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Gene: Bmp4 (bone morphogenetic protein 4) Mus musculus
Symbol: Bmp4
Name: bone morphogenetic protein 4
RGD ID: 10244
Description: Exhibits heparin binding activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and regulation of animal organ morphogenesis. Localizes to extracellular space. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; genitourinary system; and sensory organ. Used to study Axenfeld-Rieger syndrome type 3; atrioventricular septal defect; cleft palate-lateral synechia syndrome; fibrodysplasia ossificans progressiva; and urinary system disease. Human ortholog(s) of this gene implicated in several diseases, including CAKUT (multiple); cleft lip; orofacial cleft 11; ossification of the posterior longitudinal ligament of spine; and otosclerosis. Orthologous to human BMP4 (bone morphogenetic protein 4).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Bmp-; BMP-2B; Bmp-4; Bmp2; Bmp2b; Bmp2b-; Bmp2b-1; Bmp2b1; bone morphogenetic protein 2B
Homo sapiens (human) : BMP4 (bone morphogenetic protein 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bmp4 (bone morphogenetic protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmp4 (bone morphogenetic protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : BMP4 (bone morphogenetic protein 4)
Canis lupus familiaris (dog) : BMP4 (bone morphogenetic protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmp4 (bone morphogenetic protein 4)
Sus scrofa (pig) : BMP4 (bone morphogenetic protein 4)
Chlorocebus sabaeus (African green monkey) : BMP4 (bone morphogenetic protein 4)
Heterocephalus glaber (naked mole-rat) : Bmp4 (bone morphogenetic protein 4)
more info ...
Related Pseudogenes: Bmp4-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1446,383,520 - 46,390,669 (-)EnsemblGRCm38mm10GRCm38
GRCm381446,383,525 - 46,390,669 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371447,003,195 - 47,010,274 (-)NCBIGRCm37mm9NCBIm37
MGSCv361445,305,736 - 45,309,065 (-)NCBImm8
Celera1442,555,453 - 42,562,519 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1423.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Bmp4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10244
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-15
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.