Cd55 (CD55 molecule, decay accelerating factor for complement) - Rat Genome Database

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Gene: Cd55 (CD55 molecule, decay accelerating factor for complement) Mus musculus
Analyze
Symbol: Cd55
Name: CD55 molecule, decay accelerating factor for complement
RGD ID: 734384
MGI Page MGI
Description: Predicted to enable enzyme inhibitor activity; lipid binding activity; and virus receptor activity. Acts upstream of or within regulation of complement activation, classical pathway. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; liver and biliary system; and nervous system. Human ortholog(s) of this gene implicated in prostate cancer and protein-losing enteropathy. Orthologous to human CD55 (CD55 molecule (Cromer blood group)).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CD55 antigen; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; Cromer blood group; Daf; Daf-; Daf-GPI; Daf1; decay accelerating factor 1; GPI anchor addition signal; GPI-; GPI-DAF
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,357,526 - 130,390,513 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1130,366,764 - 130,390,481 (-)EnsemblGRCm39 Ensembl
GRCm381130,429,798 - 130,465,009 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,439,027 - 130,462,744 (-)EnsemblGRCm38mm10GRCm38
MGSCv371132,335,606 - 132,359,317 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,267,758 - 132,290,230 (-)NCBIMGSCv36mm8
Celera1133,067,523 - 133,091,208 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
AM-251  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antimycin A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
butyric acid  (ISO)
cadmium selenide  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
chlormequat chloride  (ISO)
chloroprene  (EXP)
chromium(6+)  (ISO)
chrysene  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
etoposide  (ISO)
fenoldopam  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
gentamycin  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP)
mercury dichloride  (EXP)
metam  (EXP)
methamphetamine  (ISO)
methidathion  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mitoxantrone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
niclosamide  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
potassium dichromate  (EXP)
propanal  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sulfasalazine  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
torcetrapib  (ISO)
Tributyltin oxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
tunicamycin  (EXP,ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes. Bao L, etal., Kidney Int. 2002 Dec;62(6):2010-21.
2. Potent oncolytic activity of human enteroviruses against human prostate cancer. Berry LJ, etal., Prostate. 2008 May 1;68(6):577-87.
3. CD59 expressed on a tumor cell surface modulates decay-accelerating factor expression and enhances tumor growth in a rat model of human neuroblastoma. Chen S, etal., Cancer Res. 2000 Jun 1;60(11):3013-8.
4. Human and rodent decay-accelerating factors (CD55) are not species restricted in their complement-inhibiting activities. Harris CL, etal., Immunology. 2000 Aug;100(4):462-70.
5. CD80 Regulates Th17 Cell Differentiation in Coxsackie Virus B3-Induced Acute Myocarditis. Huang Y, etal., Inflammation. 2018 Feb;41(1):232-239. doi: 10.1007/s10753-017-0681-7.
6. Prognostic significance of CD55 expression in breast cancer. Ikeda J, etal., Clin Cancer Res. 2008 Aug 1;14(15):4780-6.
7. Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay-accelerating factor protection. Lin F, etal., J Clin Invest 2002 Nov;110(9):1269-74.
8. Inhibition of decay-accelerating factor (CD55) attenuates prostate cancer growth and survival in vivo. Loberg RD, etal., Neoplasia. 2006 Jan;8(1):69-78.
9. Loss of CD55 is associated with aggressive breast tumors. Madjd Z, etal., Clin Cancer Res. 2004 Apr 15;10(8):2797-803.
10. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. Expression of decay accelerating factor in endometrial adenocarcinoma is inversely related to the stage of tumor. Nowicki S, etal., Am J Reprod Immunol. 2001 Aug;46(2):144-8.
14. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection. Ramlall V, etal., Nat Med. 2020 Aug 3. pii: 10.1038/s41591-020-1021-2. doi: 10.1038/s41591-020-1021-2.
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Expression of the complement regulatory proteins decay accelerating factor (DAF, CD55), membrane cofactor protein (MCP, CD46) and CD59 in the normal human uterine cervix and in premalignant and malignant cervical disease. Simpson KL, etal., Am J Pathol. 1997 Nov;151(5):1455-67.
20. Postconditioning attenuates renal ischemia-reperfusion injury by preventing DAF down-regulation. Wang W, etal., J Urol. 2010 Jun;183(6):2424-31. Epub 2010 Apr 18.
21. Coxsackievirus B3-associated myocardial pathology and viral load reduced by recombinant soluble human decay-accelerating factor in mice. Yanagawa B, etal., Lab Invest. 2003 Jan;83(1):75-85.
Additional References at PubMed
PMID:7545711   PMID:8540104   PMID:8671624   PMID:8892654   PMID:9435343   PMID:9892684   PMID:10349636   PMID:10417349   PMID:10608785   PMID:10725249   PMID:10922068   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:11489951   PMID:11509624   PMID:11544199   PMID:11683961   PMID:11683962   PMID:11986227   PMID:12003997   PMID:12213736   PMID:12393518   PMID:12477932  
PMID:12914820   PMID:14670299   PMID:14764738   PMID:15004190   PMID:15004194   PMID:15561968   PMID:15710649   PMID:15883171   PMID:16141072   PMID:16141073   PMID:16284245   PMID:16421483  
PMID:16517735   PMID:16543227   PMID:16602821   PMID:16817758   PMID:16859686   PMID:16887189   PMID:17015743   PMID:17034582   PMID:17259999   PMID:17363730   PMID:17383432   PMID:17392165  
PMID:17530719   PMID:17709533   PMID:17947652   PMID:18178847   PMID:18424707   PMID:18524992   PMID:18567839   PMID:18802060   PMID:18947875   PMID:19036700   PMID:19136662   PMID:19168900  
PMID:19297024   PMID:19299737   PMID:19349693   PMID:19443714   PMID:19491392   PMID:19660813   PMID:19729477   PMID:20055803   PMID:20131275   PMID:20299685   PMID:20408894   PMID:20526042  
PMID:20840652   PMID:21166665   PMID:21169517   PMID:21652682   PMID:21704012   PMID:21816131   PMID:21873635   PMID:21984892   PMID:22325826   PMID:22987701   PMID:23109726   PMID:23204401  
PMID:23382542   PMID:23390291   PMID:23427256   PMID:23447688   PMID:23690475   PMID:23788643   PMID:24194600   PMID:24316575   PMID:24723363   PMID:25032961   PMID:25284781   PMID:25377281  
PMID:25596646   PMID:25993318   PMID:26149093   PMID:27245320   PMID:27494303   PMID:27929130   PMID:28057640   PMID:28838952   PMID:31091357   PMID:31103439   PMID:31146259   PMID:31217324  
PMID:32717081   PMID:34174788   PMID:35143305   PMID:37036696   PMID:38049580   PMID:38355793   PMID:38372645   PMID:39342308  


Genomics

Comparative Map Data
Cd55
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,357,526 - 130,390,513 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1130,366,764 - 130,390,481 (-)EnsemblGRCm39 Ensembl
GRCm381130,429,798 - 130,465,009 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,439,027 - 130,462,744 (-)EnsemblGRCm38mm10GRCm38
MGSCv371132,335,606 - 132,359,317 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,267,758 - 132,290,230 (-)NCBIMGSCv36mm8
Celera1133,067,523 - 133,091,208 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.89NCBI
CD55
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381207,321,678 - 207,360,966 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1207,321,519 - 207,386,804 (+)EnsemblGRCh38hg38GRCh38
GRCh371207,495,023 - 207,534,311 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,561,488 - 205,600,470 (+)NCBINCBI36Build 36hg18NCBI36
Build 341203,883,259 - 203,922,241NCBI
Celera1180,747,405 - 180,786,905 (+)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1178,191,283 - 178,230,783 (+)NCBIHuRef
CHM1_11208,767,582 - 208,807,063 (+)NCBICHM1_1
T2T-CHM13v2.01206,586,974 - 206,626,269 (+)NCBIT2T-CHM13v2.0
Cd55
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81344,409,574 - 44,438,913 (-)NCBIGRCr8
mRatBN7.21341,857,242 - 41,885,966 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1341,857,395 - 41,885,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1344,456,356 - 44,482,601 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01345,744,470 - 45,770,715 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01342,999,115 - 43,025,368 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01347,125,156 - 47,153,557 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,126,741 - 47,154,292 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01352,177,543 - 52,206,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,322,246 - 43,348,334 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11343,344,956 - 43,362,318 (-)NCBI
Celera1342,209,852 - 42,236,220 (-)NCBICelera
Cytogenetic Map13q13NCBI
Cd55
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540642,773,368 - 42,796,205 (+)NCBIChiLan1.0ChiLan1.0
CD55
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2142,015,372 - 42,054,589 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1141,981,330 - 42,020,548 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01182,923,369 - 182,962,518 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11187,201,195 - 187,240,350 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1187,201,081 - 187,240,350 (+)Ensemblpanpan1.1panPan2
CD55
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.176,361,037 - 6,396,063 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl76,360,964 - 6,386,226 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha75,923,634 - 5,949,508 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.076,049,135 - 6,075,038 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl76,049,143 - 6,077,363 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.175,982,465 - 6,008,341 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.076,084,489 - 6,110,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.076,125,081 - 6,150,968 (+)NCBIUU_Cfam_GSD_1.0
Cd55
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,104,286 - 68,123,978 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365575,344,373 - 5,364,234 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD55
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1967,933,069 - 67,960,380 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2974,368,906 - 74,393,140 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2974,313,866 - 74,314,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CD55
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,055,138 - 22,092,472 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2522,073,629 - 22,092,173 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605522,674,151 - 22,711,583 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd55
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248074,252,676 - 4,274,828 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:547
Count of miRNA genes:384
Interacting mature miRNAs:433
Transcripts:ENSMUST00000027650, ENSMUST00000122830, ENSMUST00000133057, ENSMUST00000140400, ENSMUST00000140725
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1301123Cd8mts2_mCD8 memory T cell subset 2 (mouse)Not determined196618386130618557Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197053986131054190Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199507660133507845Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse

Markers in Region
AI323748  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381130,461,850 - 130,461,933UniSTSGRCm38
GRCm381130,422,143 - 130,422,226UniSTSGRCm38
MGSCv371132,318,720 - 132,318,803UniSTSGRCm37
MGSCv371132,358,427 - 132,358,510UniSTSGRCm37
Celera1133,050,640 - 133,050,723UniSTS
Celera1133,090,318 - 133,090,401UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
cM Map167.6UniSTS
Whitehead/MRC_RH11722.0UniSTS
UniSTS:225316  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381130,440,064 - 130,440,214UniSTSGRCm38
MGSCv371132,336,641 - 132,336,791UniSTSGRCm37
Celera1133,068,558 - 133,068,708UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
Daf1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
C87253  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381130,439,126 - 130,439,341UniSTSGRCm38
GRCm381130,390,162 - 130,390,376UniSTSGRCm38
MGSCv371132,286,739 - 132,286,953UniSTSGRCm37
MGSCv371132,335,703 - 132,335,918UniSTSGRCm37
Celera1133,018,660 - 133,018,874UniSTS
Celera1133,067,620 - 133,067,835UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
cM Map167.6UniSTS
Whitehead/MRC_RH11719.05UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001404959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_175895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_175896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB003320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC111067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF143539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF143541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU515742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU222534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D63679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L41366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L41501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000027650   ⟹   ENSMUSP00000027650
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1130,366,764 - 130,390,481 (-)Ensembl
GRCm38.p6 Ensembl1130,439,027 - 130,462,744 (-)Ensembl
Ensembl Acc Id: ENSMUST00000122830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1130,367,891 - 130,376,586 (-)Ensembl
GRCm38.p6 Ensembl1130,440,154 - 130,448,849 (-)Ensembl
Ensembl Acc Id: ENSMUST00000133057
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1130,387,330 - 130,390,188 (-)Ensembl
GRCm38.p6 Ensembl1130,459,593 - 130,462,451 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140400   ⟹   ENSMUSP00000122294
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1130,374,398 - 130,380,153 (-)Ensembl
GRCm38.p6 Ensembl1130,446,661 - 130,452,416 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140725
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1130,374,398 - 130,390,468 (-)Ensembl
GRCm38.p6 Ensembl1130,446,661 - 130,462,731 (-)Ensembl
RefSeq Acc Id: NM_001404959   ⟹   NP_001391888
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,374,398 - 130,390,468 (-)NCBI
RefSeq Acc Id: NM_001404960   ⟹   NP_001391889
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,366,746 - 130,390,468 (-)NCBI
RefSeq Acc Id: NM_001420093   ⟹   NP_001407022
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,366,746 - 130,390,468 (-)NCBI
RefSeq Acc Id: NM_010016   ⟹   NP_034146
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,366,746 - 130,390,468 (-)NCBI
GRCm381130,439,026 - 130,462,744 (-)NCBI
MGSCv371132,335,606 - 132,359,317 (-)RGD
Celera1133,067,523 - 133,091,208 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_175895
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,366,766 - 130,390,245 (-)NCBI
RefSeq Acc Id: NR_175896
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,374,398 - 130,390,245 (-)NCBI
RefSeq Acc Id: XM_030246237   ⟹   XP_030102097
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,357,526 - 130,390,513 (-)NCBI
GRCm381130,437,464 - 130,465,009 (-)NCBI
Sequence:
RefSeq Acc Id: NP_034146   ⟸   NM_010016
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q921P0 (UniProtKB/Swiss-Prot),   Q76N72 (UniProtKB/Swiss-Prot),   Q61397 (UniProtKB/Swiss-Prot),   Q4FJS4 (UniProtKB/Swiss-Prot),   Q3TU32 (UniProtKB/Swiss-Prot),   P97732 (UniProtKB/Swiss-Prot),   Q9R1C1 (UniProtKB/Swiss-Prot),   Q61475 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030102097   ⟸   XM_030246237
- Peptide Label: isoform X2
Ensembl Acc Id: ENSMUSP00000027650   ⟸   ENSMUST00000027650
Ensembl Acc Id: ENSMUSP00000122294   ⟸   ENSMUST00000140400
RefSeq Acc Id: NP_001391889   ⟸   NM_001404960
- Peptide Label: isoform 3 preproprotein
RefSeq Acc Id: NP_001391888   ⟸   NM_001404959
- Peptide Label: isoform 2 preproprotein
RefSeq Acc Id: NP_001407022   ⟸   NM_001420093
- Peptide Label: isoform 4 preproprotein
Protein Domains
Sushi

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61475-F1-model_v2 AlphaFold Q61475 1-390 view protein structure

Promoters
RGD ID:6874818
Promoter ID:EPDNEW_M858
Type:initiation region
Name:Cd55_2
Description:Mus musculus CD55 molecule, decay accelerating factor for complement, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M859  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381130,448,727 - 130,448,787EPDNEW
RGD ID:6874816
Promoter ID:EPDNEW_M859
Type:initiation region
Name:Cd55_1
Description:Mus musculus CD55 molecule, decay accelerating factor for complement, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M858  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381130,462,716 - 130,462,776EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104850 AgrOrtholog
Ensembl Genes ENSMUSG00000026399 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027650 ENTREZGENE
  ENSMUST00000027650.13 UniProtKB/Swiss-Prot
  ENSMUST00000140400.2 UniProtKB/TrEMBL
Gene3D-CATH Complement Module, domain 1 UniProtKB/Swiss-Prot
InterPro Compl-Cell_Adhes-Reg UniProtKB/Swiss-Prot
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot
KEGG Report mmu:13136 UniProtKB/Swiss-Prot
MGD MGI:104850 ENTREZGENE
NCBI Gene 13136 ENTREZGENE
PANTHER COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  COMPLEMENT DECAY-ACCELERATING FACTOR UniProtKB/Swiss-Prot
Pfam Sushi UniProtKB/Swiss-Prot
PhenoGen Cd55 PhenoGen
PROSITE SUSHI UniProtKB/Swiss-Prot
SMART CCP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57535 UniProtKB/Swiss-Prot
UniProt DAF1_MOUSE UniProtKB/Swiss-Prot
  F7BP06_MOUSE UniProtKB/TrEMBL
  P97732 ENTREZGENE
  Q3TU32 ENTREZGENE
  Q4FJS4 ENTREZGENE
  Q61397 ENTREZGENE
  Q61475 ENTREZGENE
  Q76N72 ENTREZGENE
  Q921P0 ENTREZGENE
  Q9R1C1 ENTREZGENE
  Q9R1C3_MOUSE UniProtKB/TrEMBL
UniProt Secondary P97732 UniProtKB/Swiss-Prot
  Q3TU32 UniProtKB/Swiss-Prot
  Q4FJS4 UniProtKB/Swiss-Prot
  Q61397 UniProtKB/Swiss-Prot
  Q76N72 UniProtKB/Swiss-Prot
  Q921P0 UniProtKB/Swiss-Prot
  Q9R1C1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-30 Cd55  CD55 molecule, decay accelerating factor for complement    CD55 antigen  Symbol and/or name change 5135510 APPROVED