Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ccl5 (chemokine (C-C motif) ligand 5) Mus musculus
Analyze
Symbol: Ccl5
Name: chemokine (C-C motif) ligand 5
Description: Exhibits CCR1 chemokine receptor binding activity. Involved in several processes, including negative regulation of macrophage apoptotic process; positive regulation of monocyte chemotaxis; and response to tumor necrosis factor. Localizes to the cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in asthma; hepatitis C; pancreatitis; pulmonary tuberculosis; and type 1 diabetes mellitus. Is expressed in several structures, including central nervous system; gonad; hemolymphoid system; late tubule; and retina. Orthologous to human CCL5 (C-C motif chemokine ligand 5); PARTICIPATES IN syndecan signaling pathway; Chagas disease pathway; influenza A pathway; INTERACTS WITH (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid; 1-chloro-2,4-dinitrobenzene; 1-fluoro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-C motif chemokine 5; MuRantes; RANTES; Scya5; SIS-delta; SISd; small inducible cytokine A5; small-inducible cytokine A5; T-cell-specific protein RANTES; TCP228
Orthologs:
Homo sapiens (human) : CCL5 (C-C motif chemokine ligand 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccl5 (C-C motif chemokine ligand 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccl5 (C-C motif chemokine ligand 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CCL5 (C-C motif chemokine ligand 5)
Canis lupus familiaris (dog) : CCL5 (C-C motif chemokine ligand 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccl5 (C-C motif chemokine ligand 5)
Sus scrofa (pig) : CCL5 (C-C motif chemokine ligand 5)
Chlorocebus sabaeus (African green monkey) : CCL5 (C-C motif chemokine ligand 5)
Heterocephalus glaber (naked mole-rat) : Ccl5 (C-C motif chemokine ligand 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1183,525,778 - 83,530,518 (-)Ensembl
GRCm381183,525,778 - 83,530,518 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371183,339,280 - 83,344,020 (-)NCBIGRCm37mm9NCBIm37
MGSCv361183,341,974 - 83,346,692 (-)NCBImm8
Celera1193,127,305 - 93,132,049 (-)NCBICelera
Cytogenetic Map11 CNCBI
cM Map1150.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ccl5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69127
Created: 2001-11-08
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.