(+)-pilocarpine decreases expression ISO RGD:2213 6480464 Pilocarpine results in decreased expression of BMP4 mRNA CTD PMID:17971868 (+)-pilocarpine increases expression ISO RGD:2213 6480464 Pilocarpine results in increased expression of BMP4 mRNA CTD PMID:17971868 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:730832 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of BMP4 mRNA CTD PMID:22079256 (S)-amphetamine multiple interactions EXP 6480464 SOD1 inhibits the reaction [Dextroamphetamine results in decreased expression of BMP4 mRNA] CTD PMID:12205029 (S)-amphetamine decreases expression EXP 6480464 Dextroamphetamine results in decreased expression of BMP4 mRNA CTD PMID:12205029 (S)-nicotine decreases expression ISO RGD:2213 6480464 Nicotine results in decreased expression of BMP4 mRNA CTD PMID:20339300 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane increases expression ISO RGD:2213 6480464 2, 2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of BMP4 mRNA CTD PMID:15991191 1,2-dimethylhydrazine increases expression EXP 6480464 1, 2-Dimethylhydrazine results in increased expression of BMP4 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of BMP4 mRNA] CTD PMID:22206623 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine increases expression ISO RGD:2213 6480464 chlorcyclizine results in increased expression of BMP4 mRNA CTD PMID:21058326 17alpha-ethynylestradiol decreases expression ISO RGD:2213 6480464 Ethinyl Estradiol results in decreased expression of BMP4 mRNA CTD PMID:16551644 17beta-estradiol affects expression ISO RGD:730832 6480464 Estradiol affects the expression of BMP4 mRNA CTD PMID:14699072 , PMID:22574217 17beta-estradiol decreases expression ISO RGD:730832 6480464 Estradiol results in decreased expression of BMP4 mRNA CTD PMID:26921789 17beta-estradiol multiple interactions ISO RGD:2213 6480464 [BMP4 protein results in increased expression of CYP19A1 mRNA] promotes the reaction [FSHB protein results in increased abundance of Estradiol], BMP4 protein inhibits the reaction [IGF1 protein promotes the reaction [FSHB protein results in increased abundance of Estradiol]] CTD PMID:22067323 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of BMP4 mRNA CTD PMID:23144751 17beta-estradiol multiple interactions ISO RGD:730832 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of BMP4 mRNA CTD PMID:20404318 2,3,7,8-tetrachlorodibenzodioxine decreases secretion EXP 6480464 Tetrachlorodibenzodioxin results in decreased secretion of BMP4 protein CTD PMID:26572662 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of BMP4 mRNA CTD PMID:18691609 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:730832 6480464 Tetrachlorodibenzodioxin results in increased expression of BMP4 mRNA CTD PMID:19684285 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of BMP4 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of BMP4 mRNA CTD PMID:16054899 , PMID:17586704 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of BMP4 mRNA CTD PMID:16054899 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:730832 6480464 Tetrachlorodibenzodioxin results in decreased expression of BMP4 mRNA CTD PMID:19684285 2-amino-2-deoxy-D-glucopyranose decreases expression ISO RGD:2213 6480464 Glucosamine results in decreased expression of BMP4 mRNA CTD PMID:17109745 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:2213 6480464 Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] CTD PMID:17109745 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:2213 6480464 3 more ... CTD PMID:23196670 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of BMP4 mRNA CTD PMID:25172293 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of BMP4 mRNA CTD PMID:16054899 3-methylcholanthrene decreases expression ISO RGD:2213 6480464 Methylcholanthrene results in decreased expression of BMP4 mRNA CTD PMID:29094188 4,4'-sulfonyldiphenol increases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of BMP4 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of BMP4 mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of BMP4 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of BMP4 mRNA CTD PMID:27915011 8-Br-cAMP decreases expression ISO RGD:730832 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of BMP4 mRNA CTD PMID:22079614 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of BMP4 mRNA CTD PMID:29261810 aldehydo-D-glucosamine decreases expression ISO RGD:2213 6480464 Glucosamine results in decreased expression of BMP4 mRNA CTD PMID:17109745 aldehydo-D-glucosamine multiple interactions ISO RGD:2213 6480464 Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] CTD PMID:17109745 all-trans-retinoic acid multiple interactions ISO RGD:730832 6480464 [Tretinoin co-treated with BMP4 protein] results in increased expression of KRT18 protein more ... CTD PMID:15268896 , PMID:30397335 all-trans-retinoic acid affects expression ISO RGD:730832 6480464 Tretinoin affects the expression of BMP4 mRNA CTD PMID:31600526 all-trans-retinoic acid multiple interactions EXP 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of BMP4 mRNA more ... CTD PMID:30951980 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of BMP4 mRNA, Tretinoin results in increased expression of BMP4 protein CTD PMID:16195406 , PMID:18703560 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of BMP4 mRNA CTD PMID:15996115 , PMID:16604517 all-trans-retinoic acid decreases activity EXP 6480464 Tretinoin results in decreased activity of BMP4 protein CTD PMID:16818722 all-trans-retinoic acid affects expression EXP 6480464 Tretinoin affects the expression of BMP4 CTD PMID:10862743 all-trans-retinoic acid increases expression ISO RGD:730832 6480464 Tretinoin results in increased expression of BMP4 mRNA CTD PMID:17196394 all-trans-retinol affects expression EXP 6480464 Vitamin A affects the expression of BMP4 mRNA CTD PMID:16120438 aluminium oxide increases expression ISO RGD:730832 6480464 Aluminum Oxide results in increased expression of BMP4 mRNA CTD PMID:19464052 ammonium chloride affects expression ISO RGD:2213 6480464 Ammonium Chloride affects the expression of BMP4 mRNA CTD PMID:16483693 antimonite multiple interactions ISO RGD:730832 6480464 RTKI cpd inhibits the reaction [antimonite results in decreased expression of BMP4 mRNA] CTD PMID:17400267 antimonite decreases expression ISO RGD:730832 6480464 antimonite results in decreased expression of BMP4 mRNA CTD PMID:17400267 arsane increases expression ISO RGD:730832 6480464 Arsenic results in increased expression of BMP4 mRNA CTD PMID:12773770 arsane multiple interactions ISO RGD:730832 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of BMP4 mRNA CTD PMID:32525701 arsenic atom increases expression ISO RGD:730832 6480464 Arsenic results in increased expression of BMP4 mRNA CTD PMID:12773770 arsenic atom multiple interactions ISO RGD:730832 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of BMP4 mRNA CTD PMID:32525701 arsenite(3-) decreases expression ISO RGD:730832 6480464 arsenite results in decreased expression of BMP4 mRNA CTD PMID:17400267 arsenite(3-) multiple interactions ISO RGD:730832 6480464 RTKI cpd inhibits the reaction [arsenite results in decreased expression of BMP4 mRNA] CTD PMID:17400267 bacitracin decreases expression ISO RGD:2213 6480464 Bacitracin results in decreased expression of BMP4 mRNA CTD PMID:18289764 benzo[a]pyrene increases expression ISO RGD:2213 6480464 Benzo(a)pyrene results in increased expression of BMP4 mRNA CTD PMID:21839799 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of BMP4 mRNA CTD PMID:22228805 beta-D-glucosamine decreases expression ISO RGD:2213 6480464 Glucosamine results in decreased expression of BMP4 mRNA CTD PMID:17109745 beta-D-glucosamine multiple interactions ISO RGD:2213 6480464 Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] CTD PMID:17109745 bis(2-ethylhexyl) phthalate increases expression ISO RGD:2213 6480464 Diethylhexyl Phthalate results in increased expression of BMP4 mRNA CTD PMID:22677342 bisphenol A decreases expression ISO RGD:2213 6480464 bisphenol A results in decreased expression of BMP4 mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of BMP4 mRNA CTD PMID:30951980 bisphenol A affects expression ISO RGD:730832 6480464 bisphenol A affects the expression of BMP4 mRNA CTD PMID:30903817 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of BMP4 mRNA CTD PMID:30951980 bisphenol A decreases expression ISO RGD:730832 6480464 bisphenol A results in decreased expression of BMP4 mRNA CTD PMID:27685785 bisphenol F multiple interactions EXP 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of BMP4 mRNA CTD PMID:30951980 bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of BMP4 mRNA CTD PMID:30951980 bucladesine multiple interactions ISO RGD:730832 6480464 Bucladesine inhibits the reaction [BMP4 protein results in increased expression of SMAD6 mRNA] CTD PMID:20522807 busulfan decreases expression ISO RGD:2213 6480464 Busulfan results in decreased expression of BMP4 mRNA CTD PMID:15786497 cadmium dichloride multiple interactions ISO RGD:730832 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of BMP4 mRNA CTD PMID:12634122 cadmium dichloride increases expression ISO RGD:2213 6480464 Cadmium Chloride results in increased expression of BMP4 mRNA CTD PMID:21297351 calcitriol multiple interactions ISO RGD:730832 6480464 Calcitriol promotes the reaction [BMP4 protein results in increased expression of SOST mRNA] CTD PMID:15268896 calcium atom affects expression ISO RGD:2213 6480464 Calcium affects the expression of BMP4 mRNA CTD PMID:15913539 calcium atom multiple interactions ISO RGD:730832 6480464 [Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein, [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein] CTD PMID:18369157 calcium(0) affects expression ISO RGD:2213 6480464 Calcium affects the expression of BMP4 mRNA CTD PMID:15913539 calcium(0) multiple interactions ISO RGD:730832 6480464 [Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein, [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein] CTD PMID:18369157 carbamazepine affects expression ISO RGD:730832 6480464 Carbamazepine affects the expression of BMP4 mRNA CTD PMID:24752500 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of BMP4 mRNA, Nanotubes, Carbon results in decreased expression of BMP4 mRNA CTD PMID:25554681 casticin increases expression ISO RGD:730832 6480464 casticin results in increased expression of BMP4 mRNA CTD PMID:27862857 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BMP4 gene CTD PMID:20938992 chromium(6+) decreases expression ISO RGD:730832 6480464 chromium hexavalent ion results in decreased expression of BMP4 mRNA CTD PMID:30690063 cisplatin increases expression ISO RGD:730832 6480464 Cisplatin results in increased expression of BMP4 mRNA CTD PMID:21674241 cobalt dichloride decreases expression ISO RGD:730832 6480464 cobaltous chloride results in decreased expression of BMP4 mRNA CTD PMID:19320972 copper atom decreases expression ISO RGD:2213 6480464 Copper results in decreased expression of BMP4 mRNA CTD PMID:22465980 copper(0) decreases expression ISO RGD:2213 6480464 Copper results in decreased expression of BMP4 mRNA CTD PMID:22465980 cyclosporin A decreases expression ISO RGD:2213 6480464 Cyclosporine results in decreased expression of BMP4 mRNA CTD PMID:21865292 cyclosporin A decreases expression ISO RGD:730832 6480464 Cyclosporine results in decreased expression of BMP4 mRNA CTD PMID:25562108 , PMID:27989131 cytarabine decreases expression ISO RGD:730832 6480464 Cytarabine results in decreased expression of BMP4 mRNA CTD PMID:21198554 dexamethasone multiple interactions ISO RGD:730832 6480464 Dexamethasone inhibits the reaction [BMP4 protein results in increased expression of GREM1 mRNA], Dexamethasone inhibits the reaction [BMP4 protein results in increased expression of SOST mRNA] CTD PMID:15268896 dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of BMP4 mRNA CTD PMID:16054899 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of BMP4 mRNA CTD PMID:21277400 dibutyl phthalate increases expression ISO RGD:2213 6480464 Dibutyl Phthalate results in increased expression of BMP4 mRNA CTD PMID:15829613 dibutyl phthalate decreases expression ISO RGD:2213 6480464 Dibutyl Phthalate results in decreased expression of BMP4 mRNA, Dibutyl Phthalate results in decreased expression of BMP4 protein CTD PMID:19464577 more ... dichlorine multiple interactions ISO RGD:2213 6480464 [Ozone co-treated with Chlorine] results in increased expression of BMP4 mRNA CTD PMID:18636392 dichromium trioxide multiple interactions ISO RGD:730832 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of BMP4 mRNA CTD PMID:12634122 diclofenac affects expression ISO RGD:730832 6480464 Diclofenac affects the expression of BMP4 mRNA CTD PMID:24752500 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of BMP4 mRNA, [sulforafan affects the susceptibility to Oxygen] which affects the expression of BMP4 mRNA CTD PMID:30529165 disodium selenite multiple interactions EXP 6480464 [ptaquiloside co-treated with Sodium Selenite] results in decreased expression of BMP4 mRNA CTD PMID:23274088 disodium selenite decreases expression ISO RGD:730832 6480464 Sodium Selenite results in decreased expression of BMP4 mRNA CTD PMID:24383545 disodium selenite decreases expression EXP 6480464 Sodium Selenite results in decreased expression of BMP4 mRNA CTD PMID:23274088 dorsomorphin multiple interactions ISO RGD:730832 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of BMP4 protein CTD PMID:17415656 doxorubicin decreases expression ISO RGD:730832 6480464 Doxorubicin results in decreased expression of BMP4 mRNA CTD PMID:23956100 , PMID:29803840 endosulfan decreases expression ISO RGD:2213 6480464 Endosulfan results in decreased expression of BMP4 mRNA CTD PMID:29391264 ethylenediaminetetraacetic acid multiple interactions ISO RGD:730832 6480464 [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein] CTD PMID:18369157 Ethylenethiourea decreases expression ISO RGD:2213 6480464 Ethylenethiourea results in decreased expression of BMP4 mRNA CTD PMID:17161201 , PMID:18082712 flavonoids increases expression ISO RGD:2213 6480464 Flavonoids results in increased expression of BMP4 mRNA CTD PMID:18035473 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BMP4 gene more ... CTD PMID:20938992 , PMID:22206623 furan increases expression ISO RGD:2213 6480464 furan results in increased expression of BMP4 mRNA CTD PMID:27387713 furan decreases methylation ISO RGD:2213 6480464 furan results in decreased methylation of BMP4 gene CTD PMID:27387713 genistein increases expression EXP 6480464 Genistein results in increased expression of BMP4 mRNA CTD PMID:16169203 glycidol decreases expression ISO RGD:2213 6480464 glycidol results in decreased expression of BMP4 mRNA CTD PMID:24915197 hydrogen peroxide decreases expression ISO RGD:730832 6480464 Hydrogen Peroxide results in decreased expression of BMP4 mRNA CTD PMID:12419474 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of BMP4 mRNA CTD PMID:23562911 icariin increases expression ISO RGD:2213 6480464 icariin results in increased expression of BMP4 mRNA CTD PMID:20019778 icariin increases expression EXP 6480464 icariin results in increased expression of BMP4 mRNA CTD PMID:18295595 iloprost multiple interactions ISO RGD:730832 6480464 Iloprost inhibits the reaction [BMP4 protein results in increased expression of SMAD6 mRNA] more ... CTD PMID:20522807 indole-3-methanol affects expression ISO RGD:2213 6480464 indole-3-carbinol affects the expression of BMP4 mRNA CTD PMID:21396975 kaempferol increases expression EXP 6480464 kaempferol results in increased expression of BMP4 mRNA CTD PMID:23989061 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BMP4 gene CTD PMID:20938992 lead diacetate multiple interactions ISO RGD:730832 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of BMP4 mRNA CTD PMID:12634122 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of BMP4 mRNA CTD PMID:22613225 linuron decreases expression ISO RGD:2213 6480464 Linuron results in decreased expression of BMP4 mRNA CTD PMID:12730624 lithium chloride increases expression ISO RGD:730832 6480464 Lithium Chloride results in increased expression of BMP4 mRNA CTD PMID:15711924 maneb multiple interactions EXP 6480464 [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA, [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA CTD PMID:23017109 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of BMP4 mRNA CTD PMID:17467022 mercury dibromide increases expression ISO RGD:730832 6480464 mercuric bromide results in increased expression of BMP4 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:730832 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP4 mRNA CTD PMID:27188386 methotrexate affects expression EXP 6480464 Methotrexate affects the expression of BMP4 mRNA CTD PMID:18502557 methotrexate decreases response to substance ISO RGD:730832 6480464 BMP4 mRNA results in decreased susceptibility to Methotrexate CTD PMID:20008919 methylmercury chloride decreases expression ISO RGD:730832 6480464 methylmercuric chloride results in decreased expression of BMP4 mRNA CTD PMID:23179753 methylmercury chloride increases expression ISO RGD:730832 6480464 methylmercuric chloride results in increased expression of BMP4 mRNA CTD PMID:28001369 methylseleninic acid increases expression ISO RGD:730832 6480464 methylselenic acid results in increased expression of BMP4 mRNA CTD PMID:12517777 mitomycin C decreases expression ISO RGD:730832 6480464 Mitomycin results in decreased expression of BMP4 mRNA CTD PMID:12760830 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO RGD:730832 6480464 Methylnitronitrosoguanidine results in decreased expression of BMP4 mRNA CTD PMID:12773770 naringin increases expression ISO RGD:730832 6480464 naringin results in increased expression of BMP4 mRNA CTD PMID:24915843 nickel sulfate increases expression ISO RGD:730832 6480464 nickel sulfate results in increased expression of BMP4 mRNA CTD PMID:22714537 nicotine decreases expression ISO RGD:2213 6480464 Nicotine results in decreased expression of BMP4 mRNA CTD PMID:20339300 nitrates decreases expression ISO RGD:2213 6480464 Nitrates results in decreased expression of BMP4 mRNA CTD PMID:30022042 nitrofen decreases expression ISO RGD:2213 6480464 nitrofen results in decreased expression of BMP4 mRNA CTD PMID:17270562 , PMID:18280291 ochratoxin A increases acetylation ISO RGD:730832 6480464 ochratoxin A results in increased acetylation of BMP4 promoter CTD PMID:29098329 ochratoxin A multiple interactions ISO RGD:730832 6480464 [ochratoxin A results in increased acetylation of BMP4 promoter] which results in increased expression of BMP4 mRNA CTD PMID:29098329 ochratoxin A increases expression ISO RGD:730832 6480464 ochratoxin A results in increased expression of BMP4 mRNA CTD PMID:29098329 octreotide multiple interactions ISO RGD:730832 6480464 Octreotide promotes the reaction [BMP4 protein results in increased expression of ID1 mRNA] CTD PMID:23137853 orphenadrine affects expression ISO RGD:2213 6480464 Orphenadrine affects the expression of BMP4 mRNA CTD PMID:23665939 oxaliplatin increases expression ISO RGD:2213 6480464 oxaliplatin results in increased expression of BMP4 mRNA CTD PMID:25729387 oxaliplatin multiple interactions ISO RGD:2213 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of BMP4 mRNA CTD PMID:25729387 ozone multiple interactions ISO RGD:2213 6480464 [Ozone co-treated with Chlorine] results in increased expression of BMP4 mRNA CTD PMID:18636392 paclitaxel decreases expression ISO RGD:730832 6480464 Paclitaxel results in decreased expression of BMP4 mRNA CTD PMID:23956100 panobinostat multiple interactions ISO RGD:730832 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP4 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:730832 6480464 panobinostat results in increased expression of BMP4 mRNA CTD PMID:26272509 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of BMP4 mRNA CTD PMID:17562736 paraquat multiple interactions EXP 6480464 [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA, [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA CTD PMID:23017109 paraquat decreases expression ISO RGD:2213 6480464 Paraquat results in decreased expression of BMP4 mRNA CTD PMID:18198484 paricalcitol multiple interactions ISO RGD:730832 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of BMP4 mRNA CTD PMID:17715259 pasireotide multiple interactions ISO RGD:730832 6480464 pasireotide promotes the reaction [BMP4 protein results in increased expression of ID1 mRNA] CTD PMID:23137853 perfluorononanoic acid decreases expression ISO RGD:730832 6480464 perfluorononanoic acid results in decreased expression of BMP4 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of BMP4 mRNA CTD PMID:23562911 phenylmercury acetate increases expression ISO RGD:730832 6480464 Phenylmercuric Acetate results in increased expression of BMP4 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:730832 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP4 mRNA CTD PMID:27188386 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of BMP4 mRNA CTD PMID:16141649 phosphorus atom multiple interactions ISO RGD:730832 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of BMP4 mRNA CTD PMID:17715259 phosphorus(.) multiple interactions ISO RGD:730832 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of BMP4 mRNA CTD PMID:17715259 pinosylvin multiple interactions ISO RGD:730832 6480464 [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA CTD PMID:23333577 potassium chromate decreases expression ISO RGD:730832 6480464 potassium chromate(VI) results in decreased expression of BMP4 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:730832 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of BMP4 mRNA CTD PMID:22079256 progesterone multiple interactions ISO RGD:2213 6480464 [BMP4 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone] more ... CTD PMID:22067323 Ptaquiloside multiple interactions EXP 6480464 [ptaquiloside co-treated with Sodium Selenite] results in decreased expression of BMP4 mRNA CTD PMID:23274088 quercetin decreases expression ISO RGD:730832 6480464 Quercetin results in decreased expression of BMP4 mRNA CTD PMID:21632981 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [BMP4 protein results in increased expression of VEGFA mRNA], Resveratrol inhibits the reaction [BMP4 protein results in increased secretion of VEGFA protein] CTD PMID:24435444 resveratrol increases expression ISO RGD:730832 6480464 resveratrol results in increased expression of BMP4 mRNA CTD PMID:25888808 retinyl acetate increases expression EXP 6480464 retinol acetate results in increased expression of BMP4 mRNA CTD PMID:16772331 rifampicin multiple interactions ISO RGD:730832 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA CTD PMID:21127053 rotenone decreases expression ISO RGD:730832 6480464 Rotenone results in decreased expression of BMP4 mRNA CTD PMID:29955902 SB 431542 multiple interactions ISO RGD:730832 6480464 [4-(5-benzo(1 more ... CTD PMID:25670856 , PMID:27188386 silicon dioxide decreases expression ISO RGD:730832 6480464 Silicon Dioxide analog results in decreased expression of BMP4 mRNA, Silicon Dioxide results in decreased expression of BMP4 mRNA CTD PMID:25895662 , PMID:28425640 silver atom increases expression EXP 6480464 Silver results in increased expression of BMP4 mRNA CTD PMID:27131904 silver atom decreases expression ISO RGD:730832 6480464 Silver results in decreased expression of BMP4 mRNA CTD PMID:26014281 silver(0) increases expression EXP 6480464 Silver results in increased expression of BMP4 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:730832 6480464 Silver results in decreased expression of BMP4 mRNA CTD PMID:26014281 sodium arsenate multiple interactions ISO RGD:730832 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of BMP4 mRNA CTD PMID:32525701 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of BMP4 mRNA CTD PMID:16014739 sodium arsenite increases expression ISO RGD:730832 6480464 sodium arsenite results in increased expression of BMP4 mRNA CTD PMID:12634122 more ... sodium arsenite multiple interactions ISO RGD:730832 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of BMP4 mRNA CTD PMID:12634122 sodium arsenite decreases expression ISO RGD:730832 6480464 sodium arsenite results in decreased expression of BMP4 mRNA CTD PMID:19615344 sodium chlorate decreases expression ISO RGD:2213 6480464 sodium chlorate results in decreased expression of BMP4 mRNA CTD PMID:12922982 sodium dichromate decreases expression ISO RGD:730832 6480464 sodium bichromate results in decreased expression of BMP4 mRNA CTD PMID:12760830 sulforaphane multiple interactions EXP 6480464 [sulforafan affects the susceptibility to Oxygen] which affects the expression of BMP4 mRNA CTD PMID:30529165 tert-butyl hydroperoxide decreases expression ISO RGD:730832 6480464 tert-Butylhydroperoxide results in decreased expression of BMP4 mRNA CTD PMID:12419474 testosterone affects expression EXP 6480464 Testosterone affects the expression of BMP4 mRNA CTD PMID:20403060 testosterone decreases expression EXP 6480464 Testosterone results in decreased expression of BMP4 mRNA CTD PMID:22138414 topotecan multiple interactions ISO RGD:2213 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of BMP4 mRNA CTD PMID:25729387 topotecan increases expression ISO RGD:2213 6480464 Topotecan results in increased expression of BMP4 mRNA CTD PMID:25729387 trans-pinosylvin multiple interactions ISO RGD:730832 6480464 [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA CTD PMID:23333577 trichostatin A increases expression ISO RGD:2213 6480464 trichostatin A results in increased expression of BMP4 mRNA CTD PMID:23562654 trichostatin A multiple interactions ISO RGD:730832 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP4 mRNA CTD PMID:27188386 trichostatin A increases expression ISO RGD:730832 6480464 trichostatin A results in increased expression of BMP4 mRNA CTD PMID:24935251 , PMID:26272509 tyrphostin AG 1478 multiple interactions ISO RGD:730832 6480464 RTKI cpd inhibits the reaction [antimonite results in decreased expression of BMP4 mRNA], RTKI cpd inhibits the reaction [arsenite results in decreased expression of BMP4 mRNA] CTD PMID:17400267 urethane multiple interactions EXP 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of BMP4 mRNA CTD PMID:12400877 urethane decreases expression ISO RGD:730832 6480464 Urethane results in decreased expression of BMP4 mRNA CTD PMID:28818685 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of BMP4 mRNA CTD PMID:19136453 valproic acid multiple interactions ISO RGD:730832 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP4 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:730832 6480464 Valproic Acid results in increased expression of BMP4 mRNA CTD PMID:23179753 more ... valproic acid increases expression ISO RGD:2213 6480464 Valproic Acid results in increased expression of BMP4 mRNA CTD PMID:23562654 , PMID:29427782 valsartan multiple interactions ISO RGD:730832 6480464 Valsartan inhibits the reaction [AGT protein results in decreased expression of BMP4 mRNA] CTD PMID:19225232 vinclozolin affects expression ISO RGD:2213 6480464 vinclozolin affects the expression of BMP4 mRNA CTD PMID:19015723 vitamin E increases expression ISO RGD:730832 6480464 Vitamin E results in increased expression of BMP4 mRNA CTD PMID:19244175 vorinostat increases expression ISO RGD:730832 6480464 vorinostat results in increased expression of BMP4 mRNA CTD PMID:26272509
Biological Process activation of MAPKK activity ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 anatomical structure formation involved in morphogenesis IGI MGI:MGI:104327 2290270 (MGI:MGI:3654583, PMID:16916379) MGI MGI:MGI:3654583 , PMID:16916379 anatomical structure regression ISO RGD:2213 9068941 RGD PMID:12808102 , REF_RGD_ID:8998993 angiogenesis IMP MGI:MGI:3042751 2290270 (MGI:MGI:3039210, PMID:15070745) MGI MGI:MGI:3039210 , PMID:15070745 anterior/posterior axis specification IGI MGI:MGI:104903 2290270 (MGI:MGI:1889107, PMID:10964473) MGI MGI:MGI:1889107 , PMID:10964473 aortic valve morphogenesis IMP 2290270 (MGI:MGI:3039210 more ... BHF-UCL MGI:MGI:3039210 more ... apoptotic process involved in endocardial cushion morphogenesis NOT IMP 2290270 (MGI:MGI:3814273, PMID:18924235) BHF-UCL MGI:MGI:3814273 , PMID:18924235 blood vessel development IDA 2290270 (MGI:MGI:48668, PMID:1521591) MGI MGI:MGI:48668 , PMID:1521591 blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 BMP signaling pathway IGI MGI:MGI:2679262 2290270 (MGI:MGI:3590430, PMID:15975920) MGI MGI:MGI:3590430 , PMID:15975920 BMP signaling pathway IDA 2290270 (MGI:MGI:2681048 more ... MGI MGI:MGI:2681048 more ... BMP signaling pathway ISO UniProtKB:P12644 2290270 (MGI:MGI:3718174, PMID:17472960) MGI GO_REF:0000096 more ... BMP signaling pathway involved in heart development IMP 2290270 (MGI:MGI:3039210, PMID:15070745) BHF-UCL MGI:MGI:3039210 , PMID:15070745 BMP signaling pathway involved in heart induction ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 BMP signaling pathway involved in nephric duct formation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 BMP signaling pathway involved in renal system segmentation IMP 2290270 (MGI:MGI:3710018, PMID:17442697) UniProtKB MGI:MGI:3710018 , PMID:17442697 BMP signaling pathway involved in ureter morphogenesis IDA 2290270 (MGI:MGI:3710018, PMID:17442697) UniProtKB MGI:MGI:3710018 , PMID:17442697 bone development IDA 2290270 (MGI:MGI:63654, PMID:8358941) MGI MGI:MGI:63654 , PMID:8358941 brain development ISO RGD:2213 9068941 RGD PMID:14643011 , REF_RGD_ID:1358324 branching involved in prostate gland morphogenesis IMP MGI:MGI:1857137 2290270 (MGI:MGI:1934513, PMID:11401393) MGI MGI:MGI:1934513 , PMID:11401393 branching involved in ureteric bud morphogenesis IGI MGI:MGI:1344337 2290270 (MGI:MGI:3714585, PMID:17522159) MGI MGI:MGI:3714585 , PMID:17522159 branching involved in ureteric bud morphogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 branching morphogenesis of an epithelial tube ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 bronchus development ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 bud dilation involved in lung branching ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 bud elongation involved in lung branching IDA 2290270 (MGI:MGI:3788965, PMID:18367557) MGI MGI:MGI:3788965 , PMID:18367557 camera-type eye development IMP MGI:MGI:1857137 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 camera-type eye development IGI MGI:MGI:2137520 2290270 (MGI:MGI:3043486, PMID:14681194) MGI MGI:MGI:3043486 , PMID:14681194 camera-type eye morphogenesis IMP MGI:MGI:88180 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 cardiac jelly development NOT IMP 2290270 (MGI:MGI:3814273, PMID:18924235) BHF-UCL MGI:MGI:3814273 , PMID:18924235 cardiac muscle cell differentiation IGI UniProtKB:P21274 2290270 (MGI:MGI:4939577, PMID:21145505) BHF-UCL MGI:MGI:4939577 , PMID:21145505 cardiac muscle cell differentiation NAS 2290270 (MGI:MGI:5142394, PMID:9857019) UniProtKB MGI:MGI:5142394 , PMID:9857019 cardiac right ventricle morphogenesis NOT IMP 2290270 (MGI:MGI:3814273, PMID:18924235) BHF-UCL MGI:MGI:3814273 , PMID:18924235 cartilage development IEA UniProtKB-KW:KW-0891 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 cell differentiation IEA UniProtKB-KW:KW-0221 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 cell fate commitment IDA 2290270 (MGI:MGI:2429473, PMID:12421925) MGI MGI:MGI:2429473 , PMID:12421925 cellular response to BMP stimulus ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 cellular response to dexamethasone stimulus ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 cellular response to growth factor stimulus IDA 2290270 (MGI:MGI:69105, PMID:7848824) MGI MGI:MGI:69105 , PMID:7848824 cellular response to mechanical stimulus ISO RGD:2213 9068941 RGD PMID:20877159 , REF_RGD_ID:9068439 cellular response to oxidative stress ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 cellular response to thyroid hormone stimulus ISO RGD:2213 9068941 RGD PMID:12395077 , REF_RGD_ID:9068403 chondrocyte differentiation IMP 2290270 (MGI:MGI:4418577, PMID:20059955) UniProtKB MGI:MGI:4418577 , PMID:20059955 cloacal septation IEP 2290270 (PMID:17442697) UniProtKB PMID:17442697 common-partner SMAD protein phosphorylation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 coronary vasculature development IMP 2290270 (MGI:MGI:3039210, PMID:15070745) BHF-UCL MGI:MGI:3039210 , PMID:15070745 cranial suture morphogenesis IDA 2290270 (MGI:MGI:1203304, PMID:9477322) MGI MGI:MGI:1203304 , PMID:9477322 deltoid tuberosity development IMP 2290270 (MGI:MGI:4418577, PMID:20059955) UniProtKB MGI:MGI:4418577 , PMID:20059955 dorsal/ventral neural tube patterning IDA 2290270 (MGI:MGI:3046395, PMID:15218525) MGI MGI:MGI:3046395 , PMID:15218525 embryonic cranial skeleton morphogenesis IMP MGI:MGI:1857137 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 embryonic digit morphogenesis IGI MGI:MGI:108359 , MGI:MGI:95729 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 embryonic hindlimb morphogenesis IGI MGI:MGI:104903 2290270 (MGI:MGI:1889107, PMID:10964473) MGI MGI:MGI:1889107 , PMID:10964473 embryonic limb morphogenesis IGI MGI:MGI:103302 2290270 (MGI:MGI:1270933, PMID:9664686) MGI MGI:MGI:1270933 , PMID:9664686 embryonic limb morphogenesis IMP MGI:MGI:1857137 2290270 (MGI:MGI:1270933, PMID:9664686) MGI MGI:MGI:1270933 , PMID:9664686 embryonic morphogenesis IMP MGI:MGI:3041440 , MGI:MGI:2176835 2290270 (MGI:MGI:3574741, PMID:15716346) MGI MGI:MGI:3574741 , PMID:15716346 embryonic skeletal joint morphogenesis IGI MGI:MGI:103302 2290270 (MGI:MGI:1270933, PMID:9664686) MGI MGI:MGI:1270933 , PMID:9664686 embryonic skeletal joint morphogenesis IMP MGI:MGI:1857137 2290270 (MGI:MGI:1270933, PMID:9664686) MGI MGI:MGI:1270933 , PMID:9664686 embryonic skeletal system development IMP MGI:MGI:2158495 2290270 (MGI:MGI:3640733, PMID:16712836) MGI MGI:MGI:3640733 , PMID:16712836 embryonic skeletal system morphogenesis IMP MGI:MGI:2158495 2290270 (MGI:MGI:3640733, PMID:16712836) MGI MGI:MGI:3640733 , PMID:16712836 endocardial cushion development IMP 2290270 (MGI:MGI:3814273, PMID:18924235) BHF-UCL MGI:MGI:3814273 , PMID:18924235 endochondral ossification IMP 2290270 (MGI:MGI:4418577, PMID:20059955) UniProtKB MGI:MGI:4418577 , PMID:20059955 endoderm development IDA 2290270 (MGI:MGI:5705244, PMID:24835669) MGI MGI:MGI:5705244 , PMID:24835669 epithelial cell proliferation involved in lung morphogenesis ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 epithelial to mesenchymal transition involved in endocardial cushion formation NOT IMP 2290270 (MGI:MGI:3814273, PMID:18924235) BHF-UCL MGI:MGI:3814273 , PMID:18924235 epithelial tube branching involved in lung morphogenesis ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 epithelial-mesenchymal cell signaling IDA 2290270 (MGI:MGI:83888, PMID:8104708) MGI MGI:MGI:83888 , PMID:8104708 epithelium development IDA 2290270 (MGI:MGI:83672, PMID:8898217) MGI MGI:MGI:83672 , PMID:8898217 erythrocyte differentiation IDA 2290270 (MGI:MGI:3578483, PMID:15591122) MGI MGI:MGI:3578483 , PMID:15591122 eye development NOT IGI UniProtKB:P23359 2290270 (MGI:MGI:3610441, PMID:16154126) UniProtKB MGI:MGI:3610441 , PMID:16154126 forebrain development IGI MGI:MGI:2137520 2290270 (MGI:MGI:3043486, PMID:14681194) MGI MGI:MGI:3043486 , PMID:14681194 forebrain development IMP MGI:MGI:1857137 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 germ cell development IMP MGI:MGI:1857137 2290270 (MGI:MGI:3050161, PMID:15289457) MGI MGI:MGI:3050161 , PMID:15289457 glomerular capillary formation IMP 2290270 (MGI:MGI:3849375, PMID:18272846) UniProtKB MGI:MGI:3849375 , PMID:18272846 glomerular visceral epithelial cell development IEP 2290270 (PMID:17442697) UniProtKB PMID:17442697 heart development IMP MGI:MGI:3042751 2290270 (MGI:MGI:3039210, PMID:15070745) MGI MGI:MGI:3039210 , PMID:15070745 heart development IMP MGI:MGI:2181190 2290270 (MGI:MGI:2677659, PMID:12975322) MGI MGI:MGI:2677659 , PMID:12975322 hematopoietic progenitor cell differentiation IDA 2290270 (MGI:MGI:70235, PMID:7799920) MGI MGI:MGI:70235 , PMID:7799920 hematopoietic progenitor cell differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 inner ear receptor cell differentiation IGI MGI:MGI:95524 2290270 (MGI:MGI:3714221, PMID:17555714) MGI MGI:MGI:3714221 , PMID:17555714 intermediate mesodermal cell differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 kidney development IMP MGI:MGI:1857137 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 kidney development IGI UniProtKB:P23359 2290270 (MGI:MGI:3610441, PMID:16154126) UniProtKB MGI:MGI:3610441 , PMID:16154126 kidney development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 lens induction in camera-type eye IMP MGI:MGI:1857137 2290270 (MGI:MGI:1316914, PMID:9851982) MGI MGI:MGI:1316914 , PMID:9851982 lung alveolus development ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 lung development IMP MGI:MGI:2181190 , MGI:MGI:3574949 2290270 (MGI:MGI:3618437, PMID:16414041) MGI MGI:MGI:3618437 , PMID:16414041 lung lobe development ISO RGD:2213 9068941 RGD PMID:15991191 , REF_RGD_ID:8916959 lung morphogenesis ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 lymphoid progenitor cell differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 macrophage differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 mammary gland formation IMP 2290270 (MGI:MGI:3695659, PMID:17071745) MGI MGI:MGI:3695659 , PMID:17071745 membranous septum morphogenesis IMP 2290270 (MGI:MGI:3039210 more ... BHF-UCL MGI:MGI:3039210 more ... mesenchymal cell differentiation involved in kidney development IMP 2290270 (MGI:MGI:3710018, PMID:17442697) UniProtKB MGI:MGI:3710018 , PMID:17442697 mesenchymal cell differentiation involved in renal system development IMP 2290270 (MGI:MGI:3710018, PMID:17442697) UniProtKB MGI:MGI:3710018 , PMID:17442697 mesenchymal cell proliferation involved in ureter development IEP 2290270 (PMID:17442697) UniProtKB PMID:17442697 mesenchymal cell proliferation involved in ureteric bud development IEP 2290270 (PMID:17442697) UniProtKB PMID:17442697 mesenchymal to epithelial transition involved in metanephros morphogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 mesoderm formation IDA 2290270 (MGI:MGI:4415813 more ... MGI MGI:MGI:4415813 more ... mesodermal cell differentiation IDA 2290270 (MGI:MGI:70235, PMID:7799920) MGI MGI:MGI:70235 , PMID:7799920 mesodermal cell fate determination IMP MGI:MGI:1857137 2290270 (MGI:MGI:76261, PMID:7657163) MGI MGI:MGI:76261 , PMID:7657163 mesonephros development ISO RGD:730832 9068941 (PMID:18437684) UniProtKB PMID:18437684 metanephric collecting duct development IMP 2290270 (MGI:MGI:3710018, PMID:17442697) UniProtKB MGI:MGI:3710018 , PMID:17442697 metanephros development IDA 2290270 (MGI:MGI:2655937, PMID:12631064) MGI MGI:MGI:2655937 , PMID:12631064 metanephros development IMP MGI:MGI:2158495 2290270 (MGI:MGI:2655937, PMID:12631064) MGI MGI:MGI:2655937 , PMID:12631064 monocyte differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 multicellular organism development IEA UniProtKB-KW:KW-0217 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 muscular septum morphogenesis NOT IMP 2290270 (MGI:MGI:3814273, PMID:18924235) BHF-UCL MGI:MGI:3814273 , PMID:18924235 negative regulation of apoptotic process ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of apoptotic process IBA PANTHER:PTN002626129 2290270 (MGI:MGI:6201960, PMID:21873635) GO_Central MGI:MGI:6201960 , PMID:21873635 negative regulation of apoptotic process IMP 2290270 (MGI:MGI:2655937, PMID:12631064) UniProtKB MGI:MGI:2655937 , PMID:12631064 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of branching involved in ureteric bud morphogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of branching involved in ureteric bud morphogenesis IGI MGI:MGI:102780 2290270 (MGI:MGI:4949995, PMID:21281623) MGI MGI:MGI:4949995 , PMID:21281623 negative regulation of branching involved in ureteric bud morphogenesis IDA 2290270 (MGI:MGI:3525902, PMID:15634693) UniProtKB MGI:MGI:3525902 , PMID:15634693 negative regulation of cell cycle ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of cell death ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of cell population proliferation ISO UniProtKB:P12644 2290270 (MGI:MGI:892820, PMID:9187146) MGI MGI:MGI:892820 , PMID:9187146 negative regulation of cell population proliferation IGI MGI:MGI:104327 2290270 (MGI:MGI:3771245, PMID:18028901) MGI MGI:MGI:3771245 , PMID:18028901 negative regulation of cell proliferation involved in heart morphogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of chondrocyte differentiation IDA 2290270 (MGI:MGI:3714677, PMID:17481601) MGI MGI:MGI:3714677 , PMID:17481601 negative regulation of epithelial cell proliferation IMP MGI:MGI:1857137 2290270 (MGI:MGI:1934513, PMID:11401393) MGI MGI:MGI:1934513 , PMID:11401393 negative regulation of extrinsic apoptotic signaling pathway IMP 2290270 (MGI:MGI:3039210, PMID:15070745) BHF-UCL MGI:MGI:3039210 , PMID:15070745 negative regulation of gene expression IDA 2290270 (MGI:MGI:2135612, PMID:11493558) MGI MGI:MGI:2135612 , PMID:11493558 negative regulation of gene expression ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of glomerular mesangial cell proliferation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of glomerulus development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of immature T cell proliferation in thymus ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of MAP kinase activity ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of mesenchymal cell proliferation involved in ureter development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of metanephric comma-shaped body morphogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of metanephric S-shaped body morphogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of mitotic nuclear division ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of myoblast differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 negative regulation of oligodendrocyte differentiation ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 negative regulation of phosphorylation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of pri-miRNA transcription by RNA polymerase II ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of prostatic bud formation IMP MGI:MGI:1857137 2290270 (MGI:MGI:1934513, PMID:11401393) MGI MGI:MGI:1934513 , PMID:11401393 negative regulation of prostatic bud formation IDA 2290270 (MGI:MGI:3785350, PMID:18393306) MGI MGI:MGI:3785350 , PMID:18393306 negative regulation of striated muscle tissue development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 negative regulation of T cell differentiation in thymus ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of thymocyte apoptotic process ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of transcription by RNA polymerase II ISO UniProtKB:P12644 2290270 (MGI:MGI:892820, PMID:9187146) MGI MGI:MGI:892820 , PMID:9187146 negative regulation of transcription by RNA polymerase II IBA PANTHER:PTN002626129 2290270 (MGI:MGI:6201960, PMID:21873635) GO_Central MGI:MGI:6201960 , PMID:21873635 negative regulation of transcription by RNA polymerase II IMP 2290270 (MGI:MGI:3039210, PMID:15070745) BHF-UCL MGI:MGI:3039210 , PMID:15070745 negative regulation of transcription by RNA polymerase II IDA 2290270 (MGI:MGI:1205964, PMID:9585504) MGI MGI:MGI:1205964 , PMID:9585504 negative regulation of transcription, DNA-templated ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 neural tube closure IDA 2290270 (MGI:MGI:4429763, PMID:19850029) MGI MGI:MGI:4429763 , PMID:19850029 neuron fate commitment IMP MGI:MGI:2158495 2290270 (MGI:MGI:3761972, PMID:17698011) MGI MGI:MGI:3761972 , PMID:17698011 neuron fate commitment IDA 2290270 (MGI:MGI:3761972, PMID:17698011) MGI MGI:MGI:3761972 , PMID:17698011 odontogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 odontogenesis of dentin-containing tooth IGI MGI:MGI:1913292 2290270 (MGI:MGI:3603904, PMID:16179481) MGI MGI:MGI:3603904 , PMID:16179481 odontogenesis of dentin-containing tooth IDA 2290270 (MGI:MGI:3513220 more ... MGI MGI:MGI:3513220 more ... organ induction IMP MGI:MGI:1857137 2290270 (MGI:MGI:1306869, PMID:9806931) MGI MGI:MGI:1306869 , PMID:9806931 ossification IEA UniProtKB-KW:KW-0892 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 osteoblast differentiation IDA 2290270 (MGI:MGI:3525426, PMID:15381701) MGI MGI:MGI:3525426 , PMID:15381701 osteoblast differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 outflow tract morphogenesis IGI RNAcentral:URS000075EEC2_10090 2290270 (MGI:MGI:4939577, PMID:21145505) BHF-UCL MGI:MGI:4939577 , PMID:21145505 outflow tract morphogenesis IGI RNAcentral:URS00002075FA_10090, RNAcentral:URS0000574A2C_10090 2290270 (MGI:MGI:4939577, PMID:21145505) BHF-UCL MGI:MGI:4939577 , PMID:21145505 outflow tract septum morphogenesis IMP 2290270 (MGI:MGI:3039210 more ... BHF-UCL MGI:MGI:3039210 more ... ovarian follicle development ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 pharyngeal arch artery morphogenesis IMP 2290270 (MGI:MGI:3039210, PMID:15070745) BHF-UCL MGI:MGI:3039210 , PMID:15070745 pituitary gland development IMP MGI:MGI:1857137 2290270 (MGI:MGI:1306869, PMID:9806931) MGI MGI:MGI:1306869 , PMID:9806931 positive regulation of apoptotic process ISO UniProtKB:P12644 2290270 (MGI:MGI:892820, PMID:9187146) MGI GO_REF:0000096 more ... positive regulation of BMP signaling pathway IDA 2290270 (MGI:MGI:4418577, PMID:20059955) UniProtKB MGI:MGI:4418577 , PMID:20059955 positive regulation of bone mineralization ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 positive regulation of bone mineralization ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of branching involved in lung morphogenesis IMP 2290270 (MGI:MGI:4456940, PMID:17350185) UniProtKB MGI:MGI:4456940 , PMID:17350185 positive regulation of branching involved in ureteric bud morphogenesis ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of calcium ion transport into cytosol ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of cardiac muscle fiber development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis IGI UniProtKB:P23359 2290270 (MGI:MGI:5502250, PMID:23863481) BHF-UCL MGI:MGI:5502250 , PMID:23863481 positive regulation of cartilage development ISO UniProtKB:P12644 2290270 (MGI:MGI:63446, PMID:3201241) MGI MGI:MGI:63446 , PMID:3201241 positive regulation of cell death ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 positive regulation of cell differentiation IDA 2290270 (MGI:MGI:3513220, PMID:15525533) MGI MGI:MGI:3513220 , PMID:15525533 positive regulation of cell migration IMP 2290270 (MGI:MGI:5619689, PMID:24603907) CACAO MGI:MGI:5619689 , PMID:24603907 positive regulation of cell population proliferation IMP MGI:MGI:2158495 2290270 (MGI:MGI:3820452, PMID:18692041) MGI MGI:MGI:3820452 , PMID:18692041 positive regulation of cell population proliferation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of cell population proliferation ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of cell proliferation involved in outflow tract morphogenesis IMP 2290270 (MGI:MGI:3039210, PMID:15070745) BHF-UCL MGI:MGI:3039210 , PMID:15070745 positive regulation of collagen biosynthetic process ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of endothelial cell apoptotic process ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of endothelial cell differentiation IDA 2290270 (MGI:MGI:4830635, PMID:20406889) DFLAT MGI:MGI:4830635 , PMID:20406889 positive regulation of endothelial cell migration TAS 2290270 (MGI:MGI:4830635, PMID:20406889) DFLAT MGI:MGI:4830635 , PMID:20406889 positive regulation of endothelial cell migration ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of endothelial cell proliferation IDA 2290270 (MGI:MGI:4830635, PMID:20406889) DFLAT MGI:MGI:4830635 , PMID:20406889 positive regulation of endothelial cell proliferation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of epidermal cell differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of epithelial cell proliferation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of epithelial to mesenchymal transition IGI UniProtKB:P23359 2290270 (MGI:MGI:5502250, PMID:23863481) BHF-UCL MGI:MGI:5502250 , PMID:23863481 positive regulation of ERK1 and ERK2 cascade IDA 2290270 (MGI:MGI:3820452, PMID:18692041) MGI MGI:MGI:3820452 , PMID:18692041 positive regulation of gene expression IMP MGI:MGI:1857137 2290270 (MGI:MGI:3805418, PMID:18622394) MGI MGI:MGI:3805418 , PMID:18622394 positive regulation of gene expression ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of gene expression IDA 2290270 (MGI:MGI:5619472, PMID:19001364) CACAO MGI:MGI:5619472 , PMID:19001364 positive regulation of hepatocyte differentiation ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of kidney development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of mesenchymal stem cell proliferation ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of neuron differentiation IDA 2290270 (MGI:MGI:1307014, PMID:9786991) MGI MGI:MGI:1307014 , PMID:9786991 positive regulation of neuron differentiation ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of neuron projection development ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of ossification ISO UniProtKB:Q06826 2290270 (MGI:MGI:67505, PMID:7911662) MGI MGI:MGI:67505 , PMID:7911662 positive regulation of ossification ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of ossification ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 positive regulation of ossification IDA 2290270 (MGI:MGI:63654, PMID:8358941) MGI MGI:MGI:63654 , PMID:8358941 positive regulation of osteoblast differentiation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 positive regulation of osteoblast differentiation ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of pathway-restricted SMAD protein phosphorylation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of pathway-restricted SMAD protein phosphorylation IBA PANTHER:PTN000218063 2290270 (MGI:MGI:6201960, PMID:21873635) GO_Central MGI:MGI:6201960 , PMID:21873635 positive regulation of pri-miRNA transcription by RNA polymerase II IGI UniProtKB:P21274 2290270 (MGI:MGI:4939577, PMID:21145505) BHF-UCL MGI:MGI:4939577 , PMID:21145505 positive regulation of production of miRNAs involved in gene silencing by miRNA ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of protein binding ISO UniProtKB:P12644 2290270 (MGI:MGI:5499270, PMID:23610558) MGI MGI:MGI:5499270 , PMID:23610558 positive regulation of protein phosphorylation IMP MGI:MGI:2158495 2290270 (MGI:MGI:3820452, PMID:18692041) MGI MGI:MGI:3820452 , PMID:18692041 positive regulation of protein phosphorylation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 positive regulation of SMAD protein signal transduction ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of smooth muscle cell proliferation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of store-operated calcium channel activity ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of transcription by RNA polymerase II ISO UniProtKB:Q06826 2290270 (MGI:MGI:67505, PMID:7911662) MGI MGI:MGI:67505 , PMID:7911662 positive regulation of transcription by RNA polymerase II IMP 2290270 (MGI:MGI:3039210, PMID:15070745) BHF-UCL MGI:MGI:3039210 , PMID:15070745 positive regulation of transcription by RNA polymerase II IDA 2290270 (MGI:MGI:1197794 more ... MGI MGI:MGI:1197794 more ... positive regulation of transcription by RNA polymerase II IGI MGI:MGI:97168 2290270 (MGI:MGI:1336531 more ... MGI MGI:MGI:1336531 more ... positive regulation of transcription by RNA polymerase II ISO UniProtKB:P12644 2290270 (MGI:MGI:892820, PMID:9187146) MGI GO_REF:0000096 more ... positive regulation of transcription by RNA polymerase II IMP MGI:MGI:2158495 2290270 (MGI:MGI:3820452, PMID:18692041) MGI MGI:MGI:3820452 , PMID:18692041 positive regulation of transcription, DNA-templated TAS 2290270 (MGI:MGI:4830635, PMID:20406889) DFLAT MGI:MGI:4830635 , PMID:20406889 positive regulation of transcription, DNA-templated ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of vascular endothelial growth factor receptor signaling pathway TAS 2290270 (MGI:MGI:4830635, PMID:20406889) DFLAT MGI:MGI:4830635 , PMID:20406889 post-embryonic development ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 post-embryonic development IMP MGI:MGI:1857137 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 prostate gland morphogenesis IMP MGI:MGI:1857137 2290270 (MGI:MGI:1095762 more ... MGI MGI:MGI:1095762 more ... protein localization to nucleus ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 pulmonary artery endothelial tube morphogenesis ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 pulmonary valve morphogenesis IMP 2290270 (MGI:MGI:3039210 more ... BHF-UCL MGI:MGI:3039210 more ... regulation of branching involved in prostate gland morphogenesis IMP MGI:MGI:2158495 2290270 (MGI:MGI:3575593, PMID:15772937) MGI MGI:MGI:3575593 , PMID:15772937 regulation of cartilage development IDA 2290270 (MGI:MGI:4830625, PMID:20501701) MGI MGI:MGI:4830625 , PMID:20501701 regulation of cell differentiation IGI MGI:MGI:95586 2290270 (MGI:MGI:3513220, PMID:15525533) MGI MGI:MGI:3513220 , PMID:15525533 regulation of cell differentiation ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 regulation of cell fate commitment ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 regulation of endothelial cell proliferation TAS 2290270 (MGI:MGI:4830635, PMID:20406889) DFLAT MGI:MGI:4830635 , PMID:20406889 regulation of ERK1 and ERK2 cascade ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 regulation of gene expression IDA 2290270 (MGI:MGI:1353953, PMID:10704389) MGI MGI:MGI:1353953 , PMID:10704389 regulation of gene expression IMP 2290270 (MGI:MGI:2135527, PMID:11436557) MGI MGI:MGI:2135527 , PMID:11436557 regulation of morphogenesis of a branching structure IMP MGI:MGI:1857137 2290270 (MGI:MGI:1934513, PMID:11401393) MGI MGI:MGI:1934513 , PMID:11401393 regulation of odontogenesis of dentin-containing tooth IGI MGI:MGI:99604 , MGI:MGI:88177 2290270 (MGI:MGI:894889, PMID:9244299) MGI MGI:MGI:894889 , PMID:9244299 regulation of pathway-restricted SMAD protein phosphorylation ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 regulation of pri-miRNA transcription by RNA polymerase II NOT ISO RGD:730832 9068941 (PMID:18548003) BHF-UCL PMID:18548003 regulation of protein import into nucleus ISO UniProtKB:P12644 2290270 (MGI:MGI:5426342, PMID:22529382) MGI MGI:MGI:5426342 , PMID:22529382 regulation of smooth muscle cell differentiation IGI MGI:MGI:1347470 2290270 (MGI:MGI:3766861, PMID:17881493) MGI MGI:MGI:3766861 , PMID:17881493 regulation of smooth muscle cell differentiation IDA 2290270 (MGI:MGI:3766861, PMID:17881493) MGI MGI:MGI:3766861 , PMID:17881493 regulation of smooth muscle cell proliferation IDA 2290270 (MGI:MGI:3578606, PMID:15800000) MGI MGI:MGI:3578606 , PMID:15800000 renal system process IMP MGI:MGI:1857137 2290270 (MGI:MGI:1095762, PMID:9268572) MGI MGI:MGI:1095762 , PMID:9268572 response to estradiol ISO RGD:2213 9068941 RGD PMID:16551644 more ... response to glucocorticoid ISO RGD:2213 9068941 RGD PMID:17537984 , REF_RGD_ID:1643596 response to mechanical stimulus ISO RGD:2213 9068941 RGD PMID:10404008 more ... response to nitric oxide ISO RGD:2213 9068941 RGD PMID:15991191 , REF_RGD_ID:8916959 response to organic cyclic compound ISO RGD:2213 9068941 RGD PMID:12730624 , REF_RGD_ID:2289016 response to retinoic acid ISO RGD:2213 9068941 RGD PMID:8385738 , REF_RGD_ID:2289028 response to testosterone ISO RGD:2213 9068941 RGD PMID:20660069 , REF_RGD_ID:4144839 retina development in camera-type eye ISO RGD:2213 9068941 RGD PMID:17069773 , REF_RGD_ID:2289001 secondary heart field specification ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 skeletal system development IDA 2290270 (MGI:MGI:2683812, PMID:14654219) MGI MGI:MGI:2683812 , PMID:14654219 skeletal system development IMP MGI:MGI:3041440 , MGI:MGI:2654594 2290270 (MGI:MGI:3583479, PMID:15936012) MGI MGI:MGI:3583479 , PMID:15936012 SMAD protein signal transduction IDA 2290270 (MGI:MGI:1195384, PMID:9420335) MGI MGI:MGI:1195384 , PMID:9420335 SMAD protein signal transduction IBA PANTHER:PTN000218063 2290270 (MGI:MGI:6201960, PMID:21873635) GO_Central MGI:MGI:6201960 , PMID:21873635 SMAD protein signal transduction ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 smooth muscle cell differentiation IDA 2290270 (MGI:MGI:3624584, PMID:16546160) MGI MGI:MGI:3624584 , PMID:16546160 smooth muscle tissue development IMP 2290270 (MGI:MGI:2655937, PMID:12631064) UniProtKB MGI:MGI:2655937 , PMID:12631064 specification of animal organ position IMP 2290270 (MGI:MGI:3695659, PMID:17071745) MGI MGI:MGI:3695659 , PMID:17071745 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 steroid hormone mediated signaling pathway ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 telencephalon development ISO UniProtKB:P12644 2290270 (MGI:MGI:892820, PMID:9187146) MGI MGI:MGI:892820 , PMID:9187146 telencephalon regionalization IGI MGI:MGI:96785 2290270 (MGI:MGI:2154554, PMID:11719201) MGI MGI:MGI:2154554 , PMID:11719201 telencephalon regionalization IDA 2290270 (MGI:MGI:3640853, PMID:16855091) MGI MGI:MGI:3640853 , PMID:16855091 tendon cell differentiation IMP 2290270 (MGI:MGI:4418577, PMID:20059955) UniProtKB MGI:MGI:4418577 , PMID:20059955 tissue development IGI MGI:MGI:2137520 2290270 (MGI:MGI:3043486, PMID:14681194) MGI MGI:MGI:3043486 , PMID:14681194 tongue morphogenesis ISO RGD:2213 9068941 RGD PMID:16828469 , REF_RGD_ID:2289002 trachea development ISO UniProtKB:P12644 2290270 (MGI:MGI:81070, PMID:8674409) MGI MGI:MGI:81070 , PMID:8674409 trachea formation IMP MGI:MGI:3797048 2290270 (MGI:MGI:3820452, PMID:18692041) MGI MGI:MGI:3820452 , PMID:18692041 type B pancreatic cell development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 ureter epithelial cell differentiation IMP 2290270 (MGI:MGI:3710018, PMID:17442697) UniProtKB MGI:MGI:3710018 , PMID:17442697 ureter smooth muscle cell differentiation IMP 2290270 (MGI:MGI:3710018, PMID:17442697) UniProtKB MGI:MGI:3710018 , PMID:17442697 ureteric bud development IMP MGI:MGI:2158495 2290270 (MGI:MGI:2655937, PMID:12631064) MGI MGI:MGI:2655937 , PMID:12631064 ureteric bud development ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 ureteric bud development IDA 2290270 (MGI:MGI:2655937, PMID:12631064) MGI MGI:MGI:2655937 , PMID:12631064 vasculature development IMP MGI:MGI:2158495 2290270 (MGI:MGI:3766861, PMID:17881493) MGI MGI:MGI:3766861 , PMID:17881493 wound healing ISO RGD:2213 9068941 RGD PMID:21142982 , REF_RGD_ID:9068405 Cellular Component cytoplasm ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 extracellular region IDA 2290270 (MGI:MGI:63654, PMID:8358941) MGI MGI:MGI:63654 , PMID:8358941 extracellular space IDA 2290270 (MGI:MGI:3714677, PMID:17481601) MGI MGI:MGI:3714677 , PMID:17481601 extracellular space IBA PANTHER:PTN000218063 2290270 (MGI:MGI:6201960, PMID:21873635) GO_Central MGI:MGI:6201960 , PMID:21873635 extracellular space ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 extracellular space ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 vesicle ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 Molecular Function BMP receptor binding ISO UniProtKB:P12644 2290270 (MGI:MGI:70105, PMID:7811286) MGI MGI:MGI:70105 , PMID:7811286 BMP receptor binding IBA PANTHER:PTN002626129 2290270 (MGI:MGI:6201960, PMID:21873635) GO_Central MGI:MGI:6201960 , PMID:21873635 chemoattractant activity ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 co-receptor binding ISO UniProtKB:P12644 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 cytokine activity ISO UniProtKB:P12644 2290270 MGI GO_REF:0000008, MGI:MGI:2154458 cytokine activity IBA PANTHER:PTN000218063 2290270 (MGI:MGI:6201960, PMID:21873635) GO_Central MGI:MGI:6201960 , PMID:21873635 growth factor activity ISO RGD:2213 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 heparin binding IDA 2290270 (MGI:MGI:3525426, PMID:15381701) MGI MGI:MGI:3525426 , PMID:15381701 identical protein binding ISO RGD:2213 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 protein binding IPI UniProtKB:Q8CF09 2290270 (MGI:MGI:2681048, PMID:14623234) MGI MGI:MGI:2681048 , PMID:14623234 protein binding IPI MGI:MGI:2137520 2290270 (MGI:MGI:3525426, PMID:15381701) MGI MGI:MGI:3525426 , PMID:15381701 protein binding IPI PR:Q6PCX7 2290270 (MGI:MGI:3590430, PMID:15975920) MGI MGI:MGI:3590430 , PMID:15975920 protein binding IPI PR:Q9R118 2290270 (MGI:MGI:3034116, PMID:14973287) MGI MGI:MGI:3034116 , PMID:14973287 protein binding IPI PR:Q8VEA6 2290270 (MGI:MGI:2683044, PMID:14660436) MGI MGI:MGI:2683044 , PMID:14660436 protein binding IPI PR:Q8CJ69 2290270 (MGI:MGI:2670247, PMID:12897139) MGI MGI:MGI:2670247 , PMID:12897139 protein binding IPI UniProtKB:Q9D236 2290270 (MGI:MGI:3046453, PMID:15206957) UniProtKB MGI:MGI:3046453 , PMID:15206957 protein binding IPI UniProtKB:A2ARV4 2290270 (MGI:MGI:3525818, PMID:15623804) UniProtKB MGI:MGI:3525818 , PMID:15623804
Gene-Chemical Interaction Annotations
