Il10 (interleukin 10) - Rat Genome Database

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Gene: Il10 (interleukin 10) Mus musculus
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Symbol: Il10
Name: interleukin 10
RGD ID: 10785
MGI Page MGI
Description: Enables cytokine activity. Involved in several processes, including negative regulation of cell death; negative regulation of vascular associated smooth muscle cell proliferation; and positive regulation of sprouting angiogenesis. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus; negative regulation of cytokine production; and response to bacterium. Located in extracellular space. Is expressed in colon; liver; thymus; and thymus primordium. Used to study inflammatory bowel disease. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Orthologous to human IL10 (interleukin 10).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CSIF; cytokine synthesis inhibitory factor; If2a; IL-; Il-10; interferon 2a; interleukin-10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,947,459 - 130,952,707 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1130,947,582 - 130,952,711 (+)EnsemblGRCm39 Ensembl
GRCm381131,019,845 - 131,024,970 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,019,845 - 131,024,974 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,916,422 - 132,921,547 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,847,393 - 132,852,516 (+)NCBIMGSCv36mm8
Celera1133,642,456 - 133,647,581 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View