Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) Mus musculus
Analyze
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
RGD ID: 10734
MGI Page MGI
Description: Enables 11-beta-hydroxysteroid dehydrogenase (NADP+) activity. Acts upstream of or within lung development. Predicted to be located in apical part of cell; nuclear membrane; and rough endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study cortisone reductase deficiency 2. Human ortholog(s) of this gene implicated in cortisone reductase deficiency; cortisone reductase deficiency 2; and obesity. Orthologous to human HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11beta-HSD-1; 11beta-HSD1A; 11beta-hydroxysteroid dehydrogenase type 1; corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,903,948 - 192,946,353 (-)NCBIGRCm39mm39
GRCm39 Ensembl1192,903,942 - 192,946,383 (-)Ensembl
GRCm381193,221,640 - 193,264,045 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,221,634 - 193,264,075 (-)EnsemblGRCm38mm10GRCm38
MGSCv371195,047,834 - 195,090,239 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,922,413 - 194,964,769 (-)NCBImm8
Celera1200,096,784 - 200,141,189 (-)NCBICelera
Cytogenetic Map1H6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
11-dehydrocorticosterone  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-nonylphenol  (ISO)
4-tert-Octylphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
7-oxolithocholic acid  (ISO)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
androstane-3,17-diol  (ISO)
arsenic acid  (EXP)
azathioprine  (ISO)
benzamide  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bezafibrate  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) adipate  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
CARBENOXOLONE  (EXP,ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (EXP,ISO)
cholic acid  (EXP)
chromium atom  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
corticosterone  (EXP,ISO)
cortisol  (ISO)
cortisone  (EXP,ISO)
crocidolite asbestos  (EXP,ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
deoxycholic acid  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
Di-n-hexyl phthalate  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
Dicyclohexyl phthalate  (ISO)
diethylstilbestrol  (ISO)
disulfiram  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
drospirenone  (ISO)
ethanol  (EXP,ISO)
fenofibrate  (ISO)
fipronil  (ISO)
fluoranthene  (ISO)
folic acid  (EXP)
fumonisin B1  (EXP)
furan  (ISO)
furosemide  (ISO)
genistein  (EXP,ISO)
glycochenodeoxycholic acid  (EXP)
glycolithocholic acid  (EXP)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
herbicide  (ISO)
hyodeoxycholic acid  (EXP)
indometacin  (ISO)
isotretinoin  (ISO)
kainic acid  (EXP)
ketamine  (ISO)
lipopolysaccharide  (EXP)
manganese(II) chloride  (ISO)
medroxyprogesterone acetate  (ISO)
mercaptopurine  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
metyrapone  (ISO)
mifepristone  (EXP,ISO)
monosodium L-glutamate  (EXP)
morphine  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nickel atom  (ISO)
nicotine  (EXP,ISO)
nitrofen  (ISO)
Nonylphenol  (ISO)
oxaliplatin  (ISO)
oxycodone  (ISO)
p-tert-Amylphenol  (ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorododecanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
prednisolone  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
Propiverine  (ISO)
prostaglandin E2  (ISO)
purine-6-thiol  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
SB 203580  (EXP)
serpentine asbestos  (EXP,ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
spironolactone  (EXP)
sulforaphane  (ISO)
taurolithocholic acid  (EXP)
tauroursodeoxycholic acid  (EXP,ISO)
tenofovir disoproxil fumarate  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
triadimefon  (ISO)
trimethyltin  (EXP,ISO)
triphenylstannane  (ISO)
troglitazone  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zinc protoporphyrin  (EXP)
zinc sulfate  (ISO)
ziram  (ISO)
zoledronic acid  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal fat pad morphology  (IAGP)
abnormal amniotic fluid composition  (IAGP)
abnormal bone marrow cell physiology  (IAGP)
abnormal brainstem morphology  (IAGP)
abnormal circulating cholesterol level  (IAGP)
abnormal circulating insulin level  (IAGP)
abnormal corticosterone level  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal eating behavior  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal epididymal fat pad morphology  (IAGP)
abnormal fibroblast proliferation  (IAGP)
abnormal food intake  (IAGP)
abnormal glucose homeostasis  (IEA)
abnormal glucose tolerance  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal lung development  (IAGP)
abnormal macrophage derived foam cell morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal skeletal muscle fiber morphology  (IAGP)
abnormal spatial learning  (IAGP)
absent alveolar lamellar bodies  (IAGP)
centrally nucleated skeletal muscle fibers  (IAGP)
decreased alveolar lamellar body number  (IAGP)
decreased body weight  (IAGP)
decreased cholesterol level  (IAGP)
decreased circulating corticosterone level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating LDL cholesterol level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased collagen level  (IAGP)
decreased lean body mass  (IAGP)
decreased macrophage cell number  (IAGP)
decreased quadriceps weight  (IAGP)
decreased surfactant secretion  (IAGP)
decreased susceptibility to atherosclerosis  (IAGP)
decreased susceptibility to weight gain  (IAGP)
decreased tibialis anterior weight  (IAGP)
decreased tumor necrosis factor secretion  (IAGP)
enlarged adrenal glands  (IAGP)
hepatic steatosis  (IAGP)
hyperlipidemia  (IAGP)
improved glucose tolerance  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased circulating HDL cholesterol level  (IAGP)
increased fibroblast proliferation  (IAGP)
increased food intake  (IAGP)
increased liver glycogen level  (IAGP)
increased skeletal muscle glycogen level  (IAGP)
increased subcutaneous adipose tissue amount  (IAGP)
skeletal muscle atrophy  (IAGP)
small alveolar lamellar bodies  (IAGP)
References

Additional References at PubMed
PMID:7851387   PMID:7873449   PMID:8889548   PMID:8940387   PMID:8973338   PMID:9370340   PMID:9405715   PMID:10349636   PMID:10411326   PMID:11042159   PMID:11076861   PMID:11145573  
PMID:11165006   PMID:11217851   PMID:11274359   PMID:11546766   PMID:11733403   PMID:11739957   PMID:11841241   PMID:12145154   PMID:12436336   PMID:12439781   PMID:12444044   PMID:12466851  
PMID:12477932   PMID:12765951   PMID:14652720   PMID:14681479   PMID:14715714   PMID:15044372   PMID:15047607   PMID:15072571   PMID:15095019   PMID:15145446   PMID:15277385   PMID:15586384  
PMID:15616008   PMID:15634910   PMID:15782199   PMID:16093320   PMID:16105819   PMID:16141072   PMID:16141073   PMID:16356929   PMID:16602821   PMID:16621520   PMID:16751407   PMID:16763061  
PMID:17008390   PMID:17170103   PMID:17311922   PMID:17588937   PMID:17640483   PMID:17702848   PMID:17898220   PMID:17912154   PMID:17947710   PMID:18073273   PMID:18174284   PMID:18245842  
PMID:18450962   PMID:18467433   PMID:18573267   PMID:18755798   PMID:18778749   PMID:18779947   PMID:19010388   PMID:19602102   PMID:19675138   PMID:20045394   PMID:20495186   PMID:20544861  
PMID:20739946   PMID:20943927   PMID:21106871   PMID:21198436   PMID:21215738   PMID:21267068   PMID:21304964   PMID:21308778   PMID:21350084   PMID:21411659   PMID:21491433   PMID:21677750  
PMID:21858045   PMID:21873635   PMID:22033707   PMID:22067318   PMID:22158867   PMID:22209663   PMID:22315313   PMID:22357964   PMID:22447855   PMID:22555437   PMID:22692684   PMID:22768329  
PMID:22940536   PMID:22962254   PMID:23125311   PMID:23170035   PMID:23197361   PMID:23267038   PMID:23303209   PMID:23349944   PMID:23362866   PMID:23383297   PMID:23415904   PMID:23512810  
PMID:23595884   PMID:23633532   PMID:23696835   PMID:23722901   PMID:23832962   PMID:23851218   PMID:23933573   PMID:24154525   PMID:24169553   PMID:24381005   PMID:24413279   PMID:24511146  
PMID:24569863   PMID:24580729   PMID:24667799   PMID:24759003   PMID:24889609   PMID:24952961   PMID:25061560   PMID:25109766   PMID:25389364   PMID:25614240   PMID:25708481   PMID:25869616  
PMID:26268211   PMID:26305481   PMID:26465199   PMID:26563879   PMID:26700460   PMID:27070821   PMID:27195053   PMID:27384305   PMID:27566776   PMID:27578244   PMID:27841334   PMID:27859809  
PMID:28237720   PMID:28254522   PMID:28368470   PMID:28522730   PMID:28663379   PMID:28676523   PMID:28749080   PMID:29062028   PMID:29162555   PMID:29203512   PMID:29474943   PMID:29891135  
PMID:30902677   PMID:33162397   PMID:33214595   PMID:34072239   PMID:34292881   PMID:34490902  


Genomics

Comparative Map Data
Hsd11b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,903,948 - 192,946,353 (-)NCBIGRCm39mm39
GRCm39 Ensembl1192,903,942 - 192,946,383 (-)Ensembl
GRCm381193,221,640 - 193,264,045 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,221,634 - 193,264,075 (-)EnsemblGRCm38mm10GRCm38
MGSCv371195,047,834 - 195,090,239 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,922,413 - 194,964,769 (-)NCBImm8
Celera1200,096,784 - 200,141,189 (-)NCBICelera
Cytogenetic Map1H6NCBI
HSD11B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1209,686,178 - 209,734,949 (+)EnsemblGRCh38hg38GRCh38
GRCh381209,686,179 - 209,734,929 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371209,859,524 - 209,908,274 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361207,926,173 - 207,974,918 (+)NCBINCBI36hg18NCBI36
Build 341206,266,585 - 206,296,690NCBI
Celera1183,090,437 - 183,139,187 (+)NCBI
Cytogenetic Map1q32.2NCBI
HuRef1180,534,794 - 180,583,575 (+)NCBIHuRef
CHM1_11211,131,921 - 211,180,673 (+)NCBICHM1_1
Hsd11b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.213104,728,539 - 104,798,884 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl13104,728,539 - 104,788,687 (-)Ensembl
Rnor_6.013111,946,626 - 111,996,536 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13111,926,442 - 111,972,603 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,502,230 - 116,551,778 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413109,063,491 - 109,089,468 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113109,252,609 - 109,278,318 (-)NCBI
Celera13104,178,893 - 104,204,865 (-)NCBICelera
Cytogenetic Map13q27NCBI
Hsd11b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554892,497,680 - 2,524,805 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554892,500,928 - 2,524,715 (-)NCBIChiLan1.0ChiLan1.0
HSD11B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11190,086,449 - 190,116,765 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1190,086,449 - 190,116,765 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01185,262,599 - 185,311,417 (+)NCBIMhudiblu_PPA_v0panPan3
HSD11B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,344,380 - 8,409,901 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,344,447 - 8,409,897 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha77,959,522 - 7,986,906 (+)NCBI
ROS_Cfam_1.078,045,319 - 8,110,393 (+)NCBI
ROS_Cfam_1.0 Ensembl78,045,392 - 8,110,389 (+)Ensembl
UMICH_Zoey_3.178,012,426 - 8,039,787 (+)NCBI
UNSW_CanFamBas_1.078,109,437 - 8,136,847 (+)NCBI
UU_Cfam_GSD_1.078,170,917 - 8,198,302 (+)NCBI
Hsd11b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934466,118,456 - 66,179,043 (-)NCBI
SpeTri2.0NW_0049365573,358,809 - 3,403,461 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSD11B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9133,231,451 - 133,278,396 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19133,231,451 - 133,278,396 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HSD11B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12519,720,096 - 19,772,806 (-)NCBIChlSab1.1chlSab2
ChlSab1.12519,720,096 - 19,772,806 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2519,719,848 - 19,750,200 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605520,319,360 - 20,369,697 (-)NCBIVero_WHO_p1.0
Hsd11b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248072,260,702 - 2,293,962 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
X83202  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381193,221,810 - 193,221,961UniSTSGRCm38
MGSCv371195,048,004 - 195,048,155UniSTSGRCm37
Celera1200,096,954 - 200,097,105UniSTS
Cytogenetic Map1H6UniSTS
Whitehead/MRC_RH12445.75UniSTS
Whitehead_YAC1 UniSTS
D1Mit512  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381193,241,186 - 193,241,301UniSTSGRCm38
MGSCv371195,067,380 - 195,067,495UniSTSGRCm37
Celera1200,116,214 - 200,116,329UniSTS
Cytogenetic Map1H6UniSTS
cM Map1109.6UniSTS
Whitehead Genetic1113.7UniSTS
Whitehead/MRC_RH12445.75UniSTS
Whitehead_YAC1 UniSTS
Hsd11b1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H6UniSTS
cM Map197.67UniSTS
X83202  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381193,221,897 - 193,222,014UniSTSGRCm38
MGSCv371195,048,091 - 195,048,208UniSTSGRCm37
Celera1200,097,041 - 200,097,158UniSTS
Cytogenetic Map1H6UniSTS
Whitehead/MRC_RH12445.75UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172571254195471971Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167730317195471971Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167730317195471971Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1168222387195471971Mouse
1302023Orch4_mautoimmune orchitis resistance 4 (mouse)Not determined1175529010195471971Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167730317195471971Mouse
1357732Tbbmd1_mtotal body bone mineral density 1 (mouse)Not determined1172250913195471971Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1166092111195471971Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168481626195471971Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170647303195471971Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
10043863Swrl5_mSWR lupus locus 5 (mouse)Not determined1172571254195471971Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
11049575Lmr8b_mleishmaniasis resistance 8b (mouse)1172571254195471971Mouse
12880426V25Dq2_mvitamin D inactive form serum level QTL 2 (mouse)1172800000195471971Mouse
11532690Sluc37_msusceptibility to lung cancer 37 (mouse)1175641251194429220Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
12880429V25Dq1_mvitamin D inactive form serum level QTL 1 (mouse)1172900000195471971Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:698
Count of miRNA genes:383
Interacting mature miRNAs:459
Transcripts:ENSMUST00000016338, ENSMUST00000159644, ENSMUST00000160929, ENSMUST00000161406, ENSMUST00000161737, ENSMUST00000162842
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001044751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC022675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI099306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI132676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI182353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL365322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ812546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ089001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S75207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X92186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000016338   ⟹   ENSMUSP00000016338
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1192,903,942 - 192,924,937 (-)Ensembl
GRCm38.p6 Ensembl1193,221,634 - 193,242,629 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159644   ⟹   ENSMUSP00000124693
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1192,905,949 - 192,925,869 (-)Ensembl
GRCm38.p6 Ensembl1193,223,641 - 193,243,561 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160929   ⟹   ENSMUSP00000123849
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1192,903,990 - 192,923,906 (-)Ensembl
GRCm38.p6 Ensembl1193,221,682 - 193,241,598 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161406   ⟹   ENSMUSP00000124142
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1192,911,762 - 192,922,718 (-)Ensembl
GRCm38.p6 Ensembl1193,229,454 - 193,240,410 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161737   ⟹   ENSMUSP00000125620
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1192,903,997 - 192,946,383 (-)Ensembl
GRCm38.p6 Ensembl1193,221,689 - 193,264,075 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162842
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1192,920,582 - 192,923,732 (-)Ensembl
GRCm38.p6 Ensembl1193,238,274 - 193,241,424 (-)Ensembl
RefSeq Acc Id: ENSMUST00000191977
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1192,919,354 - 192,921,331 (-)Ensembl
GRCm38.p6 Ensembl1193,237,046 - 193,239,023 (-)Ensembl
RefSeq Acc Id: NM_001044751   ⟹   NP_001038216
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391192,903,948 - 192,924,668 (-)NCBI
GRCm381193,221,640 - 193,242,360 (-)NCBI
MGSCv371195,047,834 - 195,090,239 (-)RGD
Celera1200,096,784 - 200,141,189 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_008288   ⟹   NP_032314
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391192,903,948 - 192,946,353 (-)NCBI
GRCm381193,221,640 - 193,264,045 (-)NCBI
MGSCv371195,047,834 - 195,090,239 (-)RGD
Celera1200,096,784 - 200,141,189 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497228   ⟹   XP_006497291
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391192,903,994 - 192,925,802 (-)NCBI
GRCm381193,221,686 - 193,243,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249832   ⟹   XP_030105692
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391192,903,994 - 192,946,329 (-)NCBI
GRCm381193,221,686 - 193,264,021 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032314   ⟸   NM_008288
- UniProtKB: P50172 (UniProtKB/Swiss-Prot),   Q4JHD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001038216   ⟸   NM_001044751
- UniProtKB: P50172 (UniProtKB/Swiss-Prot),   Q4JHD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006497291   ⟸   XM_006497228
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030105692   ⟸   XM_030249832
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000124693   ⟸   ENSMUST00000159644
RefSeq Acc Id: ENSMUSP00000123849   ⟸   ENSMUST00000160929
RefSeq Acc Id: ENSMUSP00000016338   ⟸   ENSMUST00000016338
RefSeq Acc Id: ENSMUSP00000124142   ⟸   ENSMUST00000161406
RefSeq Acc Id: ENSMUSP00000125620   ⟸   ENSMUST00000161737

Promoters
RGD ID:6876166
Promoter ID:EPDNEW_M1534
Type:multiple initiation site
Name:Hsd11b1_3
Description:Mus musculus hydroxysteroid 11-beta dehydrogenase 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1535  EPDNEW_M1536  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381193,241,515 - 193,241,575EPDNEW
RGD ID:6876168
Promoter ID:EPDNEW_M1535
Type:multiple initiation site
Name:Hsd11b1_1
Description:Mus musculus hydroxysteroid 11-beta dehydrogenase 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1534  EPDNEW_M1536  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381193,242,357 - 193,242,417EPDNEW
RGD ID:6876170
Promoter ID:EPDNEW_M1536
Type:initiation region
Name:Hsd11b1_2
Description:Mus musculus hydroxysteroid 11-beta dehydrogenase 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1534  EPDNEW_M1535  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381193,264,037 - 193,264,097EPDNEW
RGD ID:6817899
Promoter ID:MM_KWN:3358
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000079283
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361195,066,306 - 195,066,806 (-)MPROMDB
RGD ID:6817898
Promoter ID:MM_KWN:3359
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   Lung
Transcripts:OTTMUST00000075992,   UC007EEF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361195,067,449 - 195,067,949 (-)MPROMDB
RGD ID:6817897
Promoter ID:MM_KWN:3360
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   Brain,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000075989
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361195,068,506 - 195,069,742 (-)MPROMDB
RGD ID:6817895
Promoter ID:MM_KWN:3362
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung,   Spleen
Transcripts:OTTMUST00000075988
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361195,090,066 - 195,090,947 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103562 AgrOrtholog
Ensembl Genes ENSMUSG00000016194 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000016338 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000123849 UniProtKB/TrEMBL
  ENSMUSP00000124142 UniProtKB/TrEMBL
  ENSMUSP00000124693 UniProtKB/TrEMBL
  ENSMUSP00000125620 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000016338 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000159644 UniProtKB/TrEMBL
  ENSMUST00000160929 UniProtKB/TrEMBL
  ENSMUST00000161406 UniProtKB/TrEMBL
  ENSMUST00000161737 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15483 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:103562 ENTREZGENE
NCBI Gene 15483 ENTREZGENE
Pfam adh_short UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hsd11b1 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DHI1_MOUSE UniProtKB/Swiss-Prot
  F2Z3U6_MOUSE UniProtKB/TrEMBL
  F6TSI8_MOUSE UniProtKB/TrEMBL
  P50172 ENTREZGENE
  Q3TJI8_MOUSE UniProtKB/TrEMBL
  Q4JHD9 ENTREZGENE, UniProtKB/TrEMBL