Fbxo21 (F-box protein 21) - Rat Genome Database

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Gene: Fbxo21 (F-box protein 21) Mus musculus
Analyze
Symbol: Fbxo21
Name: F-box protein 21
RGD ID: 1316491
MGI Page MGI
Description: Predicted to enable DNA binding activity. Is expressed in nervous system and neural retina. Orthologous to human FBXO21 (F-box protein 21).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810425J22Rik; AU016673; F-box only protein 21; MGC28066; mKIAA0875
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm5403  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395118,114,835 - 118,148,263 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5118,114,795 - 118,148,266 (+)EnsemblGRCm39 Ensembl
GRCm385117,976,770 - 118,010,198 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5117,976,730 - 118,010,201 (+)EnsemblGRCm38mm10GRCm38
MGSCv375118,426,779 - 118,460,200 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365118,237,800 - 118,271,221 (+)NCBIMGSCv36mm8
Celera5115,069,722 - 115,105,195 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map557.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
aflatoxin B1  (ISO)
amitrole  (ISO)
amphetamine  (ISO)
arsenite(3-)  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
fenofibrate  (EXP)
flutamide  (ISO)
furan  (EXP)
gentamycin  (ISO)
inulin  (EXP)
ivermectin  (ISO)
ketoconazole  (ISO)
leflunomide  (ISO)
menadione  (ISO)
nefazodone  (ISO)
paracetamol  (EXP)
parathion  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
rotenone  (ISO)
senecionine  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
tamoxifen  (EXP)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Systematic analysis and nomenclature of mammalian F-box proteins. Jin J, etal., Genes Dev 2004 Nov 1;18(21):2573-80.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12465718   PMID:12477932   PMID:12520002   PMID:15489334   PMID:15747579   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:21267068   PMID:26496610   PMID:27063938   PMID:27325702   PMID:32325033   PMID:34321999   PMID:35987460   PMID:38355793  


Genomics

Comparative Map Data
Fbxo21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395118,114,835 - 118,148,263 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5118,114,795 - 118,148,266 (+)EnsemblGRCm39 Ensembl
GRCm385117,976,770 - 118,010,198 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5117,976,730 - 118,010,201 (+)EnsemblGRCm38mm10GRCm38
MGSCv375118,426,779 - 118,460,200 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365118,237,800 - 118,271,221 (+)NCBIMGSCv36mm8
Celera5115,069,722 - 115,105,195 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map557.73NCBI
FBXO21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812117,141,991 - 117,190,470 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12117,141,991 - 117,190,470 (-)EnsemblGRCh38hg38GRCh38
GRCh3712117,579,796 - 117,628,275 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612116,065,968 - 116,112,683 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412116,044,305 - 116,091,020NCBI
Celera12117,211,091 - 117,257,810 (-)NCBICelera
Cytogenetic Map12q24.22NCBI
HuRef12114,590,452 - 114,637,170 (-)NCBIHuRef
CHM1_112117,549,459 - 117,596,178 (-)NCBICHM1_1
T2T-CHM13v2.012117,123,006 - 117,171,512 (-)NCBIT2T-CHM13v2.0
Fbxo21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81244,231,918 - 44,266,035 (-)NCBIGRCr8
mRatBN7.21238,570,878 - 38,605,133 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1238,571,023 - 38,605,133 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1239,746,358 - 39,780,475 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01240,360,153 - 40,394,270 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01239,413,118 - 39,447,235 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01244,244,633 - 44,279,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1244,246,508 - 44,279,002 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01246,075,020 - 46,109,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,719,654 - 39,753,892 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11239,585,071 - 39,617,279 (-)NCBI
Celera1240,229,218 - 40,263,586 (-)NCBICelera
Cytogenetic Map12q16NCBI
Fbxo21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545513,988,338 - 14,030,589 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545513,989,149 - 14,028,309 (+)NCBIChiLan1.0ChiLan1.0
FBXO21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210125,204,573 - 125,252,420 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112125,200,955 - 125,248,454 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012114,718,678 - 114,766,573 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112118,095,827 - 118,142,658 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12118,095,827 - 118,142,658 (-)Ensemblpanpan1.1panPan2
FBXO21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12613,722,301 - 13,769,273 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2613,725,137 - 13,769,234 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2613,716,520 - 13,763,485 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02613,982,350 - 14,029,188 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2613,982,352 - 14,029,175 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12613,944,034 - 13,991,442 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02614,021,247 - 14,068,787 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02614,056,805 - 14,104,346 (-)NCBIUU_Cfam_GSD_1.0
Fbxo21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118154,123,813 - 154,163,644 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365585,316,330 - 5,356,689 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365585,316,306 - 5,355,442 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1435,313,629 - 35,356,842 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11435,313,608 - 35,354,859 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21437,533,296 - 37,574,536 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111112,456,262 - 112,504,730 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11112,456,191 - 112,504,703 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037132,576,709 - 132,626,041 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474716,130,125 - 16,168,030 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474716,130,099 - 16,167,869 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:769
Count of miRNA genes:479
Interacting mature miRNAs:566
Transcripts:ENSMUST00000035579
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5114021753129632606Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108762509126882944Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse

Markers in Region
AW558874  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385118,009,596 - 118,009,737UniSTSGRCm38
MGSCv375118,459,605 - 118,459,746UniSTSGRCm37
Celera5115,104,600 - 115,104,741UniSTS
Cytogenetic Map5FUniSTS
Whitehead/MRC_RH51434.19UniSTS
UniSTS:235286  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385118,008,237 - 118,008,503UniSTSGRCm38
MGSCv375118,458,246 - 118,458,512UniSTSGRCm37
Celera5115,103,241 - 115,103,507UniSTS
Cytogenetic Map5FUniSTS
UniSTS:235290  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385118,009,650 - 118,009,744UniSTSGRCm38
MGSCv375118,459,659 - 118,459,753UniSTSGRCm37
Celera5115,104,654 - 115,104,748UniSTS
Cytogenetic Map5FUniSTS
UniSTS:238074  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X128,060,794 - 128,061,038UniSTSGRCm38
GRCm385117,988,789 - 117,989,232UniSTSGRCm38
MGSCv375118,438,798 - 118,439,241UniSTSGRCm37
MGSCv37X124,595,330 - 124,595,574UniSTSGRCm37
Celera5115,081,752 - 115,082,195UniSTS
CeleraX110,977,041 - 110,977,285UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map5FUniSTS
D5Abb2e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385118,008,129 - 118,008,281UniSTSGRCm38
MGSCv375118,458,138 - 118,458,290UniSTSGRCm37
Celera5115,103,127 - 115,103,285UniSTS
Cytogenetic Map5FUniSTS
cM Map566.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001346588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB093270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC114993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE954194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP754360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY478760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000035579   ⟹   ENSMUSP00000035506
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,114,849 - 118,148,265 (+)Ensembl
GRCm38.p6 Ensembl5117,976,784 - 118,010,200 (+)Ensembl
Ensembl Acc Id: ENSMUST00000200780
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,115,379 - 118,124,285 (+)Ensembl
GRCm38.p6 Ensembl5117,977,314 - 117,986,220 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,114,839 - 118,125,637 (+)Ensembl
GRCm38.p6 Ensembl5117,976,774 - 117,987,572 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201611   ⟹   ENSMUSP00000144071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,115,036 - 118,146,627 (+)Ensembl
GRCm38.p6 Ensembl5117,976,971 - 118,008,562 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201889
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,117,389 - 118,124,171 (+)Ensembl
GRCm38.p6 Ensembl5117,979,324 - 117,986,106 (+)Ensembl
Ensembl Acc Id: ENSMUST00000202447   ⟹   ENSMUSP00000143873
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5118,114,795 - 118,148,266 (+)Ensembl
GRCm38.p6 Ensembl5117,976,730 - 118,010,201 (+)Ensembl
RefSeq Acc Id: NM_001346588   ⟹   NP_001333517
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395118,114,835 - 118,148,263 (+)NCBI
GRCm385117,976,770 - 118,010,198 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145564   ⟹   NP_663539
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395118,114,835 - 118,148,263 (+)NCBI
GRCm385117,976,770 - 118,010,198 (+)NCBI
MGSCv375118,426,779 - 118,460,200 (+)RGD
Celera5115,069,722 - 115,105,195 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_663539   ⟸   NM_145564
- Peptide Label: isoform 1
- UniProtKB: Q8VDH1 (UniProtKB/Swiss-Prot),   Q8CHC6 (UniProtKB/Swiss-Prot),   Q8BHA5 (UniProtKB/Swiss-Prot),   A0A0J9YU92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001333517   ⟸   NM_001346588
- Peptide Label: isoform 2
- UniProtKB: A0A0J9YU92 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000143873   ⟸   ENSMUST00000202447
Ensembl Acc Id: ENSMUSP00000035506   ⟸   ENSMUST00000035579
Ensembl Acc Id: ENSMUSP00000144071   ⟸   ENSMUST00000201611
Protein Domains
F-box   Hemimethylated DNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VDH1-F1-model_v2 AlphaFold Q8VDH1 1-627 view protein structure

Promoters
RGD ID:6887822
Promoter ID:EPDNEW_M7362
Type:initiation region
Name:Fbxo21_1
Description:Mus musculus F-box protein 21 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385117,976,770 - 117,976,830EPDNEW
RGD ID:6837508
Promoter ID:MM_KWN:43769
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B6,   Spleen
Transcripts:NM_145564,   UC008ZFZ.1,   UC008ZGB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365118,426,619 - 118,427,119 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924223 AgrOrtholog
Ensembl Genes ENSMUSG00000032898 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000035579 ENTREZGENE
  ENSMUST00000035579.10 UniProtKB/Swiss-Prot
  ENSMUST00000201611.2 UniProtKB/TrEMBL
  ENSMUST00000202447 ENTREZGENE
  ENSMUST00000202447.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1280.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.30.390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemimethylated_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemimethylated_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SirB1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:231670 UniProtKB/Swiss-Prot
MGD MGI:1924223 ENTREZGENE
NCBI Gene Fbxo21 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SI:DKEY-261L7.2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transglut_core2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  YccV-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fbxo21 PhenoGen
PROSITE FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART YccV-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF141255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0J9YU92 ENTREZGENE, UniProtKB/TrEMBL
  FBX21_MOUSE UniProtKB/Swiss-Prot
  Q3TD93_MOUSE UniProtKB/TrEMBL
  Q8BHA5 ENTREZGENE
  Q8C658_MOUSE UniProtKB/TrEMBL
  Q8CHC6 ENTREZGENE
  Q8VDH1 ENTREZGENE
UniProt Secondary Q8BHA5 UniProtKB/Swiss-Prot
  Q8CHC6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Fbxo21  F-box protein 21  Fbxo21  F-box only protein 21  Symbol and/or name change 5135510 APPROVED
2024-08-21 Fbxo21  F-box only protein 21  Fbxo21  F-box protein 21  Symbol and/or name change 5135510 APPROVED