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Gene: Nqo1 (NAD(P)H dehydrogenase, quinone 1) Mus musculus
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Symbol: Nqo1
Name: NAD(P)H dehydrogenase, quinone 1
Description: Exhibits NAD(P)H dehydrogenase (quinone) activity. Involved in negative regulation of catalytic activity and response to oxidative stress. Predicted to localize to cytosol; dendrite; and neuronal cell body. Is expressed in heart; olfactory epithelium; and skin. Human ortholog(s) of this gene implicated in several diseases, including asthma; hematologic cancer (multiple); lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1); PARTICIPATES IN doxorubicin pharmacokinetics pathway; nuclear factor, erythroid 2 like 2 signaling pathway; oxidative stress response pathway; INTERACTS WITH (-)-demecolcine; (-)-epigallocatechin 3-gallate; (RS)-coclaurine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AV001255; azoreductase; Dia4; diaphorase 4 (NADH/NADPH); DT-diaphorase; Dtd; menadione reductase; NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase [quinone] 1; NAD(P)H menadione oxidoreductase 1, dioxin inducible; NAD(P)H:quinone oxidoreductase 1; Nmo-1; Nmo1; Nmor1; Ox-1; Ox1; phylloquinone reductase; Qr1; quinone reductase 1
Orthologs:
Homo sapiens (human) : NQO1 (NAD(P)H quinone dehydrogenase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nqo1 (NAD(P)H quinone dehydrogenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nqo1 (NAD(P)H quinone dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NQO1 (NAD(P)H quinone dehydrogenase 1)
Canis lupus familiaris (dog) : NQO1 (NAD(P)H quinone dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nqo1 (NAD(P)H quinone dehydrogenase 1)
Sus scrofa (pig) : NQO1 (NAD(P)H quinone dehydrogenase 1)
Chlorocebus sabaeus (African green monkey) : NQO1 (NAD(P)H quinone dehydrogenase 1)
Heterocephalus glaber (naked mole-rat) : Nqo1 (NAD(P)H quinone dehydrogenase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl8107,388,225 - 107,403,206 (-)EnsemblGRCm38mm10GRCm38
GRCm388107,388,225 - 107,403,205 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378109,912,125 - 109,927,105 (-)NCBIGRCm37mm9NCBIm37
MGSCv368110,277,349 - 110,292,395 (-)NCBImm8
Celera8111,617,929 - 111,633,856 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map854.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations