Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:36336208 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:737501 6480464 Acetylcysteine inhibits the reaction [3 more ... CTD PMID:28284859 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:737501 6480464 3 more ... CTD PMID:28284859 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression EXP 6480464 3 more ... CTD PMID:27052460 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions EXP 6480464 GW 3965 inhibits the reaction [3 more ... CTD PMID:27052460 3-chloropropane-1,2-diol increases expression ISO RGD:3337 6480464 alpha-Chlorohydrin results in increased expression of PKM protein CTD PMID:26072098 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:737501 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 3-methyladenine multiple interactions ISO RGD:737501 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein], 3-methyladenine inhibits the reaction [Potassium Dichromate results in increased expression of PKM protein] CTD PMID:32569804 more ... 3-phenylprop-2-enal increases metabolic processing ISO RGD:737501 6480464 cinnamaldehyde results in increased metabolism of PKM protein CTD PMID:29267982 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of PKM mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO RGD:737501 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of PKM protein CTD PMID:34186270 4-chlorobiphenyl increases expression ISO RGD:737501 6480464 4-chlorobiphenyl metabolite results in increased expression of PKM mRNA CTD PMID:25417049 4-hydroxynon-2-enal multiple interactions ISO RGD:737501 6480464 4-hydroxy-2-nonenal binds to and results in decreased activity of PKM protein, 4-hydroxy-2-nonenal promotes the reaction [PKM protein binds to PKM protein] CTD PMID:27978618 4-hydroxynon-2-enal affects binding ISO RGD:737501 6480464 4-hydroxy-2-nonenal analog binds to PKM protein CTD PMID:27978618 4-phenylbutyric acid multiple interactions ISO RGD:737501 6480464 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of PKM protein] CTD PMID:32569804 , PMID:36473502 5-aza-2'-deoxycytidine affects methylation ISO RGD:737501 6480464 Decitabine affects the methylation of PKM gene CTD PMID:17630775 5-azacytidine increases expression ISO RGD:737501 6480464 Azacitidine results in increased expression of PKM mRNA CTD PMID:20823114 5-Hydroxyflavone multiple interactions ISO RGD:737501 6480464 5-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 6-Hydroxyflavone multiple interactions ISO RGD:737501 6480464 6-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 7-hydroxyflavone multiple interactions ISO RGD:737501 6480464 7-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 7H-xanthine multiple interactions ISO RGD:3337 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein, [Xanthine co-treated with XDH protein] results in decreased expression of PKM protein CTD PMID:19464573 9-cis-retinoic acid decreases expression ISO RGD:737501 6480464 Alitretinoin results in decreased expression of PKM protein CTD PMID:28886987 9H-xanthine multiple interactions ISO RGD:3337 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein, [Xanthine co-treated with XDH protein] results in decreased expression of PKM protein CTD PMID:19464573 acetamide increases expression ISO RGD:3337 6480464 acetamide results in increased expression of PKM mRNA CTD PMID:31881176 acrolein multiple interactions ISO RGD:737501 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PKM mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PKM mRNA CTD PMID:32699268 acrylamide increases expression ISO RGD:3337 6480464 Acrylamide results in increased expression of PKM mRNA CTD PMID:28959563 aflatoxin B1 decreases expression ISO RGD:737501 6480464 Aflatoxin B1 results in decreased expression of PKM mRNA CTD PMID:22100608 aflatoxin B1 increases expression ISO RGD:737501 6480464 Aflatoxin B1 results in increased expression of PKM mRNA CTD PMID:27153756 aflatoxin B1 increases methylation ISO RGD:737501 6480464 Aflatoxin B1 results in increased methylation of PKM gene CTD PMID:27153756 aldehydo-D-glucose multiple interactions ISO RGD:737501 6480464 Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]] more ... CTD PMID:23086999 more ... aldehydo-D-glucose increases uptake ISO RGD:737501 6480464 PKM protein results in increased uptake of Glucose CTD PMID:22574221 all-trans-retinoic acid increases expression ISO RGD:737501 6480464 Tretinoin results in increased expression of PKM mRNA CTD PMID:15894607 more ... all-trans-retinoic acid decreases expression ISO RGD:737501 6480464 Tretinoin results in decreased expression of PKM protein CTD PMID:28886987 all-trans-retinoic acid multiple interactions ISO RGD:737501 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of PKM mRNA CTD PMID:15894607 alpha-D-galactose multiple interactions ISO RGD:737501 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA] CTD PMID:31654802 alpha-naphthoflavone multiple interactions ISO RGD:737501 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] CTD PMID:23152189 alpha-pinene multiple interactions ISO RGD:737501 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PKM mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PKM mRNA CTD PMID:32699268 ammonium chloride affects expression ISO RGD:3337 6480464 Ammonium Chloride affects the expression of PKM mRNA CTD PMID:16483693 ampicillin increases expression ISO RGD:737501 6480464 Ampicillin results in increased expression of PKM mRNA CTD PMID:21632981 apigenin multiple interactions ISO RGD:737501 6480464 Apigenin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 aristolochic acid A increases expression ISO RGD:737501 6480464 aristolochic acid I results in increased expression of PKM protein CTD PMID:33212167 arsane affects binding ISO RGD:737501 6480464 Arsenic binds to PKM protein CTD PMID:17499915 arsenic atom affects binding ISO RGD:737501 6480464 Arsenic binds to PKM protein CTD PMID:17499915 arsenite(3-) multiple interactions ISO RGD:737501 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PKM protein] CTD PMID:32406909 arsenous acid multiple interactions ISO RGD:737501 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PKM mRNA more ... CTD PMID:15894607 , PMID:31003765 arsenous acid decreases expression ISO RGD:737501 6480464 Arsenic Trioxide results in decreased expression of PKM mRNA, Arsenic Trioxide results in decreased expression of PKM protein CTD PMID:31003765 arsenous acid increases expression ISO RGD:737501 6480464 Arsenic Trioxide results in increased expression of PKM protein CTD PMID:25419056 atorvastatin calcium increases expression ISO RGD:3337 6480464 Atorvastatin results in increased expression of PKM mRNA CTD PMID:27377005 atrazine increases expression ISO RGD:737501 6480464 Atrazine results in increased expression of PKM mRNA CTD PMID:22378314 baicalein increases activity ISO RGD:737501 6480464 baicalein results in increased activity of PKM protein CTD PMID:25388478 baicalin increases activity ISO RGD:737501 6480464 baicalin results in increased activity of PKM protein CTD PMID:25388478 benzo[a]pyrene increases mutagenesis ISO RGD:737501 6480464 Benzo(a)pyrene results in increased mutagenesis of PKM gene CTD PMID:25435355 benzo[a]pyrene increases expression ISO RGD:737501 6480464 Benzo(a)pyrene results in increased expression of PKM mRNA CTD PMID:32234424 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PKM mRNA CTD PMID:19770486 , PMID:32417428 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:737501 6480464 7 more ... CTD PMID:20018196 bifenthrin increases expression EXP 6480464 bifenthrin results in increased expression of PKM mRNA CTD PMID:26071804 bis(2-chloroethyl) sulfide affects expression ISO RGD:3337 6480464 Mustard Gas affects the expression of PKM mRNA CTD PMID:15651846 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of PKM mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of PKM mRNA CTD PMID:30284816 bis(2-ethylhexyl) phthalate increases expression ISO RGD:737501 6480464 Diethylhexyl Phthalate results in increased expression of PKM mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of PKM mRNA] CTD PMID:19850644 bisphenol A increases expression ISO RGD:737501 6480464 bisphenol A results in increased expression of PKM mRNA CTD PMID:19371625 , PMID:33670352 bisphenol A decreases expression ISO RGD:737501 6480464 bisphenol A results in decreased expression of PKM protein CTD PMID:34186270 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PKM protein CTD PMID:35999755 bisphenol A affects expression ISO RGD:737501 6480464 bisphenol A affects the expression of PKM mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO RGD:737501 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA CTD PMID:28628672 bisphenol A increases expression ISO RGD:3337 6480464 bisphenol A results in increased expression of PKM mRNA CTD PMID:12075121 , PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PKM mRNA CTD PMID:26063408 bisphenol A multiple interactions ISO RGD:3337 6480464 [Fructose co-treated with bisphenol A] results in decreased expression of PKM protein CTD PMID:26930160 Bisphenol B increases expression ISO RGD:737501 6480464 bisphenol B results in increased expression of PKM protein CTD PMID:34186270 bisphenol F multiple interactions ISO RGD:737501 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 bisphenol F increases expression ISO RGD:737501 6480464 bisphenol F results in increased expression of PKM protein CTD PMID:34186270 bisphenol F multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of PKM mRNA] more ... CTD PMID:34147605 bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of PKM mRNA, bisphenol F results in increased expression of PKM protein CTD PMID:34147605 C.I. Natural Red 20 multiple interactions EXP 6480464 shikonin inhibits the reaction [[Tobacco Smoke Pollution results in increased abundance of Particulate Matter] which results in increased expression of PKM protein] CTD PMID:35787437 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein CTD PMID:34481905 cadmium atom multiple interactions ISO RGD:737501 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:34481905 , PMID:36336208 cadmium dichloride multiple interactions ISO RGD:737501 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:24980261 more ... cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein CTD PMID:34481905 cadmium dichloride increases expression ISO RGD:3337 6480464 Cadmium Chloride results in increased expression of PKM mRNA CTD PMID:25993096 cadmium dichloride increases expression ISO RGD:737501 6480464 Cadmium Chloride results in increased expression of PKM protein CTD PMID:24527689 cadmium sulfate multiple interactions EXP 6480464 cadmium sulfate affects the reaction [MTF1 affects the expression of PKM mRNA] CTD PMID:16221973 caffeine increases phosphorylation ISO RGD:737501 6480464 Caffeine results in increased phosphorylation of PKM protein CTD PMID:35688186 carbon nanotube affects expression EXP 6480464 Nanotubes, Carbon affects the expression of PKM protein CTD PMID:21135415 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 CCCP multiple interactions ISO RGD:737501 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] CTD PMID:34481905 celastrol increases expression EXP 6480464 celastrol results in increased expression of PKM mRNA CTD PMID:35679966 celastrol multiple interactions EXP 6480464 [celastrol co-treated with Dietary Fats] results in increased expression of PKM mRNA CTD PMID:35679966 CGP 52608 multiple interactions ISO RGD:737501 6480464 CGP 52608 promotes the reaction [RORA protein binds to PKM gene] CTD PMID:28238834 chloromethylisothiazolinone increases metabolic processing ISO RGD:737501 6480464 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of PKM protein CTD PMID:29267982 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PKM mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PKM gene CTD PMID:20938992 cisplatin multiple interactions ISO RGD:737501 6480464 Cisplatin results in increased expression of and results in increased secretion of PKM protein CTD PMID:24980261 clobetasol increases expression EXP 6480464 Clobetasol results in increased expression of PKM mRNA CTD PMID:27462272 clozapine increases expression ISO RGD:3337 6480464 Clozapine results in increased expression of PKM mRNA CTD PMID:15860345 cobalt dichloride decreases expression ISO RGD:737501 6480464 cobaltous chloride results in decreased expression of PKM mRNA CTD PMID:19376846 cocaine affects expression ISO RGD:3337 6480464 Cocaine affects the expression of PKM mRNA CTD PMID:20187946 copper atom affects binding ISO RGD:737501 6480464 PKM protein binds to Copper CTD PMID:15359738 copper(0) affects binding ISO RGD:737501 6480464 PKM protein binds to Copper CTD PMID:15359738 coumarin affects phosphorylation ISO RGD:737501 6480464 coumarin affects the phosphorylation of PKM protein CTD PMID:35688186 coumestrol multiple interactions ISO RGD:737501 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PKM mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO RGD:737501 6480464 Asbestos, Crocidolite results in increased expression of PKM protein CTD PMID:29553831 cyclosporin A multiple interactions ISO RGD:737501 6480464 Cyclosporine results in increased expression of and results in increased secretion of PKM protein CTD PMID:24980261 cyclosporin A increases expression ISO RGD:737501 6480464 Cyclosporine results in increased expression of PKM mRNA CTD PMID:27989131 cyclosporin A decreases expression ISO RGD:737501 6480464 Cyclosporine results in decreased expression of PKM mRNA CTD PMID:21163907 more ... D-glucose increases uptake ISO RGD:737501 6480464 PKM protein results in increased uptake of Glucose CTD PMID:22574221 D-glucose multiple interactions ISO RGD:737501 6480464 Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]] more ... CTD PMID:23086999 more ... DDT multiple interactions ISO RGD:737501 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of and affects the localization of PKM protein alternative form] more ... CTD PMID:31724279 DDT increases expression ISO RGD:737501 6480464 DDT results in increased expression of PKM mRNA alternative form CTD PMID:31724279 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of PKM protein CTD PMID:33567340 dexamethasone multiple interactions ISO RGD:737501 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 diarsenic trioxide multiple interactions ISO RGD:737501 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PKM mRNA more ... CTD PMID:15894607 , PMID:31003765 diarsenic trioxide decreases expression ISO RGD:737501 6480464 Arsenic Trioxide results in decreased expression of PKM mRNA, Arsenic Trioxide results in decreased expression of PKM protein CTD PMID:31003765 diarsenic trioxide increases expression ISO RGD:737501 6480464 Arsenic Trioxide results in increased expression of PKM protein CTD PMID:25419056 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of PKM mRNA CTD PMID:21266533 dichloroacetic acid decreases expression ISO RGD:737501 6480464 Dichloroacetic Acid results in decreased expression of PKM protein CTD PMID:31654802 dicrotophos increases expression ISO RGD:737501 6480464 dicrotophos results in increased expression of PKM mRNA CTD PMID:28302478 dihydroartemisinin affects binding ISO RGD:737501 6480464 artenimol analog binds to PKM protein CTD PMID:26340163 dihydroartemisinin multiple interactions ISO RGD:737501 6480464 PKM protein inhibits the reaction [artenimol results in increased cleavage of CASP3 protein] more ... CTD PMID:34655567 diosmetin increases activity ISO RGD:737501 6480464 diosmetin results in increased activity of PKM protein CTD PMID:25388478 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of PKM mRNA CTD PMID:20880076 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PKM mRNA CTD PMID:30529165 dioxygen increases expression ISO RGD:737501 6480464 Oxygen deficiency results in increased expression of PKM protein CTD PMID:26087400 dioxygen multiple interactions ISO RGD:737501 6480464 [IL15 protein co-treated with Oxygen deficiency] results in increased expression of PKM mRNA CTD PMID:27129235 diuron increases expression ISO RGD:3337 6480464 Diuron results in increased expression of PKM mRNA CTD PMID:21551480 dopamine increases expression ISO RGD:737501 6480464 Dopamine results in increased expression of PKM protein CTD PMID:24675778 dorsomorphin multiple interactions ISO RGD:737501 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of PKM protein CTD PMID:21251210 doxorubicin decreases expression ISO RGD:737501 6480464 Doxorubicin results in decreased expression of PKM mRNA CTD PMID:29803840 doxorubicin multiple interactions EXP 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein] CTD PMID:21251210 elemental selenium increases expression ISO RGD:737501 6480464 Selenium results in increased expression of PKM mRNA CTD PMID:19244175 emodin affects localization ISO RGD:3337 6480464 Emodin affects the localization of PKM protein CTD PMID:34971761 emodin multiple interactions ISO RGD:3337 6480464 [[Emodin inhibits the reaction [PKM protein binds to PKM protein binds to PKM protein binds to PKM protein]] results in increased abundance of [PKM protein binds to PKM protein]] which binds to NFE2L2 protein more ... CTD PMID:34971761 emodin decreases activity ISO RGD:3337 6480464 Emodin results in decreased activity of PKM protein CTD PMID:34971761 endosulfan increases expression ISO RGD:3337 6480464 Endosulfan results in increased expression of PKM mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO RGD:737501 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PKM mRNA CTD PMID:19167446 enzyme inhibitor multiple interactions ISO RGD:737501 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PKM protein CTD PMID:23301498 ethanol affects splicing EXP 6480464 Ethanol affects the splicing of PKM mRNA CTD PMID:30319688 flavone multiple interactions ISO RGD:737501 6480464 flavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 flavonol multiple interactions ISO RGD:737501 6480464 3-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PKM mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PKM gene CTD PMID:20938992 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of PKM protein CTD PMID:33259821 formaldehyde increases expression ISO RGD:3337 6480464 Formaldehyde results in increased expression of PKM protein CTD PMID:33259821 fructose multiple interactions ISO RGD:3337 6480464 [Fructose co-treated with bisphenol A] results in decreased expression of PKM protein CTD PMID:26930160 fulvestrant multiple interactions ISO RGD:737501 6480464 Fulvestrant inhibits the reaction [3 more ... CTD PMID:28284859 , PMID:32078667 fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol F results in increased expression of PKM protein] CTD PMID:34147605 Fusaric acid multiple interactions ISO RGD:737501 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA] more ... CTD PMID:31654802 Fusaric acid increases expression ISO RGD:737501 6480464 Fusaric Acid results in increased expression of PKM mRNA, Fusaric Acid results in increased expression of PKM protein CTD PMID:31654802 galactose multiple interactions ISO RGD:737501 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA] CTD PMID:31654802 genistein increases expression ISO RGD:3337 6480464 Genistein results in increased expression of PKM mRNA CTD PMID:12075121 glucose increases uptake ISO RGD:737501 6480464 PKM protein results in increased uptake of Glucose CTD PMID:22574221 glucose multiple interactions ISO RGD:737501 6480464 Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]] more ... CTD PMID:23086999 more ... gold atom decreases expression EXP 6480464 Gold analog results in decreased expression of PKM protein CTD PMID:24780912 gold(0) decreases expression EXP 6480464 Gold analog results in decreased expression of PKM protein CTD PMID:24780912 GW 3965 multiple interactions EXP 6480464 GW 3965 inhibits the reaction [3 more ... CTD PMID:27052460 haloperidol increases expression ISO RGD:3337 6480464 Haloperidol results in increased expression of PKM mRNA CTD PMID:15860345 hydrogen peroxide decreases expression ISO RGD:3337 6480464 Hydrogen Peroxide results in decreased expression of PKM protein CTD PMID:23178681 hydrogen peroxide decreases expression ISO RGD:737501 6480464 Hydrogen Peroxide results in decreased expression of PKM protein CTD PMID:34581912 indometacin multiple interactions ISO RGD:737501 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 ivermectin affects expression ISO RGD:737501 6480464 Ivermectin affects the expression of PKM protein CTD PMID:32959892 L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of PKM mRNA CTD PMID:22139585 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PKM mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PKM gene CTD PMID:20938992 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of PKM mRNA CTD PMID:27339419 lovastatin decreases expression EXP 6480464 Lovastatin results in decreased expression of PKM mRNA CTD PMID:20493250 luteolin increases activity ISO RGD:737501 6480464 Luteolin results in increased activity of PKM protein CTD PMID:25388478 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of PKM mRNA], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of PKM protein] CTD PMID:34147605 mercury dichloride multiple interactions ISO RGD:737501 6480464 Mercuric Chloride results in increased expression of and results in increased secretion of PKM protein CTD PMID:24980261 methamphetamine increases expression ISO RGD:3337 6480464 Methamphetamine results in increased expression of PKM protein CTD PMID:19826936 methapyrilene decreases expression ISO RGD:3337 6480464 Methapyrilene results in decreased expression of PKM mRNA CTD PMID:28903497 methidathion increases expression EXP 6480464 methidathion results in increased expression of PKM mRNA CTD PMID:34813904 methylazoxymethanol increases expression EXP 6480464 methylazoxymethanol results in increased expression of PKM mRNA CTD PMID:17107856 methylmercury chloride increases expression ISO RGD:737501 6480464 methylmercuric chloride results in increased expression of PKM mRNA CTD PMID:28001369 miconazole increases expression EXP 6480464 Miconazole results in increased expression of PKM mRNA CTD PMID:27462272 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [quinone results in increased degradation of PKM protein] CTD PMID:25437431 N-acetyl-L-cysteine multiple interactions ISO RGD:737501 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:28284859 more ... N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PKM mRNA, 1-Methyl-4-phenylpyridinium results in decreased expression of PKM protein CTD PMID:17475336 , PMID:22776087 N-methyl-4-phenylpyridinium decreases expression ISO RGD:737501 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PKM protein CTD PMID:24675778 naphthalene multiple interactions EXP 6480464 [naphthalene co-treated with CFTR gene mutant form] results in decreased expression of PKM protein CTD PMID:19438287 nickel dichloride multiple interactions EXP 6480464 HIF1A affects the reaction [nickel chloride results in increased expression of PKM mRNA] CTD PMID:12426141 , PMID:12729255 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of PKM mRNA CTD PMID:12426141 more ... nickel subsulfide affects expression EXP 6480464 nickel subsulfide affects the expression of PKM mRNA CTD PMID:12729255 niclosamide increases expression ISO RGD:737501 6480464 Niclosamide results in increased expression of PKM mRNA CTD PMID:22576131 ochratoxin A multiple interactions ISO RGD:737501 6480464 ochratoxin A results in increased phosphorylation of and results in decreased activity of and affects the localization of PKM protein CTD PMID:32835834 ozone multiple interactions ISO RGD:737501 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PKM mRNA more ... CTD PMID:32699268 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PKM mRNA, [Air Pollutants results in increased abundance of Ozone] which results in increased expression of PKM mRNA CTD PMID:34911549 paclitaxel affects response to substance ISO RGD:737501 6480464 PKM protein affects the susceptibility to Paclitaxel CTD PMID:16217747 panobinostat increases expression ISO RGD:737501 6480464 panobinostat results in increased expression of PKM mRNA CTD PMID:26272509 panobinostat multiple interactions ISO RGD:737501 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of PKM mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:3337 6480464 Acetaminophen results in decreased expression of PKM mRNA CTD PMID:33387578 paraquat increases expression ISO RGD:3337 6480464 Paraquat results in increased expression of PKM mRNA CTD PMID:32680482 PCB138 decreases expression ISO RGD:3337 6480464 2 more ... CTD PMID:21673325 perfluorooctane-1-sulfonic acid increases expression ISO RGD:737501 6480464 perfluorooctane sulfonic acid results in increased expression of PKM mRNA CTD PMID:27153767 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PKM mRNA CTD PMID:36331819 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of PKM mRNA CTD PMID:19363144 phenylmercury acetate increases expression ISO RGD:737501 6480464 Phenylmercuric Acetate results in increased expression of PKM mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:737501 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 PhIP increases expression ISO RGD:3337 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of PKM mRNA CTD PMID:15215175 phosphoenolpyruvate increases metabolic processing ISO RGD:737501 6480464 PKM protein results in increased metabolism of Phosphoenolpyruvate CTD PMID:25388478 phosphoenolpyruvate multiple interactions ISO RGD:737501 6480464 3-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] more ... CTD PMID:25388478 potassium dichromate increases expression ISO RGD:737501 6480464 Potassium Dichromate results in increased expression of PKM protein CTD PMID:20332019 more ... potassium dichromate multiple interactions ISO RGD:737501 6480464 3-methyladenine inhibits the reaction [Potassium Dichromate results in increased expression of PKM protein] more ... CTD PMID:32569804 , PMID:36473502 progesterone affects expression EXP 6480464 Progesterone affects the expression of PKM mRNA CTD PMID:17251523 promethazine decreases expression ISO RGD:3337 6480464 Promethazine results in decreased expression of PKM mRNA CTD PMID:28903497 Propiverine affects binding ISO RGD:3337 6480464 propiverine binds to PKM protein CTD PMID:29273565 quartz affects expression ISO RGD:737501 6480464 Quartz affects the expression of PKM protein CTD PMID:27917503 quercetin decreases expression ISO RGD:737501 6480464 Quercetin results in decreased expression of PKM protein CTD PMID:15221776 , PMID:35945655 quercetin multiple interactions ISO RGD:737501 6480464 G3BP1 protein inhibits the reaction [Quercetin results in decreased expression of PKM protein] CTD PMID:35945655 quercetin increases expression ISO RGD:737501 6480464 Quercetin results in increased expression of PKM mRNA, Quercetin results in increased expression of PKM protein CTD PMID:14750173 , PMID:21632981 rac-lactic acid increases abundance ISO RGD:737501 6480464 PKM protein results in increased abundance of Lactic Acid CTD PMID:22574221 rac-lactic acid increases expression ISO RGD:737501 6480464 Lactic Acid results in increased expression of PKM protein CTD PMID:36336208 rac-lactic acid multiple interactions ISO RGD:737501 6480464 Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:36336208 reactive oxygen species multiple interactions EXP 6480464 Reactive Oxygen Species affects the reaction [quinone results in increased degradation of PKM protein] CTD PMID:25437431 resveratrol multiple interactions ISO RGD:737501 6480464 [resveratrol results in decreased activity of MTOR protein] which results in decreased expression of PKM mRNA, [resveratrol results in decreased activity of MTOR protein] which results in decreased expression of PKM protein CTD PMID:22574221 resveratrol increases expression ISO RGD:3337 6480464 resveratrol results in increased expression of PKM mRNA CTD PMID:25905778 resveratrol decreases response to substance ISO RGD:737501 6480464 PKM protein results in decreased susceptibility to resveratrol CTD PMID:22574221 rotenone increases oxidation ISO RGD:3337 6480464 Rotenone results in increased oxidation of PKM protein CTD PMID:30951809 SAICAR multiple interactions ISO RGD:737501 6480464 Glucose deficiency promotes the reaction [SAICAR binds to and results in increased activity of PKM protein] CTD PMID:23086999 SB 431542 multiple interactions ISO RGD:737501 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 scutellarin increases activity ISO RGD:737501 6480464 scutellarin results in increased activity of PKM protein CTD PMID:25388478 selenium atom increases expression ISO RGD:737501 6480464 Selenium results in increased expression of PKM mRNA CTD PMID:19244175 Shikonin multiple interactions EXP 6480464 shikonin inhibits the reaction [[Tobacco Smoke Pollution results in increased abundance of Particulate Matter] which results in increased expression of PKM protein] CTD PMID:35787437 silicon dioxide increases secretion ISO RGD:737501 6480464 Silicon Dioxide analog results in increased secretion of PKM protein CTD PMID:25895662 silicon dioxide affects expression ISO RGD:737501 6480464 Silicon Dioxide affects the expression of PKM protein CTD PMID:27917503 sirolimus multiple interactions ISO RGD:737501 6480464 [Sirolimus results in decreased activity of MTOR protein] which results in decreased expression of PKM protein, Sirolimus inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] CTD PMID:22574221 , PMID:36336208 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of PKM mRNA CTD PMID:17450228 sodium arsenite affects expression ISO RGD:737501 6480464 sodium arsenite affects the expression of PKM mRNA CTD PMID:34032870 sodium arsenite decreases expression ISO RGD:3337 6480464 sodium arsenite results in decreased expression of PKM mRNA, sodium arsenite results in decreased expression of PKM protein CTD PMID:29459688 , PMID:35314868 sodium arsenite increases expression ISO RGD:737501 6480464 sodium arsenite results in increased expression of PKM mRNA CTD PMID:28595984 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of PKM protein CTD PMID:27548804 sodium nitrate multiple interactions EXP 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein] CTD PMID:21251210 streptozocin affects expression EXP 6480464 Streptozocin affects the expression of PKM mRNA CTD PMID:18583417 sulindac sulfide decreases expression ISO RGD:737501 6480464 sulindac sulfide results in decreased expression of PKM mRNA CTD PMID:16184548 sunitinib increases expression ISO RGD:737501 6480464 Sunitinib results in increased expression of PKM mRNA CTD PMID:31533062 T-2 toxin affects expression ISO RGD:3337 6480464 T-2 Toxin affects the expression of PKM protein CTD PMID:26141394 tanespimycin decreases expression ISO RGD:737501 6480464 tanespimycin results in decreased expression of PKM protein CTD PMID:31370342 tangeretin increases activity ISO RGD:737501 6480464 tangeretin results in increased activity of PKM protein CTD PMID:25388478 temozolomide decreases expression ISO RGD:737501 6480464 Temozolomide results in decreased expression of PKM mRNA CTD PMID:31758290 tetrachloromethane increases expression ISO RGD:3337 6480464 Carbon Tetrachloride results in increased expression of PKM protein CTD PMID:12629582 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PKM mRNA CTD PMID:27339419 , PMID:31919559 thapsigargin decreases expression ISO RGD:737501 6480464 Thapsigargin results in decreased expression of PKM mRNA CTD PMID:22378314 thapsigargin increases expression ISO RGD:3337 6480464 Thapsigargin results in increased expression of PKM protein CTD PMID:35544339 thioacetamide increases expression ISO RGD:3337 6480464 Thioacetamide results in increased expression of PKM mRNA CTD PMID:28903497 , PMID:34492290 tributylstannane decreases expression ISO RGD:737501 6480464 tributyltin analog results in decreased expression of PKM protein CTD PMID:31634547 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of PKM mRNA CTD PMID:31939706 trichloroethene affects expression EXP 6480464 Trichloroethylene affects the expression of PKM mRNA CTD PMID:21135412 trichostatin A increases expression ISO RGD:737501 6480464 trichostatin A results in increased expression of PKM mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:737501 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 triclosan decreases expression ISO RGD:737501 6480464 Triclosan results in decreased expression of PKM mRNA CTD PMID:30510588 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of PKM mRNA CTD PMID:19042947 triphenylstannane decreases expression ISO RGD:737501 6480464 triphenyltin analog results in decreased expression of PKM protein CTD PMID:31634547 Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of PKM mRNA CTD PMID:34087332 tunicamycin decreases expression ISO RGD:737501 6480464 Tunicamycin results in decreased expression of PKM mRNA CTD PMID:22378314 tunicamycin increases expression ISO RGD:737501 6480464 Tunicamycin results in increased expression of PKM protein CTD PMID:36473502 undecane decreases expression ISO RGD:3337 6480464 undecane results in decreased expression of PKM protein CTD PMID:17337753 valproic acid increases expression ISO RGD:737501 6480464 Valproic Acid results in increased expression of PKM mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO RGD:737501 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 vitamin E increases expression ISO RGD:737501 6480464 Vitamin E results in increased expression of PKM mRNA CTD PMID:19244175 vorinostat increases expression ISO RGD:737501 6480464 vorinostat results in increased expression of PKM mRNA CTD PMID:26272509 vorinostat multiple interactions ISO RGD:737501 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 warfarin decreases expression EXP 6480464 Warfarin results in decreased expression of PKM mRNA CTD PMID:20493250 wogonin multiple interactions ISO RGD:737501 6480464 wogonin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 Yessotoxin increases expression ISO RGD:737501 6480464 yessotoxin analog results in increased expression of PKM mRNA CTD PMID:30679557 zinc atom decreases expression ISO RGD:737501 6480464 Zinc results in decreased expression of PKM protein CTD PMID:15984569 zinc(0) decreases expression ISO RGD:737501 6480464 Zinc results in decreased expression of PKM protein CTD PMID:15984569