Cdkn1a (cyclin dependent kinase inhibitor 1A) - Rat Genome Database

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Gene: Cdkn1a (cyclin dependent kinase inhibitor 1A) Mus musculus
Symbol: Cdkn1a
Name: cyclin dependent kinase inhibitor 1A (Ensembl:cyclin dependent kinase inhibitor 1A (P21))
RGD ID: 732911
Description: Enables cyclin binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in several processes, including cellular response to UV-B; cellular response to amino acid starvation; and negative regulation of cardiac muscle tissue regeneration. Acts upstream of or within several processes, including cellular response to gamma radiation; regulation of macromolecule biosynthetic process; and signal transduction by p53 class mediator. Located in cytosol. Part of cyclin-dependent protein kinase holoenzyme complex. Is active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study hepatocellular carcinoma; systemic lupus erythematosus; and urinary bladder cancer. Human ortholog(s) of this gene implicated in high grade glioma; ocular hypertension; oral mucosa leukoplakia; oral squamous cell carcinoma; and primary open angle glaucoma. Orthologous to human CDKN1A (cyclin dependent kinase inhibitor 1A).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CAP; CAP20; CDK; CDK-interacting protein 1; CDKI; Cdkn; Cdkn1; CI; CIP1; cyclin dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; mda; mda6; melanoma differentiation-associated protein; P2; P21; p21; p21C; p21Cip1; p21W; p21WAF; SD; SDI1; Waf; Waf1
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391729,309,953 - 29,319,696 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1729,309,950 - 29,319,701 (+)EnsemblGRCm39 Ensembl
GRCm381729,090,979 - 29,100,722 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,090,976 - 29,100,727 (+)EnsemblGRCm38mm10GRCm38
MGSCv371729,227,931 - 29,237,667 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361728,821,439 - 28,828,386 (+)NCBIMGSCv36mm8
Celera1729,647,617 - 29,657,304 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)