Gab1 (growth factor receptor bound protein 2-associated protein 1) - Rat Genome Database
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Gene: Gab1 (growth factor receptor bound protein 2-associated protein 1) Mus musculus
Analyze
Symbol: Gab1
Name: growth factor receptor bound protein 2-associated protein 1
RGD ID: 1322355
MGI Page MGI
Description: Involved in several processes, including activation of JUN kinase activity; cell surface receptor signaling pathway; and labyrinthine layer development. Localizes to cytoplasm. Is expressed in several structures, including brain; genitourinary system; heart; liver; and lung. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 26. Orthologous to human GAB1 (GRB2 associated binding protein 1); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; erythropoietin signaling pathway; fibroblast growth factor signaling pathway; INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408973; AW107238; GRB2-associated binder 1; GRB2-associated-binding protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39881,491,060 - 81,607,148 (-)NCBIGRCm39mm39
GRCm38880,764,431 - 80,880,519 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl880,764,438 - 80,880,519 (-)EnsemblGRCm38mm10GRCm38
MGSCv37883,288,333 - 83,404,378 (-)NCBIGRCm37mm9NCBIm37
MGSCv36883,660,180 - 83,776,225 (-)NCBImm8
Celera885,038,223 - 85,155,227 (-)NCBICelera
Cytogenetic Map8C2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal behavior  (IAGP)
abnormal cardiac muscle relaxation  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cell migration  (IAGP)
abnormal diaphragm development  (IAGP)
abnormal endocardium morphology  (IAGP)
abnormal epidermis stratum granulosum morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal hair follicle development  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal intrinsic tongue muscle morphology  (IAGP)
abnormal keratinocyte physiology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal muscle precursor cell migration  (IAGP)
abnormal muscle precursor cell morphology  (IAGP)
abnormal myogenesis  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placenta vasculature  (IAGP)
abnormal skeletal muscle morphology  (IAGP)
absent eyelids  (IAGP)
cleft secondary palate  (IAGP)
congestive heart failure  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased embryo size  (IAGP)
decreased glycogen level  (IAGP)
decreased liver weight  (IAGP)
decreased skeletal muscle mass  (IAGP)
decreased tongue size  (IAGP)
decreased trophoblast giant cell number  (IAGP)
dilated heart  (IAGP)
dilated heart left ventricle  (IAGP)
dilated heart right ventricle  (IAGP)
disorganized placental labyrinth  (IAGP)
early eyelid opening  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
eyelids open at birth  (IAGP)
fetal growth retardation  (IAGP)
hemopericardium  (IAGP)
hemorrhage  (IAGP)
hypaxial muscle hypoplasia  (IAGP)
impaired wound healing  (IAGP)
improved glucose tolerance  (IAGP)
increased heart weight  (IAGP)
increased insulin sensitivity  (IAGP)
increased left ventricle diastolic pressure  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality, incomplete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
palatal shelves fail to meet at midline  (IAGP)
petechiae  (IAGP)
placental labyrinth hypoplasia  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
small placenta  (IAGP)
thin epidermis  (IAGP)
thin interventricular septum  (IAGP)
thin placenta labyrinth  (IAGP)
thin ventricular wall  (IAGP)
ventricular hypoplasia  (IAGP)
References

Additional References at PubMed
PMID:8906793   PMID:9299490   PMID:10349636   PMID:10779359   PMID:10871282   PMID:10922068   PMID:10995442   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11445578   PMID:11707404  
PMID:11896055   PMID:11940581   PMID:11994464   PMID:12058075   PMID:12095915   PMID:12176364   PMID:12477932   PMID:12520002   PMID:12808090   PMID:12819203   PMID:12904583   PMID:14610273  
PMID:14668796   PMID:14749370   PMID:14973141   PMID:15102471   PMID:15199124   PMID:15273746   PMID:15314156   PMID:15351743   PMID:15489334   PMID:15736129   PMID:15821749   PMID:16141072  
PMID:16141073   PMID:16166380   PMID:16284184   PMID:16738330   PMID:16775003   PMID:17178724   PMID:17332510   PMID:17571162   PMID:17881575   PMID:17923692   PMID:18799693   PMID:19233262  
PMID:19401591   PMID:19521500   PMID:20124419   PMID:20332103   PMID:20435932   PMID:20506405   PMID:20723025   PMID:21282639   PMID:21293003   PMID:21372298   PMID:21677750   PMID:21862448  
PMID:22664868   PMID:22883624   PMID:23424281   PMID:23452850   PMID:23612964   PMID:24284065   PMID:24872569   PMID:24951957   PMID:25159185   PMID:25501549   PMID:25825741   PMID:26393505  
PMID:26456821   PMID:26517531   PMID:26728565   PMID:27793798   PMID:27811945   PMID:27861634   PMID:28542067   PMID:28591834   PMID:28687632   PMID:28722233   PMID:29386106   PMID:29408807  
PMID:30154213   PMID:30718289   PMID:31505074   PMID:31651330   PMID:31892308   PMID:31944179   PMID:32325033   PMID:32358519  


Genomics

Comparative Map Data
Gab1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39881,491,060 - 81,607,148 (-)NCBIGRCm39mm39
GRCm38880,764,431 - 80,880,519 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl880,764,438 - 80,880,519 (-)EnsemblGRCm38mm10GRCm38
MGSCv37883,288,333 - 83,404,378 (-)NCBIGRCm37mm9NCBIm37
MGSCv36883,660,180 - 83,776,225 (-)NCBImm8
Celera885,038,223 - 85,155,227 (-)NCBICelera
Cytogenetic Map8C2NCBI
GAB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4143,336,762 - 143,474,568 (+)EnsemblGRCh38hg38GRCh38
GRCh384143,336,876 - 143,474,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374144,257,680 - 144,395,718 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364144,477,500 - 144,610,729 (+)NCBINCBI36hg18NCBI36
Celera4141,587,895 - 141,725,726 (+)NCBI
Cytogenetic Map4q31.21NCBI
HuRef4139,987,709 - 140,125,505 (+)NCBIHuRef
CHM1_14144,235,244 - 144,372,935 (+)NCBICHM1_1
Gab1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01930,794,290 - 30,903,819 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1930,794,571 - 30,902,008 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01941,699,636 - 41,808,268 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41928,980,284 - 29,088,877 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11928,977,650 - 29,091,892 (+)NCBI
Celera1926,648,689 - 26,756,049 (+)NCBICelera
Cytogenetic Map19q11NCBI
Gab1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547161,120 - 191,175 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547161,580 - 191,175 (-)NCBIChiLan1.0ChiLan1.0
GAB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14146,996,936 - 147,134,576 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4146,996,936 - 147,133,672 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04135,697,939 - 135,834,755 (+)NCBIMhudiblu_PPA_v0panPan3
GAB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1912,616 - 156,694 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11910,269 - 117,808 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gab1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365354,934,743 - 5,048,698 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl884,257,958 - 84,391,621 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1884,257,958 - 84,391,511 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2889,408,945 - 89,540,504 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GAB1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1790,197,374 - 90,323,024 (+)NCBI
ChlSab1.1 Ensembl790,197,620 - 90,322,077 (+)Ensembl
Gab1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248532,639,882 - 2,763,195 (+)NCBI

Position Markers
RH124801  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38880,764,574 - 80,764,671UniSTSGRCm38
MGSCv37883,288,473 - 83,288,570UniSTSGRCm37
Celera885,038,363 - 85,038,460UniSTS
Cytogenetic Map8C3UniSTS
UniSTS:235942  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38880,845,274 - 80,845,542UniSTSGRCm38
MGSCv37883,369,173 - 83,369,441UniSTSGRCm37
Celera885,119,092 - 85,119,360UniSTS
Cytogenetic Map8C3UniSTS
AW107238  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38880,764,646 - 80,764,771UniSTSGRCm38
MGSCv37883,288,545 - 83,288,670UniSTSGRCm37
Celera885,038,435 - 85,038,560UniSTS
Cytogenetic Map8C3UniSTS
Whitehead/MRC_RH8866.23UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88006677589014359Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:731
Count of miRNA genes:441
Interacting mature miRNAs:546
Transcripts:ENSMUST00000034150
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001301298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ250669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX523462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000034150   ⟹   ENSMUSP00000034150
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl880,764,440 - 80,880,496 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210676   ⟹   ENSMUSP00000147784
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl880,764,438 - 80,880,519 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211018
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl880,791,562 - 80,830,884 (-)Ensembl
RefSeq Acc Id: NM_001301298   ⟹   NP_001288227
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,060 - 81,607,148 (-)NCBI
GRCm38880,764,431 - 80,880,519 (-)NCBI
Celera885,038,220 - 85,155,267 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021356   ⟹   NP_067331
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,063 - 81,607,108 (-)NCBI
GRCm38880,764,434 - 80,880,479 (-)NCBI
MGSCv37883,288,333 - 83,404,378 (-)RGD
Celera885,038,220 - 85,155,267 (-)NCBI
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530676   ⟹   XP_006530739
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,060 - 81,595,795 (-)NCBI
GRCm38880,764,431 - 80,869,169 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006530677   ⟹   XP_006530740
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,060 - 81,606,521 (-)NCBI
GRCm38880,764,431 - 80,879,892 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011248309   ⟹   XP_011246611
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,060 - 81,586,641 (-)NCBI
GRCm38880,764,431 - 80,860,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011248310   ⟹   XP_011246612
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,060 - 81,585,316 (-)NCBI
GRCm38880,764,431 - 80,858,702 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312576   ⟹   XP_017168065
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,060 - 81,595,193 (-)NCBI
GRCm38880,764,431 - 80,868,599 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243298   ⟹   XP_030099158
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,067 - 81,607,118 (-)NCBI
GRCm38880,764,438 - 80,880,496 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036153759   ⟹   XP_036009652
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,060 - 81,606,254 (-)NCBI
RefSeq Acc Id: XM_036153760   ⟹   XP_036009653
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,491,067 - 81,606,254 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_067331   ⟸   NM_021356
- Peptide Label: isoform 2
- UniProtKB: Q9QYY0 (UniProtKB/Swiss-Prot),   Q505A4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530740   ⟸   XM_006530677
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006530739   ⟸   XM_006530676
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001288227   ⟸   NM_001301298
- Peptide Label: isoform 1
- UniProtKB: A0A1B0GS41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246611   ⟸   XM_011248309
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011246612   ⟸   XM_011248310
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017168065   ⟸   XM_017312576
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030099158   ⟸   XM_030243298
- Peptide Label: isoform X4
RefSeq Acc Id: ENSMUSP00000034150   ⟸   ENSMUST00000034150
RefSeq Acc Id: ENSMUSP00000147784   ⟸   ENSMUST00000210676
RefSeq Acc Id: XP_036009652   ⟸   XM_036153759
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036009653   ⟸   XM_036153760
- Peptide Label: isoform X3
Protein Domains
PH

Promoters
RGD ID:8667567
Promoter ID:EPDNEW_M11815
Type:multiple initiation site
Name:Gab1_2
Description:Mus musculus growth factor receptor bound protein 2-associatedprotein 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11816  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38880,879,772 - 80,879,832EPDNEW
RGD ID:8667569
Promoter ID:EPDNEW_M11816
Type:initiation region
Name:Gab1_1
Description:Mus musculus growth factor receptor bound protein 2-associatedprotein 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11815  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38880,880,488 - 80,880,548EPDNEW
RGD ID:6843174
Promoter ID:MM_KWN:54967
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000034150,   UC009MJC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36883,403,446 - 83,404,777 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108088 AgrOrtholog
Ensembl Genes ENSMUSG00000031714 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000034150 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000147784 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034150 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000210676 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14388 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:108088 ENTREZGENE
NCBI Gene 14388 ENTREZGENE
Pfam PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GAB1 RGD
PhenoGen Gab1 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.277409 ENTREZGENE
UniProt A0A1B0GS41 ENTREZGENE, UniProtKB/TrEMBL
  GAB1_MOUSE UniProtKB/Swiss-Prot
  Q505A4 ENTREZGENE, UniProtKB/TrEMBL
  Q9QYY0 ENTREZGENE
UniProt Secondary Q91VW7 UniProtKB/Swiss-Prot