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Gene: Cdkn1a (cyclin-dependent kinase inhibitor 1A (P21)) Mus musculus
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Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A (P21)
Description: Exhibits cyclin binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in several processes, including cellular response to radiation; negative regulation of cell cycle; and signal transduction by p53 class mediator. Localizes to the cyclin-dependent protein kinase holoenzyme complex; cytosol; and nucleus. Used to study hepatocellular carcinoma and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in malignant glioma; ocular hypertension; oral mucosa leukoplakia; oral squamous cell carcinoma; and primary open angle glaucoma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human CDKN1A (cyclin dependent kinase inhibitor 1A).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAP20; CDK-interacting protein 1; CDKI; Cdkn1; CIP1; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; mda6; melanoma differentiation-associated protein; P21; p21; p21Cip1; p21WAF; SDI1; Waf1
Orthologs:
Homo sapiens (human) : CDKN1A (cyclin dependent kinase inhibitor 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdkn1a (cyclin-dependent kinase inhibitor 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdkn1a (cyclin dependent kinase inhibitor 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : CDKN1A (cyclin dependent kinase inhibitor 1A)
Canis lupus familiaris (dog) : CDKN1A (cyclin dependent kinase inhibitor 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdkn1a (cyclin dependent kinase inhibitor 1A)
Sus scrofa (pig) : CDKN1A (cyclin dependent kinase inhibitor 1A)
Chlorocebus sabaeus (green monkey) : CDKN1A (cyclin dependent kinase inhibitor 1A)
Heterocephalus glaber (naked mole-rat) : Cdkn1a (cyclin dependent kinase inhibitor 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1729,090,976 - 29,100,727 (+)Ensembl
GRCm381729,090,979 - 29,100,722 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371729,227,931 - 29,237,667 (+)NCBIGRCm37mm9NCBIm37
MGSCv361728,821,439 - 28,828,386 (+)NCBImm8
Celera1729,647,617 - 29,657,304 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model