Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Adora2a (adenosine A2a receptor) Mus musculus
Analyze
Symbol: Adora2a
Name: adenosine A2a receptor
Description: Exhibits G protein-coupled adenosine receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; chemical synaptic transmission; and positive regulation of cell communication. Localizes to the plasma membrane. Predicted to colocalize with the intermediate filament. Used to study myopia and primary pulmonary hypertension. Human ortholog(s) of this gene implicated in asthma. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; intestine; and liver and biliary system. Orthologous to human ADORA2A (adenosine A2a receptor); PARTICIPATES IN adenosine signaling pathway; hypoxia inducible factor pathway; INTERACTS WITH (+)-pilocarpine; (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A2a, Rs; A2AAR; A2aR; AA2AR; adenosine receptor A2a; ARA2A; MGC118414
Orthologs:
Homo sapiens (human) : ADORA2A (adenosine A2a receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adora2a (adenosine A2a receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adora2a (adenosine A2a receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : ADORA2A (adenosine A2a receptor)
Canis lupus familiaris (dog) : ADORA2A (adenosine A2a receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adora2a (adenosine A2a receptor)
Sus scrofa (pig) : ADORA2A (adenosine A2a receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381075,316,877 - 75,334,792 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371074,779,688 - 74,797,533 (+)NCBIGRCm37mm9NCBIm37
MGSCv361074,769,745 - 74,777,652 (+)NCBImm8
Celera1076,363,966 - 76,382,118 (+)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adora2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10092
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.