Tspo (translocator protein) - Rat Genome Database

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Gene: Tspo (translocator protein) Mus musculus
Analyze
Symbol: Tspo
Name: translocator protein
RGD ID: 10254
MGI Page MGI
Description: Enables transmembrane transporter binding activity. Involved in several processes, including negative regulation of ATP metabolic process; negative regulation of mitophagy; and protein localization to mitochondrion. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; reproductive system; and sensory organ. Orthologous to human TSPO (translocator protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: benzodiazepine receptor, peripheral; Bz; Bzrp; IBP; isoquinoline-binding protein; mitochondrial benzodiazepine receptor; P; PBR; peripheral-type benzodiazepine receptor; PKBS; Ts; Tspo1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,447,774 - 83,458,404 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,447,793 - 83,458,404 (+)EnsemblGRCm39 Ensembl
GRCm381583,563,573 - 83,574,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,563,592 - 83,574,203 (+)EnsemblGRCm38mm10GRCm38
MGSCv371583,394,003 - 83,404,633 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361583,391,377 - 83,401,962 (+)NCBIMGSCv36mm8
Celera1585,689,315 - 85,701,021 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1539.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(1->4)-beta-D-glucan  (EXP)
(S)-nicotine  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-hydroxymidazolam  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
Actein  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
alpha-Zearalanol  (ISO)
alpidem  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (ISO)
atrazine  (ISO)
atropine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bifenthrin  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
carbonyl sulfide  (ISO)
chloropicrin  (ISO)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
cytarabine  (ISO)
diazepam  (EXP)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
ethanol  (ISO)
ezogabine  (ISO)
fenvalerate  (ISO)
flufenacet  (ISO)
flumazenil  (EXP)
flutamide  (ISO)
folic acid  (EXP)
fumonisin B1  (EXP)
furan  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
glafenine  (ISO)
heptachlor  (ISO)
Heptachlor epoxide  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
isobutanol  (ISO)
ivermectin  (ISO)
ketamine  (ISO)
L-ascorbic acid  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
midazolam  (EXP,ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nicotine  (EXP)
oxaliplatin  (ISO)
oxybenzone  (ISO)
p-menthan-3-ol  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
pentachlorophenol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (EXP,ISO)
phosgene  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
PK-11195  (ISO)
porphyrins  (ISO)
procymidone  (ISO)
protoporphyrin  (ISO)
pyrethrins  (ISO)
quinolines  (EXP,ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
sarin  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
tetracycline  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
triadimefon  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP,ISO)
tris(2-chloroethyl) phosphate  (EXP)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tungsten  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vorinostat  (ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (ISO)
behavioral response to pain  (ISO)
cellular hypotonic response  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to zinc ion  (ISO)
chloride transport  (ISO)
cholesterol homeostasis  (ISO)
contact inhibition  (ISO)
establishment of protein localization to mitochondrion  (IMP)
glial cell migration  (ISO)
lipid transport  (IEA)
maintenance of protein location in mitochondrion  (IMP)
monoatomic ion transport  (ISO)
negative regulation of ATP metabolic process  (IMP)
negative regulation of corticosterone secretion  (ISO)
negative regulation of glial cell proliferation  (ISO)
negative regulation of mitophagy  (IMP)
negative regulation of nitric oxide biosynthetic process  (ISO)
negative regulation of protein ubiquitination  (IMP)
negative regulation of tumor necrosis factor production  (ISO)
peripheral nervous system axon regeneration  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of calcium ion transport  (ISO)
positive regulation of glial cell proliferation  (ISO)
positive regulation of mitochondrial depolarization  (ISO)
positive regulation of programmed necrotic cell death  (ISO)
positive regulation of reactive oxygen species metabolic process  (IMP,ISO)
regulation of steroid biosynthetic process  (ISO)
response to acetylcholine  (ISO)
response to axon injury  (ISO)
response to manganese ion  (ISO)
response to pain  (ISO)
response to progesterone  (ISO)
response to testosterone  (ISO)
response to vitamin B1  (ISO)
response to xenobiotic stimulus  (ISO)
steroid biosynthetic process  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Synthesis, delivery and regulation of eukaryotic heme and Fe-S cluster cofactors. Barupala DP, etal., Arch Biochem Biophys. 2016 Feb 15;592:60-75. doi: 10.1016/j.abb.2016.01.010. Epub 2016 Jan 16.
2. An association study between two missense variations of the benzodiazepine receptor (peripheral) gene and schizophrenia in a Japanese sample. Kurumaji A, etal., J Neural Transm 2000;107(4):491-500.
3. Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein. Li H, etal., Mol Endocrinol 2001 Dec;15(12):2211-28.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis. Owen DR, etal., Biochem J. 2017 Nov 21;474(23):3985-3999. doi: 10.1042/BCJ20170648.
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7721091   PMID:8114671   PMID:8125973   PMID:8401507   PMID:8889548   PMID:9226373   PMID:9399693   PMID:10349636   PMID:10591541   PMID:10922068   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:11427320   PMID:11471062   PMID:12466851   PMID:12477932   PMID:12530640   PMID:12769506   PMID:14610273   PMID:14630713   PMID:14651853   PMID:14681479   PMID:15379570  
PMID:15498831   PMID:15528269   PMID:15782199   PMID:15919833   PMID:16104380   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17050526   PMID:17402746   PMID:18287559   PMID:18329265  
PMID:18420025   PMID:18614015   PMID:18991886   PMID:19545604   PMID:19552401   PMID:19729679   PMID:19851043   PMID:20508144   PMID:20814674   PMID:21209087   PMID:21267068   PMID:21299850  
PMID:21677750   PMID:21873635   PMID:22295097   PMID:22378763   PMID:22544055   PMID:22771765   PMID:22874716   PMID:23321458   PMID:24040265   PMID:24174323   PMID:24260329   PMID:24374318  
PMID:24402571   PMID:24599476   PMID:24653034   PMID:24687172   PMID:24692541   PMID:24936060   PMID:25200148   PMID:25406832   PMID:25470454   PMID:25535830   PMID:25818881   PMID:25974690  
PMID:26002041   PMID:26039990   PMID:26123521   PMID:26545928   PMID:26551692   PMID:26551694   PMID:26627829   PMID:26733718   PMID:26741196   PMID:26925573   PMID:26959396   PMID:27063986  
PMID:27265418   PMID:27315802   PMID:27543827   PMID:27626380   PMID:27907096   PMID:28128020   PMID:28189343   PMID:28358007   PMID:28530125   PMID:28640253   PMID:28655607   PMID:28695372  
PMID:29127254   PMID:29300865   PMID:30208620   PMID:30343141   PMID:30385779   PMID:30412797   PMID:31469345   PMID:31530199   PMID:31562844   PMID:31563962   PMID:31879837   PMID:32046185  
PMID:32099945   PMID:32483169   PMID:32561881   PMID:32660586   PMID:32743737   PMID:32839410   PMID:32933996   PMID:32989676   PMID:33158242   PMID:33351449   PMID:33740987   PMID:33941765  
PMID:34321999   PMID:34340010   PMID:34423477   PMID:34685764   PMID:34831289   PMID:34907268   PMID:35177426   PMID:35228700   PMID:35269479   PMID:36060674   PMID:36460205   PMID:36703279  
PMID:36768796   PMID:36787364   PMID:36792609   PMID:36994647   PMID:37294768   PMID:37467699   PMID:37640701   PMID:37891168   PMID:38159656   PMID:38301966   PMID:38355793   PMID:38482552  


Genomics

Comparative Map Data
Tspo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,447,774 - 83,458,404 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,447,793 - 83,458,404 (+)EnsemblGRCm39 Ensembl
GRCm381583,563,573 - 83,574,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,563,592 - 83,574,203 (+)EnsemblGRCm38mm10GRCm38
MGSCv371583,394,003 - 83,404,633 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361583,391,377 - 83,401,962 (+)NCBIMGSCv36mm8
Celera1585,689,315 - 85,701,021 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1539.4NCBI
TSPO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382243,151,559 - 43,163,242 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2243,151,547 - 43,163,242 (+)EnsemblGRCh38hg38GRCh38
GRCh372243,547,565 - 43,559,248 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,877,479 - 41,889,192 (+)NCBINCBI36Build 36hg18NCBI36
Build 342241,872,050 - 41,883,745NCBI
Celera2227,457,910 - 27,469,623 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2226,505,727 - 26,517,455 (+)NCBIHuRef
CHM1_12243,507,104 - 43,518,509 (+)NCBICHM1_1
T2T-CHM13v2.02243,632,715 - 43,644,077 (+)NCBIT2T-CHM13v2.0
Tspo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,600,214 - 116,610,461 (+)NCBIGRCr8
mRatBN7.27114,720,188 - 114,730,450 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7114,720,188 - 114,730,450 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7116,467,236 - 116,477,482 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07118,693,096 - 118,703,201 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07118,662,565 - 118,672,671 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07124,460,358 - 124,470,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,460,358 - 124,470,609 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07124,449,361 - 124,459,090 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,597,084 - 121,599,342 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17121,631,313 - 121,633,572 (+)NCBI
Celera7111,031,561 - 111,041,788 (+)NCBICelera
RH 3.4 Map7906.4RGD
Cytogenetic Map7q34NCBI
Tspo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541328,308,658 - 28,315,075 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541328,309,105 - 28,315,075 (+)NCBIChiLan1.0ChiLan1.0
TSPO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22352,974,420 - 52,985,872 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12255,667,318 - 55,678,778 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02224,034,918 - 24,046,370 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12242,233,186 - 42,244,930 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2242,233,619 - 42,244,930 (+)Ensemblpanpan1.1panPan2
TSPO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11022,388,498 - 22,399,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1022,274,405 - 22,399,297 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1022,325,190 - 22,336,049 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01023,132,949 - 23,143,978 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1023,132,954 - 23,135,891 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11022,852,287 - 22,863,109 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01023,171,467 - 23,182,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01023,347,120 - 23,357,948 (-)NCBIUU_Cfam_GSD_1.0
Tspo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049455,984,991 - 5,987,864 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936718992,301 - 995,995 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936718992,301 - 995,172 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl55,723,190 - 5,735,131 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.155,723,190 - 5,735,097 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.253,145,792 - 3,157,669 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TSPO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11925,678,602 - 25,690,556 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1925,686,981 - 25,690,768 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604599,748,097 - 99,760,895 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspo
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247525,814,784 - 5,820,141 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247525,814,784 - 5,820,250 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tspo
283 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:151
Count of miRNA genes:141
Interacting mature miRNAs:147
Transcripts:ENSMUST00000047419
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
11532732Pitm5_mprion incubation time 5 (mouse)158296406187054388Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse

Markers in Region
Bzrp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS
Tspo  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381583,571,518 - 83,572,242UniSTSGRCm38
MGSCv371583,401,948 - 83,402,672UniSTSGRCm37
Celera1585,698,379 - 85,699,103UniSTS
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS
Tspo  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15E1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA472650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI841615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL583887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY079441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY079442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L17306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U12419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000047419   ⟹   ENSMUSP00000037039
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,447,793 - 83,458,404 (+)Ensembl
GRCm38.p6 Ensembl1583,563,592 - 83,574,203 (+)Ensembl
Ensembl Acc Id: ENSMUST00000208463   ⟹   ENSMUSP00000146965
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,448,076 - 83,456,526 (+)Ensembl
GRCm38.p6 Ensembl1583,563,875 - 83,572,325 (+)Ensembl
RefSeq Acc Id: NM_009775   ⟹   NP_033905
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391583,447,774 - 83,458,404 (+)NCBI
GRCm381583,563,573 - 83,574,203 (+)NCBI
MGSCv371583,394,003 - 83,404,633 (+)RGD
Celera1585,689,315 - 85,701,021 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033905   ⟸   NM_009775
- UniProtKB: Q6LCZ0 (UniProtKB/Swiss-Prot),   Q62118 (UniProtKB/Swiss-Prot),   Q541E3 (UniProtKB/Swiss-Prot),   Q99M32 (UniProtKB/Swiss-Prot),   P50637 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000037039   ⟸   ENSMUST00000047419
Ensembl Acc Id: ENSMUSP00000146965   ⟸   ENSMUST00000208463

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50637-F1-model_v2 AlphaFold P50637 1-169 view protein structure

Promoters
RGD ID:6826575
Promoter ID:MM_KWN:19257
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_009775
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361583,393,396 - 83,394,362 (+)MPROMDB
RGD ID:8684574
Promoter ID:EPDNEW_M20318
Type:initiation region
Name:Tspo_1
Description:Mus musculus translocator protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381583,563,599 - 83,563,659EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88222 AgrOrtholog
Ensembl Genes ENSMUSG00000041736 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047419 ENTREZGENE
  ENSMUST00000047419.8 UniProtKB/Swiss-Prot
  ENSMUST00000208463.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1260.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TspO/MBR-related_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TspO_MBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12257 UniProtKB/Swiss-Prot
MGD MGI:88222 ENTREZGENE
NCBI Gene 12257 ENTREZGENE
PANTHER PTHR10057 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10057:SF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TspO_MBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB TSPO RGD
PhenoGen Tspo PhenoGen
PIRSF PBR UniProtKB/Swiss-Prot
UniProt A0A140LIU9_MOUSE UniProtKB/TrEMBL
  P50637 ENTREZGENE
  Q541E3 ENTREZGENE
  Q62118 ENTREZGENE
  Q6LCZ0 ENTREZGENE
  Q99M32 ENTREZGENE
  TSPO_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q541E3 UniProtKB/Swiss-Prot
  Q62118 UniProtKB/Swiss-Prot
  Q6LCZ0 UniProtKB/Swiss-Prot
  Q99M32 UniProtKB/Swiss-Prot