C1qa (complement component 1, q subcomponent, alpha polypeptide) - Rat Genome Database

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Gene: C1qa (complement component 1, q subcomponent, alpha polypeptide) Mus musculus
Analyze
Symbol: C1qa
Name: complement component 1, q subcomponent, alpha polypeptide
RGD ID: 1315494
MGI Page MGI
Description: Involved in complement-mediated synapse pruning; glial cell activation; and nervous system development. Acts upstream of or within complement activation, classical pathway. Located in postsynapse. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic membrane and extrinsic component of presynaptic membrane. Is expressed in several structures, including brain; genitourinary system; lung; pancreas; and vestibular component mesenchyme. Used to study epilepsy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in glomerulonephritis. Orthologous to human C1QA (complement C1q A chain).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Adic; adiponectin c; AI255395; C1q; complement C1q subcomponent subunit A
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394136,623,227 - 136,626,155 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4136,623,228 - 136,626,114 (-)EnsemblGRCm39 Ensembl
GRCm384136,895,916 - 136,898,844 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,895,917 - 136,898,803 (-)EnsemblGRCm38mm10GRCm38
MGSCv374136,451,831 - 136,454,759 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364136,167,994 - 136,170,836 (-)NCBIMGSCv36mm8
Celera4135,103,233 - 135,106,157 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(R)-lipoic acid  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-butoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,7-dihydropurine-6-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxy-TEMPO  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
amitriptyline  (ISO)
amitrole  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (EXP,ISO)
astaxanthin  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
cannabidiol  (EXP)
captan  (EXP)
carbon nanotube  (EXP,ISO)
chlordecone  (EXP)
cisplatin  (ISO)
coenzyme Q10  (EXP)
Cuprizon  (ISO)
curcumin  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
dexamethasone  (EXP)
dextran sulfate  (EXP)
diclofenac  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
diuron  (ISO)
doramapimod  (EXP)
doxorubicin  (EXP,ISO)
ethanol  (EXP)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
fumonisin B1  (EXP)
genistein  (EXP)
gentamycin  (ISO)
heptachlor  (ISO)
indoles  (ISO)
ketamine  (ISO)
lansoprazole  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (EXP)
lycopene  (EXP)
medroxyprogesterone acetate  (ISO)
mercaptopurine  (ISO)
methcathinone  (ISO)
methimazole  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
O-acetyl-L-carnitine  (EXP)
ochratoxin A  (ISO)
omeprazole  (ISO)
ozone  (EXP)
paclitaxel  (ISO)
pantoprazole  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
purine-6-thiol  (ISO)
rabeprazole  (ISO)
resveratrol  (EXP,ISO)
silicon dioxide  (EXP)
sirolimus  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
Soman  (ISO)
streptozocin  (ISO)
tacrolimus hydrate  (EXP)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
trimellitic anhydride  (EXP)
trimethyltin  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Iron deficiency alters expression of genes implicated in Alzheimer disease pathogenesis. Carlson ES, etal., Brain Res. 2008 Aug 7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. The terminal pathway of the complement system is activated in focal penetrating but not in mild diffuse traumatic brain injury. Rostami E, etal., J Neurotrauma. 2013 Dec 1;30(23):1954-65. doi: 10.1089/neu.2012.2583. Epub 2013 Oct 30.
12. Molecular basis of hereditary C1q deficiency associated with SLE and IgA nephropathy in a Turkish family. Topaloglu R, etal., Kidney Int. 1996 Aug;50(2):635-42.
Additional References at PubMed
PMID:1940381   PMID:8606057   PMID:8878426   PMID:9590289   PMID:9607920   PMID:9611252   PMID:10047536   PMID:10047541   PMID:10072632   PMID:10229798   PMID:10349636   PMID:10934224  
PMID:11042159   PMID:11076747   PMID:11076861   PMID:11207648   PMID:11283677   PMID:11283678   PMID:11359841   PMID:11442749   PMID:11449362   PMID:11527969   PMID:11560991   PMID:11859149  
PMID:11869678   PMID:11901193   PMID:12133956   PMID:12244199   PMID:12432394   PMID:12452836   PMID:12477932   PMID:12794132   PMID:12794146   PMID:12930357   PMID:14971048   PMID:15147568  
PMID:15269255   PMID:15312138   PMID:15322019   PMID:15466618   PMID:15517607   PMID:15597324   PMID:15749852   PMID:15879138   PMID:15972690   PMID:16034123   PMID:16141072   PMID:16141073  
PMID:16166590   PMID:16179576   PMID:16272350   PMID:16517735   PMID:16602821   PMID:16615889   PMID:16651386   PMID:16670320   PMID:16778128   PMID:16869965   PMID:16943797   PMID:16944957  
PMID:16951374   PMID:16959763   PMID:16982912   PMID:17015700   PMID:17114482   PMID:17121989   PMID:17200212   PMID:17237437   PMID:17312136   PMID:17363917   PMID:17475881   PMID:17548593  
PMID:17675234   PMID:17675237   PMID:17785849   PMID:18083105   PMID:18198349   PMID:18287559   PMID:18400300   PMID:18501966   PMID:18541650   PMID:18572163   PMID:18624920   PMID:18672286  
PMID:19091977   PMID:19112490   PMID:19155476   PMID:19171874   PMID:19458267   PMID:19620499   PMID:19710463   PMID:19783052   PMID:19843088   PMID:20065024   PMID:20147536   PMID:20213737  
PMID:20223920   PMID:20375278   PMID:20410306   PMID:20416309   PMID:20810984   PMID:20829368   PMID:20870940   PMID:21123583   PMID:21235806   PMID:21257205   PMID:21263075   PMID:21308776  
PMID:21368058   PMID:21383504   PMID:21441447   PMID:21502587   PMID:21640391   PMID:21677750   PMID:21688269   PMID:21849679   PMID:21859968   PMID:21862594   PMID:21863053   PMID:21987785  
PMID:22037602   PMID:22142906   PMID:22262892   PMID:22427639   PMID:22457620   PMID:22566568   PMID:22679554   PMID:22682250   PMID:22721768   PMID:22794259   PMID:22918632   PMID:23028050  
PMID:23150673   PMID:23235303   PMID:23621154   PMID:23788643   PMID:23946404   PMID:24006456   PMID:24170856   PMID:24194600   PMID:24334446   PMID:24349316   PMID:24381160   PMID:24474777  
PMID:24591625   PMID:24740152   PMID:24804771   PMID:24945405   PMID:24952961   PMID:25039245   PMID:25091012   PMID:25132557   PMID:25326229   PMID:25467802   PMID:25716000   PMID:25753484  
PMID:25762679   PMID:26487714   PMID:26512759   PMID:26544197   PMID:26619292   PMID:26631482   PMID:26728245   PMID:26773156   PMID:26783342   PMID:26831747   PMID:26884166   PMID:27008854  
PMID:27033548   PMID:27048300   PMID:27109609   PMID:27114033   PMID:27173853   PMID:27304426   PMID:27573737   PMID:27626380   PMID:27644882   PMID:27687635   PMID:27731323   PMID:27876407  
PMID:28052876   PMID:28099414   PMID:28104818   PMID:28264694   PMID:28378742   PMID:28407005   PMID:28432146   PMID:28462915   PMID:28495878   PMID:28700664   PMID:28710441   PMID:28732515  
PMID:29167450   PMID:29279353   PMID:29437957   PMID:29497373   PMID:29724957   PMID:29941548   PMID:30126455   PMID:30250184   PMID:30325063   PMID:30471926   PMID:30635555   PMID:30652266  
PMID:31112138   PMID:31175160   PMID:31484074   PMID:31801075   PMID:31801811   PMID:31866375   PMID:31904875   PMID:32179479   PMID:32273396   PMID:32325033   PMID:32374620   PMID:32579912  
PMID:32682912   PMID:32692363   PMID:32719333   PMID:32765527   PMID:32866962   PMID:33147455   PMID:33177995   PMID:33239388   PMID:33323383   PMID:33620118   PMID:33628204   PMID:33746957  
PMID:34003106   PMID:34031614   PMID:34209320   PMID:34233165   PMID:34249009   PMID:34417332   PMID:34516796   PMID:34725868   PMID:34762332   PMID:34902359   PMID:35108544   PMID:35115674  
PMID:35167491   PMID:35278885   PMID:35442708   PMID:35711467   PMID:36280666   PMID:36417869   PMID:36625598   PMID:37159507   PMID:37356797   PMID:37562753   PMID:37635351   PMID:37726739  
PMID:38089576   PMID:38131301   PMID:38266812   PMID:38280374   PMID:38295788   PMID:38348774  


Genomics

Comparative Map Data
C1qa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394136,623,227 - 136,626,155 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4136,623,228 - 136,626,114 (-)EnsemblGRCm39 Ensembl
GRCm384136,895,916 - 136,898,844 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,895,917 - 136,898,803 (-)EnsemblGRCm38mm10GRCm38
MGSCv374136,451,831 - 136,454,759 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364136,167,994 - 136,170,836 (-)NCBIMGSCv36mm8
Celera4135,103,233 - 135,106,157 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.05NCBI
C1QA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,636,463 - 22,639,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl122,635,077 - 22,639,678 (+)EnsemblGRCh38hg38GRCh38
GRCh37122,962,956 - 22,966,171 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,835,705 - 22,838,762 (+)NCBINCBI36Build 36hg18NCBI36
Build 34122,709,405 - 22,711,405NCBI
Celera121,287,826 - 21,290,883 (+)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef121,207,463 - 21,210,520 (+)NCBIHuRef
CHM1_1123,075,637 - 23,078,694 (+)NCBICHM1_1
T2T-CHM13v2.0122,461,488 - 22,464,703 (+)NCBIT2T-CHM13v2.0
C1qa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85154,417,086 - 154,419,933 (-)NCBIGRCr8
mRatBN7.25149,133,635 - 149,136,482 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5149,133,636 - 149,136,534 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5151,831,406 - 151,834,253 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05153,605,693 - 153,608,540 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05153,587,691 - 153,590,538 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05155,261,254 - 155,264,101 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5155,261,250 - 155,264,143 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05159,023,753 - 159,026,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45155,662,333 - 155,665,180 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15155,672,371 - 155,675,219 (-)NCBI
Celera5147,531,382 - 147,534,229 (-)NCBICelera
Cytogenetic Map5q36NCBI
C1qa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554522,752,970 - 2,756,488 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554522,753,362 - 2,756,220 (+)NCBIChiLan1.0ChiLan1.0
C1QA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,668,086 - 76,671,082 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,668,217 - 76,670,977 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha273,172,967 - 73,175,970 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,227,331 - 77,230,335 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,227,333 - 77,230,230 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,048,204 - 74,051,200 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,056,639 - 75,059,641 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0276,060,247 - 76,063,252 (-)NCBIUU_Cfam_GSD_1.0
C1qa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505842,183,130 - 42,185,545 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364748,008,534 - 8,010,191 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364748,007,953 - 8,010,591 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C1QA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl680,586,280 - 80,589,204 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1680,586,259 - 80,589,213 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2674,610,025 - 74,612,855 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C1QA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120110,024,847 - 110,027,868 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660336,286,037 - 6,289,144 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
C1qa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247647,363,567 - 7,366,617 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247647,363,615 - 7,366,408 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C1qa
237 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:216
Count of miRNA genes:191
Interacting mature miRNAs:205
Transcripts:ENSMUST00000046285
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301793Tlsr3_mthymic lymphoma suppressor region 3 (mouse)Not determined4129465811136864536Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
4142082Psds2_mpsoriasis-like skin disease severity 2 (mouse)Not determined4133154678137617995Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse

Markers in Region
AI255395  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,896,287 - 136,896,399UniSTSGRCm38
MGSCv374136,452,202 - 136,452,314UniSTSGRCm37
Celera4135,103,604 - 135,103,716UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.1UniSTS
Whitehead/MRC_RH41802.48UniSTS
X58861  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,895,925 - 136,896,004UniSTSGRCm38
MGSCv374136,451,840 - 136,451,919UniSTSGRCm37
Celera4135,103,242 - 135,103,321UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.1UniSTS
Whitehead/MRC_RH41802.48UniSTS
UniSTS:485504  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Celera4135,103,855 - 135,105,409UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000046285   ⟹   ENSMUSP00000048836
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4136,623,228 - 136,626,114 (-)Ensembl
GRCm38.p6 Ensembl4136,895,917 - 136,898,803 (-)Ensembl
RefSeq Acc Id: NM_007572   ⟹   NP_031598
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394136,623,227 - 136,626,155 (-)NCBI
GRCm384136,895,916 - 136,898,844 (-)ENTREZGENE
MGSCv374136,451,831 - 136,454,759 (-)RGD
Celera4135,103,233 - 135,106,157 (-)RGD
cM Map4 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_031598   ⟸   NM_007572
- Peptide Label: precursor
- UniProtKB: Q9DCM6 (UniProtKB/Swiss-Prot),   P98086 (UniProtKB/Swiss-Prot),   A0A3B0IP04 (UniProtKB/TrEMBL),   Q3TXB1 (UniProtKB/TrEMBL),   Q3UBX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000048836   ⟸   ENSMUST00000046285
Protein Domains
C1q   Collagen-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P98086-F1-model_v2 AlphaFold P98086 1-245 view protein structure

Promoters
RGD ID:6847789
Promoter ID:MM_ACW:36131
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:C1QA.BSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364136,453,841 - 136,454,341 (-)MPROMDB
RGD ID:6834968
Promoter ID:MM_KWN:40235
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:NM_007572
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364136,454,431 - 136,454,931 (-)MPROMDB
RGD ID:6885136
Promoter ID:EPDNEW_M6019
Type:initiation region
Name:C1qa_1
Description:Mus musculus complement component 1, q subcomponent, alpha polypeptide, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384136,898,769 - 136,898,829EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88223 AgrOrtholog
Ensembl Genes ENSMUSG00000036887 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000046285 ENTREZGENE
  ENSMUST00000046285.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C1q_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Collagen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12259 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88223 ENTREZGENE
NCBI Gene 12259 ENTREZGENE
PANTHER EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15427:SF26 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1q UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Collagen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen C1qa PhenoGen
PRINTS COMPLEMNTC1Q UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART C1Q UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B0IP04 ENTREZGENE, UniProtKB/TrEMBL
  C1QA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TXB1 ENTREZGENE, UniProtKB/TrEMBL
  Q3UBX7 ENTREZGENE, UniProtKB/TrEMBL
  Q9DCM6 ENTREZGENE
UniProt Secondary Q9DCM6 UniProtKB/Swiss-Prot