Ccn1 (cellular communication network factor 1) - Rat Genome Database

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Gene: Ccn1 (cellular communication network factor 1) Mus musculus
Symbol: Ccn1
Name: cellular communication network factor 1
RGD ID: 731721
Description: Enables extracellular matrix binding activity and integrin binding activity. Acts upstream of or within several processes, including circulatory system development; positive regulation of hydrolase activity; and regulation of apoptotic process. Located in collagen-containing extracellular matrix. Is expressed in several structures, including brain; cardiovascular system; embryo mesenchyme; sensory organ; and skeleton. Used to study atrial heart septal defect 1 and atrioventricular septal defect. Orthologous to human CCN1 (cellular communication network factor 1); INTERACTS WITH (R)-noradrenaline; (S)-nicotine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3CH61; AI325051; CCN; CCN family member 1; Cyr6; Cyr61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; IBP-10; IGF-binding protein 10; IGFBP-10; Igfbp10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm393145,352,726 - 145,355,740 (-)NCBIGRCm39mm39
GRCm39 Ensembl3145,352,731 - 145,355,736 (-)Ensembl
GRCm383145,646,971 - 145,649,985 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3145,646,976 - 145,649,981 (-)EnsemblGRCm38mm10GRCm38
MGSCv373145,309,935 - 145,312,949 (-)NCBIGRCm37mm9NCBIm37
MGSCv363145,584,362 - 145,587,367 (-)NCBImm8
Celera3152,099,713 - 152,102,726 (-)NCBICelera
Cytogenetic Map3H2NCBI
cM Map370.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(20S)-ginsenoside Rg3  (ISO)
(R)-noradrenaline  (EXP)
(S)-nicotine  (EXP)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3'-diindolylmethane  (ISO)
3,4-dichloroaniline  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
acetamide  (ISO)
acrylamide  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
aldrin  (EXP)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
antimycin A  (ISO)
aristolochic acid  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (ISO)
avobenzone  (ISO)
azathioprine  (ISO)
bacitracin  (ISO)
bazedoxifene  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buta-1,3-diene  (EXP)
butan-1-ol  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
calciol  (EXP)
calcitriol  (ISO)
capecitabine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carbonyl sulfide  (ISO)
casticin  (EXP)
chelerythrine  (EXP)
chloroprene  (EXP)
chloroquine  (ISO)
choline  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cumene  (EXP)
cyanidin cation  (EXP,ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
D-glucose  (EXP)
deoxynivalenol  (EXP)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxifluridine  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
Enterolactone  (ISO)
estriol  (EXP)
ethanol  (ISO)
fenamidone  (EXP)
fenofibrate  (ISO)
fluoranthene  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geranylgeraniol  (ISO)
glucose  (EXP)
glycidol  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (EXP)
hydroquinone  (ISO)
indole-3-methanol  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
jaspamide  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (EXP,ISO)
LY294002  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (EXP)
naphthalenes  (ISO)
nickel atom  (EXP,ISO)
nicotine  (EXP)
orphenadrine  (ISO)
oxaliplatin  (ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phosgene  (EXP)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
prednisolone  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
rifampicin  (ISO)
ritodrine  (EXP)
rotenone  (ISO)
SB 203580  (EXP)
SB 431542  (ISO)
SCH 23390  (ISO)
sclareol  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
succimer  (EXP,ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
tetradecane  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
torcetrapib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
undecane  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vancomycin  (ISO)
verteporfin  (EXP,ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process involved in heart morphogenesis  (IMP)
atrial septum morphogenesis  (IMP)
atrioventricular valve morphogenesis  (IMP)
cell adhesion  (IBA,IDA,ISO)
cell-cell adhesion  (IDA)
chemotaxis  (ISO)
chondroblast differentiation  (IDA)
chorio-allantoic fusion  (IMP)
extracellular matrix organization  (IDA)
intussusceptive angiogenesis  (IMP)
labyrinthine layer blood vessel development  (IMP)
negative regulation of apoptotic process  (IMP)
negative regulation of cell death  (IBA)
osteoblast differentiation  (IGI)
positive regulation of apoptotic process  (IGI)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of bone mineralization  (ISO)
positive regulation of cartilage development  (IMP)
positive regulation of cell differentiation  (IDA)
positive regulation of cell migration  (IDA,ISO)
positive regulation of cell-substrate adhesion  (IDA)
positive regulation of ceramide biosynthetic process  (IDA)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IGI)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-17 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of osteoblast proliferation  (ISO)
positive regulation of phospholipase activity  (IDA)
positive regulation of protein kinase activity  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
reactive oxygen species metabolic process  (IDA)
regulation of ERK1 and ERK2 cascade  (ISO)
signal transduction  (IBA)
ventricular septum development  (IMP)
wound healing, spreading of cells  (ISO)

Cellular Component

Molecular Function


Additional References at PubMed
PMID:1419914   PMID:2062642   PMID:2355916   PMID:7687569   PMID:9135077   PMID:9184077   PMID:9441684   PMID:10094812   PMID:10349636   PMID:10391928   PMID:10821835   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:12036876   PMID:12231560   PMID:12477932   PMID:12520002   PMID:12826661   PMID:14681479   PMID:15117851   PMID:15308622   PMID:15322081   PMID:15489334  
PMID:15492009   PMID:16141072   PMID:16141073   PMID:16581771   PMID:16602821   PMID:16869965   PMID:17023674   PMID:17234971   PMID:17318182   PMID:17765657   PMID:18554416   PMID:18597638  
PMID:18599605   PMID:18757743   PMID:18801924   PMID:19228596   PMID:19364818   PMID:19542562   PMID:20133625   PMID:20526329   PMID:20637190   PMID:20641097   PMID:20675382   PMID:21153366  
PMID:21212276   PMID:21212405   PMID:21312266   PMID:21382954   PMID:21536733   PMID:21873635   PMID:22056874   PMID:22532143   PMID:22547695   PMID:23027863   PMID:23071295   PMID:23329650  
PMID:23457573   PMID:23508104   PMID:23658023   PMID:23690222   PMID:23798676   PMID:23839921   PMID:23863479   PMID:24006456   PMID:24043783   PMID:24142710   PMID:24196529   PMID:24280864  
PMID:24371135   PMID:24391734   PMID:24430538   PMID:24487063   PMID:24517278   PMID:24593181   PMID:24859262   PMID:24880616   PMID:24895995   PMID:24910328   PMID:24920753   PMID:24952961  
PMID:25065593   PMID:25106095   PMID:25321413   PMID:25623072   PMID:25712640   PMID:25713320   PMID:25807183   PMID:25822023   PMID:25912685   PMID:26002917   PMID:26028023   PMID:26033091  
PMID:26077348   PMID:26174800   PMID:26242736   PMID:26363286   PMID:26416771   PMID:26459773   PMID:26496610   PMID:26625209   PMID:27167338   PMID:27358050   PMID:27465842   PMID:27482114  
PMID:27694478   PMID:27760754   PMID:27856305   PMID:27889647   PMID:28087714   PMID:28118982   PMID:28157379   PMID:28341837   PMID:28469167   PMID:28602508   PMID:28742024   PMID:28893950  
PMID:28935707   PMID:28943241   PMID:29351359   PMID:29401606   PMID:29513653   PMID:29659575   PMID:30037926   PMID:30128877   PMID:30635555   PMID:30789911   PMID:30912742   PMID:30917686  
PMID:31062503   PMID:31073041   PMID:31107624   PMID:31220272   PMID:31262999   PMID:31323030   PMID:31575647   PMID:31606201   PMID:31747096   PMID:32009252   PMID:32081971   PMID:32144270  
PMID:32186512   PMID:32243503   PMID:32325033   PMID:32634285   PMID:32886109   PMID:32936024   PMID:33195213   PMID:33483469   PMID:33574403   PMID:33875791   PMID:34267330  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm393145,352,726 - 145,355,740 (-)NCBIGRCm39mm39
GRCm39 Ensembl3145,352,731 - 145,355,736 (-)Ensembl
GRCm383145,646,971 - 145,649,985 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3145,646,976 - 145,649,981 (-)EnsemblGRCm38mm10GRCm38
MGSCv373145,309,935 - 145,312,949 (-)NCBIGRCm37mm9NCBIm37
MGSCv363145,584,362 - 145,587,367 (-)NCBImm8
Celera3152,099,713 - 152,102,726 (-)NCBICelera
Cytogenetic Map3H2NCBI
cM Map370.18NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl185,580,761 - 85,584,589 (+)EnsemblGRCh38hg38GRCh38
GRCh38185,580,761 - 85,583,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37186,046,444 - 86,049,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36185,819,048 - 85,821,978 (+)NCBINCBI36hg18NCBI36
Build 34185,758,480 - 85,761,410NCBI
Celera184,290,551 - 84,293,757 (+)NCBI
Cytogenetic Map1p22.3NCBI
HuRef184,157,232 - 84,160,438 (+)NCBIHuRef
CHM1_1186,161,864 - 86,165,070 (+)NCBICHM1_1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.22234,562,410 - 234,565,370 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2234,562,408 - 234,565,484 (-)Ensembl
Rnor_6.02251,529,354 - 251,532,312 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2251,529,354 - 251,532,312 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02270,055,954 - 270,058,912 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42243,824,303 - 243,827,262 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12243,811,042 - 243,814,002 (-)NCBI
Celera2226,551,241 - 226,554,210 (-)NCBICelera
Cytogenetic Map2q44NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049554238,413,725 - 8,419,166 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554238,416,498 - 8,419,029 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1186,994,296 - 86,997,147 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl186,994,296 - 86,997,147 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01118,138,739 - 118,141,681 (+)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1662,443,285 - 62,446,246 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl662,443,675 - 62,445,994 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha665,092,607 - 65,095,413 (-)NCBI
ROS_Cfam_1.0662,984,109 - 62,986,915 (-)NCBI
UMICH_Zoey_3.1662,514,247 - 62,517,060 (-)NCBI
UNSW_CanFamBas_1.0662,482,278 - 62,484,463 (-)NCBI
UU_Cfam_GSD_1.0662,986,500 - 62,989,314 (-)NCBI
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440505896,150,919 - 96,153,859 (+)NCBI
SpeTri2.0NW_004936608152,174 - 155,123 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl4130,392,404 - 130,395,150 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14130,392,404 - 130,395,179 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24142,924,666 - 142,927,450 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.12047,783,270 - 47,786,216 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2047,783,935 - 47,785,997 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603370,022,961 - 70,025,930 (+)NCBIVero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_00462474211,882,815 - 11,885,686 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383145,647,132 - 145,647,257UniSTSGRCm38
MGSCv373145,310,096 - 145,310,221UniSTSGRCm37
Celera3152,099,874 - 152,099,999UniSTS
Cytogenetic Map3H2UniSTS
cM Map372.9UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383145,651,045 - 145,651,180UniSTSGRCm38
MGSCv373145,314,009 - 145,314,144UniSTSGRCm37
Celera3152,103,785 - 152,103,920UniSTS
Cytogenetic Map3H2UniSTS
cM Map372.9UniSTS
Whitehead Genetic351.4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383145,651,195 - 145,651,337UniSTSGRCm38
MGSCv373145,314,159 - 145,314,301UniSTSGRCm37
Celera3152,103,935 - 152,104,077UniSTS
Cytogenetic Map3H2UniSTS
cM Map372.9UniSTS
cM Map3 UniSTS
Whitehead Genetic351.4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383145,650,893 - 145,651,060UniSTSGRCm38
MGSCv373145,313,857 - 145,314,024UniSTSGRCm37
Celera3152,103,633 - 152,103,800UniSTS
Cytogenetic Map3H2UniSTS
cM Map372.9UniSTS
cM Map3 UniSTS
Whitehead Genetic351.4UniSTS
Whitehead_YAC3 UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383145,647,239 - 145,647,832UniSTSGRCm38
MGSCv373145,310,346 - 145,311,726UniSTSGRCm37
Celera3152,099,981 - 152,100,573UniSTS
Cytogenetic Map3H2UniSTS
cM Map372.9UniSTS
cM Map372.9UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383145,647,382 - 145,648,762UniSTSGRCm38
MGSCv373145,310,346 - 145,311,726UniSTSGRCm37
Celera3152,100,123 - 152,101,503UniSTS
Cytogenetic Map3H2UniSTS
cM Map372.9UniSTS

QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330013439147599053Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396700000148100000Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100465596147339967Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101400000150100000Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107469620147599053Mouse
1301100Bdt2_mbone density traits 2 (mouse)Not determined3115030856149031023Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119351571153351695Mouse
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119351571153351695Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119612825153612825Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119612825153612825Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3120073096154073283Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3121066317155066317Mouse
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126564487160039680Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126647225160039680Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126754753160039680Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3131031299160039680Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3131143739160039680Mouse
1300753Eae10_msusceptibility to experimental allergic encephalomyelitis 10 (mouse)Not determined3132030856148745542Mouse
10412120Ccs3_mcolon cancer susceptibility 3 (mouse)Not determined3132048775146311914Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133756256160039680Mouse
1301221Hrtfm2_mheart failure modifier 2 (mouse)Not determined3143564487147339967Mouse
1301222Scc7_mcolon tumor susceptibility 7 (mouse)Not determined3143647225156658471Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID

Predicted Target Of
Summary Value
Count of predictions:214
Count of miRNA genes:160
Interacting mature miRNAs:181
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.



Reference Sequences
RefSeq Acc Id: ENSMUST00000029846   ⟹   ENSMUSP00000029846
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3145,352,731 - 145,355,736 (-)Ensembl
GRCm38.p6 Ensembl3145,646,976 - 145,649,981 (-)Ensembl
RefSeq Acc Id: NM_010516   ⟹   NP_034646
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm393145,352,726 - 145,355,740 (-)NCBI
GRCm383145,646,971 - 145,649,985 (-)ENTREZGENE
MGSCv373145,309,935 - 145,312,949 (-)RGD
Celera3152,099,713 - 152,102,726 (-)RGD
Reference Sequences
RefSeq Acc Id: NP_034646   ⟸   NM_010516
- Peptide Label: precursor
- UniProtKB: P18406 (UniProtKB/Swiss-Prot),   Q3TX21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000029846   ⟸   ENSMUST00000029846
Protein Domains
CTCK   IGFBP N-terminal   TSP type-1   VWFC

RGD ID:6833617
Promoter ID:MM_KWN:36341
SO ACC ID:SO:0000170
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Mouse AssemblyChrPosition (strand)Source
MGSCv363145,312,486 - 145,313,777 (-)MPROMDB
RGD ID:6882576
Promoter ID:EPDNEW_M4739
Type:multiple initiation site
Description:Mus musculus cysteine rich protein 61 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm383145,649,981 - 145,650,041EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88613 AgrOrtholog
Ensembl Genes ENSMUSG00000028195 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000029846 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000029846 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cys_knot_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hormone_CN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP_CNN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin_GF-bd_Cys-rich_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_CCN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16007 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cys_knot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_CCN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccn1 PhenoGen
PROSITE CTCK_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTCK_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP_N_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWFC_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWFC_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00041 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00121 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CYR61_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-13 Ccn1  cellular communication network factor 1  Cyr61  cysteine rich protein 61  Symbol and/or name change 5135510 APPROVED